Clinical Trials Sponsored by Achieve Life Sciences

Total 834 results

Achieve Life Sciences

Completed

A Second Study of Cytisinicline for Smoking Cessation in Adult Smokers (ORCA-3)

Smoking Cessation

United States
Achieve Life Sciences

Completed

Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics of a Single 3 mg Cytisinicline Dose

Renal Impairment

Spain, Portugal
Achieve Life Sciences

Completed

Trial of Cytisine in Adult Smokers

Smoking Cessation

United States
Achieve Life Sciences

Completed

A Study in Healthy Smokers to Investigate the Effect of Food on the Bioavailability of Cytisine in a New Formulation

Smoking Cessation

United Kingdom
Achieve Life Sciences

Completed

Study to Evaluate Electrocardiographic Effects of Therapeutic & Supratherapeutic Doses of Cytisinicline in Healthy Smokers

Smoking Cessation

Portugal
Achieve Life Sciences

Completed

A Single Dose-escalation Study of Cytisine in Adult Smokers

Smoking Cessation

Portugal
Achieve Life Sciences

Terminated

A Pharmacokinetic and Pharmacodynamic Evaluation of Cytisine in Healthy Smokers

Smoking Cessation

United Kingdom
Achieve Life Sciences

Completed

A Study in Healthy Volunteers to Investigate the Effect of Food on the Bioavailability of Cytisine

Smoking Cessation

United Kingdom
Achieve Life Sciences

Completed

Comparison of Cabazitaxel/Prednisone Alone or in Combination With Custirsen for 2nd Line Chemotherapy in Prostate Cancer (AFFINITY)

Prostate Cancer

France, United States, Canada, Australia, Hungary, Czech Republic, Russian Federation, United Kingdom
Achieve Life Sciences

Unknown

A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Advanced or Metastatic (Stage IV) Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

Taiwan, Spain, Israel, Italy, Korea, Republic of, New Zealand, Australia, Germany, United States, Hungary, Poland, Russian Federation, Singapore, Thailand, Ukraine
Achieve Life Sciences

Completed

Safety and Efficacy of S-8184 in Second Line Treatment of Stage III or IV Colorectal Adenocarcinoma

Colorectal Adenocarcinoma

Russian Federation
Achieve Life Sciences

Terminated

Comparison of Safety and Efficacy of TOCOSOL(R) Paclitaxel Versus Taxol(R) for Treatment of Metastatic Breast Cancer

Breast Neoplasm

United States
Achieve Life Sciences

Completed

Safety and Efficacy of S-8184 in Second Line Treatment of Stage III or IV Ovarian Cancer

Ovarian Cancer
Achieve Life Sciences

Completed

Safety and Efficacy of S-8184 in Second Line Treatment of Relapsed Stage IIIB or IV Non Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

Russian Federation
Achieve Life Sciences

Completed

A Study of Cytisinicline for Vaping Cessation in Adult Smokers (ORCA-V1)

Vaping | E-Cig Use

United States
Achieve Life Sciences

Completed

Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and Pharmacokinetics (PK) of Multiple 3 mg Doses in Healthy Adult Smokers

Smoking Cessation

Portugal
Achieve Life Sciences

Completed

A Study of Cytisinicline for Smoking Cessation in Adult Smokers (ORCA-2)

Smoking Cessation

United States
Achieve Life Sciences

Completed

Safety Study of an Antisense Product in Prostate, Ovarian, NSCL, Breast or Bladder Cancer

Neoplasms

United States, Canada
Achieve Life Sciences

Completed

Evaluation of Safety and Feasibility of OGX-011 in Combination With 2nd-line Chemotherapy in Patients With HRPC

Prostate Cancer

Canada
Achieve Life Sciences

Completed

A Study of OGX-011/Gemcitabine/Platinum-Based Regimen in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer

United States, Canada
Achieve Life Sciences

Completed

Phase 1 Dose Escalation Study of SN2310 Injectable Emulsion in Patients With Advanced Solid Tumors

Breast Neoplasms | Lung Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Pelvic Neoplasms

United States
Achieve Life Sciences

Completed

TOCOSOL(TM) Paclitaxel in Metastatic or Locally Advanced Unresectable Transitional Cell Carcinoma of the Urothelium

Carcinoma, Transitional Cell | Ureteral Neoplasms | Urethral Neoplasms | Bladder Neoplasms

United States
Achieve Life Sciences

Completed

Safety and Efficacy of S-8184 in Treatment of Locally Advanced, Metastatic, or Recurrent TCC of the Urothelium

Urologic Neoplasms
Achieve Life Sciences

Completed

Evaluation of Safety and Efficacy of TOCOSOL(R) Paclitaxel as Initial Treatment for Metastatic Breast Cancer

Breast Cancer

Russian Federation
Achieve Life Sciences
PRA Health Sciences

Completed

A Phase 2 Study Comparing Chemotherapy in Combination With OGX-427 or Placebo in Patients With Bladder Cancer

Urologic Neoplasms | Metastatic Bladder Cancer | Urinary Tract Neoplasms

Spain, United States, Canada, Italy, Poland, Germany, France
Achieve Life Sciences
Teva Pharmaceuticals USA

Terminated

A Study Evaluating the Pain Palliation Benefit of Adding Custirsen to Docetaxel Retreatment or Cabazitaxel as Second Line Therapy in Men With Metastatic Castrate Resistant Prostate Cancer (mCRPC)

