Clinical Trials Sponsored by Astellas Institute for Regenerative Medicine

Total 940 results

Astellas Institute for Regenerative Medicine

Completed

Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)

Stargardt's Macular Dystrophy

United Kingdom
Astellas Institute for Regenerative Medicine

Completed

A Follow up Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)

Stargardt's Macular Dystrophy

United Kingdom
Astellas Institute for Regenerative Medicine

Completed

Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Patients With AMD

Age-Related Macular Degeneration

United States
Astellas Institute for Regenerative Medicine

Recruiting

A Study of the Safety and Tolerability of ASP7317 in Senior Adults Who Are Losing Their Clear, Sharp Central Vision Due to Geographic Atrophy Secondary to Dry Age-related Macular Degeneration

Age-Related Macular Degeneration

United States
Astellas Institute for Regenerative Medicine

Enrolling by invitation

A Safety Surveillance Study in Subjects With Macular Degenerative Disease Treated With Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cell Therapy

Macular Degenerative Disease

United Kingdom, United States
Astellas Institute for Regenerative Medicine

Completed

Safety and Tolerability of Sub-retinal Transplantation of hESC Derived RPE (MA09-hRPE) Cells in Patients With Advanced Dry Age Related Macular Degeneration (Dry AMD)

Dry Age Related Macular Degeneration

United States
Astellas Institute for Regenerative Medicine

Completed

Sub-retinal Transplantation of hESC Derived RPE(MA09-hRPE)Cells in Patients With Stargardt's Macular Dystrophy

Stargardt's Macular Dystrophy

United States
Astellas Institute for Regenerative Medicine

Completed

Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Stargardt Macular Dystrophy Patients

Stargardt's Macular Dystrophy

United States
Astellas Institute for Regenerative Medicine

Withdrawn

Study to Evaluate Sub-retinal Transplantation of Retinal Pigmented Epithelial Cells in Patients With Dry AMD (PORTRAY)

Age-Related Macular Degeneration

United States
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Adipose Derived Stem Cell Therapy for Autism

Autism

United States
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Safety and Efficacy of Adipose Derived Stem Cells for Non-Ischemic Congestive Heart Failure

Non-Ischemic Congestive Heart Failure

Mexico
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Safety and Efficacy of Adipose Derived Stem Cells for Congestive Heart Failure

Ischemic Congestive Heart Failure

Mexico
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Study to Assess the Safety and Cardiovascular Effects of Autologous Adipose-Derived Stromal Cells Implantation In Patients During the Acute Recovery Phase of ST-Elevation Myocardial Infarction (Acute MI)

Acute Myocardial Infarction

United States
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Study to Assess the Safety and Effects of Autologous Adipose-Derived Stromal Cells in Patients After Stroke

Stroke

Mexico
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Study to Assess the Safety and Effects of Autologous Adipose-Derived Stem Cells in Patients With Frailty Syndrome

Frailty Syndrome

Mexico
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Safety and Effects of Autologous Adipose-Derived Stromal Cells in Patients With Diffuse Lesions in the Brain

Brain Lesion (General)

Mexico
Ageless Regenerative Institute
Instituto de Medicina Regenerativa

Withdrawn

Study to Assess the Safety and Effects of Autologous Adipose-Derived Stromal Cells Delivered in Patients With Renal Failure

Renal Failure

Mexico
ViaCyte
California Institute for Regenerative Medicine (CIRM)

Terminated

A Safety, Tolerability, and Efficacy Study of VC-01™ Combination Product in Subjects With Type I Diabetes Mellitus

Type 1 Diabetes Mellitus

Canada, United States
jCyte, Inc
California Institute for Regenerative Medicine (CIRM)

Completed

Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa

Retinitis Pigmentosa

United States
Gilead Sciences
California Institute for Regenerative Medicine (CIRM)

Completed

CAMELLIA: Anti-CD47 Antibody Therapy in Haematological Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United Kingdom
Neurona Therapeutics
California Institute for Regenerative Medicine (CIRM)

Recruiting

FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy

Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis

United States
ExCellThera inc.
California Institute for Regenerative Medicine (CIRM)

Withdrawn

US Phase I Study of ECT-001-CB in Patients With Sickle-Cell Disease

Sickle Cell Disease | Umbilical Cord Blood | Hematopoietic Cell Proliferation

United States
Angiocrine Bioscience
California Institute for Regenerative Medicine (CIRM)

Completed

Trial of AB-110 in Adults With Hematologic Malignancies Undergoing Cord Blood Transplantation

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia in Remission | Other Acute Leukemias

United States
jCyte, Inc
California Institute for Regenerative Medicine (CIRM)

Completed

Safety of a Single, Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Retinitis Pigmentosa

Retinitis Pigmentosa (RP)

United States
Genascence Corporation
California Institute for Regenerative Medicine (CIRM)

Recruiting

Safety and Pharmacodynamics of GNSC-001 Intra-articular Injection for Knee Osteoarthritis (DONATELLO)

Knee Osteoarthritis | Osteoarthritis, Knee | Osteo Arthritis Knee

United States
Aspen Neuroscience
California Institute for Regenerative Medicine (CIRM)

Enrolling by invitation

Phase 1/2a Study of ANPD001 in Parkinson Disease (ASPIRO)

