Clinical Trials Sponsored by Beijing Defengrui Biotechnology Co. Ltd

Total 1328 results

Staidson (Beijing) Biopharmaceuticals Co., Ltd
Beijing Defengrui Biotechnology Co. Ltd

Terminated

Efficacy and Safety Study of BDB-001 in Severe COVID-19 With ALI/ARDS

COVID-19 Pneumonia

Spain, Bangladesh, China, India, Indonesia
Staidson (Beijing) Biopharmaceuticals Co., Ltd
Beijing Defengrui Biotechnology Co. Ltd

Terminated

A Safety and Tolerability Study of BDB-001 in Mild, Moderate COVID-19 Patients

COVID-19

China
Staidson (Beijing) Biopharmaceuticals Co., Ltd
Beijing Defengrei Biotechnology Co.,Ltd

Completed

Safety and Tolerability of BDB-001 Injection in Healthy Subjects

Healthy

China
Staidson (Beijing) Biopharmaceuticals Co., Ltd
Beijing Defengrei Biotechnology Co.,Ltd

Completed

Tolerability and Safety of BDB-001 Injection in Healthy Subjects

Healthy

China
Beijing Kejing Biotechnology Co., Ltd.
Beijing Kejing Biotechnology Corp.

Withdrawn

An Exploratory Clinical Study to Evaluate the Safety and Efficacy of NK Cells (Combined With Standard Therapy) in the Treatment of Solid Tumor Patients (CCT-ANK-11)

Solid Tumors (Pancreatic Cancer, Esophageal Cancer, Gastric Cancer, Cholangiocarcinoma, Lung Cancer and Ovarian Cancer)

China
Beijing Minhai Biotechnology Co., Ltd

Recruiting

A Phase 3 Study to Evaluate the Immunogenicity and Safety of Minhai's PCV13-DT/TT Vaccine As Compared to Pfizer's PCV13 Vaccine

Pneumococcal Infections | Pneumococcal Vaccines

Indonesia
Beijing Luzhu Biotechnology Co., Ltd.

Recruiting

A Phase Ⅲ Clinical Study to Evaluate Protective Efficacy and Safety of a Recombinant Herpes Zoster Vaccine

Herpes Zoster | Vaccine-Preventable Diseases

China
Beijing Minhai Biotechnology Co., Ltd

Completed

Immunogenicity and Safety of Group A, C, Y and W135 Meningococcal Polysaccharide Vaccine

Meningitis

China
Beijing Luzhu Biotechnology Co., Ltd.

Recruiting

A Study to Evaluate Safety and Tolerability of a Recombinant Herpes Zoster Vaccine

Herpes Zoster | Vaccine-Preventable Diseases

United States
Beijing Minhai Biotechnology Co., Ltd

Completed

A Study to Evaluate Persistence of Immunity of PCV13 in Healthy Population Aged 2 Months，7 Months-5 Years

Pneumonia

China
Beijing Minhai Biotechnology Co., Ltd

Unknown

Safety and Immunogenicity of Haemophilus Influenzae Type b Conjugate Vaccine，Freeze-dried

Haemophilus Influenzae Type b Infections

China
Beijing Biohealthcare Biotechnology Co.,Ltd

Unknown

DC-CIK In Combination With Chemotherapy ( Gio / Oxaliplatin or Cisplatin ) Versus First-line Chemotherapy for Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma Randomized Controlled Phase II Clinical Study of Treatment

Gastric Cancer

China
Beijing Minhai Biotechnology Co., Ltd

Completed

A Study to Evaluate Safety and Immunogenicity of Sequential Vaccination of Sabin Inactivated Poliomyelitis Vaccine (Vero Cell) and Live Attenuated Poliomyelitis Vaccine in Healthy 2-month-old Infants

Poliomyelitis

China
Beijing Viroad Biotechnology Co., Ltd.

