Clinical Trials Sponsored by Aphton

Total 74 results

Aphios

Not yet recruiting

Study of APH-1105 in Patients With Mild to Moderate Alzheimer's Disease

Dementia | Alzheimer Disease 1 | Alzheimer Disease 2 | Alzheimer Disease 3
Aphios

Not yet recruiting

Exploratory Dose Ranging Study Assessing APH-1501 for the Treatment of Opioid Addiction

Addiction | Opioid Dependence | Opioid Withdrawal
SpotOn Therapeutics Ltd.

Suspended

Spoton Trial Evaluating the Efficacy on BAlance Disorder sYmptoms (STEADY) (STEADY)

Balance Disorders

Israel
SpotOn Therapeutics Ltd.

Suspended

Treatment of Balance Disorders in Parkinson's Patients Using SpotOn Balance Glasses

Parkinson Disease

Israel
Aston University

Not yet recruiting

Photobiomodulation With REd vs BluE Light (REBEL)

Dry Eye Syndromes | Meibomian Gland Dysfunction | Blepharitis

United Kingdom
Aston University

Recruiting

Intense Regulated Pulsed Light Vs Standard of Care for the Treatment of Meibomian Gland Dysfunction

Meibomian Gland Dysfunction

Canada
Aston University

Completed

Dry Eye Treatment With Artificial Tears

Dry Eye

United Kingdom
Aston University

Completed

EyeBag Effectiveness in Meibomian Gland Dysfunction (MGD)

Meibomian Gland Dysfunction

United Kingdom
Aston University

Not yet recruiting

Protecting the Eyes of Gamers With Lubricating Eyedrops (PROTEGE)

Dry Eye Syndromes | Computer Vision Syndrome
Aston University

Recruiting

Mechanisms of Light-based Therapies for Dry Eye Disease (MOLT)

Dry Eye Syndromes | Meibomian Gland Dysfunction

United Kingdom
Aston University

Recruiting

Assessing the Impact of Tixel Treatment of Periorbital Wrinkles on Dry Eye Symptoms and Signs

Dry Eye | Dry Eye Syndromes

United Kingdom
Aston University

Enrolling by invitation

Assessment of Visual Function and Optics in Intraocular Lenses

Cataract

United Kingdom
Aston University

Completed

Using Models' Facial Expressions to Enhance Healthy Eating Behaviour in Children

Eating Behavior

United Kingdom
Aston University

Completed

Relationship Between Central Corneal Thickness and Intraocular Pressure Measures Instruments.

Ocular Hypertension | Glaucoma | Keratoconus | Glaucoma, Open Angle

United Kingdom
Aston Sci. Inc.

Recruiting

Therapeutic Cancer Vaccine (AST-301, pNGVL3-hICD) in Patients With Breast Cancer (Cornerstone001)

Breast Cancer

United States, Taiwan
Medtronic Endovascular
Sapheon, Inc.

Completed

VenaSeal Sapheon Closure System Pivotal Study (VeClose) (VeClose)

Great Saphenous Vein (GSV) With Venous Reflux Disease

United States
Aston Sci. Inc.

Recruiting

Therapeutic Cancer Vaccine (AST-301, pNGVL3-hICD) in Gastric Cancer (Conerstone3)

Gastric Cancer

Taiwan
Aston University
NuVision

Completed

Dry Eye OmniLenz Application of Omnigen Research Study (DOORS)

Dry Eye

United Kingdom
Aston Sci. Inc.

Active, not recruiting

AST-021p Study in Advanced Solid Tumors

Advanced Cancer

Korea, Republic of
Aston Sci. Inc.

Not yet recruiting

Adjuvant Therapeutic Cancer Vaccine (AST-201, pUMVC3-hIGFBP-2) in Patients With Advanced Ovarian Cancer (Cornerstone4)

Advanced Ovarian Cancer

United States
Aston University
TearLab Corporation

Completed

Tear Osmolarity Clinical Utility in Dry Eye Disease

Dry Eye

United Kingdom
Alcon Research
Aston University

Completed

Pre-Lens Tear Film Performance of Silicone Hydrogel Daily Disposable Contact Lenses

Myopia
Nottingham Trent University
Aston University

Completed

β-alanine Supplementation in Adults With Overweight/Obesity (BASA-O)

Hyperglycemia | Overweight or Obesity | Prediabetes

United Kingdom
Meir Medical Center
SpotOn Therapeutics Ltd.

Completed

Study to Assess the Efficacy and Safety of SpotOn Specs™ for the Treatment of Chronic Dizziness

Chronic Dizziness

Israel
University Medical Center Groningen
Akston Biosciences Corporation

Completed

Anti-COVID19 AKS-452 Fusion Protein Vaccine - ACT Study (ACT)

Covid19

Netherlands
Aston University
College of Optometrists

Completed

Effect of Peripheral Defocus on Axial Growth in Hyperopes

Hyperopia | Amblyopia | Anisohyperopia

United Kingdom
Aston University
University of Worcester

Completed

Non-Pharmaceutical Treatment of Seasonal Allergic Conjunctivitis

Hypersensitivity

United Kingdom
Alton Melton
The Cleveland Clinic

Active, not recruiting

Boiled Peanut Oral Immunotherapy (BPOIT)

Peanut Hypersensitivity

United States
CIBA VISION
Aston University

Completed

Daily Disposable Contact Lens Tear Film Study

Myopia

United Kingdom
Ahon Pharmaceutical Co., Ltd.

