Clinical Trials Sponsored by Arbutus Biopharma Corporation

Total 105 results

Arbutus Biopharma Corporation

Not yet recruiting

Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection

Hepatitis B, Chronic
Arbutus Biopharma Corporation

Active, not recruiting

Open-Label Study of AB-729, Nucleos(t)Ide Analogue and Pegylated Interferon Alfa-2a in Subjects With Chronic Hepatitis B Infection

Chronic Hepatitis b

United States, Korea, Republic of, Hong Kong, Taiwan, Australia, Moldova, Republic of, Ukraine
Arbutus Biopharma Corporation

Completed

Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Intravenous TKM-080301 in Subjects With Advanced Hepatocellular Carcinoma

Hepatocellular Carcinoma | Hepatoma | Liver Cancer, Adult | Liver Cell Carcinoma, Adult

United States, Taiwan, Singapore, China, Canada, Korea, Republic of
Arbutus Biopharma Corporation

Terminated

Safety, Tolerability, and Pharmacokinetics of AB-836 in Healthy Subjects and Subjects With Chronic HBV Infection

Chronic Hepatitis

Korea, Republic of, Hong Kong, Thailand, Canada, Australia, Moldova, Republic of, New Zealand, Ukraine
Arbutus Biopharma Corporation

Completed

Study of ARB-001467 in Subjects With Chronic HBV Infection Receiving Nucleos(t)Ide Analogue Therapy

Hepatitis B, Chronic

Australia, New Zealand
Arbutus Biopharma Corporation

Terminated

Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Liposomal siRNA in Subjects With High Cholesterol

Hypercholesterolemia

United States
Arbutus Biopharma Corporation

Not yet recruiting

Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)

Long Term Follow-up

Hong Kong, Australia, Taiwan, United Kingdom
Arbutus Biopharma Corporation

Recruiting

Safety, Tolerability, PK & PD of AB-101 Following Oral Administration in Healthy and CHB Subjects.

Chronic Hepatitis b

New Zealand
Arbutus Biopharma Corporation

Completed

A Dose Finding Study of TKM-080301 Infusion in Neuroendocrine Tumors (NET) and Adrenocortical Carcinoma (ACC) Patients

Cancer | Neuroendocrine Tumors | Adrenocortical Carcinoma | ACC | NET

United States
Assembly Biosciences
Arbutus Biopharma Corporation

Terminated

A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infection

Chronic Hepatitis B

Australia, Canada, Bulgaria, New Zealand
University of Maryland, Baltimore
Arbutus Biopharma Corporation

Not yet recruiting

Intrahepatic and Peripheral Responses to Imdusiran (AB-729) in Chronic Hepatitis B (i-LIVER)

Chronic Hepatitis B
Arbutus Biopharma Corporation
United States Department of Defense

Terminated

Safety, Tolerability and Pharmacokinetic First in Human (FIH) Study of Intravenous (IV) TKM-100201 Infusion

Ebola Virus Infection

United States
Arbutus Biopharma Corporation
United States Department of Defense

Terminated

Safety, Tolerability and Pharmacokinetic First in Human (FIH) Study for Intravenous (IV) TKM-100802

Ebola Virus Infection

United States
Helix BioPharma Corporation
Theradex

Recruiting

L-DOS47 Plus Doxorubicin in Advanced Pancreatic Cancer

Pancreas Cancer

United States
Helix BioPharma Corporation
Theradex

Completed

A Dose Escalation Study of L-DOS47 in Recurrent or Metastatic Non-Squamous NSCLC

Non-Small Cell Lung Cancer

United States
TSH Biopharm Corporation Limited

Terminated

Phase 3 Study to Evaluate the Efficacy and Safety of Droxidopa on Orthostatic Hypotension Treatment in Hemodialysis Patients (OH)

Orthostatic Hypotension

Taiwan
TSH Biopharm Corporation Limited

Completed

ADDM Study - Amtrel and Co-Diovan in Type 2 Diabetes Mellitus Hypertension Patients With Microalbuminuria

Hypertension | Diabetes Mellitus, Type 2 | Albuminuria

Taiwan
BioFirst Corporation
ABVC BioPharma, Inc

Suspended

Clinical Investigation of the Safety and Effectiveness of the ABV-1701 Ocular Endotamponade (OE)

Retinal Detachment

Thailand, Australia
Helix BioPharma Corporation
KCR S.A.

