Clinical Trials Sponsored by Astes

Total 140 results

Astes

Completed

Derivation and Validation of a Combination of BOSTON Score and DES-OSA Score for Selection of OSA Patients.

Obstructive Sleep Apnea

Belgium
Astes

Completed

Influence of Different Parameters on Extubation Time After Cardiac Surgery.

Thoracic Surgery

Belgium
Astes

Completed

Inter Scorers Agreement for OSA Screening Scores.

Sleep Apnea, Obstructive

Belgium
Astes

Completed

Influence of Resident's Degree of Formation on the Quality of Care Delivered to the Patients.

Anesthesia Complication

Belgium
Astes

Completed

Comparison of Oral Zaldiar With Intravenous Paracetamol and Tramadol

Pain
Astes

Completed

Comparison of Delta Pulse Pressure and Delta Down Before and After Sternotomy

Hemodynamics

Belgium
Astes

Withdrawn

Interest of the OSA (Obstructive Sleep Apnea) Predictive Scores in the Prognosis of Postoperative Mortality of Femoral Neck Fractures

Femoral Neck Fracture

Belgium
Astes

Not yet recruiting

Comparison of Methodology Proposed by the SFAR for the Detection by Videoconference of Obstructive Sleep Apnea.

Obstructive Sleep Apnea
Astes

Completed

Comparison of Demographic Data Mentioned by the Patients or Measured by a Physician

Obstructive Sleep Apnea

Belgium
Astes

Completed

Comparison of Two Dosages of Heparin Before Extracorporeal Circulation

Extracorporeal Circulation; Complications

Belgium
Astes

Withdrawn

Determination of Optimal Cutoff Value for Screening Severe Hypoxemic OSA (Obstructive Sleep Apnea) Patients

Sleep Apnea, Obstructive

Belgium
Astes

Completed

Influence of Different Methods of Measurement in the Accuracy of DES-OSA and P-SAP Scores

Sleep Apnea, Obstructive

Belgium
Astes

Completed

Comparison of Preoperative Screening Score for Obstructive Sleep Apnea (OSA)

Sleep Apnea, Obstructive

Belgium
Astes

Withdrawn

Practice Survey on Femoral Neck Fractures and the Incidence of Type of Anesthesia on Patient Outcome

Femoral Neck Fractures

Belgium
Astes

Completed

Comparision of the Use in Marcaine and Chloroprocaine in Rachianesthesia for the Surgical Correction of Inguinal Hernia.

Pain

Belgium
Astes

Completed

Comparison of Three Methods of Anesthesia to Achieve a Nerve Block Anesthesia.

Anesthesia

Belgium
Astes

Withdrawn

Influence of Extracorporeal Circulation on the Development of OSA (Obstructive Sleep Apnea)

Coronary Artery Disease
Astes

Completed

Influence of Tobacco Smoking on the Development of Obstructive Sleep Apnea (OSA)

Obstructive Sleep Apnea | Tobacco Use
Astes

Completed

Comparison of the New Algorithm of STOP-Bang in the Detection of Severe OSA Patients

Apnea, Sleep

Belgium
Astes

Completed

Comparison of STOP-BANG and DES-OSA as Predictive Score for Difficult Intubation.

Bariatric Surgery Candidate

Belgium
Astes

Completed

Impact of Smoking, Benzodiazepine (BZD) Use and Obesity on Severe Obstructive Sleep Apnea (sOSA)

Smoking | Obesity | Obstructive Sleep Apnea
Astes

Completed

Clinical Use of Prilocaine Chlorhydrate Among a General Surgical Population

Anesthesia

Belgium
Astes

Completed

Adherence to Continuous Positive Airway Pressure Among Obstructive Sleep Apnoea Patients.

Sleep Apnea, Obstructive

Belgium
Asten Sante

Recruiting

Consequences of Respiratory Devices on Caregivers (CAP2) (CAP2)

Quality of Life

France
Astel Medica

Completed

First Line Dose-efficacy Study of Bactecal® D Liquid for Infant Colic (BACTECOLIC)

Colic

Belgium
Eric DEFLANDRE, MD, FCCP

Completed

Comparison of Different Screening Score for Hypoxemic OSA (Obstructive Sleep Apnea) With the Results of a Polysomnography (PSG)

Sleep Apnea, Obstructive

Belgium
Astex Pharmaceuticals, Inc.

Recruiting

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment

Acute Myeloid Leukemia | Myelodysplastic Syndromes

Spain, Poland, Bulgaria, Lithuania, Slovakia, Romania
Astex Pharmaceuticals, Inc.

Recruiting

Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Renal Impairment

Acute Myeloid Leukemia | Myelodysplastic Syndromes

Spain, Poland, Bulgaria, Lithuania, Slovakia, Romania
Astex Pharmaceuticals, Inc.

