Clinical Trials Sponsored by AL-S Pharma

Total 96 results

AL-S Pharma

Recruiting

A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Korea, Republic of, United States, Canada, Germany, Sweden, Belgium
AL-S Pharma

Unknown

A Study to Evaluate AP-101 in Familial and Sporadic Amyotrophic Lateral Sclerosis (ALS)

Amyotrophic Lateral Sclerosis

Canada
S Form Pharma

Recruiting

Longitudinal Observational Study for mIddle Term Follow-up Patients Admitted for Acute Dyspnea in TunIsia (SIDI)

Longitudinal Observational Study With 6 Months Follow-up

Tunisia
Ascendis Pharma Growth Disorders A/S

Recruiting

A Clinical Trial to Evaluate Efficacy and Safety of TransCon CNP Compared With Placebo in Infants (0 to <2 Years of Age) With Achondroplasia

Achondroplasia

United States, Australia
Ascendis Pharma Oncology Division A/S

Recruiting

A Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors

Advanced Solid Tumor | Metastatic Solid Tumor | Locally Advanced Solid Tumor | Neoadjuvant Melanoma | Head and Neck Squamous Cell Carcinoma HNSCC | HPV-associated Cancers | Neoadjuvant Cutaneous Squamous Cell Carcinoma (cSCC)

United States, Australia, Spain, Netherlands, Korea, Republic of, Taiwan
Ascendis Pharma Growth Disorders A/S

Enrolling by invitation

A Clinical Trial to Investigate Long-term Safety, Tolerability, and Efficacy of Weekly Subcutaneous Doses With TransCon CNP in Children and Adolescents With Achondroplasia (AttaCH)

Achondroplasia

United States, Australia, Denmark, Ireland, Austria, Germany, New Zealand
Ascendis Pharma Endocrinology Division A/S

Completed

A Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency (foresiGHt)

Endocrine System Diseases | Growth Hormone Deficiency | Hormone Deficiency

United States, Armenia, Georgia, Turkey, Ukraine, Australia, Canada, Denmark, France, Germany, Greece, Israel, Italy, Japan, Korea, Republic of, Malaysia, Netherlands, New Zealand, Poland, Romania, Serbia, Slovakia, Spain, United Kingdom
Ascendis Pharma Oncology Division A/S

Recruiting

TransCon (TC) TLR7/8 Agonist, TC IL-2 β/γ, Pembrolizumab Prior to Surgery for Advanced Head and Neck Squamous Cell Carcinoma (BelieveIT-201)

Head and Neck Neoplasms

United States, Spain, Georgia, Italy, Hungary, Germany
Ascendis Pharma Endocrinology Division A/S

Recruiting

A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA (SkybriGHt)

Growth Hormone Deficiency

United States
Ascendis Pharma Endocrinology Division A/S

Recruiting

A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin (SkyPASS)

Growth Hormone Deficiency

United States
Ascendis Pharma Endocrinology Division A/S

Recruiting

A Trial to Investigate Different Doses of Lonapegsomatropin Compared to Somatropin in Individuals With Turner Syndrome

Turner Syndrome

United States
Ascendis Pharma Growth Disorders A/S

Active, not recruiting

A Clinical Trial to Evaluate Efficacy and Safety of TransCon CNP Compared With Placebo in Children With Achondroplasia (ApproaCH)

Achondroplasia

United States, Denmark, Ireland, New Zealand, Australia, Canada, Spain
Ascendis Pharma Endocrinology Division A/S

Active, not recruiting

A Trial to Investigate Long Term Efficacy and Safety of Lonapegsomatropin in Adults With Growth Hormone Deficiency

Endocrine System Diseases | Adult Growth Hormone Deficiency | Hormone Deficiency

United States, Armenia, Georgia, Greece, Ukraine, Australia, Canada, France, Israel, Italy, Japan, Malaysia, Poland, Romania, Serbia, Slovakia, Spain, Turkey, United Kingdom, Germany, Korea, Republic of
Ascendis Pharma Endocrinology Division A/S

Completed

A Safety, Tolerability and Efficacy Study of TransCon hGH in Children With Growth Hormone Deficiency

Endocrine System Diseases | Pituitary Diseases | Hormone Deficiency | Growth Hormone Deficiency, Pediatric

United States, Canada, Australia, New Zealand
MedTrace Pharma A/S

Recruiting

RAdiolabeled Perfusion to Identify Coronary Artery Disease Using WAter To Evaluate Responses of Myocardial FLOW (RAPID-WATER-FLOW)

