Clinical Trials Sponsored by Baylor International Pediatric AIDS Initiative

Total 112 results

International AIDS Vaccine Initiative

Completed

Safety and Immunogenicity of TBC-M4, a MVA HIV Vaccine Alone or in a Prime-Boost Regimen With ADVAX DNA HIV Vaccine

HIV Infections

United Kingdom
International AIDS Vaccine Initiative

Completed

A Pilot Study of Pre-Exposure Prophylaxis (PrEP) to Evaluate Safety, Acceptability, and Adherence in At-risk Populations in Uganda, Africa

HIV Infection

Uganda
International AIDS Vaccine Initiative

Completed

A Pilot Study of Pre-Exposure Prophylaxis (PrEP) to Evaluate Safety, Acceptability, and Adherence in At-Risk Populations in Kenya, Africa

HIV Infections

Kenya
International AIDS Vaccine Initiative

Completed

A Phase I Trial to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer Vaccine, Adjuvanted

HIV/AIDS

United States
International AIDS Vaccine Initiative

Completed

Safety and Immunogenicity Study of SeV-G(NP) HIV Vaccine Administered Intranasally and Ad35-GRIN HIV Vaccine Given Intramuscularly in Prime-Boost Regimens in HIV-Uninfected Volunteers

HIV Infections

United Kingdom, Kenya, Rwanda
International AIDS Vaccine Initiative
GlaxoSmithKline

Completed

Safety and Immunogenicity Study of 2 Investigational Preventive HIV Vaccines

HIV Infections

Kenya, Zambia, Uganda
International AIDS Vaccine Initiative
Targeted Genetics Corporation

Completed

Safety and Immunogenicity Study of tgAAC09, an HIV Vaccine in an Adeno-associated Virus (AAV) Capsid (TGC14F)

HIV Infections | Human Immunodeficiency Virus Infections

Uganda, South Africa, Zambia
CMV Research Foundation
International AIDS Vaccine Initiative

Completed

Safety Study of Four Chimera Cytomegalovirus (CMV) Vaccines in Healthy Adult Males 30-50 Years of Age

Cytomegalovirus

United States
International AIDS Vaccine Initiative
University of Rochester

Completed

A Trial to Evaluate Ad35-GRIN/ENV HIV Vaccine in Healthy Adult Volunteers

HIV Infections | HIV

United States
International Maternal Pediatric Adolescent AIDS...

Completed

IMPAACT P1080: Psychiatric and Antiretroviral Medication Concentrations in HIV-infected and Uninfected Children and Adolescents (IMPAACT P1080)

HIV | ADHD

United States, Puerto Rico
International AIDS Vaccine Initiative
Universidad de Zaragoza; Biofabri, SLU

Not yet recruiting

A Study to Evaluate the Efficacy, Safety and Immunogenicity of MTBVAC in IGRA Positive Adolescents and Adults Living in a TB Endemic Region.

Tuberculosis (TB)
International AIDS Vaccine Initiative
Coalition for Epidemic Preparedness Innovations

Recruiting

A Lassa Fever Vaccine Trial in Adults and Children Residing in West Africa

Lassa Fever

Ghana, Liberia, Nigeria
International AIDS Vaccine Initiative
University of Rochester; Aaron Diamond AIDS Research Center

Completed

Safety and Immunogenicity of a Modified Vaccinia Ankara (MVA) HIV Vaccine in HIV Uninfected Adults

HIV Infection

United States
International AIDS Vaccine Initiative
University of Rochester; Aaron Diamond AIDS Research Center

Completed

Safety and Immunogenicity of a Plasmid HIV Vaccine in HIV Uninfected Adults (C001)

HIV Infection

United States
Elizabeth Glaser Pediatric AIDS Foundation
Canadian International Development Agency

Completed

Advancing Community Level Action for Improving MCH/PMTCT (ACCLAIM)

HIV

Zimbabwe, Swaziland, Uganda
International AIDS Vaccine Initiative
Biofabri, S.L; South African Tuberculosis Vaccine Initiative; Universidad de...

Completed

MTBVAC Study in Adults With and Without Latent Tuberculosis Infection in South Africa (A-050)

Tuberculosis

South Africa
International AIDS Vaccine Initiative
Biomedical Advanced Research and Development Authority

Active, not recruiting

Evaluation of Safety and Immunogenicity of rVSVΔG-SEBOV-GP Vaccine in Adults With Good General Health

Ebola Sudan Virus Disease

United States
MRC/UVRI and LSHTM Uganda Research Unit
International AIDS Vaccine Initiative

Recruiting

Feasibility of Identifying, Enrolling and Following Acute and Early HIV-1 Infected Individuals. (KILGORIS)

Acute Human Immunodeficiency Virus Type I Infection

Uganda
International AIDS Vaccine Initiative
Auro Vaccines LLC; Ichor Medical Systems Incorporated

