Search clinical trials for: Scopolamine

Total 114 results

Pfizer

Terminated

Assessment Of The Effects Of Single Doses Of An Investigational Drug, Given Alone Or With Donepezil, On Scopolamine-Induced Changes In Memory And Learning In Healthy Adults

Healthy

United States
Repurposed Therapeutics, Inc.

Unknown

Nasal Gel Under Military Operational Conditions for the Prevention of Nausea Associated With Motion Sickness

Motion Sickness

United States
Bukwang Pharmaceutical

Terminated

A Study to Evaluate the Efficacy and the Change of sAg Levels in Chronic Hepatitis B Patients Receiving Clevudine Treatment Over the Long Period

Chronic Hepatitis B

Korea, Republic of
GlaxoSmithKline

Completed

A Comparative Bioavailability and Adhesion Performance Study, Comparing a New Scopolamine Transdermal Delivery System Formulation to the Currently Established Reference Transdermal Delivery System in Healthy Adult Participants.

Motion Sickness

Canada
Merck Sharp & Dohme LLC

Completed

Placebo-Controlled Crossover Study to Evaluate Donepezil and MK-3134 for Reversal of Cognitive Impairment Associated With Scopolamine Administration (3134-005)(COMPLETED)

Dementia
Daniela Moga
National Institute on Aging (NIA)

Completed

The INCREASE Study - Delaying the Onset of Alzheimer's Symptomatic Expression (INCREASE)

Dementia | Alzheimer's Disease

United States
Repurposed Therapeutics, Inc.

Completed

The Prevention and Treatment of Nausea Associated With Motion Sickness

Motion Sickness

United States
Mentis Cura
Landspitali University Hospital

Completed

The Use of EEG in Alzheimer's Disease, With and Without Scopolamine - A Pilot Study

AD
Tetra Discovery Partners

Completed

Study to Evaluate the Effects of BPN14770 on Scopolamine-induced Cognitive Impairment in Healthy Volunteers

Alzheimer Disease

United States
University of Texas Southwestern Medical Center
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Pharmacological Modulation of Brain Oscillations in Memory Processing

Epilepsy | Seizures | Memory Disorders | Memory Loss | Cognitive Impairment, Mild

United States
Repurposed Therapeutics, Inc.

Completed

Efficacy and Safety of DPI-386 Nasal Gel for the Prevention of Nausea and Vomiting Associated With Motion

Motion Sickness

United States
Repurposed Therapeutics, Inc.
Defender Pharmaceuticals, Inc.

Completed

Nasal Gel for the Prevention of Nausea and Vomiting Associated With Motion

Motion Sickness

United States
Repurposed Therapeutics, Inc.

Unknown

Scopolamine in Healthy Volunteers

Major Depressive Disorder (MDD)

United States
National Institute of Mental Health (NIMH)

Terminated

Cholinergic Modulation of Condition and Emotion in Mood Disorders: Functional Neuroimaging Studies

Mood Disorders | Healthy | Bipolar Depression | Unipolar Depression

United States
Battelle Memorial Institute

Terminated

A Study to Evaluate the Intramuscular Administration of Scopolamine

Scopolamine Causing Adverse Effects in Therapeutic Use

United States
University of Iowa
University of Minnesota

Completed

Scopolamine Patch Pharmacokinetics in Healthy Adults

Healthy

United States
Millennium Pharmaceuticals, Inc.

Completed

An Efficacy and Safety Study of Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine in Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML) and Low-Blast Acute Myelogenous Leukemia (AML)

Myelodysplastic Syndromes | Leukemia, Myeloid, Acute | Leukemia, Myelomonocytic, Chronic

United States, Israel, Spain, France, Ireland, Canada, Germany, Czechia, Italy, Netherlands, Belgium, Bulgaria
Rutgers, The State University of New Jersey

Unknown

Scopolamine Patch and Acupressure Point P6 Stimulation for Reduction of Nausea and Vomiting During Cesarean Section

Nausea | Vomiting | Satisfaction

United States
Shandong University

Completed

The Application of Spasmolytic in PCLE Examination of Superior Gastrointestinal Endoscope

Using Copolamine Butylbromide in Probe-based Confocal Laser Endomicroscopy for Gastroendoscopy Examination

China
Alexander M Spiess, MD

Completed

A Novel Usage of Transdermal Scopolamine in Reducing Narcotic Usage in Outpatient Hand Surgery

Post Operative Pain Management

United States
Drexel University
Merck Sharp & Dohme LLC

Completed

Comparison of Aprepitant Versus Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting

Nausea | Vomiting

United States
Pfizer

Completed

Scopolamine Challenge Study

Healthy

France
Hospital de Clinicas de Porto Alegre

Unknown

Effect of Pre-medication in Pain Measures on Office Hysteroscopy

Pain

Brazil
Repurposed Therapeutics, Inc.
National Aeronautics and Space Administration (NASA)

Recruiting

Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance

Motion Sickness | Sea Sickness | Motion Sickness, Space

United States
Vanderbilt University Medical Center

Completed

Mental Ability Challenge Study in Adults With and Without HIV

Cognitive Impairment | Memory Impairment | HIV-1-infection | Aging, Premature | HIV-Associated Cognitive Motor Complex