Coronary Artery Disease

United States, Sweden, Denmark, Canada
Ascendis Pharma A/S

Completed

A Multi-center, Longitudinal, Observational Study of Children With Achondroplasia

Achondroplasia

United States, Australia, Austria, Germany, China, Canada, Denmark, France, Ireland, Italy, New Zealand, Portugal, Spain, Switzerland, United Kingdom
Ascendis Pharma A/S

Active, not recruiting

A Dose Escalation Trial Evaluating Safety, Efficacy, and Pharmacokinetics of Multiple Subcutaneous Doses of TransCon CNP Administered Once Weekly in Children With Achondroplasia

Achondroplasia

China
Ascendis Pharma A/S

Completed

A Long-Term Trial Investigating Safety and Efficacy of TransCon hGH in Children With Growth Hormone Deficiency Who Have Completed a Prior TransCon hGH Clinical Trial (enliGHten)

Endocrine System Diseases | Pituitary Diseases | Hormone Deficiency | Growth Hormone Deficiency, Pediatric

United States, Armenia, Belarus, Bulgaria, Georgia, Greece, Russian Federation, Ukraine, Australia, New Zealand, Poland
Fertin Pharma A/S

Completed

Single-Dose Bioequivalence Study Comparing Two 2 mg Nicotine Lozenges

Smoking Cessation

South Africa
7TM Pharma A/S

Terminated

A Study to Determine the Effects of TM30339 on Weight Loss in Obese Individuals.

Obesity
Santaris Pharma A/S

Completed

Multiple Ascending Dose Study of SPC4955 in Healthy Subjects

Hypercholesterolemia

Germany
Ascendis Pharma A/S

Completed

Pharmacokinetics and Pharmacodynamics of ACP-001 (TransCon PEG hGH)

Healthy

Canada
Santaris Pharma A/S

Completed

Safety Study of SPC3649 in Healthy Men

Hepatitis C

Denmark
Ascendis Pharma Oncology Division A/S

Recruiting

A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or Chemotherapy or TransCon TLR7/8 Agonist in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies (IL Believe)

Advanced Solid Tumor | Metastatic Solid Tumor | Platinum-resistant Ovarian Cancer | Locally Advanced Solid Tumor | Post Anti-PD-1 Melanoma | 2L+ Cervical Cancer | Neoadjuvant Melanoma | Neoadjuvant Non-Small Cell Lung Cancer | Post Anti-PD-(L)1 Non-Small Cell Lung Cancer | Post Anti-PD-(L)1 Small Cell...

United States, Australia, Korea, Republic of
Ascendis Pharma Bone Diseases A/S

Active, not recruiting

A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH Administered Daily in Adults With Hypoparathyroidism (PaTHway)

Endocrine System Diseases | Parathyroid Diseases | Hypoparathyroidism

United States, Canada, Norway, Denmark, Germany, Hungary, Italy
Ascendis Pharma Endocrinology Division A/S

Completed

A Phase 3 Trial of the Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)

Endocrine System Diseases | Pituitary Diseases | Hormones | Growth Hormone Deficiency, Pediatric | hGH (Human Growth Hormone)

United States, Armenia, Australia, Belarus, Bulgaria, Georgia, Greece, Italy, New Zealand, Poland, Romania, Russian Federation, Turkey, Ukraine
Contera Pharma A/S

Not yet recruiting

Open-Label Extension Study of ASTORIA

Dyskinesias
Ascendis Pharma A/S

Active, not recruiting

A Dose Escalation Trial Evaluating Safety, Efficacy, and Pharmacokinetics of TransCon CNP Administered Once Weekly in Prepubertal Children With Achondroplasia

Achondroplasia

United States, Australia, Austria, Denmark, Germany, Ireland, New Zealand, Portugal
Ascendis Pharma A/S

Active, not recruiting

A Trial Investigating the Safety, Tolerability and Efficacy of TransCon PTH in Adults With Hypoparathyroidism (PaTH Forward)

Endocrine System Diseases | Parathyroid Diseases | Hypoparathyroidism

United States, Canada, Denmark, Germany, Italy, Norway
Ascendis Pharma A/S

Terminated

A Safety, Tolerability and Pharmacokinetics Study of TransCon Treprostinil in Healthy Adult Male Volunteers

Healthy Volunteers
Fertin Pharma A/S

Completed

Single-Dose Bioequivalence Study Comparing Two 4 mg Nicotine Lozenges

Smoking Cessation

South Africa
Fertin Pharma A/S

Completed

Comparison of Pharmacokinetic Profiles of 3 New Nicotine Gum Formulations With a Reference Gum

