Clinical Trials Sponsored by CRL

Total 1111 results

Biokosmes Srl
Opera CRO, a TIGERMED Group Company

Completed

Open-label Trial Evaluating Four Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste, and Mouthwash

Oral Hygiene | Dental Plaque | Toothbrushing

Italy
Nekkar Lab Srl
Opera CRO, a TIGERMED Group Company

Recruiting

Study to Evaluate the Performance and Safety of the MARIAL® in Association With PPI Versus PPI Alone (GENYAL®)

Gastroesophageal Reflux Disease (GERD)

Italy, Romania
Iuppa Industriale Srl
Opera CRO, a TIGERMED Group Company

Completed

Food Supplement Physiomanna® Baby in Pediatric Patients

Irritable Bowel Syndrome Characterized by Constipation

Romania
AM-Pharma
CRM Biometrics GmbH; Sintesi Research Srl; Vigilex BV

Completed

Safety/Efficacy Study of Bovine Intestinal Alkaline Phosphatase in Patients With Moderate to Severe Ulcerative Colitis

Ulcerative Colitis

Czech Republic, Italy
MicroPort CRM
Sorin CRM

Unknown

Clinical Trial of the SonRtip Lead and Automatic AV-VV Optimization Algorithm in the PARADYM RF SonR CRT-D (RESPOND-CRT)

Heart Failure NYHA Class III and Ambulatory IV

United States, Spain, United Kingdom, Germany, Italy, Australia, Netherlands, Portugal, France, Austria, Switzerland, Slovenia
MicroPort CRM
Sorin CRM

Unknown

Continued Access Clinical Trial of the SonRtip Lead and Automatic AV-VV Optimization Algorithm in the PARADYM RF SonR CRT-D (RESPOND-CAS)

Heart Failure (NYHA Class III and Ambulatory IV)

United States
CSL Behring
CSL Plasma

Completed

Rabies Immune Plasma Booster Study

Rabies

United States
Egas Moniz - Cooperativa de Ensino Superior, CRL

Completed

Study of the Fluid Intake Effect During Labour

Labor Complication

Portugal
Egas Moniz - Cooperativa de Ensino Superior, CRL

Completed

Effect of Aqueous Cinnamon Extract on the Postprandial Glycaemia Levels in Type 2 Diabetes Mellitus

Type 2 Diabetes
Egas Moniz - Cooperativa de Ensino Superior, CRL

Completed

Effect of Baobab Fruit on Postprandial Glycaemia in Healthy Adults

Hyperglycemia, Postprandial

Portugal
Genzyme, a Sanofi Company
CRL/Medinet

Terminated

Severe Renal Disease Study in Fabry Patients Treated With Fabrazyme

Fabry Disease | Chronic Kidney Disease, Stage IV (Severe)

United States
Egas Moniz - Cooperativa de Ensino Superior, CRL

Completed

Effect of Ginger Extract on Postprandial Glycaemia of Healthy Adults and Its Antioxidant Properties

Hyperglycemia, Postprandial

Portugal
Complife Italia Srl
Macrofarm Srl; Icim International Srl

Completed

EValuation of the Antioxidant and Anti-inflammatory Capacity of Nutraceutical IMMU·SYSTEM Food Supplement (EVAANIS) (EVAANIS)

Oxidative Stress

Italy
Mundipharma Pharmaceuticals srl
Bioikos Ambiente Srl

Completed

Trauma Acute Pain Treatment With Methoxyflurane Vaporized (PENTHROX®): Efficacy and Safety Study (MEDITA) (MEDITA)

Acute Traumatic Pain

Italy
CSL Behring

Recruiting

Efficacy and Safety of CSL222 (Etranacogene Dezaparvovec) Gene Therapy in Adults With Hemophilia B With Pretreatment Adeno-associated Virus Serotype 5 (AAV5) Neutralizing Antibodies (Nabs)

Hemophilia B

United States, Canada, Israel
MicroPort CRM

Not yet recruiting

PoSt-market Assessment on Safety and Performance of J-sHAPed xFINE Lead (SHAPE)

Bradycardia
MicroPort CRM

Recruiting

Clinical Assessment of Essential Remote Monitoring Functions in Pacemakers (CALLIOPE)

Bradycardia | Remote Monitoring

France, Belgium, Germany, Portugal, Spain, United Kingdom, Austria, Netherlands
CSL Behring

Recruiting

Observatory of Patients With Haemophilia B Treated by IdElvion® (OrPHEe)

Haemophilia B

France
MicroPort CRM

Recruiting

Collection of SPOT EGMs And inTra-Cardiac Impedance for Atrio-ventricUlar and inteR-ventricular Delays optimizatioN (SATURN)

Heart Failure

France
CSL Behring

Recruiting

The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-Versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant (MODULAATE)

Acute-graft-versus-host Disease

United States, Korea, Republic of, Spain, Australia, Germany, Italy, Turkey, Japan
CSL Behring

Recruiting

Two Dose Levels of Privigen in Pediatric CIDP

Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

United States
CSL Behring

Active, not recruiting

Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis

End Stage Kidney Disease | Atherosclerotic Cardiovascular Disease

United States, Australia, Belgium, Canada, Germany
CSL Behring

Completed

Study to Investigate CSL112 in Subjects With Acute Coronary Syndrome (AEGIS-II)

Acute Coronary Syndrome

United States, Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, Colombia, Croatia, Czechia, Denmark, Estonia, Finland, France, Georgia, Germany, Greece, Hong Kong, Hungary, Israel, Italy, Japan, Korea, Republic of, Latvi... and more
CSL Behring

Completed

Registry of Patients With Von WilLEbrand Disease Treated With Voncento® (OPALE)

Von Willebrand Disease

France
CSL Behring

Active, not recruiting

Study of AAV5-hFIX in Severe or Moderately Severe Haemophilia B

Hemophilia B

Netherlands, Germany
CSL Behring

Enrolling by invitation

Long-term Follow-up Study of Male Adults With Hemophilia B Previously Treated With Etranacogene Dezaparvovec (CSL222)

Hemophilia B

United States
Idego srl

Completed

Golden Age: Virtual Reality and Mindfulness

Healthy Lifestyle | Psychological Wellbeing

Italy
CSL Behring

Completed

A Clinical Study to Test the Safety, Exposure, and Pharmacodynamic Markers of CSL311 in Patients With Mild-to-moderate Asthma and in Healthy Volunteers

Asthma

United Kingdom, Germany
CSL Behring

Completed

Effects of CSL324 in the Lung After Segmental Challenge

Healthy Volunteers

Germany
Endostart srl

Completed

Endorail in Long Lasting Colonoscopy

Colonoscopy | Incomplete Colonoscopy

Belgium, Germany, Italy
CSL Behring

Completed

CSL312 (Garadacimab) in the Prevention of Hereditary Angioedema Attacks

Hereditary Angioedema

United States, Germany, Japan, Hungary, Canada, Netherlands, Israel
MicroPort CRM

Completed

Safety and Electrical Performances of XFINE Leads (PERSEPOLIS)

Bradycardia

France, Italy, Spain, United Kingdom, Portugal
Nouscom SRL

Active, not recruiting

Nous-PEV: a Novel Immunotherapy for Lung Cancer and Melanoma

Melanoma (Skin) | Non-Small-Cell Lung Carcinoma

Belgium, Spain, United Kingdom
CSL Behring

Completed

A Study to Investigate CSL312 in Subjects With Hereditary Angioedema (HAE)

Hereditary Angioedema

Canada, Australia, Germany, United States, Israel
CSL Behring

Completed

Pharmacokinetics and Safety of Subcutaneous CSL324 in Healthy Japanese and White Subjects

Healthy

Australia
CSL Behring

Terminated

Efficacy and Safety of Human Plasma-derived C1-esterase Inhibitor as add-on to Standard of Care for the Treatment of Refractory Antibody Mediated Rejection (AMR) in Adult Renal Transplant Recipients

Antibody-mediated Rejection

United States, Spain, France, Netherlands, United Kingdom, Belgium, Germany
CSL Behring

Completed

A Safety and Efficacy Extension Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Patients With Hemophilia B

Hemophilia B

United States, Australia, Japan, France, Philippines, Spain, Czechia, Israel, Canada, Germany, Austria, Bulgaria, Italy, Malaysia, South Africa
CSL Behring

Terminated

Dose Ranging Study of BMS-945429 in Subjects With Moderate to Severe Crohn's Disease

Crohn's Disease

Germany, India, Korea, Republic of, Taiwan, United States, Hong Kong, Canada, Mexico, Austria, Switzerland, Israel, Italy, France, Poland, Netherlands, Hungary, Czechia, United Kingdom
CSL Behring

Completed

A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.

Acute Myocardial Infarction

United States, Australia, Austria, Bulgaria, Canada, Czechia, Denmark, France, Germany, Hungary, Israel, Italy, Netherlands, Poland, Spain, United Kingdom
CSL Behring

Terminated

Evaluating the Effectiveness of Telemonitoring System in the Management of Patients With CIDP (HELIPAD 1)

Chronic Inflammatory Demyelinating Polyneuropathy

France
NTC srl

Completed

Vaginal and Rectal Colonization of Lactobacillus Crispatus NTCVAG04 Following Oral Administration in Patients With History of Vaginitis/Vaginosis

Vaginitis | Vaginosis

Italy
CSL Behring

Withdrawn

CSL324 in COVID-19

Coronavirus Disease 2019 (COVID-19)
MicroPort CRM

Completed

Clinical and Device Functional Assessment of Real World ICD Patients (CARAT)

Arrythmia | Implantable Cardioverter Defibrillator

Spain, United Kingdom, France, Netherlands, Canada, Czechia, Germany, Italy, Switzerland, Portugal, Austria, Slovakia
CSL Behring

Completed

A Study of CSL112 in Adults With Moderate Renal Impairment and Acute Myocardial Infarction

Acute Myocardial Infarction | Moderate Renal Impairment

United States, Germany, Hungary, Israel, Netherlands
MicroPort CRM

Unknown

Safety and Electrical Performances Evaluation of Navigo Leads Equipped With IS4 Connector (NAVIGATOR)

Arrythmia, Implatable Cardioverter Defibrillation, Lead

Germany, Spain, France, Italy, Netherlands, Portugal
Derming SRL

Completed

Aesthetic Performance of "Profhilo®" Injective Intradermal Treatment for the Neck

Skin Manifestations

Italy
MicroPort CRM

Completed

Assessment of the MRI Solution: KORA 100 and Beflex Pacing Leads System (IKONE)

Bradycardia

France
MicroPort CRM

Completed

Clinical Assessment of the SonR Algorithm in the PARADYM RF SonR CRT-D by Echocardiography (SonR-ECHO)

Heart Failure

Canada
Derming SRL

Completed

Aesthetic Performance of an Injective Treatment for the Skin Roughness and Laxity of Inner Arm and Abdomen

Skin Flaccidity and Roughness of the Abdomen and Inner Arms

Italy
Derming SRL

Completed

Efficacy and Tolerance Evaluation of an Amino Acid Food Supplement

Skin Photoaging

Italy

Clinical Trials Sponsored by CRL

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