Clinical Trials Sponsored by Ascent

Total 296 results

R-Pharm
Ascent

Completed

A Pharmacokinetic Study of Narlaprevir as a Single Dose or With Ritonavir Combination in Patients With Hepatic Impairment and Healthy Matched Volunteers

Hepatic Impairment

Georgia, Russian Federation
ASCEND Therapeutics

Completed

Study of Afimoxifene Gel to Treat Cyclic Mastalgia in Premenopausal Women

Cyclic Breast Pain, Cyclic Mastalgia
Ascenta Therapeutics

Completed

Phase II Safety and Efficacy Study of Single-agent AT-101 in Patients With Relapsed or Refractory B-cell Malignancies

Follicular Lymphoma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Diffuse Large Cell Lymphoma | Small Lymphocytic Lymphoma

United States
Ascenta Therapeutics

Completed

A Study Comparing AT-101 in Combination With Docetaxel and Prednisone Versus Docetaxel and Prednisone in Men With Chemotherapy-Naïve Metastatic Hormone Refractory Prostate Cancer (HRPC)

Hormone Refractory Prostate Cancer

United States, Russian Federation
Ascenta Therapeutics

Completed

Safety & Efficacy Study of AT-101 in Combination w/ Rituximab in Previously Untreated Grade I-II Follicular Non-Hodgkin's Lymphoma

Follicular Lymphoma

United States
Ascenta Therapeutics

Completed

A Randomized Phase 2 Study of AT-101 in Combination With Docetaxel in Relapsed/Refractory Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer

Russian Federation, United States, Ukraine
Ascenta Therapeutics

Completed

Phase 2 Safety and Efficacy Study of AT-101 in Combination With Rituximab in Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

United States
Ascenta Therapeutics

Terminated

An Open-label, Single-center, Phase 1/ 2 Study of Chemoradiotherapy and AT-101 in Patients With Locally Advanced Esophageal or Gastroesophageal Junction Cancer

Locally Advanced Esophageal or GE Junction Cancer

United States
Ascenta Therapeutics

Completed

Safety and Efficacy Study of AT-101 in Combination With Docetaxel and Prednisone in Men With HRPC

Prostate Cancer

United States
Ascenta Therapeutics

Completed

Study of AT-101 in Combination With Topotecan in Relapsed/Refractory Small Cell Lung Cancer

Small Cell Lung Cancer

United States, Russian Federation, Ukraine
ASCEND Therapeutics

Completed

Study of DHT-Gel to Treat the Symptoms of Low Testosterone in Men 55-80

Hypogonadism | Low Testosterone | Late Onset Hypogonadism

United States
Ascenta Therapeutics

Completed

A Study of Single-Agent AT-101 in Men With Hormone Refractory Prostate Cancer

Hormone Refractory Prostate Cancer

United States
Abbott
Ascent; Datamap; ClinIntel; Catalent

Completed

Study With Heptral in Subjects With Liver Disease Due to Alcohol Consumption

Intrahepatic Cholestasis Associated With Alcoholic Liver Disease

Russian Federation
Ascend Biopharmaceuticals Ltd

Completed

Safety and Efficacy of ASN-002 Combined With a Hedgehog Pathway Inhibitor

Basal Cell Nevus Syndrome | Basal Cell Carcinoma

Australia
AscentX Medical, Inc.

Recruiting

Bovine Atelocollagen Skin Sensitization Test

Healthy

United States
Ascend Biopharmaceuticals Ltd

Completed

A Study of the Efficacy and Safety of ASN-002 in Adult Patients With Low-risk Nodular Basal Cell Carcinoma (ASN-002-001)

Basal Cell Nevus Syndrome | Skin Neoplasm | Nodular Basal Cell Carcinoma of Skin

Australia
Ascend Biopharmaceuticals Ltd

Suspended

Study of ASN-002 to Treat Basal Cell Carcinomas (BCCs) in Individuals With Basal Cell Nevus Syndrome (BCNS)

Basal Cell Carcinoma in Basal Cell Nevus Syndrome

United States
Dascena

Withdrawn

Trial for the Early Identification of Acute Kidney Injury

Acute Kidney Injury
Dascena

Completed

Respiratory Decompensation and Model for the Triage of COVID-19 Patients (READY)

COVID-19 | Mortality | Coronavirus | Mechanical Ventilation

United States
Dascena

Completed

Effect of a Sepsis Prediction Algorithm on Clinical Outcomes

Severe Sepsis
Dascena

Not yet recruiting

Unsupervised Machine Learning for Clustering of Septic Patients to Determine Optimal Treatment

Sepsis | Septic Shock | Severe Sepsis
Dascena

Withdrawn

Gram Type Infection-Specific Sepsis Identification Using Machine Learning

Sepsis | Septic Shock | Severe Sepsis
Dascena

Completed

Identification of a Responsive Subpopulation to Hydroxychloroquine in COVID-19 Patients Using Machine Learning (IDENTIFY)