Parkinson Disease

United States
Angiocrine Bioscience
California Institute for Regenerative Medicine (CIRM)

Terminated

A Study of the Effects of AB-205 in Patients With Lymphoma Undergoing Autologous Hematopoietic Cell Transplantation (E-CELERATE)

Hodgkin Lymphoma | Non Hodgkin Lymphoma

United States
jCyte, Inc
California Institute for Regenerative Medicine (CIRM)

Completed

Safety and Efficacy of Intravitreal Injection of Human Retinal Progenitor Cells in Adults With Retinitis Pigmentosa

Retinitis Pigmentosa

United States
Angiocrine Bioscience
California Institute for Regenerative Medicine (CIRM)

Completed

Trial of AB-205 in Adults With Lymphoma Undergoing High-Dose Therapy and Autologous Stem Cell Transplantation

Hodgkin Lymphoma | Non-hodgkin Lymphoma

United States
Gilead Sciences
California Institute for Regenerative Medicine (CIRM)

Completed

Study of Magrolimab (Hu5F9-G4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer

Colorectal Cancer | Solid Tumor

United States
COR clinic of Regenerative Medicine

Completed

Skin Rejuvenation Using Stem Cell Secretome

Skin Rejuvenation

Lebanon
Immune-Onc Therapeutics
California Institute for Regenerative Medicine (CIRM)

Recruiting

IO-202 as Monotherapy and IO-202 Plus Azacitidine ± Venetoclax in Patients in AML and CMML

CMML | AML With Monocytic Differentiation

United States
Poseida Therapeutics, Inc.
California Institute for Regenerative Medicine (CIRM)

Terminated

P-BCMA-101 Tscm CAR-T Cells in the Treatment of Patients With Multiple Myeloma (MM)

Multiple Myeloma

United States
Rocket Pharmaceuticals Inc.
California Institute for Regenerative Medicine (CIRM)

Completed

A Clinical Trial to Evaluate the Safety and Efficacy of RP-L201 in Subjects With Leukocyte Adhesion Deficiency-I

Leukocyte Adhesion Defect - Type I

Spain, United States, United Kingdom
Rocket Pharmaceuticals Inc.
California Institute for Regenerative Medicine (CIRM)

Terminated

A Trial to Evaluate Safety and Efficacy of RP-L401-0120 in Subjects With Infantile Malignant Osteopetrosis

Infantile Malignant Osteopetrosis

United States
Poseida Therapeutics, Inc.
California Institute for Regenerative Medicine (CIRM)

Active, not recruiting

Long-Term Follow-Up Study for Subjects Treated With P-BCMA-101

Multiple Myeloma

United States
Instituto de Medicina Regenerativa

Recruiting

Pilot Study of Neoantigen Peptides and Leukine for the Treatment of Neoplasms

Neoplasms

Mexico
Brainstorm-Cell Therapeutics
California Institute for Regenerative Medicine (CIRM)

Completed

Safety and Efficacy of Repeated Administrations of NurOwn® in ALS Patients

Amyotrophic Lateral Sclerosis (ALS)

United States
Medeor Therapeutics, Inc.
California Institute for Regenerative Medicine (CIRM)

Active, not recruiting

Cellular Immunotherapy in Recipients of HLA-matched, Living Donor Kidney Transplants

Kidney Transplant Rejection

United States, Canada
The Foundation for Orthopaedics and Regenerative...

Recruiting

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for PCOS

Polycystic Ovary Syndrome | PCOS | Polycystic Ovary Syndrome (PCOS)

Antigua and Barbuda, Greece
The Foundation for Orthopaedics and Regenerative...

Recruiting

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Stroke

Stroke

Antigua and Barbuda, Argentina, Mexico
The Foundation for Orthopaedics and Regenerative...

Not yet recruiting

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Parkinson's Disease

Parkinson Disease

Antigua and Barbuda
The Foundation for Orthopaedics and Regenerative...

Recruiting

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Pulmonary Diseases

Chronic Obstructive Pulmonary Disease | Asthma | Pulmonary Disease

Antigua and Barbuda
The Foundation for Orthopaedics and Regenerative...

Recruiting

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Diabetes

Diabetes

Antigua and Barbuda, Argentina, Mexico
The Foundation for Orthopaedics and Regenerative...

Recruiting

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for MS

Multiple Sclerosis

Antigua and Barbuda, Argentina
Regeneris Medical
Global Alliance for Regenerative Medicine

Recruiting

Biocellular-Cellular Regenerative Treatment Scaring Alopecia and Alopecia Areata (SAAA)

Alopecia Areata | Scarring Alopecia

United States
The Foundation for Orthopaedics and Regenerative...

Withdrawn

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Tourette Syndrome

Tourette Syndrome

Antigua and Barbuda
Instituto de Medicina Regenerativa

Completed

Pilot Study of Neoantigen Peptides for the Treatment of Neoplasms

Neoplasms

Mexico
The Foundation for Orthopaedics and Regenerative...

Recruiting

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Ovarian Failure

Ovarian Failure

Antigua and Barbuda
The Foundation for Orthopaedics and Regenerative...

Recruiting

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Testicular Injury and Oligospermia

Oligospermia | Testicular Injury

Antigua and Barbuda

Clinical Trials Sponsored by Astellas Institute for Regenerative Medicine

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