Search clinical trials for: whole genomic

Total 2763 results

Nantes University Hospital
Inserm UMR1087, CNRS UMR6291; Clinique des Données, CIC 1413, CHU Nantes; CIC-FEA...

Recruiting

Genetics of Ventriculo-arterial Discordance (PreciPed)

Heart Defects, Congenital

France
Kocaeli University

Completed

Gene Expression Profiles in Chronic Periodontitis

Chronic Periodontitis
Xiaofan Zhu

Available

Use Massive Parallel Sequencing and Exome Capture Technology to Sequence the Exome of Fanconi Anemia Children and Their Patents

Fanconi Anemia | Autosomal or Sex Linked Recessive Genetic Disease | Bone Marrow Hematopoiesis Failure, Multiple Congenital Abnormalities, and Susceptibility to Neoplastic Diseases. | Hematopoiesis Maintainance.

China
British Columbia Cancer Agency

Not yet recruiting

PATH Trial: Personalized Approaches in the Treatment of Head and Neck Cancer (PATH)

Head and Neck Cancer
Tufts Medical Center
University of Pittsburgh; Children's Hospital Medical Center, Cincinnati; MOUNT... and other collaborators

Completed

Genomic Medicine for Ill Neonates and Infants (The GEMINI Study) (GEMINI)

Pediatric: Genetic Syndrome

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics

Malignant Solid Neoplasm | Breast Carcinoma | Lung Carcinoma | Colorectal Carcinoma | Ovarian Carcinoma | Pancreatic Carcinoma | Prostate Carcinoma

United States
Children's Hospital of Fudan University

Not yet recruiting

Whole Genome Sequencing Versus Whole Exome Sequencing for Congenital Diarrhea and Enteropahty

Diarrhea, Infantile | Enteropathy
Thomas Jefferson University

Recruiting

Whole Exome Sequencing and Whole Genome Sequencing for Nonimmune Fetal/Neonatal Hydrops

Genetic Disorders | Nonimmune Fetal Hydrops | Nonimmune Hydrops in Neonate

United States
GeneCast Biotechnology Co., Ltd.
The First Affiliated Hospital of Air Force Military Medical University (Xijing...

Recruiting

Gastric Cancer Early Detection by Multi-dimensional Analysis of cfDNA

Gastric Cancer

China
Boston Children's Hospital
National Eye Institute (NEI)

Recruiting

Genetic Studies of Strabismus, Nystagmus, and Associated Disorders

Strabismus | Nystagmus, Congenital

United States
Institut National de la Santé Et de la Recherche...
Hospices Civils de Lyon; University Hospital, Rouen; Centre Hospitalier Universitaire... and other collaborators

Active, not recruiting

Genome Sequencing Strategies for Genetics Diagnosis of Patients With Intellectual Disability (DEFIDIAG)

Intellectual Disability

France
UMC Utrecht
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Glioblastoma Targeted Treatment Option Maximization by WGS (GLOW)

Glioblastoma

Netherlands
Aalborg University Hospital
Aarhus University Hospital; ARCEDI Biotech

Completed

Cell-based Non-invasive Prenatal Testing as an Alternative to Invasive Chorionic Villus Sampling

Hereditary Diseases

Denmark
University of California, San Francisco
Johns Hopkins University; Eunice Kennedy Shriver National Institute of Child... and other collaborators

Enrolling by invitation

Uncovering the Etiologies of Non-immune Hydrops Fetalis

Non-Immune Hydrops Fetalis

United States
London School of Hygiene and Tropical Medicine
Wellcome Sanger Institute

Completed

Global Syphilis Sequencing

Syphilis

United Kingdom
Nantes University Hospital
AXA Assurances VIE Mutuelle

Not yet recruiting

Identification of Genetic Variants Associated With Unexpected Infant Death Syndrome (BIOMINRISK)

Sudden Infant Death | Sudden Unexplained Infant Death

France
University of Cambridge
Illumina, Inc.; Rosetrees Trust; Isaac Newton Trust; NIHR Cambridge Biomedical...

