Clinical Trials Sponsored by Achelios Therapeutics

Total 6478 results

Achelios Therapeutics

Completed

Study to Determine the Efficacy and Safety of ELS-M11 in Acute Migraine

Migraine Headaches

United States
Actelion

Active, not recruiting

A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension (SALTO)

Hypertension, Pulmonary

United States, Belgium, Korea, Republic of, Taiwan, Canada, Israel, Russian Federation, Switzerland, France, Thailand, Poland, China, Hungary, Spain, Turkey, Belarus, Germany, Serbia, Bulgaria, Brazil, Mexico, Italy, Sweden, Ireland, Ma... and more
Actelion

Terminated

A Study of Real-world Cohort of Pulmonary Arterial Hypertension (PAH) Participants (CARE PAH)

Pulmonary Arterial Hypertension

United States, Germany, Korea, Republic of, United Kingdom, China, Canada, Netherlands, Italy, Japan, Poland, Spain, Brazil, Malaysia, Argentina, Singapore, Puerto Rico, Sweden
Actelion

Completed

A Study of Selexipag in Participants Who Participated in a Previous Selexipag Study (SOMBRERO)

Hypertension, Pulmonary

Taiwan, Korea, Republic of, Belarus, India, Romania, Ukraine
Actelion

Active, not recruiting

A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Belgium, Taiwan, Israel, United States, France, China, United Kingdom, Malaysia, Belarus, Canada, Germany, Hungary, Russian Federation, Serbia, Ukraine, Poland
Actelion

Available

Individual Patient Expanded Access IND for Selexipag (Uptravi) in Participants With Non-healing Wound, Buerger's Disease

Thromboangiitis Obliterans | Non-healing Wound
Actelion

Completed

A Clinical Study to Investigate the Long-term Safety of the Drug Macitentan in Patients With Pulmonary Hypertension Who Were Previously Treated With Macitentan in Clinical Studies. (UMBRELLA)

Pulmonary Arterial Hypertension | Chronic Thromboembolic Pulmonary Hypertension

Belgium, France, Poland, Russian Federation, Belarus, Turkey, Ukraine
Actelion

Completed

A Study for the Identification of Biomarker Signatures for Diagnosis of Pulmonary Hypertension (PH) in Participants at Low or Intermediate Probability of PH Undergoing Cardiac Magnetic Resonance Imaging

Hypertension, Pulmonary

United Kingdom, Germany
Actelion

Terminated

Clinical Study to Compare the Efficacy and Safety of Ponesimod to Placebo in Subjects With Active Relapsing Multiple Sclerosis Who Are Treated With Dimethyl Fumarate (Tecfidera®) (POINT)

Multiple Sclerosis

United States, Germany, Hungary, Poland, United Kingdom, Australia, Austria, Belgium, Bulgaria, Canada, Czechia, Denmark, France, Greece, Italy, Mexico, Portugal, Russian Federation, Spain, Switzerland
Actelion

Completed

REPAIR: Right vEntricular Remodeling in Pulmonary ArterIal hypeRtension (REPAIR)

Pulmonary Arterial Hypertension

United States, Israel, France, Netherlands, Malaysia, Germany, Australia, United Kingdom, Hong Kong, Italy, Russian Federation, Singapore
Actelion

Completed

Clinical Study to Assess the Efficacy, Safety and Tolerability of Macitentan in Subjects With Inoperable Chronic Thromboembolic Pulmonary Hypertension (MERIT-1)

Chronic Thromboembolic Pulmonary Hypertension

United Kingdom, Belgium, Ukraine, Germany, Switzerland, Hungary, China, Korea, Republic of, Mexico, Czechia, France, Lithuania, Poland, Russian Federation, Thailand, Turkey
Actelion

Terminated

Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger Syndrome (MAESTRO-OL)

Pulmonary Arterial Hypertension

China, Malaysia, United States, Austria, Bulgaria, Chile, France, Germany, Greece, Mexico, Philippines, Poland, Portugal, Romania, Russian Federation, Serbia, Spain, United Kingdom, Vietnam
Actelion

Completed

Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument

Pulmonary Arterial Hypertension

United States
Actelion

Completed

A Clinical Study to Assess the Effect of Clopidogrel on the Pharmacokinetics of Selexipag and Its Active Metabolite in Healthy Male Subjects