Unknown

The Detection of Circulating Tumor Cells (CTCs) in Breast Cancer With a Novel in Vivo Device

Circulating Tumor Cells.Breast

China
Beijing Biohealthcare Biotechnology Co.,Ltd

Unknown

Pilot Study of Anti-CD20-CAR-engineered T Cells in Patients With Chemotherapy Resistant or Refractory CD20+ Lymphoma

Lymphoma, B-Cell

China
Beijing Minhai Biotechnology Co., Ltd

Completed

Immunogenicity and Safety of Meningococcal (A, C, Y and W135) Conjugate Vaccine

Meningitis

China
Staidson (Beijing) Biopharmaceuticals Co., Ltd
Beijing Sanuo Jiayi Biotechnology Co. LTD

Terminated

To Evaluate the Safety and Efficacy of STSG-0002 Injection in Patients With Chronic Hepatitis B

Chronic Hepatitis b

China
Staidson (Beijing) Biopharmaceuticals Co., Ltd
Beijing Sanuo Jiayi Biotechnology Co. LTD

Terminated

Evaluate the Safety and Efficacy of STSG-0002 Injection in Patients With Chronic Hepatitis B

Chronic Hepatitis b

China
LanZhou University
Beigene (Beijing) Biotechnology Co., Ltd

Not yet recruiting

Zanubrutinib in Maintenance Therapy of DLBCL Patients With Initial Remission

Diffuse Large B-cell Lymphoma (DLBCL)

China
RenJi Hospital
Beijing Viroad Biotechnology Co., Ltd.

Completed

CTC in Predicting Neoadjuvant Chemotherapy Among LABC Patients: a Single-center, Prospective, Exploratory Clinical Trial (CTCNeoBC)

Locally Advanced Breast Cancer | Circulating Tumor Cell

China
Beijing Sanbo Brain Hospital
Marino Biotechnology Co., Ltd.

Unknown

Pilot Study of Autologous Chimeric Switch Receptor Modified T Cells in Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme

China
Shenzhen Kangtai Biological Products Co., LTD
Beijing Minhai Biotechnology Co., Ltd

Not yet recruiting

A Study to Evaluate the Efficacy, Safety and Immunogenicity of SARS-CoV-2 Vaccine (Vero Cells), Inactivated in Healthy Adults Aged 18 Years and Older (COVID-19)

COVID-19
Peking University
Yingkai Saiwei（Beijing）Biotechnology Co., Ltd

Not yet recruiting

Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Solid Tumor

Advanced Solid Tumor

China
Beijing Sanbo Brain Hospital
Marino Biotechnology Co., Ltd.

Unknown

Pilot Study of Autologous Anti-EGFRvIII CAR T Cells in Recurrent Glioblastoma Multiforme

Glioblastoma Multiforme

China
Shanghai Zerun Biotechnology Co.,Ltd
Walvax Biotechnology Co., Ltd.

Active, not recruiting

Safety and Immunogenicity of Recombinant SARS-CoV-2 Spike Protein Vaccine (CHO Cell) for the Prevention of COVID-19

COVID-19

China
Shanghai Zerun Biotechnology Co.,Ltd
Walvax Biotechnology Co., Ltd.

Active, not recruiting

Phase I Clinical Trial of Recombinant SARS-CoV-2 Spike Protein Vaccine (CHO Cell) for the Prevention of COVID-19

COVID-19

China
Shanghai Zerun Biotechnology Co.,Ltd
Walvax Biotechnology Co., Ltd.

Active, not recruiting

Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9

Cervical Cancer | Papillomavirus Infections | CIN | Genital Wart | VIN

China
Shanghai Zerun Biotechnology Co.,Ltd
Walvax Biotechnology Co., Ltd.

Active, not recruiting

Phase II Clinical Trial of Recombinant SARS-CoV-2 Spike Protein Vaccine (CHO Cell) for the Prevention of COVID-19

COVID-19

China
Beijing Tsinghua Chang Gung Hospital
China Immunotech (Beijing) Biotechnology Co., Ltd.

Suspended

GPC3-CAR-T Cells for the Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Wuhan Rhegen Biotechnology Co., Ltd.
Shenzhen Rhegen Biotechnology Co., Ltd.; Wuhan Recogen Biotechnology Co., Ltd.

Withdrawn

A Phase 1, Randomised, Double-blinded, Placebo-controlled, Dose-escalation Study to Evaluate the Safety and Immunogenicity of RH109 as Booster

COVID-19 Pandemic
Xijing Hospital
Xi'An Yufan Biotechnology Co.,Ltd

Recruiting

CRISPR (HPK1) Edited CD19-specific CAR-T Cells (XYF19 CAR-T Cells) for CD19+ Leukemia or Lymphoma.

Lymphoma, B-Cell | CD19 Positive | Leukemia Lymphocytic Acute (ALL) in Relapse | Leukemia Lymphocytic Acute (All) Refractory

China
Fujian Cancer Hospital
China Immunotech (Beijing) Biotechnology Co., Ltd.