Recruiting

NeuralNET Cerebral Palsy Pilot Study

Cerebral Palsy

United Kingdom
Istituto Superiore di Sanità
Fondazione G.B. Bietti, IRCCS; Ospedale Pediatrico Bambin Gesù

Recruiting

Mechanisms of Inherited Retinal Dystrophies Using Whole Genome Sequencing and in Vitro and in Vivo Models

Retinitis Pigmentosa | Macular Dystrophy | Inherited Retinal Dystrophy

Italy
Children's Mercy Hospital Kansas City

Recruiting

United States Hypophosphatasia Molecular Research Center

Hypophosphatasia

United States
Nanfang Hospital of Southern Medical University
Ferring Pharmaceuticals

Unknown

Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve

Diminished Ovarian Reserve

China
Massachusetts General Hospital
Broad Institute; Laboratory for Molecular Medicine

Completed

Investigating the Feasibility and Implementation of Whole Genome Sequencing in Patients With Suspected Genetic Disorder

Genetic Predisposition to Disease | Hereditary Disease

United States
Seoul National University Hospital

Unknown

WGS of Korean Idiopathic Bronchiectasis (WGS_UNK_BE)

Cystic Fibrosis | Bronchiectasis Idiopathic | Primary Ciliary Dyskinesia

Korea, Republic of
Xinhua Hospital, Shanghai Jiao Tong University...

Unknown

Whole Genome Sequencing in the Detection of Rare Undiagnosed Genetic Diseases in Children in China

Intellectual Disability | Rare Diseases | Multiple Congenital Anomaly

China
Neuromed IRCCS

Not yet recruiting

Implementing a National Biobank of PD With WGS and Functional Assessment of Polygenic Inheritance by iPSC Technology

Parkinson Disease | REM Sleep Behavior Disorder

Italy
Dana-Farber Cancer Institute
Johns Hopkins University; M.D. Anderson Cancer Center; Mayo Clinic; University... and other collaborators

Active, not recruiting

GENetic Education Risk Assessment and TEsting Study (GENERATE)

Candidates for Hereditary Pancreatic Cancer Testing

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

Does the Use of a Genomic Tumor Board Increase the Number of Patients Who Receive Genome-Informed Treatment

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Puerto Rico
University Health Network, Toronto
Western University, Canada; Public Health Ontario Laboratory, Canada

Recruiting

M. Avium WGS During Mav-PD Treatment

Respiratory Tract Diseases | Mycobacterium Infections | Mycobacterium Infections, Nontuberculous | Nontuberculous Mycobacterial Lung Disease | Mycobacterium Avium

Canada
Baylor College of Medicine

Completed

Genetic Inclusion by Virtual Evaluation (GIVE)

Neurodevelopmental Disorders | Birth Defects | Multiple Congenital Anomaly

United States
Blood Donation Service Zurich, SRC

Unknown

Whole Genome Sequencing for Blood Group Genotyping and Definition as Exemplified on U- and St(a)+. (Blood Genome)

Genetic Blood Group (bg) Polymorphism in U Negativity and St(a) of MNSs

Switzerland
Illumina, Inc.

Active, not recruiting

NeuroSeq: A Prospective Trial to Evaluate the Diagnostic Yield of Whole Genome Sequencing (WGS) in Adult Neurology (NeuroSEQ)

Neurologic Disorder | Neurologic Deficits | Neurologic Abnormalities

United States
Jagiellonian University
Poznan University of Medical Sciences; Medical University of Warsaw

Completed

Whole Exome Sequencing in Coronary Artery Ectasia

Coronary Aneurysm | Coronary Ectasia

Poland
Institut National de la Santé Et de la Recherche...
Commissariat A L'energie Atomique; Imagine Institute

Completed

Decoding Developmental Disorders in Humams (devodecode)

Genetic Diseases

France
Nantes University Hospital

Completed

Study of cardiovAscular Contrasted Phenotypes in Patients With FamIliaI hypercholesteRolemia (SAFIR)

Homozygous Familial Hypercholesterolemia

France
Children's Mercy Hospital Kansas City

Completed

Genomic Sequencing in Acutely Ill Neonates (NSIGHT)

Genetic Disease | Diseases/Diagnoses

United States
University Hospital, Montpellier

Completed

Fast Exome for Diagnosis of Congenital Conditions in Infants Under 12 Months of Age Hospitalized in Intensive Care Unit (REUNIR)