Completed

Safety and Immunogenicity Study of HIV-MAG Vaccine +/- IL-12 and Ad35-GRIN/ENV in HIV-uninfected Volunteers

HIV Infections

Rwanda, Uganda, Kenya
International AIDS Vaccine Initiative
University of Nairobi; Medical Research Council-Oxford

Completed

A Phase IIA Trial to Evaluate the Safety and Immunogenicity of a DNA HIV-1 Vaccine Followed by an MVA HIV-1 Vaccine in HIV-uninfected Volunteers

HIV Infections

United Kingdom, Kenya
Emory University
International AIDS Vaccine Initiative; Zambia-Emory HIV Research Project

Completed

Zambia SiVET MMR Tdap-IPV (SiVET)

High Risk for HIV

Zambia
Swiss Tropical & Public Health Institute
University of Zurich; University Hospital, Basel, Switzerland; University of... and other collaborators

Active, not recruiting

Tolerability of Lopinavir Versus Dolutegravir for Children and Adolescents Living With HIV (LoDoCA)

HIV

Lesotho
International AIDS Vaccine Initiative
Beth Israel Deaconess Medical Center; University of Rochester

Completed

Trial of the Safety and Immunogenicity of an Oral, Replicating Ad26 Vectored HIV-1 Vaccine

HIV

United States
Novartis Pharmaceuticals
International Maternal Pediatric Adolescent AIDS Clinical Trials Group; Southwest...

Terminated

Single-dose Study to Assess Efficacy of Canakinumab (ACZ885) in Patients With Active Juvenile Idiopathic Arthritis (SJIA) (β-SPECIFIC 1)

Systemic Juvenile Idiopathic Arthritis

United States, Argentina, Canada, Switzerland, Germany, United Kingdom, Israel, South Africa, Belgium, Greece, Italy, Spain, France, Brazil, Turkey, Hungary, Poland, Norway, Sweden, Netherlands, Peru, Denmark
National Institute of Allergy and Infectious Diseases...
International AIDS Vaccine Initiative

Withdrawn

Safety of and Immune Response to an HIV DNA Plasmid Vaccine Followed by HIV Adenoviral Vector Vaccine in Healthy African Adults

HIV Infections
International AIDS Vaccine Initiative
Brigham and Women's Hospital; Fred Hutchinson Cancer Center; Rockefeller University

Active, not recruiting

Safety and Pharmacokinetics of the Combination Broadly Neutralizing Antibodies, 3BNC117-LS-J and 10-1074-LS-J, in Healthy American and African Adults

HIV-1-infection

United States, Uganda, Kenya, Rwanda, South Africa
International AIDS Vaccine Initiative
GlaxoSmithKline; George Washington University; Amsterdam UMC, location VUmc; Rockefeller...

Active, not recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein BG505 SOSIP.GT1.1 gp140 Vaccine, Adjuvanted in Healthy, HIV-uninfected Adults

HIV Infections

United States, Netherlands
International AIDS Vaccine Initiative
Children's Hospital of Philadelphia; Nationwide Children's Hospital; Targeted...

Completed

Safety and Immunogenicity Study of tgAAC09, a Gag-PR-RT AAV HIV Vaccine (A001)

HIV Infection

Belgium, Germany, India
International AIDS Vaccine Initiative
3M; Polymun Scientific GmbH; Access to Advanced Health Institute (AAHI)

Not yet recruiting

A Study to Evaluate the Safety and Immunogenicity of 2 Doses of 100µg BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, Given to a Population of Adults Who Have Received 3 Doses of 300µg BG505 SOSIP.GT1.1 gp140 Vaccine, Adjuvanted

Hiv

Netherlands
International AIDS Vaccine Initiative
ModernaTX, Inc.; AURUM Tembisa Clinical Research; Center for Family Health Research

Active, not recruiting

A Study to Evaluate the Safety and Immunogenicity of eOD-GT8 60mer mRNA Vaccine (mRNA-1644)

HIV-1-infection

Rwanda, South Africa
Rockefeller University
Bill and Melinda Gates Foundation; International AIDS Vaccine Initiative; Aaron... and other collaborators

Completed

Study of a Potential Preventive Vaccine Against HIV in Healthy Volunteers (ADVAX-EP)

HIV Infections

United States
International AIDS Vaccine Initiative
Massachusetts General Hospital; GlaxoSmithKline; Fred Hutchinson Cancer Research... and other collaborators

Completed

A Randomized, Double-blinded, Placebo-controlled, Dose-escalation Phase 1 Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV Envelope Protein BG505 SOSIP.664 gp140 Vaccine, Adjuvanted, in Healthy, HIV-1 Uninfected Adults

HIV Infections

United States, Kenya
International AIDS Vaccine Initiative
National Institute of Allergy and Infectious Diseases (NIAID); Children's Hospital...