Healthy Subjects

Belgium
Actelion

Completed

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile - Associated Diarrhea

Clostridium Difficile Infection

United States, Australia, Brazil, Canada, France, Germany, Italy, Netherlands, Peru, Poland, Romania, Spain
Actelion

Completed

Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger Syndrome (MAESTRO)

Pulmonary Arterial Hypertension

China, Malaysia, United States, Austria, Bulgaria, Chile, France, Germany, Greece, Israel, Mexico, Philippines, Poland, Portugal, Romania, Russian Federation, Serbia, Spain, Turkey, United Kingdom, Vietnam
Actelion

Completed

A Study to Compare the Macitentan-tadalafil Fixed Dose Combination Tablet Relative to the Concomitant Administration of the Reference Tablets of Macitentan and Tadalafil in Healthy Subjects

Healthy Subjects

Germany
Actelion

Terminated

Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients (DUAL-2)

Digital Ulcers

Spain, United States, Argentina, China, Ireland, Colombia, Israel, New Zealand, Germany, Belgium, Portugal, Netherlands, South Africa, Greece, Mexico, Poland, Puerto Rico, Russian Federation, Turkey, Ukraine, United Kingdom
Actelion

Completed

Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Patients With Scleroderma (RAPIDS-2)

Systemic Sclerosis | Digital Ulcers

United States, Canada
Actelion

Completed

A Study to Assess the Safety and Pharmacokinetics of Lucerastat (OGT 923) in Healthy Subjects

Healthy Subjects

United Kingdom
Actelion

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of Lucerastat (CDP923) After Multiple Dosing in Healthy Subjects

Healthy Subjects

United Kingdom
Actelion

Completed

A Clinical Study to Investigate the Effect of Gemfibrozil or Rifampicin on Blood Concentrations of Selexipag in Healthy Subjects

Healthy Subjects

Germany
Actelion

Completed

Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH) (Compass-2)

Pulmonary Arterial Hypertension

United States, Denmark, Sweden, Germany, Spain, Brazil, Saudi Arabia, Portugal, Greece, Slovakia, United Kingdom, Czech Republic
Actelion

Completed

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension (SERAPHIN)

Pulmonary Arterial Hypertension

United States, United Kingdom, Belarus, Argentina, Australia, Austria, Belgium, Bulgaria, Canada, Chile, China, Colombia, Croatia, France, Germany, Hong Kong, Hungary, India, Israel, Italy, Malaysia, Mexico, Netherlands, Norway, Peru, Poland and more
Actelion

Terminated

Persistent Pulmonary Hypertension of the Newborn (FUTURE 4)

Persistent Pulmonary Hypertension of the Newborn

United States, Australia, Belgium, Czech Republic, France, Germany, Korea, Republic of, Poland, Russian Federation, Singapore, Switzerland, United Kingdom
Actelion

Completed

Pulmonary Artery Remodelling With Bosentan

Hypertension, Pulmonary

Australia
Actelion

Completed

Epoprostenol for Injection (EFI/ACT-385781A) - Pulmonary Arterial Hypertension (EPITOME-2)

Pulmonary Arterial Hypertension

Spain, Belgium, France, Canada, Italy, Netherlands
Actelion

Completed

Study to Evaluate the Pharmacokinetics, Tolerability, and Safety of ACT-128800 in Japanese and Caucasian Healthy Male and Female Subjects

Healthy

United States
Actelion

Completed

Study of the Electrocardiographic Effects of Ponesimod in Healthy Male and Female Subjects

Healthy

United States
Actelion

Completed

REVEAL Registry™: Registry to Evaluate Early And Long-term PAH Disease Management

Pulmonary Hypertension

United States
Actelion

Completed

Epoprostenol for Injection in Pulmonary Arterial Hypertension - Extension of AC-066A401 (EPITOME-1 Ext)

Pulmonary Arterial Hypertension

United States
Actelion

Completed

Efficacy and Safety of Oral Bosentan in Pulmonary Arterial Hypertension Class II

Pulmonary Hypertension

United States, Netherlands, Canada, Spain, China, Belgium, Germany, Italy, United Kingdom, Switzerland, Australia, Austria, Czech Republic, France
Actelion

Completed

Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger Physiology

Pulmonary Arterial Hypertension Related to Eisenmenger Physiology

Canada, United Kingdom, Italy, United States, Netherlands, Australia, Austria, Belgium, France, Germany, Spain
Actelion

