Clinical Trials Sponsored by Canadian Institutes of Health Research (CIHR)

Total 4933 results

Western University, Canada
Canadian Institutes of Health Research (CIHR)

Recruiting

The Role of Electrophysiology Testing in Survivors of Unexplained Cardiac Arrest (EPS ARREST)

Sudden Cardiac Death

United States, Canada, Israel
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR)

Enrolling by invitation

Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data Repository (HiRO-HCM)

Cardiomyopathies | Hypertrophic Cardiomyopathy | Hypertrophic Obstructive Cardiomyopathy | Familial Hypertrophic Cardiomyopathy

Canada
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR)

Completed

Non-isotope Based Imaging Modalities vs Technetium-99m Single-Photon Emission Computed Tomography(99mTcSPECT) (MITNECB5)

Myocardial Ischemia

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR); Western University, Canada

Not yet recruiting

Preoperative Rehabilitation and Education Program (PREPS)

Shoulder Arthroplasty | Patient Education | Prehabilitation | Shoulder Arthritis

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR); Western University, Canada

Not yet recruiting

Hands-Up: Exercise and Education Program After a Wrist Fracture

Osteoporosis | Distal Radius Fracture

Canada
Bruyere Research Institute
Canadian Institutes of Health Research (CIHR)

Unknown

The PIP-STOPP Study (PIP-STOPP)

Potentially Inappropriate Prescribing (PIP)
Unity Health Toronto
Canadian Institutes of Health Research (CIHR); Health Canada

Recruiting

Canadian Adaptive Platform Trial of Treatments for COVID-19 in Community Settings (CanTreatCOVID)

COVID-19

Canada
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Colchicine For Prevention of Perioperative Atrial Fibrillation in Patients Undergoing Thoracic Surgery Pilot Study (COP-AF Pilot)

Atrial Fibrillation | Thoracic Surgery

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Impact of Emotional Mimicry and Oxytocin on Frontotemporal Dementia (IEMO)

Frontotemporal Dementia

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Prospective Study Using Hybrid PET/MRI to Evaluate Men With Suspected Recurrence Following Treatment for Prostate Cancer (IGPC-3)

Prostate Cancer

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Unknown

Detecting Radiation-Induced Cardiac Toxicity After Non-Small Cell Lung Cancer Radiotherapy (RICT-LUNG)

Non-small Cell Lung Cancer | Radiation Toxicity

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Activity and Metformin Intervention in Obese Adolescents (REACH)

Obesity | Type 2 Diabetes

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

Narcotic Versus Non-narcotic Medication for Pain Management After Wrist/Hand Fractures

Pain Management | Distal Radius Fracture | Metacarpal Fracture

Canada
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

Aldosterone bloCkade for Health Improvement EValuation in End-stage Renal Disease (ACHIEVE)

Endstage Renal Disease

Canada, Australia, United Kingdom, New Zealand, Malaysia, Brazil, India, Philippines, Uruguay, Ecuador
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Multi-modality Prostate Cancer Image Guided Interventions (IGPC-2)

Prostate Cancer

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Making Mindfulness Matter© in Children With Epilepsy (M3Epilepsy)

Quality of Life | Mindfulness | Epilepsy in Children

Canada
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Prevention of Arrhythmia Device Infection Trial (PADIT)

Arrhythmia

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Effects of Mesna on Homocysteine in Kidney Failure

End Stage Renal Disease

Canada
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Program for the Identification of "Actionable" Atrial Fibrillation in the Family Practice Setting (PIAAF-FP)

Atrial Fibrillation

Canada
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Study of Health Assessment and Risk Evaluation in Aboriginal Peoples Action Toward Obesity Prevention (SHARE-AP Action)

Obesity

Canada
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

Evaluation of A Clinical Diagnostic Test for CRDS (DIAGNOSE CRDS)

Calcium Release Deficiency Syndrome (CRDS)

United States, Israel, Canada, Belgium, Denmark, France, United Kingdom
Population Health Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

HIP Fracture Accelerated Surgical TreaTment And Care tracK 2 Trial (HIP ATTACK-2)

Myocardial Injury | Hip Fractures

United States, Hong Kong, Spain, Canada, Pakistan, South Africa, Netherlands, Malaysia, Finland, Australia, Belgium, Mexico, Nepal, Saudi Arabia, Chile, Italy, Poland, Brazil
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Recruiting

Deep Brain Reorienting in Post-traumatic Stress Disorder

PTSD | Post-traumatic Stress Disorder

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Curcumin to Prevent Complications After Elective Abdominal Aortic Aneurysm (AAA) Repair