Unknown

A Phase 1, Randomized, Blinded, Dose-escalation Study of rAAV1-PG9DP Recombinant AAV Vector Coding for PG9 Antibody in Healthy Male Adults.

HIV Infections

United Kingdom
Elizabeth Glaser Pediatric AIDS Foundation
United States Agency for International Development (USAID); Ministry of Health...

Completed

Family-centered HIV Care, Viral Suppression and Retention in HIV-positive Children, Swaziland (FAM-CARE)

HIV Infections

Swaziland
National Institute of Allergy and Infectious Diseases...
International Maternal Pediatric Adolescent AIDS Clinical Trials Group

Withdrawn

Safety and Tolerability of a Therapeutic DNA Dendritic Cell Vaccine in HIV-Infected Children, Adolescents, and Young Adults

HIV Infections
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

IMPAACT P1058A: Pharmacokinetic Effects of New Antiretroviral Drugs on Children, Adolescents and Young Adults

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
International Maternal Pediatric Adolescent AIDS Clinical Trials Group

Completed

Safety of and Immune Response to a Meningitis Vaccine in HIV-Infected Children and Youth

HIV Infections | Meningitis

United States, Puerto Rico
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

IMPAACT P1074: Long-Term Outcomes in HIV-Infected Infants, Children, and Adolescents

HIV Infections

United States, Puerto Rico
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Laboratory Study of Licensed H1N1 Influenza Vaccines in HIV-1 Perinatally Infected Children and Youth

Influenza | HIV-1 Infection | Flu | H1N1

United States, Puerto Rico
EuroVacc Foundation
Centre Hospitalier Universitaire Vaudois; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Completed

Evaluation of the Effect of Late Boost on HIV-uninfected Vaccines From EV06 Trial

HIV/AIDS

Uganda
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Comprehensive... and other collaborators

Terminated

Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers With HIV

HIV Infection | Tuberculosis | Pneumocystis Jiroveci Pneumonia

Botswana, South Africa
David Ho
Bill and Melinda Gates Foundation; International AIDS Vaccine Initiative; The...

Completed

10E8.4/iMab Bispecific Antibody in HIV-uninfected and HIV-infected Adults

HIV-1-infection

United States
Elizabeth Glaser Pediatric AIDS Foundation
Tanzania Ministry of Health, Community Development, Gender, Elderly and Children and other collaborators

Completed

Evaluating an HIV Risk Screening Tool for Orphans and Vulnerable Children in Tanzania

Pediatric HIV Infection

Tanzania
University of Alabama at Birmingham
United States Agency for International Development (USAID); Elizabeth Glaser...

Completed

A Randomized Trial of IUD Versus Hormonal Contraception in HIV-infected Women in Zambia

HIV Infection | Pregnancy
International AIDS Vaccine Initiative
National Institute of Allergy and Infectious Diseases (NIAID); Access to Advanced...

Not yet recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of a Prophylactic HIV Vaccine Candidate

Hiv
International AIDS Vaccine Initiative
Brigham and Women's Hospital; George Washington University; Redemption Hospital; East-West Medical Research Institute

Active, not recruiting

A Clinical Trial to Evaluate the Safety and Immunogenicity of rVSV∆G-LASV-GPC Vaccine in Adults in Good General Heath

Lassa Fever | Lassa Virus Infection

United States, Liberia
International AIDS Vaccine Initiative
National Institute of Allergy and Infectious Diseases (NIAID); Beth Israel... and other collaborators

Completed

A Phase 1/2a Study of PGT121, VRC07-523LS and PGDM1400 Monoclonal Antibodies in HIV-uninfected and HIV-infected Adults

HIV/AIDS

United States
EuroVacc Foundation
Medical Research Council; Centre Hospitalier Universitaire Vaudois; MRC/UVRI... and other collaborators

Completed

Safety and Immunogenicity Study of a DNA Vaccine Combined With Protein Vaccine Against HIV/AIDS (EV06)

HIV/AIDS

Uganda
University of Oxford
University of Washington; KEMRI-Wellcome Trust Collaborative Research Program; International AIDS Vaccine Initiative and other collaborators

Completed

Targeted Screening of At-Risk Adults for Acute HIV-1 Infection (AHI)

HIV

Kenya
International AIDS Vaccine Initiative
Beth Israel Deaconess Medical Center; Ragon Institute of MGH, MIT and Harvard; University of Texas Health, Houston AIDS Research Team (HART) and other collaborators

Completed

A Clinical Trial of PGDM1400 and PGT121 and VRC07-523LS Monoclonal Antibodies in HIV-infected and HIV-uninfected Adults

HIV Infections

United States

Clinical Trials Sponsored by Baylor International Pediatric AIDS Initiative

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ukraine

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations