Clinical Trials Sponsored by AstraZeneca UK Ltd

Total 286 results

Cancer Research UK
AstraZeneca

Completed

A Phase I Trial of Vandetanib (AZD6474) and Selumetinib (AZD6244) for Solid Tumours Including Non Small Cell Lung Cancer (VanSel-1)

Cancer | Non Small Cell Lung Cancer

United Kingdom
Cancer Research UK
AstraZeneca

Completed

A Phase I Trial of AZD3965 in Patients With Advanced Cancer

Adult Solid Tumor | Burkitt Lymphoma | Diffuse Large B Cell Lymphoma

United Kingdom
Chandrikha Chandrasekharan
AstraZeneca; Biocompatibles UK Ltd

Suspended

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer (iRE-C)

Metastatic Colorectal Cancer | Colorectal Neoplasms | Rectal Cancer | Colon Cancer | Colorectal Cancer Metastatic | Liver Metastases | Colo-rectal Cancer | Colorectal Carcinoma | Colorectal Adenocarcinoma | Liver Metastasis Colon Cancer

United States
Nutricia UK Ltd

Recruiting

Evaluation of Four New Ready to Drink Oral Nutritional Supplements: Adult ONS Trial

Malnutrition

United Kingdom
Nutricia UK Ltd

Completed

Bolus Pouch Feed Study

Stroke | Cancer | Gastrointestinal Dysfunction | Neurological Disorder | Oral Complication

United Kingdom
Nutricia UK Ltd

Completed

2kcal Tube Feed Study

Cancer | Enteral Nutrition

United Kingdom
Nutricia UK Ltd

Completed

GMP Case Studies of Tolerance, Safety and Acceptability in PKU and TYR

PKU | Tyrosinemias

United Kingdom
Inflazome UK Ltd

Completed

Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With Inzomelid

Healthy

Australia
Nutricia UK Ltd

Completed

Evaluating the Efficacy of PKU Synergy in Patients Expressing Phenylketonuria or Hyperphenylalaninemia

Phenylketonurias | Hyperphenylalaninaemia, Type I

United Kingdom
Nutricia UK Ltd

Completed

High vs Standard Energy Children's Drink Study

Growth Failure
Nutricia UK Ltd

Completed

Amino Acid Feed Children's Study

Milk Hypersensitivity
Nutricia UK Ltd

Completed

An Investigation of the Efficacy of Oral Nutritional Supplements in Participants at Risk of Malnutrition

Malnutrition

United Kingdom
Nutricia UK Ltd

Completed

Nutritional Supplement Compliance Study (NSCS)

Undernutrition

United Kingdom
Nutricia UK Ltd

Recruiting

Childrens Real Food Tolerance Study

Malnutrition, Child

United Kingdom
Nutricia UK Ltd

Suspended

IDDSI Nutritional Drink for Dysphagia Study

Malnutrition | Dysphagia

United Kingdom
Nutricia UK Ltd

Completed

Protein Top-up Acceptability Study for Patients With Increased Protein Needs

Stroke | Cancer | Respiratory Disease | Neurological Injury

United Kingdom
Nutricia UK Ltd

Completed

HMF Preterm Case Studies

Preterm Infants

United Kingdom
Inflazome UK Ltd

Completed

Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With IZD334

Healthy Volunteers | Cryopyrin Associated Periodic Syndrome

Australia
Nutricia UK Ltd

Completed

GMP Drink for PKU Study

Phenylketonuria

United Kingdom
Nutricia UK Ltd

Withdrawn

Compliance, Tolerance and Acceptability of a Tablet Protein Substitute for the Dietary Management of Phenylketonuria

Phenylketonurias
Nutricia UK Ltd

Completed

Hospital Discharge Oral Nutrition Support Trial

Malnutrition

United Kingdom
Nutricia UK Ltd

Recruiting

Hydrolysed Rice Formula Study

Cow's Milk Protein Allergy

United Kingdom
Nutricia UK Ltd

Not yet recruiting

PKU Low Calorie Drink Study

Phenylketonurias | Hyperphenylalaninaemia
Nutricia UK Ltd

Active, not recruiting

Synbiotics Cohort Study

Cows Milk Allergy

United Kingdom
Nutricia UK Ltd

Completed

Synbiotic Extensively Hydrolysed Feed Study

Cow Milk Allergy

United Kingdom
Inflazome UK Ltd

Withdrawn

PK Study in Patients With Parkinson's Disease With IZD174

Parkinson Disease
Nutricia UK Ltd

Completed

High Energy High Protein Tube Feed Study

Nutrition

United Kingdom
Nutricia UK Ltd

Completed

Ketogenic Diet Drink Study

Intractable Epilepsy

United Kingdom
Biotronik UK Ltd.

Unknown

BIOFLOW-III UK Satellite Registry Orsiro Stent System

Coronary Artery Diseases

United Kingdom
Calcivis Ltd
Medsource UK Ltd.

