Clinical Trials Sponsored by Aelix Therapeutics

Total 6295 results

Aelix Therapeutics

Completed

Safety and Immunogenicity Study of DNA.HTI, MVA.HTI and ChAdOx1.HTI in HIV-1-positive Patients (AELIX-002)

HIV

Spain
Aelix Therapeutics
Gilead Sciences

Completed

Safety, Tolerability and Immunogenicity of MVA.HTI and ChAdOx1.HTI With Vesatolimod in HIV-1 Positive Patients (AELIX-003)

HIV/AIDS

Spain
Aelis Farma

Completed

Study of [4-14C] AEF0117 Following a Single Oral Dose in Healthy Male Subjects

Marijuana Abuse

United States
Hospital Felix Bulnes

Completed

Efficacy of the "Start to Move" Protocol on Functionality, Delirium and Acquired Weakness in ICU (STM)

Mechanical Ventilation Complication | Intensive Care Unit Syndrome | Intensive Care Unit Acquired Weakness | Intensive Care Unit Delirium | Intensive Care Neuropathy

Chile
Helix Medical Systems

Terminated

Safety and Efficacy of Using CBUS™ System for Ultrasound Breast Imaging Designed for Breast Tumor Diagnosis

Breast Cancer

Israel
Aelis Farma
European Commission

Recruiting

Phase 1/2 Trial of AEF0217 in Participants With Down Syndrome (MDDS)

Down Syndrome

Spain
Telix International Pty Ltd

Recruiting

External Beam Therapy With Theranostic Radioligand Therapy for Oligometastatic Prostate Cancer (ProstACT TARGET)

Prostate Cancer

Australia
Telix International Pty Ltd

Completed

177Lu-DOTA-TLX591 Safety, Biodistribution and Dosimetry Study (ProstACTSelect)

Metastatic Prostate Cancer

Australia
Aelis Farma
European Commission

Completed

AEF0217 First-in-Human Phase I Study in 3 Parts (Single and Multiple Ascending Doses, and Food Effect) in Healthy Subjects. (AEF0217-101)

Safety, Tolerability, Pharmacokinetics of AEF0217

Spain
Telix International Pty Ltd

Recruiting

89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors

Soft Tissue Sarcoma | Cervical Cancer | Nasopharyngeal Carcinoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Glioblastoma Multiforme | Non Small Cell Lung Cancer | Cholangiocarcinoma | Epithelial Ovarian Cancer | Head and Neck Squamous Cell Carcinoma and other conditions

United States
Telix International Pty Ltd

Recruiting

131I-TLX-101 for Treatment of Newly Diagnosed Glioblastoma (IPAX-2) (IPAX-2)

Glioblastoma | Glioblastoma Multiforme | Neoplastic Disease

Australia, Austria, Netherlands, New Zealand
Helix BioPharma Corporation
Theradex

Recruiting

L-DOS47 Plus Doxorubicin in Advanced Pancreatic Cancer

Pancreas Cancer

United States
Telix International Pty Ltd

Completed

89Zr-TLX250 for PET/CT Imaging of ccRCC- ZIRCON Study (89ZR-TLX250)

Clear Cell Renal Cell Carcinoma

United Kingdom, United States, Australia, Turkey, Netherlands, Belgium, Canada, France
Telix International Pty Ltd

Completed

Evaluation of Safety, Biodistibution and Sensitivity/Specificity of PET/CT Imaging With 89Zr-TLX250 in Subjects With RCC (ZIRDAC-JP)

Carcinoma, Renal Cell | Clear Cell Renal Cell Carcinoma

Japan
Telix International Pty Ltd

Not yet recruiting

177Lu-DOTA-rosopatamab With Best Standard of Care (SoC) for the Second Line of Treatment for Metastatic Castrate-resistant Prostate Cancer, Which Expresses PSMA (PROSTACT)

Metastatic Prostate Cancer
Telix International Pty Ltd

Completed

131I-IPA and Concurrent XRT in Recurrent GBM (IPAX-1)