Hormone Refractory Prostate Cancer | Castrate-Resistant Prostate Cancer

France, United States, Spain, United Kingdom, Canada
SCRI Development Innovations, LLC
Achieve Life Sciences

Completed

Phase II Trial of Carboplatin and Pemetrexed +/- OGX-427 in Untreated Stage IV Non-Squamous-Non-Small-Cell Lung Cancer (Spruce)

Non Squamous Non Small Cell Lung Cancer

United States
British Columbia Cancer Agency
Achieve Life Sciences

Completed

OGX-427 in Castration Resistant Prostate Cancer Patients

Castration Resistant Prostate Cancer

Canada, United States
SCRI Development Innovations, LLC
Achieve Life Sciences

Completed

Phase II Trial Of Gemcitabine Plus Nab-Paclitaxel +/- OGX-427 In Patients With Metastatic Pancreatic Cancer (Rainier)

Pancreatic Cancer

United States
Queen Mary University of London
Achieve Life Sciences

Unknown

Study of Gemcitabine/Carboplatin First-line Chemotherapy +/- Apatorsen in Advanced Squamous Cell Lung Cancers

Squamous Cell Lung Cancer

United Kingdom
Costantine Albany
Hoosier Cancer Research Network; Achieve Life Sciences

Terminated

OGX-427 in Metastatic Castrate-Resistant Prostate Cancer With Prostate-Specific Antigen Progression While Receiving Abiraterone

Prostate Cancer | PSA | Metastatic Castrate-Resistant Prostate Cancer

United States, Canada
Noah Hahn, M.D.
Hoosier Cancer Research Network; Achieve Life Sciences

Completed

Phase 2 Study of Docetaxel +/- OGX-427 in Patients With Relapsed or Refractory Metastatic Bladder Cancer

Bladder Cancer | Urothelial Carcinoma

United States
Achieve Life Sciences
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Thorough QT/QTc (Corrected QT Interval) Study to Evaluate the Effect of Custirsen on Cardiac Repolarization

Cardiac Conduction and Repolarization

United States
Achieve Life Sciences
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Clinical Study in Cancer Patients to Investigate the Potential Impact of Custirsen, on the Blood Levels of the Chemotherapeutic Drug, Paclitaxel, When Given Together as Part of a Treatment Regimen

Cancer

United States
Achieve Life Sciences
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Comparison of Docetaxel/Prednisone to Docetaxel/Prednisone in Combination With OGX-011 in Men With Prostate Cancer (SYNERGY)

Prostate Cancer

United States, Belgium, Canada, France, Germany, Hungary, Israel, Italy, Korea, Republic of, Netherlands, Spain, United Kingdom
Nimble Science Ltd.
IGY Life Sciences

Recruiting

Evaluation of the Microbiome in Multiple Sclerosis

Multiple Sclerosis

Canada
Active Life Scientific, Inc.
MCRA

Completed

Open Label Study Using OsteoProbe System (OP)

Adverse Effects in the Use of the OsteoProbe System

United States
SK Life Science, Inc.
PRA Health Sciences

Completed

Bioavailability and Food Effect Study of 3 Types of Carisbamate

Healthy Subjects

United States
Halucenex Life Sciences Inc.
KGK Science Inc.

Active, not recruiting

Investigating the Therapeutic Effects of Psilocybin in Treatment-Resistant Post-Traumatic Stress Disorder

Post Traumatic Stress Disorder | Treatment Resistant Disorders

Canada
Vigonvita Life Sciences

Recruiting

A Study of Deuremidevir Hydrobromide for Suspension in Chinese Infants Hospitalized With RSV

Respiratory Syncytial Virus Infection

China
Purpose Life Sciences

Not yet recruiting

Effect of Metformin in Reducing Fatigue in Long COVID in Adolescents (REVIVE)

Long COVID

Pakistan
Conceivable Life Sciences

Recruiting

Automation of Gamete Preparation, Intracytoplasmic Sperm Injection (ICSI), Embryo Culture, and Vitrification

Infertility

Mexico
Vigonvita Life Sciences

Recruiting

Study of the Safety, Tolerability, and Pharmacokinetics of LV232 Capsules in Chinese Healthy Volunteers

Healthy Subjects

China
Vigonvita Life Sciences

Completed

Safety and Pharmacokinetics of a Single Oral TPN171H in Healthy Elderly Subjects

Erectile Dysfunction

China
Vigonvita Life Sciences

Completed

A Study to Evaluate the Bioavailability, Food Effect and Pharmacokinetics of Deuremidevir Hydrobromide for Suspension

Healthy Subjects

China
Vigonvita Life Sciences

Completed

Efficacy and Safety Study of TPN171H Tablets in Erectile Dysfunction.

Erectile Dysfunction

China
Vigonvita Life Sciences

Completed

Safety and Pharmacokinetics Study of Multiple Ascending Doses of VV116 in Healthy Volunteers

Healthy Subjects

China
LG Life Sciences

Completed

Clinical Study to Evaluate the Correction of Wrinkles and Folds and Safety of YVOIRE Classic Versus Restylane in Nasolabial Fold Intradermal Injection

Temporary Correction of Wrinkles
LG Life Sciences

Completed

To Compare and Evaluate the Efficacy and Safety of Ganilever PFS(Prefilled Syringe) and Orgalutran®

Controlled Ovarian Stimulation

Korea, Republic of
LG Life Sciences

Completed

A Clinical Study to Evaluate the Efficacy and Safety of YVOIRE Classic Plus Versus YVOIRE Classic in Nasolabial Fold Injection

Wrinkles

3

Subscribe