COVID-19 | Mortality | Coronavirus

United States
Dascena

Completed

COVID-19 Mortality Prediction Model

COVID-19 | Pneumonia | Mechanical Ventilation

United States
Dascena

Completed

Classification of COVID-19 Infection in Posteroanterior Chest X-rays

COVID-19

United States
ASCEND Therapeutics
Solvay Pharmaceuticals

Completed

Efficacy Study Comparing 0.9 g and 1.25 g Estrogel With Placebo for Vasomotor Symptoms and Vulvar and Vaginal Atrophy

Postmenopausal Symptoms

United States
Baskent University

Not yet recruiting

Comparison of Tramadol, Pethidine and Morphine in the Treatment of Pain After Thoracic Surgery

Analgesia | Thoracic Diseases

Turkey
Baskent University

Not yet recruiting

The Effect of Digital Technology-Supported Education on Patients Undergoing Breast Reconstruction After Mastectomy: A Randomized Controlled Study

Breast Cancer
Ascentys Ltd

Not yet recruiting

Feasibility Study of Game Technology in the Early Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease (G:DATA)

Dementia Alzheimers

United Kingdom
Baskent University

Not yet recruiting

Postoperative Nausea and Vomiting in Laparoscopic Abdominal Surgery (PONV)

Vomiting | Postoperative Nausea

Turkey
Baskent University

Recruiting

Restritive and Liberal Fluid Management and Colonoscopy

Colonoscopy | Intravenous Infusions | Sedoanalgesia

Turkey
Baskent University

Recruiting

Logotherapy Counseling Programme for Palliative Care Patients With Chronic Sorrow

Cancer | Palliative Care

Turkey
Baskent University

Recruiting

The Effect of Diabetes Mellitus in Colonoscopy Under Sedoanalgesia

Diabetes Mellitus, Type 2 | Sedoanalgesia

Turkey
Baskent University

Recruiting

Taping for Saliva Control in Cerebral Palsy

Cerebral Palsy

Turkey
Baskent University

Recruiting

Validity and Reliability of the Expectation Scale in the Treatment of Chronic Pain

Chronic Pain | Musculoskeletal Disorder

Turkey
Baskent University

Completed

Acupressure and Fistula Needle Insert Pain Management

Chronic Kidney Disease Stage 5 (Disorder)

Turkey
Baskent University

Completed

Blood Transfusion Applications in Hip Replacements

Blood Transfusion | Hip Replacement | Anesthesia Management

Turkey
Baskent University

Completed

Evaluation of the Effectiveness of Calcium Phosphate Containing Desensitizer on Postoperative Sensitivity

Postoperative Pain

Turkey
Alucent Biomedical

Completed

Natural Vascular Scaffold (NVS) Therapy for Treatment of Atherosclerotic Lesions (Activate I)

Peripheral Arterial Disease | Peripheral Vascular Diseases | Catheterization, Peripheral

United States
Baskent University

Completed

Physical Fitness in Young Healthy Adults After COVID-19 Infection

COVID-19

Turkey
Baskent University

Completed

Home-Based Exercise Training in Older Adults During the COVID-19 Pandemic

Aging | COVID-19 Pandemic | Physical Inactivity

Turkey
Baskent University

Completed

Effects of Sterile Kinesio Tape on Anterior Cruciate Ligament Reconstruction

Edema | Postoperative Pain

Turkey
Baskent University

Completed

Effects of a Computerised Exercise System on Functionality of the Arm,Cognition and Quality of Life in Stroke Patients

Stroke | Hemiplegia | Neuronal Plasticity

Turkey
Baskent University

Completed

Comparison of the Effects of Oil Pulling Therapy With Different Oils

Gingivitis

Turkey
Baskent University

Completed

Does the Length of Hospital Stay for Rehabilitation Affect Functional Outcomes in Stroke Patients

Stroke

Turkey
Baskent University

Completed

Effect of Dental Pulp Stem Cells and L-PRF After Impacted Third Molar Extraction

Periodontal Pocket | Third Molar | Stem Cell

Turkey
Baskent University

Completed

The Distribution of Gingival Display and Possible Related Factors Resulting in Gummy Smile

Gummy Smile

Turkey
Baskent University

Completed

Aquatic and Land Exercises in Chronic Low Back Pain

Chronic Low-back Pain

Turkey
Baskent University

Completed

Lacrimal Dilator-Facilitated vs Standard Sub-Tenon's Block

to Compare Lacrimal Dilator-facilitated Incisionless and Standard STB With Wescott Scissors

Turkey
Baskent University

Completed

Evaluating the Well-being Among Dental Students With Warwick-Edinburg Mental Well-Being Scale

Well Being

Turkey

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