Clinical Trials Sponsored by Andre Denault

Total 325 results

Andre Denault
Organon; Canadian Anesthesiologists' Society; Heart and stoke fondation of Quebec

Completed

Milrinone Inhaled in Cardiac Surgery

Coronary Artery Disease | Hypertension, Pulmonary | Valvular Stenosis | Valvular Insufficiency

Canada
Andre Nazac

Completed

Feasibility Study of Accelerated Preoperative Radiotherapy for Early Breast Cancer

Breast Cancer

Belgium
Denali Therapeutics Inc.

Recruiting

A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II) (COMPASS)

Mucopolysaccharidosis II

United States, Spain, United Kingdom, Czechia, France, Canada, Italy, Belgium, Netherlands, Germany, Argentina, Sweden, Turkey, Colombia
Denali Therapeutics Inc.

Active, not recruiting

A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States, Netherlands
Denali Therapeutics Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL343 in Healthy Volunteers

Healthy Volunteers

Netherlands
Denali Therapeutics Inc.

Completed

Study to Evaluate DNL201 in Subjects With Parkinson's Disease

Parkinson Disease

United States
Andrew Gvozdanovic

Unknown

Digitisation of the Timed Up and Go Test for the General Public

Mobility Limitation
S. Andrea Hospital

Unknown

Safety Study of Dabigatran in CADASIL (SONICA)

CADASIL

Italy
S. Andrea Hospital

Unknown

Safety and Tolerability of Interferon-Beta-1a and Estroprogestins Association in MS Patients

Multiple Sclerosis

Italy
DePaul University

Not yet recruiting

Emotion, Aging, and Decision Making

Aging | Emotions | Health Behavior | Motivation | Social Behavior

United States
S. Andrea Hospital

Recruiting

Bacille Calmette-Guérin (BCG) Vaccine In Radiologically Isolated Syndrome (RIS)

Multiple Sclerosis

Italy
S. Andrea Hospital

Completed

Barriers and Breakthroughs in IMPlementing Split Regimen OVEr Single Dose (IMPROVES)

Colonoscopy: Bowel Preparation
S. Andrea Hospital

Terminated

Gene Expression in MS Patients Before and During Treatment With Interferon-beta

Multiple Sclerosis

Italy
S. Andrea Hospital

Unknown

Effect of Lactobacillus Brevis CD2 in Prevention of Radio-chemotherapy Induced Oral Mucositis in Head and Neck Cancer

Mucositis

Italy
S. Andrea Hospital

Unknown

Riluzole in Patients With Spinocerebellar Ataxia Type 7

SCA7

Italy
S. Andrea Hospital

Completed

Body Cooling During Carotid Endarterectomy: No-profit, Open, Mono-centric, Feasibility Study

Stroke | Carotid Artery Plaque | Carotid Artery Diseases | Hypothermia | Cerebrovascular Accident | Carotid Artery Stenosis

Italy
S. Andrea Hospital

Terminated

Hydroxyurea in Primary Progressive Multiple Sclerosis

Multiple Sclerosis

Italy
S. Andrea Hospital

Completed

Effect of Riluzole as a Symptomatic Approach in Patients With Chronic Cerebellar Ataxia

Multiple Sclerosis | Cerebellar Ataxia | Hereditary Ataxia

Italy
Denali Therapeutics Inc.

Recruiting

A Phase 1, Open-label Study of the Absorption, Metabolism, and Excretion of [14C]-DNL343 Following a Single Oral Dose in Healthy Male Participants

Healthy Volunteers

United States
Denali Therapeutics Inc.

Recruiting

A Study of Tividenofusp Alfa (DNL310) in Pediatric Participants With Hunter Syndrome

Mucopolysaccharidosis II

United States, Netherlands, Canada, United Kingdom
Denali Therapeutics Inc.

Enrolling by invitation

An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007

Mucopolysaccharidosis II

United States, Canada, Belgium, Czechia, Netherlands
Denali Therapeutics Inc.

Completed

Study to Evaluate DNL747 in Subjects With Alzheimer's Disease

Alzheimer Disease

United States, Netherlands
Karla Andrea Arias Varela

Completed

Treatment of Osteoarthrosis of the Knee With Platelet Rich Plasma, Comparative Study With Hyaluronic Acid

Osteoarthritis

Costa Rica
RENAULT Patrick Aldo

Completed

Feasibility of Immunotherapy Administration to Patients With Bronchial Cancer in a Hospital-at- Home Setting (ImHADom) (ImHADom)

Bronchial Cancer

France
Karl-Andre Wian

Terminated

Cerebral Oxygenation in Septic Patients Using Vasopressors - the Conscious Study (CONSCIOUS)

Septic Shock

Norway
Universidad Nacional Andres Bello
Hospital de Simulación, Universidad Andres Bello

Completed

Virtual Clinical Simulation for Training Amongst Undergraduate Medical Students: A Pilot Randomised Trial (VIRTUE-Pilot)

Medical Education

Chile
Denali Therapeutics Inc.
Takeda

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)

Frontotemporal Dementia

Spain, Turkey, France, Belgium, Netherlands, Portugal, Italy, Colombia, Czechia, Brazil, United Kingdom, Serbia
Sanofi
Denali Therapeutics Inc.