Active, not recruiting

A Study of TAS1440 With ATRA in Subjects With r/r AML

Acute Myeloid Leukemia

United States
Astex Pharmaceuticals, Inc.

Active, not recruiting

Study of ASTX295 in Patients With Solid Tumors With Wild-Type p53

Solid Tumor

United States
Astex Pharmaceuticals, Inc.

Completed

Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs

Myelodysplastic Syndromes | Leukemia, Myelomonocytic, Chronic

United States, Spain, Korea, Republic of, France, Denmark, Canada, Germany, Italy, Czechia, United Kingdom, Poland, Japan, Sweden, Belgium
Astex Pharmaceuticals, Inc.

Terminated

Guadecitabine Extension Study

Acute Myeloid Leukemia | Myeloid Dysplastic Syndrome

United States, Taiwan, Korea, Republic of, Canada, Spain, Japan, Italy, Austria, Denmark
Astex Pharmaceuticals, Inc.

Terminated

A Study of ASTX660 as a Single Agent and in Combination With ASTX727 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
Astex Pharmaceuticals, Inc.

Completed

Safety Study to Determine the Maximum Tolerated Dose, Pharmacokinetics and Pharmacodynamics of Oral MP470, a Multitargeted Tyrosine Kinase Inhibitor, in Patients With Solid Malignancies

Solid Tumors

United States
Astex Pharmaceuticals, Inc.

Completed

A Study of HSP90 Inhibitor AT13387 Alone or in Combination With Abiraterone Acetate

Prostate Cancer

United States, United Kingdom, Spain, Canada
Astex Pharmaceuticals, Inc.

Terminated

Orathecin + Gemcitabine Versus Placebo + Gemcitabine in Chemonaive Non-Resectable Pancreatic Cancer

Pancreatic Cancer

United States
Astex Pharmaceuticals, Inc.

Completed

Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Chronic Phase Who Are Refractory to Imatinib Mesylate (Gleevec)

Chronic Myelogenous Leukemia

United States, Canada
Astex Pharmaceuticals, Inc.

Recruiting

A Study of ASTX030 (Cedazuridine in Combination With Azacitidine) in MDS, CMML, or AML

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Chronic Myelocytic Leukemia | Myelodysplastic Syndrome/Neoplasm

United States
Astex Pharmaceuticals, Inc.

Active, not recruiting

A Study of Tolinapant in Combination With Oral Decitabine/Cedazuridine and Oral Decitabine/Cedazuridine Alone in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma (R/R PTCL)

Relapsed/Refractory Peripheral T-cell Lymphoma

Spain, United States, Australia, France, United Kingdom, Italy, Poland
Astex Pharmaceuticals, Inc.

Active, not recruiting

Phase 1-2 Study of Low Dose ASTX727 (ASTX727 LD) in Lower Risk MDS

Myelodysplastic Syndromes

Spain, United States, Belgium, Canada, Germany, Italy
Astex Pharmaceuticals, Inc.

Terminated

A Study of Oral Decitabine/Cedazuridine in Combination With Magrolimab in Participants With Intermediate- to Very High-Risk Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes

United States
Astex Pharmaceuticals, Inc.

Terminated

A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms

Acute Myeloid Leukemia | Myeloproliferative Neoplasm | Myelodysplastic/Myeloproliferative Neoplasm

United States, Canada
Astex Pharmaceuticals, Inc.

Completed

SGI-110 in Combination With Carboplatin in Ovarian Cancer (SGI-110)

Ovarian Cancer

Canada, United States, United Kingdom
Astex Pharmaceuticals, Inc.

Completed

SGI-110 in Patients With Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML)

AML | MDS | CMML

United States, Canada
Astex Pharmaceuticals, Inc.

Completed

Pharmacokinetic Guided Dose Escalation and Dose Confirmation With Oral Decitabine and Oral Cytidine Deaminase Inhibitor (CDAi) in Patients With Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndrome | MDS

United States, Canada
Astex Pharmaceuticals, Inc.

Completed

A Phase 1 Study to Evaluate the Effect of Food on Pharmacokinetics of ASTX029

Healthy Volunteers

United States
Astex Pharmaceuticals, Inc.

Completed

Safety of MP470 in Combination With Standard-of-Care Chemotherapy Regimens to Treat Solid Tumors (SGI-0470-02)

Malignant Disease

United States
Astex Pharmaceuticals, Inc.

Terminated

Safety of SGI-1776, A PIM Kinase Inhibitor in Refractory Prostate Cancer and Relapsed/Refractory Non Hodgkin's Lymphoma

Prostate Cancer | Non-Hodgkins Lymphoma

United Kingdom, United States
Astex Pharmaceuticals, Inc.

Completed

SGI-110 in the Treatment of Advanced Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma

United States, United Kingdom, Canada
Astex Pharmaceuticals, Inc.

Terminated

Study to Assess the Safety of Escalating Doses of AT9283, in Patients With Leukemias

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia

United States

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