Glioblastoma Multiforme

Austria, Australia, Netherlands
Helix BioPharma Corporation
Theradex

Completed

A Dose Escalation Study of L-DOS47 in Recurrent or Metastatic Non-Squamous NSCLC

Non-Small Cell Lung Cancer

United States
Telix Pharmaceuticals (Innovations) Pty Limited

Available

89Zr-DFO-girentuximab Expanded Access Program (EAP)

Clear Cell Renal Cell Carcinoma

United States
Telix Pharmaceuticals (Innovations) Pty Limited

Completed

64Cu-TLX592 Phase I Safety, PK, Biodistribution and Dosimetry Study (CUPID Study) (CUPID)

Metastatic Prostate Cancer

Australia
Illumina, Inc.
Helix OpCo, LLC

Completed

Evaluation of the COVIDSeq Test in Nasal Swab and Saliva From a COVID-19 Asymptomatic Population

SARS-CoV-2

United States
Illumina, Inc.
Helix OpCo, LLC

Completed

Evaluation of the COVIDSeq Test in Saliva Specimens From COVID-19 Asymptomatic Illumina Personnel

SARS-CoV-2

United States
Helix BioPharma Corporation
KCR S.A.

Terminated

A Study of L-DOS47 in Combination With Vinorelbine/Cisplatin in Lung Adenocarcinoma

Lung Adenocarcinoma

Poland, Ukraine
Felix JF Herth

Unknown

Acute Dyspnea After Use of Non-invasive Ventilation in COPD and Emphysema (Deventilation Syndrome)

Obstructive Chronic Bronchitis
Parc de Salut Mar
Aelis Farma

Unknown

Clinical Validation of the Bordeaux Maze Test (BORMATE)

Healthy | Down Syndrome

Spain
BAMF Health
Telix International Pty Ltd

Recruiting

Total Body PET-CT Imaging of Prostate Cancer Using Illuccix

Metastatic Castration-resistant Prostate Cancer

United States
Helix BioPharma Corporation
Pharm-Olam International

Completed

A Phase I/II Open-Label, Non-Randomized Dose Escalation Study of Immunoconjugate L-DOS47

Non-Small Cell Lung Cancer

Poland
University Department of Geriatric Medicine FELIX...

Not yet recruiting

Combining Nutrition Supplementation With an Exercise Program in Elderly Malnourished Frail Patients After Hospital Stay

Frailty | Sarcopenia | Malnutrition; Protein
Memorial Sloan Kettering Cancer Center
Telix Pharmaceutical

Active, not recruiting

Evaluate The Utility Of 124I-cG250 for The Early Detection Of Response to Therapy In Patients With Metastatic Renal Cell Carcinoma

Renal Cancer

United States
Parc de Salut Mar
Aelis Farma; Starlab

Recruiting

Assessment of Neural Oscillations in Adult Subjects With Down Syndrome and Typically Developing Subjects in Resting State and While Conducting Cognitive Tasks (EEGDS)

Down Syndrome

Spain
M.D. Anderson Cancer Center
Telix Pharmaceuticals Limited

Active, not recruiting

Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment naïve Patients With Advanced Clear Cell RCC

Clear Cell Renal Cell Carcinoma | Advanced Cancer

United States
University Department of Geriatric Medicine FELIX...

Completed

Prevalence of Sarcopenia in Geriatric Patients

Sarcopenia

Switzerland
University Department of Geriatric Medicine FELIX...

Not yet recruiting

SARCOPEDIA - Sarcopenia Diagnostics in Aging Medicine (SARCOPEDIA)

Muscle Weakness | Frailty | Sarcopenia
University Department of Geriatric Medicine FELIX...