Unknown

EBV-TCR-T（YT-E001）for Patients With EBV-positive Recurrent or Metastatic NPC

Nasopharyngeal Carcinoma

China
Walvax Biotechnology Co., Ltd.
Abogen Biosciences Co. Ltd.; Yuxi Walvax Biotechnology Co., Ltd.

Recruiting

A Phase III Clinical Study of a SARS-CoV-2 Messenger Ribonucleic Acid (mRNA) Vaccine Candidate Against COVID-19 in Population Aged 18 Years and Above

COVID-19 | SARS-CoV-2

Indonesia, Mexico
Corregene Biotechnology Co., Ltd

Not yet recruiting

KRAS-Specific Autologous TCR-T Cell Therapy for KRAS Mutation in Advanced Solid Tumors

Non-small Cell Lung Cancer (NSCLC) | Colorectal | Pancreatic
Avistone Biotechnology Co., Ltd.

Recruiting

Vebreltinib Plus PLB1004 as the First-line Therapy for Patients With EGFRm+/MET+ Locally Advanced or Metastatic NSCLC.

Non-Small-Cell Lung Cancer

China
Corregene Biotechnology Co., Ltd

Not yet recruiting

CRTE7A2-01 TCR-T Cells for HPV-16 Positive Advanced Cancers

Cervical Cancer | Anal Cancer | Head and Neck Cancers | Other Solid Tumors
Sclnow Biotechnology Co., Ltd.

Not yet recruiting

Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia

Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia Type 6
Sclnow Biotechnology Co., Ltd.

Suspended

SCLife®-UT hUC-MSCs Advanced Therapy Medicinal Products (hUC-MSCs ATMPs) for Patients With Thin Endometrial Infertility

Infertility, Female

China
Sclnow Biotechnology Co., Ltd.

Suspended

Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period.

Cerebral Infarction

China
Walvax Biotechnology Co., Ltd.

Active, not recruiting

A Phase 3 Study to Evaluate the Immunogenicity and Safety of Walvax's PCV13-TT as Compared to Pfizer's PCV13

Pneumococcal Disease, Invasive

Indonesia
Genovate Biotechnology Co., Ltd.,

Completed

BE Study of Once Daily PMR Compared to Twice Daily Cilostazol Tablets in Healthy Volunteers

Intermittent Claudication

United States
TaiGen Biotechnology Co., Ltd.

Completed

Oral Nemonoxacin in Treating Elderly Patients With CAP

Community-acquired Pneumonia

Taiwan
Genovate Biotechnology Co., Ltd.,

Completed

Pharmacokinetic Study of Once Daily PMR Compared to Twice Daily Cilostazol IR Tablets in Healthy Volunteers

Intermittent Claudication

United States
TaiGen Biotechnology Co., Ltd.

Completed

A Study Evaluating the Effect of a Single-dose Oral Administration of Nemonoxacin Capsule on QTc Intervals and Heart Rhythms of Healthy Subjects and the Influence of Food Intake on QTc Intervals and Pharmacokinetic Characteristics

Healthy Volunteers
Genovate Biotechnology Co., Ltd.,

Completed

Mycophenolate Mofetil Versus Azathioprine for Maintenance Therapy of Lupus Nephritis

Lupus Nephritis
TaiGen Biotechnology Co., Ltd.

Completed

Clinical Study on Oral Nemonoxacin Malate Capsules

Healthy Volunteers

China
Cellonis Biotechnology Co. Ltd.

Unknown

Stem Cell Therapy for Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus

China
Genovate Biotechnology Co., Ltd.,

Completed

Type 2 Diabetes Patients Switched From Sulfonylurea With Metformin to Glyburide/Metformin Combination Tablet

Type 2 Diabetes Mellitus

Taiwan
China Immunotech (Beijing) Biotechnology Co., Ltd.
Shanghai Changzheng Hospital

Recruiting

An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease

Systemic Lupus Erythematosus | Systemic Sclerosis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Sjogren's Syndrome | Antiphospholipid Syndrome | Inflammatory Myopathy

China
Wuhan Union Hospital, China
Eureka(Beijing) Biotechnology Co., Ltd.

Active, not recruiting

ET019003-T Cells in Relapsed/Refractory CD19+ B-Cell Leukemia and Lymphoma

Lymphoma | Leukemia

China

Clinical Trials Sponsored by Beijing Defengrui Biotechnology Co. Ltd

Sponsors and Collaborators

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CROs in Qatar

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