Recruiting

Phase 1 Hepatic Insufficiency Trial of Methoxyethyl Etomidate Hydrochloride

Hepatic Insufficiency

China
Aston University
Manchester Royal Eye Hospital

Completed

Independent Prescribing Optometrists in Acute Ophthalmic Services

Eye Abnormalities

United Kingdom
Aston University
The Dunhill Medical Trust

Completed

Colour Contrast Sensitivity for the Early Detection of Wet Age-related Macular Degereration (CEDAR) (CEDAR)

Age Related Macular Degeneration

United Kingdom
Dr. Anton Hommer

Completed

An Open, Non-randomized Pilot Study on the Effect of Preservative Free Tafluprost (Saflutan® Augentropfen) in Patients With Ocular Hypertension or Primary Open Angle Glaucoma With an Uncontrolled Intraocular Pressure of 30 mmHg and More

Primary Open Angle Glaucoma | Ocular Hypertension

Austria
South Warwickshire NHS Foundation Trust
Aston University

Unknown

Polarization Perception in Health and Disease. Testing a New Sight Test (TaNSiT)

Diabetic Retinopathy | Cataract | Age Related Macular Degeneration | Macular Disease | Pseudophakia | Retinal Disease

United Kingdom
Patton Medical Devices
Medstar Health Research Institute; Valeritas, Inc.

Completed

A Prospective, Randomized, Parallel Crossover Study Demonstrating Subject Wearability and Usability of the I-Port Injection Port

Type 1 Diabetes | Type 2 Diabetes

United States
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c in Combination With Fluvestrant ± Goseraline Versus Placebo Combined With Fulvestrant ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Ahon Pharmaceutical Co., Ltd.

Recruiting

This is a Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of FCN-437c Versus Placebo in Combination With Letrozole or Anastrozole ± Goserelin in Women With HR+ and HER2- Advanced Breast Cancer.

Advanced Breast Cancer | Female Breast Cancer

China
Ahon Pharmaceutical Co., Ltd.

Recruiting

A Trial to Evaluate the Efficacy and Safety of Methoxyetomidate Hydrochloride for Injection (ET-26) for the Induction of General Anesthesia in Elective Surgery Subjects

Anesthesia Induction

China
Ahon Pharmaceutical Co., Ltd.

Completed

Clinical Study on Pharmacokinetics of FCN-437c Capsule and Its Effect on QT Interval in Healthy Subjects

Advanced Breast Cancer

China
Nottingham University Hospitals NHS Trust
Aston University

Completed

Evaluation of Self-management Education in First Time Hearing Aid Users

Hearing Loss
University of Kansas Medical Center
Paul J. Patton Trust

Completed

Pharmacogenomic Study in Patients of Lung, Colorectal and Head/Neck Cancers Receiving Chemotherapy

Head and Neck Cancer | Colorectal Cancer | Lung Cancer

United States
Overseas Pharmaceuticals, Ltd.
Beijing Capton Pharmaceutical Technology Development Co., LTD

Not yet recruiting

An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.

Epilepsy

China
Aston University
Sandwell & West Birmingham Hospitals NHS Trust

Withdrawn

Development of an IT Tool Able to Identify Ocular Conditions

Eye Diseases
Aston University
University Hospital Birmingham NHS Foundation Trust

Withdrawn

CRT Improved Clinical Response UK Trial (CRICKET)

Cardiac Failure
Aston University
University Hospital Birmingham NHS Foundation Trust

Completed

Use of Low-dose Zolpidem in Parkinson's Disease

Parkinson Disease

United Kingdom
Aston University
National Pollen and Aerobiology Unit, Worcester

Completed

The Role of Daily Disposable Contact Lenses in Ocular Allergy

Grass Pollen Ocular Allergy

United Kingdom
Örebro University, Sweden
Aston University; Region Örebro County; VHIR

Enrolling by invitation

Early Signs of Parkinsons Disease in IBS

Parkinson Disease | Irritable Bowel Syndrome

Sweden
Heather Patton
American College of Gastroenterology

Completed

A Study of Siliphos in Adults With Non-alcoholic Steatohepatitis (NASH)

Fatty Liver

United States
Aston University
Birmingham Women's and Children's NHS Foundation Trust

Recruiting

Efficacy of Lenses in Abolishing Photoparoxysmal Responses (PPRs)

Reflex Epilepsy, Photosensitive | Eyeglasses

United Kingdom
KU Leuven
VU University of Amsterdam; Anton De Kom University

Completed

SunRISe Study - Stroke Rehabilitation In Suriname (SunRISe)

Stroke

Suriname

Clinical Trials Sponsored by Aphton

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