Clinical Trials Sponsored by Allegro Ophthalmics, LLC

Total 57 results

Allegro Ophthalmics, LLC

Completed

A Safety And Efficacy Study Of Alg-1001 In Human Subjects With Symptomatic Focal Vitreomacular Adhesion

Symptomatic Focal Vitreomacular Adhesion

United States
Allegro Ophthalmics, LLC

Completed

A Safety And Efficacy Study Of ALG-1001 In Human Subjects With Wet Age-Related Macular Degeneration

Macular Degeneration

Mexico
Allegro Ophthalmics, LLC

Completed

A Clinical Trial Designed To Evaluate The Safety And Exploratory Efficacy Of 1.0 Mg Luminate® (Alg-1001) As A Treatment For Non-Exudative Macular Degeneration

Dry Age-related Macular Degeneration

United States
Allegro Ophthalmics, LLC

Withdrawn

Safety Study of ALG- 1001 to Treat Diabetic Macular Edema

Diabetic Macular Edema

Mexico
Allegro Ophthalmics, LLC
Duke University; Trial Runners, LLC

Completed

Phase 2 Randomized Clinical Trial of Luminate® as Compared to Avastin® in the Treatment of Diabetic Macular Edema

Diabetic Macular Edema

United States
Allegro Ophthalmics, LLC
Duke University; Trial Runners, LLC

Completed

A Clinical Trial Designed to Evaluate the Safety and Efficacy Study of Luminate® in Inducing PVD (Posterior Vitreous Detachment) in Non-Proliferative Diabetic Retinopathy

Non-Proliferative Diabetic Retinopathy

United States
Center for Ophthalmic and Vision Research, LLC

Completed

OC-01 (Varenicline) Nasal Spray and Dry Eye Signs and Symptoms in Daily Disposable Contact Lens Wearers

Dry Eye

United States
Center for Ophthalmic and Vision Research, LLC
Sun Pharmaceutical Industries Limited

Completed

CEQUA for Sjogren's Syndrome Dry Eye

Dry Eye | Dry Eye Syndromes | Sjogren's Syndrome

United States
HealthBeacon Plc
Modena Allergy & Asthma

Enrolling by invitation

A Pilot Study to Assess the Suitability of the HealthBeacon Injection Care Management System (ICMS) as a Remote Therapeutic Monitoring (RTM) Device

Respiratory Disease

United States
Immunogenics, LLC
National Institute of Allergy and Infectious Diseases (NIAID)

Active, not recruiting

Prospective, Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Symptomatic CD Patients

Celiac Disease

United States
The Center for Rheumatic Disease, Allergy, & Immunology
Grifols Therapeutics LLC

Completed

Efficacy of IgIv in Patients With IgG Subclass Deficiency and Recurrent Infections

Infections | IgG Deficiency

United States
AbViro LLC
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Study to Determine the Safety of AV-1, an Antibody Being Developed for Treatment of Dengue, in Healthy Volunteers

Healthy Volunteers

United States
National Institute of Allergy and Infectious Diseases...
Aviron LLC

Completed

Study of a Flu Vaccine in Children

Influenza

United States
ENT and Allergy Associates, LLP
Intersect ENT

Completed

The PIO (Propel In Office) III Study of In-office Placement of a Steroid-Eluting Implant Immediately Following Ethmoid Sinus Surgery

Chronic Sinusitis

United States
Allertein Therapeutics, LLC
Consortium of Food Allergy Research

Completed

Peanut Allergy Vaccine Study in Healthy and Peanut-allergic Adults

Hypersensitivity | Food Hypersensitivity | Peanut Hypersensitivity | Immediate Hypersensitivity

United States
BioFire Diagnostics, LLC
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Implementation of a Molecular Diagnostic for Pediatric Acute Gastroenteritis: The FilmArray GI Panel IMPACT Study (IMPACT)

Infectious Gastroenteritis

United States
Autoimmune Technologies, LLC
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety and Protective Efficacy of FF-3 Dry Powder in Healthy Subjects Infected With Influenza Challenge Strain

Influenza

United Kingdom
Trellis Bioscience LLC
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Study to Evaluate Safety and Activity of TRL345 in Healthy Volunteers

Healthy Volunteers

United States
Federal University of Health Science of Porto Alegre
Leonhardt Ventures LLC

Not yet recruiting

Whole-body Electrostimulation on Functional Mobility and Quality of Life in the Elderly

Aged
National Institute of Allergy and Infectious Diseases...
Merck Sharp & Dohme LLC

Completed

Evaluating the Safety, Tolerability, and Immunogenicity of a Tetravalent Dengue Vaccine (V180) in Healthy Adults Who Previously Received a Live-Attenuated Tetravalent Vaccine (TV003 or TV005)

Dengue

United States
National Institute of Allergy and Infectious Diseases...
The Emmes Company, LLC

Completed

Seasonal Influenza HA DNA With Trivalent Inactivated Vaccine (TIV) Administered ID or IM in Healthy Adults 18-70 Years

Influenza

United States
National Institute of Allergy and Infectious Diseases...
Merck Sharp & Dohme LLC

Completed

A Phase II, Comparative Study of Seroconversion of Single-Dose and Two-Dose Measles Vaccination in HIV-Infected and HIV-Uninfected Children: A Multicenter Trial of the Pediatric AIDS Clinical Trials Group

HIV Infections | Measles

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
The Emmes Company, LLC

Completed

Seasonal Influenza DNA Vaccine & Seasonal Influenza Trivalent Inactivated Vaccine (TIV) in Children & Adolescents

Influenza

United States
National Institute of Allergy and Infectious Diseases...
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes. (ELICIT)

HIV Infections | Cytomegalovirus | CMV

United States
National Institute of Allergy and Infectious Diseases...
The Emmes Company, LLC

Completed

Seasonal Influenza DNA Vaccine Prime With Trivalent Inactivated Vaccine (TIV) Boost Compared to TIV Alone

Influenza

United States
National Institute of Allergy and Infectious Diseases...
The Emmes Company, LLC

Completed

Evaluation of Influenza-Specific Immune Responses in Children and Adults During the 2010-2011 Influenza Season in the U.S.

Influenza

United States
Merck Sharp & Dohme LLC
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

A Pharmacokinetic Study of L-697,661 Alone and in Combination With Zidovudine

HIV Infections

United States
Boston Children's Hospital
National Institute of Allergy and Infectious Diseases (NIAID); Sanofi; Merck... and other collaborators

Recruiting

Investigating Dupilumab's Effect in Asthma by Genotype (IDEA)

Asthma

United States
Federal University of Health Science of Porto Alegre
Irmandade Santa Casa de Misericórdia de Porto Alegre; Leonhardt Ventures LLC

Not yet recruiting

Effects of Electrical Nervous Stimulation Transcutaneous in Hypertensive Patients

Hypertension | Hypertension,Essential
Federal University of Health Science of Porto Alegre
Irmandade Santa Casa de Misericórdia de Porto Alegre; Leonhardt Ventures LLC

Unknown

Bioeletric Stimulation in Patients With Chronic Kidney Failure

Chronic Kidney Disease Stage 5 | Electric Stimulation
Federal University of Health Science of Porto Alegre
Irmandade Santa Casa de Misericórdia de Porto Alegre; Leonhardt Ventures LLC

Not yet recruiting

Effects of Bioelectric Stimulation in Patients With Non-Dialysis Dependent Chronic Kidney Disease

Renal Insufficiency, Chronic | Electric Stimulation
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp...

Completed

Reversing Tissue Fibrosis to Improve Immune Reconstitution in HIV

HIV Infections | HIV Infection

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); Exegi Pharma...

Completed

Effects of the Probiotic Visbiome Extra Strength on Gut Microbiome & Immune Activation Markers

HIV-1 Infection

United States, Puerto Rico
Merck Sharp & Dohme LLC
National Institute of Allergy and Infectious Diseases (NIAID); BioProtection...

Completed

Safety and Immunogenicity of Prime-Boost Vesicular Stomatitis Virus (VSV) Ebola Vaccine in Healthy Adults (V920-002)

Ebola Viruses
Merck Sharp & Dohme LLC
National Institute of Allergy and Infectious Diseases (NIAID); HIV Vaccine...

Completed

A Worldwide, Phase I, Dose-Escalating Study of a 3-Dose Regimen of the MRKAd5 (Clade B) Vaccine in Healthy Adults (V520-018)

HIV Infections | HIV-1
Rhonda Brand
National Institute of Allergy and Infectious Diseases (NIAID); Intrucept Biomedicine...

Terminated

Griffithsin-based Rectal Microbicide for PREvention of Viral ENTry (PREVENT) (PREVENT)

HIV Prevention

United States
BioFire Defense LLC
National Institute of Allergy and Infectious Diseases (NIAID); United States...

Active, not recruiting

Clinical Evaluation of the FilmArray® Global Fever (GF) Panel

Fever

United States, Uganda, Thailand, Tanzania, Cambodia, Georgia, Ghana, Honduras, Kenya, Peru
National Institute of Allergy and Infectious Diseases...
The Emmes Company, LLC; US Military HIV Research Program

Completed

Clinical Trial of Ebola Vaccines cAd3-EBO, cAd3-EBOZ and MVA-EbolaZ in Healthy Adults in Uganda

Hemorrhagic Fever, Ebola

Uganda
National Institute of Allergy and Infectious Diseases...
Merck Sharp & Dohme LLC; Adult AIDS Clinical Trials Group

Completed

Live Zoster Vaccine in HIV-Infected Adults on Antiretroviral Therapy

HIV Infections | Herpes Zoster

United States
National Institute of Allergy and Infectious Diseases...
Auro Vaccines LLC

Completed

Therapeutic Vaccine for HIV

HIV | Therapeutic Vaccine

United States
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Terminated

MK-0518 Intensification And HDAC Inhibition In Depletion Of Resting CD4+ T Cell HIV Infection

HIV Infections

United States
The Wistar Institute
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Unknown

Reducing Proviral HIV DNA With Interferon-a (BEAT-HIV)

HIV/AIDS | HIV

United States
MedImmune LLC
National Institute of Allergy and Infectious Diseases (NIAID); Antibacterial... and other collaborators

Completed

Effort to Prevent Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa in Mechanically Ventilated Subjects (EVADE)

Pseudomonas Aeruginosa

Spain, United States, Belgium, France, Hungary, United Kingdom, Israel, Austria, Portugal, Greece, Czechia, Turkey, Croatia, Ireland
Kirby Institute
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

Attenuation of D-dimer Using Vorapaxar to Target Inflammatory and Coagulation Endpoints (ADVICE)

HIV

Australia, United States
MedImmune LLC
National Institute of Allergy and Infectious Diseases (NIAID); Innovative Medicines... and other collaborators

Completed

Study of the Efficacy and Safety of MEDI4893 (SAATELLITE)

Staphylococcus Aureus Pneumonia

Spain, Belgium, United States, France, Germany, Czechia, Greece, Switzerland, Hungary, Portugal
Robert L. Murphy
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

Therapeutic Intensification Plus Immunomodulation to Decrease the HIV-1 Viral Reservoir (EraMune02)

HIV Infection

United States
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

The Effect of Vorinostat on HIV RNA Expression in the Resting CD4+ T Cells of HIV+ Pts on Stable ART

HIV-1 Infection

United States
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

A5288/MULTI-OCTAVE: Management Using Latest Technologies to Optimize Combination Therapy After Viral Failure (MULTI-OCTAVE)

HIV-1 Infection

Kenya, Brazil, South Africa, Uganda, Zimbabwe, India, Malawi, Haiti, Thailand, Peru
US Department of Veterans Affairs
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp...

Completed

Shingles Prevention Study (SPS)

Herpes Zoster | Postherpetic Neuralgia

United States
Luis Montaner
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Unknown

Peg-Interferon Alpha 2b Combined With Two Intravenous Broadly HIV-1 Neutralizing Antibodies 3BNC117 and 10-1074 (BEAT-2) (BEAT-2)

HIV/AIDS | HIV | HIV-1 Infection

United States

Clinical Trials Sponsored by Allegro Ophthalmics, LLC

Sponsors and Collaborators

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