Terminated

Miglustat / OGT 918 in the Treatment of Cystic Fibrosis

Cystic Fibrosis

Spain
Actelion

Recruiting

A Study of Macitentan in Healthy Chinese Adult Male Participants

Healthy

China
Actelion

Recruiting

A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option (PLATYPUS)

Hypertension, Pulmonary

Korea, Republic of, Taiwan, Poland, Bulgaria, Ukraine, Belgium, South Africa, Belarus, Russian Federation
Actelion

Terminated

A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag (SPHINX)

Sarcoidosis-associated Pulmonary Hypertension

United States, Germany, Canada, United Kingdom, Belgium, France, Netherlands, Italy, Brazil, Spain
Actelion

Terminated

A Study to Evaluate Efficacy and Safety of Macitentan 75 mg in Inoperable or Persistent/Recurrent Chronic Thromboembolic Pulmonary Hypertension (MACiTEPH)

Chronic Thromboembolic Pulmonary Hypertension

United States, Germany, Japan, Korea, Republic of, Taiwan, Canada, United Kingdom, China, Austria, Italy, Bulgaria, Turkey, Spain, Thailand, Israel, Ukraine, Hungary, Mexico, Czechia, Russian Federation, France, Saudi Arabia, Singapore and more
Actelion

Completed

Clinical Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Ponesimod in Patients With Relapsing-remitting Multiple Sclerosis

Multiple Sclerosis

Poland, Ukraine, United Kingdom, United States, Germany, Spain, Bulgaria, Romania, Serbia, Canada, Finland, Sweden, Russian Federation, Hungary, Czechia, Netherlands, Israel, Switzerland, Austria, France
Actelion

Completed

Study of ACT-293987 (NS-304) in Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United Kingdom, Austria, Belgium, France, Germany, Hungary, Italy, Poland
Actelion

Completed

Oral Ponesimod Versus Teriflunomide In Relapsing MUltiple Sclerosis (OPTIMUM)

Multiple Sclerosis

United States, Belarus, Bosnia and Herzegovina, Bulgaria, Canada, Croatia, Czechia, Finland, France, Georgia, Germany, Greece, Hungary, Israel, Italy, Latvia, Lithuania, Mexico, Poland, Portugal, Romania, Russian Federation, Serbia, S... and more
Actelion

Completed

A Study of Two Macitentan Pediatric Formulations in Healthy Adult Participants

Healthy

Belgium
Actelion

Completed

Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects (RUBATO)

Congenital Heart Disease

United States, United Kingdom, Taiwan, Germany, France, Poland, China, Australia, Czechia, Canada, Denmark, New Zealand
Actelion

Completed

Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension (SERAPHIN OL)

Pulmonary Arterial Hypertension

United States, United Kingdom, Taiwan, Finland, Canada, Belarus, Belgium, Argentina, Australia, China, Colombia, Croatia, Germany, Hong Kong, India, Israel, Italy, Malaysia, Netherlands, Poland, Russian Federation, South Africa, Tha... and more
Actelion

Completed

Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of ACT-128800 in Patients With Relapsing-remitting Multiple Sclerosis

Multiple Sclerosis

United States, Australia, Austria, Belgium, Bulgaria, Canada, Czechia, Finland, France, Germany, Hungary, Israel, Italy, Netherlands, Poland, Romania, Russian Federation, Serbia, Spain, Sweden, Switzerland, Ukraine, United Kingdom
Actelion

Completed

A Registry for Patients Taking Uptravi (SPHERE)

Pulmonary Arterial Hypertension

United States, Puerto Rico
Actelion

Completed

The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension (TRITON)

Pulmonary Arterial Hypertension

United States, Spain, Denmark, Canada, Germany, United Kingdom, Belgium, Austria, Netherlands, Australia, France, Ireland, Sweden, Italy, Switzerland
Actelion

Completed

Effect of Selexipag on Daily Life Physical Activity of Patients With Pulmonary Arterial Hypertension. (TRACE)

Pulmonary Arterial Hypertension

United States, United Kingdom, Ireland, Germany, Austria, France, Norway, Portugal, Sweden, Switzerland
Actelion

Completed

A Study of Selexipag in Healthy Male Participant

Healthy

Belgium
Actelion

Completed

OPsumit USers Registry (OPUS)

Pulmonary Arterial Hypertension

United States, Puerto Rico

Clinical Trials Sponsored by Achelios Therapeutics

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Burundi

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations