Clinical Trials Sponsored by Brain Tumour Program

Total 92 results

Pediatric Brain Tumor Consortium

Active, not recruiting

Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma (PBTC-047)

Glioma

United States
The Hospital for Sick Children
Pediatric Oncology Group of Ontario; Brain Tumour Program

Unknown

Weekly Vinblastine for Chemotherapy Naive Children With Progressive Low Grade Glioma (PLGGs)

Glioma

Canada
University of Florida
American Brain Tumor Association

Withdrawn

Peptide Vaccine for Glioblastoma Against Cytomegalovirus Antigens (PERFORMANCE)

Glioblastoma
Hoffmann-La Roche
Pediatric Brain Tumor Consortium

Completed

A Study of Capecitabine (Xeloda®) and Concomitant Radiation Therapy in Children With Newly Diagnosed Brainstem Gliomas

Brainstem Glioma

United States
Duke University
National Brain Tumor Foundation(NBTF)

Terminated

Coping With High Grade Glioma

Glioma

United States
Sunnybrook Health Sciences Centre
Brain Tumour Foundation of Canada

Completed

Mindfulness-Based Therapy for Brain Tumour Survivors

Depressive Symptoms | Brain Tumour | Survivors

Canada
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Peginterferon Alfa-2b in Younger Patients With Craniopharyngioma That is Recurrent or Cannot Be Removed By Surgery

Childhood Craniopharyngioma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Glioblastoma | Gliosarcoma | Ependymoma | Anaplastic Astrocytoma | Oligodendroglioma | Anaplastic Ependymoma | Giant Cell Glioblastoma | Astrocytoma, Grade II | Brainstem Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors

Brain and Central Nervous System Tumors | Neuroblastoma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Genetic Study of Brain Tumors in Young Children

Central Nervous System Tumor, Pediatric

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
University College, London
Cancer Research UK; The Brain Tumour Charity

Completed

Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases (HIPPO)

Brain Metastases

United Kingdom
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Atypical Teratoid/Rhabdoid Tumor | Refractory Diffuse Intrinsic Pontine Glioma | CNS Embryonal Tumor, Not Otherwise Specified

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors

Glioblastoma | Gliosarcoma | Medulloblastoma | Anaplastic Astrocytoma | Choroid Plexus Neoplasms | Anaplastic Oligodendroglioma | Giant Cell Glioblastoma | Neuroectodermal Tumor, Primitive | Brainstem Tumors | Teratoid Tumor, Atypical

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High-Grade Glioma

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Brain and Central Nervous System Tumors | Carcinoma of Unknown Primary

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or Atypical Teratoid Rhabdoid Tumor

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer

Sarcoma | Lymphoma | Leukemia | Brain and Central Nervous System Tumors | Metastatic Cancer | Retinoblastoma | Childhood Germ Cell Tumor

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Recurrent Childhood Medulloblastoma | Childhood Choroid Plexus Tumor | Childhood Ependymoblastoma | Childhood Grade III Meningioma | Childhood High-grade Cerebellar Astrocytoma | Childhood High-grade Cerebral Astrocytoma | Childhood Medulloepithelioma | Recurrent Childhood Anaplastic Astrocytoma | Recurrent... and other conditions

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Withdrawn

Biomarkers in Blood Samples From Young Patients With Newly Diagnosed Brain Tumors Undergoing Standard Radiation Therapy and Chemotherapy

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery

Recurrent Childhood Anaplastic Astrocytoma | Recurrent Childhood Anaplastic Oligoastrocytoma | Recurrent Childhood Anaplastic Oligodendroglioma | Recurrent Childhood Giant Cell Glioblastoma | Recurrent Childhood Glioblastoma | Recurrent Childhood Gliomatosis Cerebri | Recurrent Childhood Gliosarcoma

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Withdrawn

Studying Cerebrospinal Fluid Proteins and Angiogenesis Proteins in Young Patients With Newly Diagnosed Central Nervous System Tumors

Brain and Central Nervous System Tumors

United States
Baylor College of Medicine
Pediatric Brain Tumor Consortium

Completed

Karenitecin in Pediatric Patients With Refractory or Recurrent Solid Tumors N10010) (KTN10010)

Solid Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Genetic Study of Newly Diagnosed Central Nervous System Tumors in Young Children

Central Nervous System Embryonal Neoplasm

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Withdrawn

Immunotoxin Therapy in Treating Children With Recurrent Malignant Gliomas

Brain and Central Nervous System Tumors
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

SU5416 in Treating Children With Recurrent or Progressive Brain Tumors

Brain and Central Nervous System Tumors

United States
Memorial Sloan Kettering Cancer Center
Pediatric Brain Tumor Consortium

Terminated

A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia

Fanconi Anemia | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML)

United States
Marquette General Health System
Upper Michigan Brain Tumor Center

Withdrawn

Vascular Endothelial Growth Factor (VEGF) Levels in Brain Tumor Patients

Glioma | Meningioma

United States
University of Birmingham
University of Leeds; Jazz Pharmaceuticals; The Brain Tumour Charity

Recruiting

ARISTOCRAT: Blinded Trial of Temozolomide +/- Cannabinoids (ARISTOCRAT)

Glioblastoma | Brain Tumor | Cannabis | Brain Tumor, Recurrent

United Kingdom
Day One Biopharmaceuticals, Inc.
SIOPe Brain Tumor Group LOGGIC Consortium

Recruiting

DAY101 vs. Standard of Care Chemotherapy in Pediatric Patients With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

Low-grade Glioma

United States, Korea, Republic of, France, Germany, Spain, United Kingdom, Belgium, Denmark, Canada, Italy, Finland, Australia, Ireland, Switzerland, Netherlands, Czechia, Greece, New Zealand, Slovenia, Sweden, Hungary, Singapore, A... and more
M.D. Anderson Cancer Center
EMD Serono; Brain Tumor Trials Collaborative

Withdrawn

Ph II Cilengitide Plus Bevacizumab for Recurrent Glioblastoma (GBM)

Glioblastoma
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); PTC Therapeutics

Completed

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

Brain and Central Nervous System Tumors

United States
Daniel Landi
Pediatric Brain Tumor Foundation; Annias Immunotherapeutics, Inc.

Active, not recruiting

PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma (PRiME)

Malignant Glioma | Recurrent Medulloblastoma | Recurrent Brain Tumor, Childhood

United States
Susan Chang
American Brain Tumor Association

Terminated

68Ga-citrate PET/MR Imaging for Glioma

Glioma

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

Chemotherapy in Treating Patients With Progressive or Recurrent Brain Tumors

Brain and Central Nervous System Tumors

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

Carmustine Implants in Treating Patients With Brain Metastases

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer

United States
Children's Oncology Group
National Cancer Institute (NCI); Pediatric Brain Tumor Consortium

Active, not recruiting

Pilot Study to Enable Electronic Laboratory Data Transfer From Participating Institutions to MediData/RAVE

Accurate and Complete Data Acquisition for Clinical Trials

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

Pharmacologic Study of Methotrexate in Patients Undergoing Stereotactic Biopsy for Recurrent High-Grade Glioma

Brain and Central Nervous System Tumors
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

Immunotoxin Therapy in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

Irinotecan in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

Radiation Therapy in Treating Patients With Progressive or Recurrent Malignant Brain Tumors

Brain and Central Nervous System Tumors

United States
Johns Hopkins All Children's Hospital
The V Foundation; Brain Tumor Alliance

Completed

Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors

Central Nervous System Tumors

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

EMD 121974 in Treating Patients With Progressive or Recurrent Glioma

Brain and Central Nervous System Tumors

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

Methotrexate and Thiotepa in Treating Patients With Newly Diagnosed Primary CNS Lymphoma

Lymphoma

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

COL-3 in Treating Patients With Progressive or Recurrent Brain Tumors

Brain and Central Nervous System Tumors

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

Procarbazine in Treating Patients With Recurrent Brain Tumor

Brain and Central Nervous System Tumors

United States

Clinical Trials Sponsored by Brain Tumour Program

Sponsors and Collaborators

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