Infant, Newborn, Diseases | Intensive Care Unit | Neurologic Symptoms | Congenital Malformations

France
Peter MacCallum Cancer Centre, Australia
National Health and Medical Research Council, Australia; University of Melbourne

Recruiting

Diagnosis and Phenotype Characterisation Using Genomics in Patients With Inherited Bone Marrow Failure (IBMDx Study) (IBMDx)

Hematologic Diseases | Inherited Platelet Disorder | Inherited BMF Syndrome

Australia
Sydney Children's Hospitals Network
Children's Cancer Institute Australia

Recruiting

Cancer Predisposition Testing by Family-based Whole-genome Sequencing (WGS) in Every Child With Newly Diagnosed Cancer (PREDICT)

Cancer | Neoplastic Syndromes, Hereditary | Genetic Predisposition to Disease

Australia
University Health Network, Toronto

Recruiting

Molecular Characteristics of Gastroesophageal Adenocarcinoma (MOCHA): A Prospective Feasibility Study (MOCHA)

Esophagogastric Adenocarcinoma

Canada
University of Illinois College of Medicine at Peoria
Rady Children's Institute of Genomic Medicine

Active, not recruiting

Utility of Rapid Whole Genome Sequencing in the NICU: A Pilot Study

Genetic Disease | Genetic Syndrome

United States
Illumina, Inc.
Children's Hospital of Philadelphia; St. Louis Children's Hospital; Children's... and other collaborators

Completed

NICUSeq: A Trial to Evaluate the Clinical Utility of Human Whole Genome Sequencing (WGS) Compared to Standard of Care in Acute Care Neonates and Infants (NICU-Seq)

Rare Diseases

United States
Peking Union Medical College Hospital

Unknown

Clinical Application of ctDNA in Early Screening of Breast Cancer

Breast Cancer
Steno Diabetes Center Greenland
Zealand University Hospital; University of Copenhagen

Recruiting

Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland

Diabetes Mellitus, Type 2 | Diabetic Neuropathies | Diabetic Retinopathy | Obstructive Sleep Apnea | Obesity, Morbid | MODY

Greenland
Geneplus-Beijing Co. Ltd.
Beijing Hospital; Emergency General Hospital

Recruiting

Benign/Malignant Pulmonary Nodule Classification Based on High-throughput Whole-genome Methylation Sequencing(GM-seq)

Pulmonary Nodule, Solitary | Whole-genome Methylation Sequencing

China
Kaiser Permanente
National Human Genome Research Institute (NHGRI)

Completed

Clinical Implementation of Carrier Status Using Next Generation Sequencing (NextGen)

Genetic Disorders

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Federico II University; Istituto Auxologico Italiano; Università degli Studi...

Recruiting

Maternal Genes and Epimutations: Beckwith-Wiedemann Syndrome & Reproductive Risks

Beckwith-Wiedemann Syndrome

Italy
University Hospital, Basel, Switzerland

Completed

Whole Genome Single Nucleotide Polymorphisms in Elderly Patients With Postoperative Cognitive Dysfunction (GenPOCD)

Postoperative Cognitive Dysfunction

Switzerland
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Nanjing Geneseeq Technology Inc.

Recruiting

Early Detection of Endometrial Cancer Using Plasma Cell-free DNA Fragmentomics

Endometrial Cancer

China
Boston Children's Hospital

Recruiting

Genetics of Epilepsy and Related Disorders

Epilepsy | Dravet Syndrome | Infantile Spasms | Epileptic Encephalopathy | Ohtahara Syndrome | Early Myoclonic Epileptic Encephalopathy | PCDH19-related Epilepsy and Related Conditions | KCNQ2-Related Epileptic Encephalopathy | Epilepsy of Infancy With Migrating Focal Seizures (Disorder)

United States
Rady Pediatric Genomics & Systems Medicine Institute

Active, not recruiting

Newborn Genomic Sequencing Pilot Study

Genetic Disease

United States
University of California, San Diego

Withdrawn

Development of an Optimal Approach to Return of Results for Next-generation Sequencing for Prenatal Diagnosis

Major Fetal Anomaly

United States

Search clinical trials for: whole genomic

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