Completed

Power Centering for Seniors (PCS)

Healthy Aging | Mobility Limitation | Walking, Difficulty

Switzerland
Felix Ratjen

Completed

Tracking CF Lung Disease Through the Early Years: Utility of the LCI (LCITRACK)

Observational

Canada
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
Aelix Therapeutics

Completed

Study to Assess the Safety and Durability of Viral Control Beyond 24 Weeks of Analytical Treatment Interruption After the Administration of Candidate HIV-1 Vaccines DNA.HTI, MVA.HTI and ChAdOx1.HTI or Placebo in Early Treated HIV-1 Positive Individuals (ATI Extension of AELIX-002 Study)

HIV-1 Infection

Spain
Telix International Pty Ltd
Merck KGaA, Darmstadt, Germany

Recruiting

Combination of 177Lu-TLX250 and Peposertib in Patients With Carbonic Anhydrase IX -Expressing Solid Tumors

Advanced Solid Tumor | Solid Tumor, Adult | Advanced Renal Cell Carcinoma

Australia
Institut Cancerologie de l'Ouest
Telix Pharmaceutical; SIRIC ILIAD

Recruiting

Imaging Performance Assessment of 89Zirconium-labelled Girentuximab (89Zr-TLX250) PET-CT in Metastatic Triple Negative Breast Cancer Patients (OPALESCENCE)

Triple Negative Breast Cancer

France
Ranok Therapeutics (Hangzhou) Co., Ltd.

Recruiting

A Study of RNK05047 in Subjects With Advanced Solid Tumors/Diffuse Large B-cell Lymphoma (CHAMP-1)

Advanced Solid Tumor | DLBCL

United States
Aelis Farma
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Effect of AEF0117 on Treatment-seeking Patients With Cannabis Use Disorder (CUD) (SICA2)

Marijuana Abuse

United States
Aelis Farma
National Institute on Drug Abuse (NIDA)

Completed

Single Ascending Dose to Study the Safety, Tolerability, PK and PD Effects of AEF0117

Healthy Volunteers

United States
Aelis Farma
National Institute on Drug Abuse (NIDA)

Active, not recruiting

The Effect of Food on the Oral Bioavailability of AEF0117 in Healthy Volunteers

Marijuana Abuse

United States
Aelis Farma
National Institute on Drug Abuse (NIDA)

Completed

Multiple Ascending Dose to Study the Safety, Tolerability, PK and PD Effects of AEF0117

Healthy Volunteers

United States
Felix Mueller
University of Bern

Not yet recruiting

LSD Treatment for Persons With Alcohol Use Disorder (LYSTA)

Alcohol Use Disorder (AUD)

Switzerland
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by Albuminuria

Type 2 Diabetes Mellitus With Diabetic Nephropathy

United States
Akebia Therapeutics
Cyclerion Therapeutics

Completed

A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF) (CAPACITY-HFpEF)

Heart Failure With Preserved Ejection Fraction

United States, Canada
Felix Liebau
Karolinska University Hospital; Karolinska Institutet

Not yet recruiting

Nutrient Uptake During Continuous Enteral Feeding

Critical Illness
South Metropolitan Health Service
Telix Pharmaceuticals (Innovations) Pty Limited

Completed

Phase I Study to Evaluate the Diagnostic Performance of 89Zirconium Girentuximab PET in Urothelial Cancer Patients (ZiPUP)

Urothelial Carcinoma

Australia
Telix International Pty Ltd
Grand Pharmaceutical (China) Co., Ltd.

Recruiting

68Ga-PSMA-11 Efficacy in Detecting BCR Prostate Cancer in Chinese Patients

Prostate Cancer | Biochemical Recurrence of Malignant Neoplasm of Prostate | BCR Prostate Carcinoma

China
Telix International Pty Ltd
Grand Pharmaceutical (China) Co., Ltd.

Completed

Evaluation of 89Zr-TLX250 PET/CT in Chinese Patients With Indeterminate Renal Masses or Suspected Recurrent Renal Clear Cell Carcinoma (ZIRDOSE-CP)

Clear Cell Renal Cell Carcinoma | Recurrent Renal Cell Cancer | Suspected Recurrent Renal Clear Cell Carcinoma

China
CRISPR Therapeutics AG

Recruiting

A Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors

Clear Cell Renal Cell Carcinoma | Pancreatic Adenocarcinoma | Cervical Carcinoma | Malignant Pleural Mesothelioma | Esophageal Carcinoma

United States

Clinical Trials Sponsored by Aelix Therapeutics

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