Terminated

Study to Evaluate DNL747 in Subjects With Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis

United States, Netherlands
Andrei Iagaru

Recruiting

99mTc Sestamibi SPECT/CT vs 18F Fluorocholine PET/CT (18FCH)

Parathyroid Adenoma

United States
Andrei Iagaru

Not yet recruiting

Study Evaluating Zr-Panitumumab for Assessment of Suspected Metastatic Lesions on 18F-FDG-PET/CT in Head and Neck Squamous Cell Carcinoma

Head-and-neck Squamous Cell Carcinoma

United States
Andrei Iagaru

Completed

Gallium Ga 68 DOTA-NeoBOMB1 and Gallium Ga 68 PSMA-R2 PET/MRI in Diagnosing Participants With Recurrent Prostate Cancer

Prostate Adenocarcinoma | Recurrent Prostate Carcinoma | PSA Progression

United States
Universidad Nacional Andres Bello

Completed

Clinical Performance of Two Bulk-Fill Composite of Posterior Restorations

Caries, Dental | Post Dental Restoration

Chile
Andrei Iagaru

No longer available

F18 DCFPyL PET/CT in Imaging Participants With Recurrent Prostate Cancer

Prostate Adenocarcinoma | Recurrent Prostate Carcinoma | PSA Progression | PSA Level Greater Than or Equal to Two | PSA Level Greater Than 0.2

United States
Universidad Nacional Andres Bello

Completed

Behavioral Therapy and Self-care vs Thermoformed Occlusal Splints in the Treatment of Masticatory Muscles Pain

Myalgia of Mastication Muscle

Chile
Universidad Nacional Andres Bello

Completed

Effects of Mandibular Exercises Effect on Pain Perception and Sensitivity in Mandibular Myofascial Pain

Temporomandibular Disorders
Andrei Iagaru

No longer available

68Ga DOTA-TATE PET/CT in Somatostatin Receptor Positive Tumors

Carcinoid Tumors | Islet Cell (Pancreatic NET) | Other Neuroendocrine Tumors

United States
Denali Therapeutics Inc.

Recruiting

Study of DNL126 in Pediatric Participants With Mucopolysaccharidosis Type IIIA (Sanfilippo Syndrome Type A)

Mucopolysaccharidosis Type IIIA

United States
Denali Therapeutics Inc.

Completed

A Study of Potential Treatment-Responsive Biomarkers and Clinical Outcomes in Hunter Syndrome

Mucopolysaccharidosis II

United Kingdom, United States, Italy, Netherlands
Denali Therapeutics Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL151 in Healthy Volunteers

Healthy Volunteers

Netherlands
Denali Therapeutics Inc.

Completed

A Study to Evaluate the Bioavailability and Safety of DNL343 in Healthy Volunteers

Healthy Volunteers

New Zealand
Denali Therapeutics Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL201 in Healthy Volunteers

Healthy Volunteers

United States
Andrew Picel

Recruiting

Genicular Artery Embolization (GAE) for Osteoarthritic Knee Pain

Knee Osteoarthritis | Knee Arthritis | Arterial Occlusion | Knee Pain Chronic | Knee Pain Swelling

United States
Andrei Iagaru

Completed

68Ga-RM2 PET/CT in Detecting Regional Nodal and Distant Metastases in Patients With Intermediate or High-Risk Prostate Cancer

Stage II Prostate Adenocarcinoma | Stage III Prostate Adenocarcinoma | Stage IV Prostate Adenocarcinoma

United States
Andrew Eisenberger

Terminated

Convalescent Plasma for Early Treatment of COVID-19

COVID-19 | SARS-CoV 2

Brazil
Andrei Iagaru

Completed

68Ga-PSMA PET/CT in Detecting Prostate Cancer Recurrence in Patients With Elevated PSA After Initial Treatment

Prostate Adenocarcinoma | Recurrent Prostate Carcinoma | PSA Failure

United States
Andrew Picel

Withdrawn

Prostatic Artery Embolization for the Treatment of Symptomatic Benign Prostatic Hyperplasia (BPH)

Lower Urinary Tract Symptoms | Benign Prostatic Hyperplasia

United States
Andrew Eisenberger

Completed

Study of Chimeric Fibril-Reactive Monoclonal Antibody 11-1F4 in Patients With AL Amyloidosis

Amyloidosis

United States
Andrea Cimolato

Recruiting

Improving Grasp Function in People With Sensorimotor Impairments by Combining Electrical Stimulation With a Robotic Hand Orthosis (SENSIBLE-EXO)

Stroke | Traumatic Brain Injury | Spinal Cord Injuries

Switzerland
Universidad Nacional Andres Bello

Completed

Self-management and Home Exercises for the Treatment of Masticatory Muscle Pain. A Clinical Trial

Myalgia of Mastication Muscle
Andrei Iagaru

Completed

68Ga-RM2 PET/MRI in Biochemically Recurrent Prostate Cancer

Prostate Adenocarcinoma

United States

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