Terminated

A Study of L-DOS47 in Combination With Vinorelbine/Cisplatin in Lung Adenocarcinoma

Lung Adenocarcinoma

Poland, Ukraine
TSH Biopharm Corporation Limited

Completed

Corever in the Treatment of Hypertension

Hypertension

Taiwan
TSH Biopharm Corporation Limited

Completed

DMTA07 Combine With Amlodipine Treatment in Patients With Hypertension

Hypertension

Taiwan
TSH Biopharm Corporation Limited

Recruiting

A Study to Assess Mitomic Prostate Test for Prostate Cancer Screening

Prostate Cancer

Taiwan
TSH Biopharm Corporation Limited

Completed

Propafenone in the Treatment of Atrial Fibrillation

Atrial Fibrillation

Taiwan
TSH Biopharm Corporation Limited

Completed

A TSHRN1201 Sub-study-To Evaluate the Effects of add-on Ranolazine on Exercise Tolerance and Angina Frequency

Angina

Taiwan
TSH Biopharm Corporation Limited

Completed

Extended-Release RANCAD in the Patients With Stable Angina Pectoris

Stable Angina Pectoris

Taiwan
TSH Biopharm Corporation Limited

Completed

PMS Study of Amlodipine/Valsartan for the Treatment of Hypertension

Essential Hypertension

Taiwan
Green Cross Corporation

Completed

A Study of MG1111 in Healthy Children

Healthy Children

Korea, Republic of
Green Cross Corporation

Completed

Safety and Efficacy of IGIV 10% in Patients With Autoimmune Encephalitis:

Autoimmune Encephalitis

Korea, Republic of
Helix BioPharma Corporation
Pharm-Olam International

Completed

A Phase I/II Open-Label, Non-Randomized Dose Escalation Study of Immunoconjugate L-DOS47

Non-Small Cell Lung Cancer

Poland
Green Cross Corporation

Unknown

Study to Investigate the Safety and Efficacy of GC3107 (BCG Vaccine) in Healthy Adults

Tuberculosis

Korea, Republic of
Green Cross Corporation

Unknown

A Study to Evaluate the Efficacy and Safety of GC3110A in Healthy Infants From 6 Months to 35 Months of Age

Influenza Vaccine

Korea, Republic of
Green Cross Corporation

Completed

A Study to Evaluate the Efficacy and Safety of GC3110A in Healthy Subjects Aged 65 Years and Older

Influenza, Human

Korea, Republic of
Green Cross Corporation

Completed

A Study to Evaluate the Efficacy and Safety of 'GC3110A(QIV)' in Healthy Children

Influenza

Korea, Republic of
Green Cross Corporation

Unknown

A Prospective Observational Study on Discontinuation of Medication of Shinbaro Capsule

Osteoarthritis

Korea, Republic of
Green Cross Corporation

Unknown

A Multicenter, Double-blind, Parallel, Non-inferiority, Phase III Study

Influenza

Korea, Republic of
Green Cross Corporation

Completed

To Evaluate the Effectiveness(Immunogeneicity) and Safety of 'GC1107' Administered Intramuscularly in Healthy Adults

Bacterial Infections

Korea, Republic of
Green Cross Corporation

Completed

Safety and Efficacy of Hunterase (GC1111)

Hunter Syndrome

Korea, Republic of
Green Cross Corporation

Completed

To Evaluate the Safety and Efficacy of GC1111 (Recombinant Human Iduronate-2-sulfatase) in Hunter Syndrome Patients

Mucopolysaccharidosis II

Korea, Republic of
Acerus Biopharma Inc.

Terminated

Evaluation of Testosterone Nasal Gel in Hypogonadal Boys

Hypogonadism

United Kingdom
Green Cross Corporation

Completed

A Study to Assess Safety, Efficacy, Immunogenicity, PK of GC1118 With Combination Chemotherapy

Metastatic Colorectal Cancer | Solid Tumor

Korea, Republic of
Green Cross Corporation

Withdrawn

Study of Immune Globulin Intravenous (Human) GC5101F in Subjects With Primary Humoral Immunodeficiency

Primary Immune Deficiency Disorder
Green Cross Corporation

Unknown

A Study to Evaluate the Safety and Efficacy(Immunogenicity) of GC3111 in Healthy Adults

Whooping Cough | Tetanus | Diphtheria

Korea, Republic of
Green Cross Corporation

Completed

A Study to Evaluate the Safety and Efficacy(Immunogenicity) of GC3114 in Healthy Adults

Influenza, Human

Korea, Republic of
Green Cross Corporation

Unknown

Safety Study of GC1118 (Recombinant Human Anti-EGFR Antibody) in Patients With Advanced Solid Cancer

Neoplasm Metastasis | Gastric Cancer | Colorectal Cancer

Korea, Republic of
Green Cross Corporation

Completed

A Phase 2 Study of GC1102 (Recombinant Hepatitis B Immunoglobulin) in HBV-related Liver Transplant Recipients

Hepatitis B Infection

Korea, Republic of
Green Cross Corporation

Completed

Evaluate the Safety and Exploratory Efficacy of GC1119

Fabry Disease

Korea, Republic of
Green Cross Corporation

Unknown

Study of Idursulfase-beta (GC1111) in Hunter Syndrome

Mucopolysaccharidosis II
Green Cross Corporation

Completed

A Multicenter, Double-blind, Parallel Phase III Study

Influenza

Korea, Republic of
Green Cross Corporation

Completed

Study to Evalutate Long-term Immunity of Hantavax in High Risk Population of HFRS

Infection
Green Cross Corporation

Completed

Study for Hyalobarrier to Evaluate Anti-adhesive Effect and Safety Compared to Guardix-SG After Thyroidectomy

Thyroid Disease

Korea, Republic of

Clinical Trials Sponsored by Arbutus Biopharma Corporation

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