Smoking Cessation
Santaris Pharma A/S

Unknown

Miravirsen Study in Null Responder to Pegylated Interferon Alpha Plus Ribavirin Subjects With Chronic Hepatitis C

Hepatitis C

Puerto Rico
Santaris Pharma A/S

Completed

SPC3649 Multiple Dose Study in Healthy Volunteers

Hepatitis C

Netherlands
Action Pharma A/S

Completed

Pharmacokinetics of AP214 Acetate in Patients Undergoing Cardiac Surgery

Valve Surgery | Cardiac Surgery | Coronary Artery Bypass Grafting | Aortic Root or Ascending Aortic Aneurysm Repair Surgery

Denmark
Astion Pharma A/S

Completed

Efficacy and Safety of ASF1057 in the Treatment of Seborrhoeic Dermatitis

Seborrheic Dermatitis
Astion Pharma A/S

Completed

Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions (2)

Discoid Lupus Erythematosus

Denmark
Astion Pharma A/S

Completed

Efficacy and Safety of ASF-1096 Cream 0.5% in the Treatment of Discoid Lupus Erythematosus (DLE) Lesions

Discoid Lupus Erythematosus

Sweden
NMD Pharma A/S

Recruiting

Safety and Efficacy of NMD670 in Ambulatory Adult Patients With Type 3 Spinal Muscular Atrophy (SYNAPSE-SMA)

Spinal Muscular Atrophy

United States, Spain, Belgium, Denmark, Germany, Netherlands, Italy, Canada
Ascendis Pharma A/S

Completed

A Safety, Pharmacokinetic and Pharmacodynamic Study of ACP-001 (TransCon hGH) in Adults With Growth Hormone Deficiency

Adult Growth Hormone Deficiency

Sweden, Denmark, Germany, Italy
Ascendis Pharma A/S

Completed

Safety, PK/PD (Pharmacokinetics/Pharmacodynamics) and Efficacy of ACP-001 Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)

Growth Hormone Deficiency (GHD)

Egypt, Turkey, Germany, Poland, France, Hungary, Russian Federation, Ukraine, Belarus, Bulgaria, Czech Republic, Greece, Romania, Slovenia
Santaris Pharma A/S

Unknown

Miravirsen in Combination With Telaprevir and Ribavirin in Null Responder to Pegylated-Interferon Alpha Plus Ribavirin Subjects With Chronic Hepatitis C Virus Infection

Hepatitis C, Chronic

Puerto Rico, United States
Santaris Pharma A/S

Completed

Drug Interaction Study to Assess the Effect of Co-Administered Miravirsen and Telaprevir in Healthy Subjects

Hepatitis C | Chronic Hepatitis C

United States
Action Pharma A/S

Completed

An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Surgery

Kidney Diseases | Coronary Artery Bypass | Valve Surgery | Cardiac Surgery | Aortic Aneurysm

Denmark
Santaris Pharma A/S

Completed

Multiple Ascending Dose Study of Miravirsen in Treatment-Naïve Chronic Hepatitis C Subjects

Hepatitis C

United States, Germany, Netherlands, Poland, Puerto Rico, Slovakia
Santaris Pharma A/S

Terminated

Multiple Ascending Dose Study of SPC5001 in Treatment of Healthy Subjects and Subjects With FH

Hypercholesterolemia

Netherlands
Santaris Pharma A/S

Completed

SPC2996 in Chronic Lymphocytic Leukaemia

Chronic Lymphocytic Leukemia

France, Denmark, United Kingdom, United States
Action Pharma A/S

Terminated

Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery

Valve Surgery | Cardiac Surgery | Kidney Injury | Coronary Artery Bypass Grafting

United States
Université de Sherbrooke
Eli Lilly and Company; Chorus Wellness Inc.; AL-S Pharma AG

Recruiting

Safety and Dosimetry of a New Radiotracer to Detect Misfolded SOD1 Associated With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

Canada
Genuine Research Center, Egypt
Al-debeiky pharma

Completed

A Bio-equivalence Study of Sofosbuvir From Sofodelevier 400 mg Film Coated Tablets (Al-debeiky Pharma, Egypt) Versus Sovaldi 400 mg Tablets (Gilead Sciences, Canada)

Healthy

Egypt

Clinical Trials Sponsored by AL-S Pharma

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Netherlands

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations