Clinical Trials Sponsored by AdventHealth Translational Research Institute

Total 227 results

AdventHealth Translational Research Institute

Recruiting

REsearching Covid-19 Outcomes in Diabetes (RECODE) (RECODE)

Diabetes | Covid19

United States
AdventHealth Translational Research Institute

Recruiting

Dynamic in Vivo PET Imaging and ex Vivo Biopsies From Skeletal Muscle and Adipose Tissue to Investigate the Effects of Exercise on Insulin Resistance and Mitochondrial Energetics in Type 2 Diabetes (EXPET)

Type 2 Diabetes

United States
AdventHealth Translational Research Institute

Recruiting

Brown Adipose Tissue as a Therapeutic for the Metabolic and Cardiac Dysfunction With Senescence (BATSR) (BATSR)

Metabolic Diseases

United States
AdventHealth Translational Research Institute

Recruiting

The Role of Type 2 Diabetes on Skeletal Muscle Atrophy and Recovery Following Bed Rest in Older Adults (REST)

Type 2 Diabetes | Aging | Muscle Atrophy | Sedentary Behavior | Pre-diabetes

United States
AdventHealth Translational Research Institute

Active, not recruiting

Collection of Human Tissue Samples From the Neck Region for Characterization of Its Molecular and Biochemical Signatures (Human BAT)

Obesity

United States
AdventHealth Translational Research Institute

Active, not recruiting

Effect of AT-derived miRNA on the Biology and Insulin Sensitivity of Skeletal Muscle in Humans (miRNA)

Type 2 Diabetes Mellitus

United States
AdventHealth Translational Research Institute

Active, not recruiting

To Determine Tolerability to Glucagon Infusion in Obese Subjects (GIO)

Obesity

United States
AdventHealth Translational Research Institute

Active, not recruiting

Measurement of NAD+ Synthesis in Human Skeletal Muscle (NAD-flux)

Skeletal Muscle

United States
AdventHealth Translational Research Institute

Active, not recruiting

Study of the Pharmacologic Action of a GPR119 Agonist on Glucagon Counter-regulation During Insulin-induced Hypoglycemia in Type 1 Diabetes Mellitus (PHROG)

Diabetes Mellitus, Type 1

United States
AdventHealth Translational Research Institute

Active, not recruiting

Effects of MetAP2 Inhibition on Bioenergetics and Aging-associated Characteristics in Adipose Tissue in Healthy Participants (BIO-AGE)

Aging

United States
AdventHealth Translational Research Institute

Active, not recruiting

Muscle Insulin Resistance in Aging (Mirage)

Insulin Resistance | Sarcopenia

United States
AdventHealth Translational Research Institute

Active, not recruiting

Transcriptional and Epigenetic Program of PCOS Women (EPIC)

PCOS

United States
AdventHealth Translational Research Institute

Terminated

The Role of Microbiome Reprogramming on Liver Fat Accumulation (MILE)

NAFLD

United States
AdventHealth Translational Research Institute

Completed

Interactions of Human Gut Microbiota With Intestinal Sweet Taste Receptors (ISTAR-micro)

Obesity

United States
AdventHealth Translational Research Institute

Recruiting

Spatiotemporal Dimensions of Metabolism in Autochthonous Tumors of GBM Patients (GBM-FLUX2)

Glioblastoma Multiforme

United States
AdventHealth Translational Research Institute

Recruiting

Exercise to Boost Response to Checkpoint Blockade Immunotherapy (EX-BOOST)

Merkel Cell Carcinoma | Cutaneous Melanoma | Cutaneous Squamous Cell Carcinoma

United States
AdventHealth Translational Research Institute

Recruiting

Low-CArbohydrate Diet and SGLT2-INhibitOr to Achieve Moderate Ketosis in Healthy Volunteers (CASINO)

Ketones, Metabolism

United States
AdventHealth Translational Research Institute

Recruiting

Development of Novel Biomarkers for the Early Diagnosis of Type 1 Diabetes (HONEY)

Type 1 Diabetes

United States
AdventHealth Translational Research Institute

Recruiting

Magnetic Resonance & Optical Spectroscopy Validation

Validation Studies | Magnetic Resonance Spectroscopy

United States
AdventHealth Translational Research Institute

Active, not recruiting

Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes (RECOVER)

Type 2 Diabetes | Exercise | Muscular Atrophy | Sedentary Behavior | Pre-diabetes

United States
AdventHealth Translational Research Institute

Active, not recruiting

Microbiome-Mediated Gut Dysfunction in Non-Alcoholic Fatty Liver Disease (MODIFY)

Non-Alcoholic Fatty Liver Disease

United States
AdventHealth Translational Research Institute

Active, not recruiting

CharacterIzation of Adult Onset Autoimmune Diabetes (CIAO)

Diabetes

United States
AdventHealth Translational Research Institute

Active, not recruiting

Brown Adipose Tissue Pilot (BATSP)

Aging

United States
AdventHealth Translational Research Institute

Withdrawn

Impact of Orally Administered BPM31510 on Mitochondrial Energetics in Older Adults With Sarcopenia (COQ10)

Sarcopenia

United States
AdventHealth Translational Research Institute

Completed

Biomarkers of Liver Pathology in Patients With Presumed Non-Alcoholic Steatohepatitis Following Bariatric Surgery (BARI)

NASH - Nonalcoholic Steatohepatitis; NAFLD - Nonalcoholic Fatty Liver Disease

United States
AdventHealth Translational Research Institute

Completed

Effect of Nesiritide Infusion on Insulin Sensitivity in Healthy Obese Insulin Resistant Subjects (BNP3)

Diabetes

United States
AdventHealth Translational Research Institute

Recruiting

ImpaCt Of Shiftwork on METabolic Flexibility and Skeletal Muscle Clocks (COMET)

Metabolic Health

United States
AdventHealth Translational Research Institute

Recruiting

Development and Validation of Multi-nuclear Magnetic Resonance Imaging and Spectroscopy for Whole Body Human Applications (MRS VALIDATION)

Human Body Composition | Human Body Function

United States
AdventHealth Translational Research Institute

Active, not recruiting

Effect of Prolonged (72 Hour) Glucagon Administration on Energy Expenditure in Healthy Obese Subjects (GIO B)

Obesity

United States
AdventHealth Translational Research Institute

Active, not recruiting

Electrical Stimulation of Human Myocytes in Microgravity (microG)

Sarcopenia

United States
AdventHealth Translational Research Institute

Completed

The Influence of Glycemic Control and Obesity on Energy Balance and Metabolic Flexibility in Type 1 Diabetes (ACME)

Type 1 Diabetes

United States
AdventHealth Translational Research Institute

Completed

Collection of Gastrointestinal Tissue Samples for the Characterization and ex Vivo Functional Assessment of Chemoreceptors (ISTAR-T)

Diabetes

United States
AdventHealth Translational Research Institute

Completed

Effects of Glucagon Administration on Energy Expenditure (GLEE)

Obesity | Hyperglucagonemia

United States
AdventHealth Translational Research Institute
Takeda

Completed

Effect of Caloric Restriction on Fat Oxidation in Obese Men and Women (Magellan II) (MagellanII)

Metabolic Diseases | Obesity | Overweight

United States
AdventHealth Translational Research Institute
BioTherapeutics Inc.

Recruiting

Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity (ABA)

Pre Diabetes

United States
AdventHealth Translational Research Institute
Berg, LLC

Recruiting

AdventHealth Research Institute Non-Alcoholic Fatty Liver Disease Biobank and Registry (AVAIL) (AVAIL)

Non-Alcoholic Fatty Liver Disease

United States
AdventHealth Translational Research Institute
Arizona State University

Completed

Integrating Quantitative Energetics Determines the Microbiome's Contribution to Energy Balance

Obesity

United States
AdventHealth Translational Research Institute
Sanford-Burnham Medical Research Institute

Completed

Intestinal Sweet Taste Receptor Function and Adaptation to Dietary Sugars and Sweeteners (ISTAR)

Diabetes

United States
AdventHealth Translational Research Institute
Davos Alzheimer's Collaborative

Recruiting

Davos Alzheimer's Collaborative Study: Sequential Administration of Digital Testing To Screen For Cognitive Impairment Followed By Blood Based Biomarkers To Assist With Timely Detection And Accurate Diagnosis Of Alzheimer's Disease (DAC)

Alzheimer Disease

United States
AdventHealth Translational Research Institute
Wake Forest University

Recruiting

Investigating the Effects of Aerobic and Resistance Training in Vivo on Skeletal Muscle Metabolism in Vitro in Primary Human Muscle Cells (MoTrMyo) (MoTrMyo)

Physical Activity

United States
AdventHealth Translational Research Institute
American Diabetes Association

Active, not recruiting

Exercise Resistance in Type 2 Diabetes (RESIST)

Type 2 Diabetes

United States
AdventHealth Translational Research Institute
Sanford-Burnham Medical Research Institute

Completed

BNP Pharmacodynamics and Effects on Metabolism in Lean and Obese Subjects

Hypertension | Obesity | Cardiovascular Disease | Diabetes

United States
AdventHealth Translational Research Institute
Sanford-Burnham Medical Research Institute

Active, not recruiting

Epigenetic Regulation of Human Adipose Tissue Distribution (Eiffel 2)

Obesity

United States
AdventHealth Translational Research Institute
Sanford-Burnham Medical Research Institute

Completed

Maternal Adipose Tissue and Placental Dysfunction Programs the Fetus for Type 2 Diabetes (PlacentA-DM) (PlacentA-DM)

Obesity | Type 2 Diabetes

United States
AdventHealth Translational Research Institute
Takeda; Sanford-Burnham Medical Research Institute

Active, not recruiting

Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation (Columbus) (Columbus)

Obesity | Lipid Metabolism Disorders | Disorder of Lipid Storage and Metabolism | Metabolic Disorder

United States
AdventHealth Translational Research Institute
Sanford-Burnham Medical Research Institute; Florida Hospital Cardiovascular...

Active, not recruiting

Identifying Targets of Maladaptive Metabolic Responses in Heart Failure

Heart Failure

United States
AdventHealth Translational Research Institute
Boston University; Tufts University; Pennington Biomedical Research Center; Sanford-Burnham...

Active, not recruiting

Adipose Tissue and Polycystic Ovary Syndrome (PCOS)(EIFFEL) (EIFFEL)

Metabolic Diseases | Polycystic Ovary Syndrome | Overweight

United States
AdventHealth Translational Research Institute
AdventHealth; Sanford-Burnham Medical Research Institute; UCSF Benioff Children... and other collaborators

Completed

Uncovering the 'ORIGINS' of Diabetes (ORIGINS)

Type 2 Diabetes

United States
Translational Drug Development
Translational Genomics Research Institute

Active, not recruiting

Study Evaluating the Ketogenic Diet in Patients With Metastatic Pancreatic Cancer

Metastatic Pancreatic Ductal Adenocarcinoma

United States
Baylor Research Institute
Translational Genomics Research Institute

Recruiting

The TIOB - Collection of Patients' Biospecimens for Analysis of Immunological and Molecular Biomarkers. (TIOB)

Cancer

United States

Clinical Trials Sponsored by AdventHealth Translational Research Institute

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