United States
Naval Aeromedical Research Unit, Dayton

Unknown

Study of the Safety and Efficacy of DPI-386 Nasal Gel on Ocean-Going Vessels (INSCOP)

Prevention of Nausea Associated With Motion Sickness | Treatment of Nausea Associated With Motion Sickness

United States
Drexel University College of Medicine
Merck Sharp & Dohme LLC

Completed

Comparison of Oral Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting

Nausea | Vomiting

United States
The Taub Group

Completed

The Safety and Efficacy of Naltrexone and Scopolamine Utilized in the Treatment of Major Depression

Depression

United States
Changhai Hospital

Completed

Drotaverine Hydrochloride Versus Hyoscine-N-butylbromide for Duodenal Antimotility During Endoscopic Retrograde Cholangiopancreatography (ERCP)

Pancreatic Diseases | Bile Duct Diseases | ERCP

China
Takeda

Terminated

TAK-071 Scopolamine-Induced Cognitive Impairment Study

Healthy Volunteers

United States
Sunnybrook Health Sciences Centre

Completed

Safety and Efficacy of Nabilone in Alzheimer's Disease

Pain | Weight Loss | Alzheimer Disease | Oxidative Stress | Agitation

Canada
National Institute of Allergy and Infectious Diseases...

Completed

A Multicenter Dose Ranging Clinical Trial of 2',3'-Dideoxycytidine in the Treatment of Patients With AIDS and Advanced ARC.

HIV Infections

United States
Hoffmann-La Roche

Completed

Dideoxycytidine ( Ro 24-2027 ). A Treatment Protocol for the Use of Dideoxycytidine ( ddC ) in Patients With AIDS or Advanced ARC Who Cannot Be Maintained on Zidovudine ( AZT ) Therapy.

HIV Infections

United States
Repurposed Therapeutics, Inc.
National Aeronautics and Space Administration (NASA)

Recruiting

Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance

Motion Sickness, Space | Motion Simulation | Parabolic Flight

United States
Medical Corps, Israel Defense Force

Unknown

A Double-blind Comparison of Scopolamine With Cinnarizin for Prevention of Simulator Sickness

Simulator Sickness

Israel
Hoffmann-La Roche

Completed

A Randomized, Open-Label Study of Alternative Treatment Combinations of Dideoxycytidine (HIVID; ddC) and Zidovudine (AZT) in Patients With HIV Infection

HIV Infections

United States
EMS

Withdrawn

Efficacy and Safety of Escócia Association in the Treatment of Acute Pain

Acute Pain
Lena Nilsson

Completed

Patient-controlled Sedation With Propofol Versus Combined Sedation During Bronchoscopy

Sedation, Bronchoscopy
French National Agency for Research on AIDS and...
Gilead Sciences; Pharmasset

Terminated

ANRS HB 05 Multicenter Study Evaluating Efficacy and Safety of Clevudine Monotherapy Versus Tenofovir Monotherapy Versus Combination Therapy of Clevudine and Tenofovir for 96 Weeks in HBeAg Negative Patients With Chronic Hepatitis B, naïve to Anti-VHB Therapy

HBe Negative Chronic Hepatitis B | Hepatitis B Viral Infection

France
Boston University
Centers for Disease Control and Prevention

Completed

Effects of Transdermal Scopolamine on Occupational Performance

Motion Sickness

Sweden
Dr. Brian Hallahan
Stanley Medical Research Institute; National University of Ireland, Galway,... and other collaborators

Recruiting

Scopolamine in Bipolar Depression (SCOPE-BD)

Bipolar Disorder Depression

Ireland
Repurposed Therapeutics, Inc.

Terminated

Pharmacokinetic and Efficacy Profile Intranasal Scopolamine Spray

Motion Sickness

United States
National Institute of Mental Health (NIMH)

Terminated

The Antidepressant Efficacy of the Anticholinergic Scopolamine

Bipolar Depression | Unipolar Depression

United States
Dartmouth-Hitchcock Medical Center

Recruiting

Nebulizer Delivery of Intranasal Scopolamine

Motion Sickness | Scopolamine

United States
Boehringer Ingelheim

Completed

Determine the Bioequivalence of Two Formulations of Hyoscine Butylbromide.

Healthy

Canada
Repurposed Therapeutics, Inc.

Completed

Nasal Gel for the Prevention and Treatment of Nausea Associated With Motion Sickness

Motion Sickness

United States
Ain Shams University

Recruiting

Effect of Hyoscine- Bromide on Duration of the First Stage of Labor

Labor

Egypt
University of California, Los Angeles

Completed

Generalization of Extinction Learning

Social Anxiety Disorder

United States
Boehringer Ingelheim

Completed

Study to Evaluate Efficacy and Safety of Oral Doses of Hyoscine Butylbromide for the Treatment of Occasional Abdominal Pain, Cramping, and Discomfort

Colic
Massachusetts General Hospital

Terminated

A Study of the Use of IV Scopolamine to Augment the Efficacy of Electroconvulsive Therapy (ECT)

Depression

United States

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