Completed

Safety and Performance Evaluation of the Calcivis System

Dental Caries

United Kingdom
Calcivis Ltd
Medsource UK Ltd.

Completed

Caries Lesion Activity in Orthodontic Patients - Calcivis System

Dental Caries

United Kingdom
Oxford Vacmedix UK Ltd.

Recruiting

First-in-human Study of OVM-200 as a Therapeutic Cancer Vaccine

Ovarian Cancer | Prostate Cancer | Non Small Cell Lung Cancer

United Kingdom
MeiraGTx UK II Ltd

Completed

A Phase 1 Open-Label, Dose Escalation Study to Determine the Optimal Dose, Safety, and Activity of AAV2hAQP1 in Subjects With Radiation-Induced Parotid Gland Hypofunction and Xerostomia

Head and Neck Cancer | Radiation-Induced Parotid Gland Hypofunction | Xerostomia Due to Radiotherapy

United States, Canada
MeiraGTx UK II Ltd

Completed

Natural History Study of Patients With Leber Congenital Amaurosis Associated With Mutations in RPE65

Leber Congenital Amaurosis

United Kingdom, United States
MeiraGTx UK II Ltd

Completed

Natural History Study for Achromatopsia

Achromatopsia

United Kingdom
BSN Medical Ltd. UK

Terminated

A Study to Evaluate the Benefits of Using a Range of Wound Care Products From a Single Manufacturer

Wound - in Medical Care

United Kingdom
Eliem Therapeutics (UK) Ltd.

Completed

Efficacy and Safety of ETX-018810 in Subjects With Lumbosacral Radicular Pain

Lumbosacral Radiculopathy

United States
Eliem Therapeutics (UK) Ltd.

Completed

Efficacy and Safety of ETX-018810 for the Treatment of Diabetic Peripheral Neuropathic Pain

Diabetic Peripheral Neuropathic Pain | Diabetic Peripheral Neuropathy

United States
MeiraGTx UK II Ltd

Completed

Clinical Trial of Gene Therapy for the Treatment of Leber Congenital Amaurosis (LCA) (OPTIRPE65)

Leber Congenital Amaurosis

United Kingdom, United States
University College, London
AstraZeneca; Cancer Research UK; Kidney Cancer UK

Recruiting

Renal Adjuvant MultiPle Arm Randomised Trial (RAMPART)

Renal Cell Carcinoma

United Kingdom
Acacia Pharma Ltd
Paion UK Ltd.

Active, not recruiting

Investigation of Remimazolam in Children Undergoing Sedation for Medical Procedures

Pediatric ALL

United States, Denmark
Paion UK Ltd.
Chiltern International Ltd.; HFL Ltd.

Completed

An Efficacy and Safety Study to Compare Morphine 6-glucuronide (M6G) and Morphine in Patients Suffering With Post-Operative Pain for at Least 24 Hours

Postoperative Pain

France, Germany, Netherlands, Poland, United Kingdom, Czechia
Medialis Ltd.
Metabolic Support UK

Completed

Retrospective and Prospective Disease Progression and Quality of Life in XLH

X-linked Hypophosphatemia (XLH)

United Kingdom
Kiniksa Pharmaceuticals (UK), Ltd.

Completed

Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis (RHAPSODY)

Recurrent Pericarditis

United States, Israel, Australia, Italy
University of Birmingham
AstraZeneca; Cancer Research UK

Terminated

International Trial of Selumetinib in Combination With Dexamethasone for the Treatment of Acute Lymphoblastic Leukaemia (SeluDex)

Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia, Pediatric | Acute Lymphoblastic Leukemia, in Relapse | Acute Lymphoblastic Leukemia, Adult | Acute Lymphoblastic Leukemia Recurrent

United Kingdom, Denmark, Netherlands
University of Birmingham
AstraZeneca; Cancer Research UK

Completed

WEE1 Inhibitor With Cisplatin and Radiotherapy: A Trial in Head and Neck Cancer (WISTERIA)

Larynx Cancer | Oral Cavity Squamous Cell Carcinoma | Hypopharynx Squamous Cell Carcinoma

United Kingdom
Imperial College London
AstraZeneca; Cancer Research UK

Completed

AZD4547 & Anastrozole or Letrozole (NSAIs) in ER+ Breast Cancer Patients Who Have Progressed on NSAIs (RADICAL) (RADICAL)

Breast Cancer

United Kingdom
Paion UK Ltd.
Aptiv Solutions

Completed

Remimazolam Phase II Cardiac Anesthesia Study

General Anesthesia

Germany
Verisfield UK Ltd. Greek Branch

Completed

Study to Determine the Bioequivalence of Two Products Containing Rosuvastatin (20 mg/Tablet)

Healthy

India
Verisfield UK Ltd. Greek Branch

Completed

Study to Determine the Equivalence of Two Products Containing Metronidazole Benzoate

Healthy

Jordan

Clinical Trials Sponsored by AstraZeneca UK Ltd

Sponsors and Collaborators

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