Acute Kidney Injury | Abdominal Aortic Aneurysm

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Completed

Body and Brain Exercise for Older Adults With Memory Complaints

Cognitive Ability, General

Canada
Canadian Cancer Trials Group
Canadian Institutes of Health Research (CIHR); Myeloma Canada

Recruiting

Fixed Duration vs Continuous Daratumumab in Transplant Ineligible Older Adults With Newly Diagnosed Multiple Myeloma

Multiple Myeloma

Canada
Western University, Canada
Canadian Institutes of Health Research (CIHR); Health Research Foundation

Completed

Preventing Childhood Obesity: A Two-pronged Approach Starting in Pregnancy and the First Year Postpartum

Childhood Obesity | Dietary Modification | Excessive Weight Gain in Pregnancy With Baby Delivered | Healthy Lifestyle Habits

Canada
Canadian Scleroderma Research Group
Canadian Institutes of Health Research (CIHR)

Unknown

The Small Intestine Bacterial Overgrowth Study Pilot (SIBO)

Systemic Sclerosis | Small Intestinal Bacterial Overgrowth

United States, Australia
Mount Sinai Hospital, Canada
Canadian Institutes of Health Research (CIHR)

Withdrawn

Effect of Probiotic Lactobacilli on Vaginal Flora of Pregnant Women at High Risk for Preterm Delivery

Premature Birth | Bacterial Vaginosis

Canada
Baycrest
Canadian Institutes of Health Research (CIHR)

Completed

Maintaining Independence in Everyday Life Among Seniors With Subjective Cognitive Complaints

Aging

Canada
Mount Sinai Hospital, Canada
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

Peer Champion Support for Hospital Staff During and After the COVID-19 Pandemic

Burnout

Canada
Mount Sinai Hospital, Canada
Canadian Institutes of Health Research (CIHR)

Completed

Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Main Trial) (RESET-IT)

Type 2 Diabetes

Canada
Mount Sinai Hospital, Canada
Canadian Institutes of Health Research (CIHR)

Recruiting

Toronto Gestational Glucose Tolerance Cohort

Type 2 Diabetes, Gestational Diabetes, Pre-diabetes

Canada
Mount Sinai Hospital, Canada
Canadian Institutes of Health Research (CIHR)

Completed

Early Intermittent Intensive Insulin Therapy as an Effective Treatment of Type 2 Diabetes (RESET-IT Pilot Study)

Type 2 Diabetes

Canada
Baycrest
Canadian Institutes of Health Research (CIHR)

Completed

Language Treatment for Progressive Aphasia

Primary Progressive Aphasia | Semantic Dementia | Nonfluent Progressive Aphasia

Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); CIHR Canadian HIV Trials Network

Unknown

The Canadian HIV Quit Smoking Trial: Tackling the Co-morbidities of Depression and Cardiovascular Disease in HIV+ Smokers (CANQUIT)

Smoking Cessation | HIV

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation

Cardiac Allograft Vasculopathy

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

AERIAL Trial: Antiplatelet Therapy in Heart Transplantation

Cardiac Allograft Vasculopathy | Heart Transplant

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

Cardiac Sarcoidosis Randomized Trial (CHASM-CS-RCT)

Sarcoidosis | Cardiac Sarcoidosis

United States, Canada, United Kingdom, Japan
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments (INITIATE)

Nicotine Dependence, Cigarettes | Nicotine Withdrawal

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy

Heart Failure

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Bridge or Continue Coumadin for Device Surgery Randomized Controlled Trial (BRUISECONTROL)

Hematoma

Canada, Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

A Study of 123I-CMICE-013 Radiopharmaceutical in Healthy Volunteers (CMICE)

Coronary Artery Disease

Canada
Mount Sinai Hospital, Canada
Canadian Institutes of Health Research (CIHR); Sunnybrook Research Institute

Recruiting

The Effect of In-utero Exposure to Metformin in 5-11 Year Old Offspring of Mothers in the MiTy Trial (MiTy Tykes)

Diabetes Mellitus, Type 2 | Child Development | Child Obesity | Pregnancy in Diabetic

Canada, Australia
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

Canadian Study of Arterial Inflammation in Patients With Diabetes and Vascular Events: EvaluatioN of Colchicine (CADENCE)

Cardiovascular Diseases | Inflammation | Diabetes | Atherosclerosis

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Rhythm Control - Catheter Ablation With or Without Anti-arrhythmic Drug Control of Maintaining Sinus Rhythm Versus Rate Control With Medical Therapy and/or Atrio-ventricular Junction Ablation and Pacemaker Treatment for Atrial Fibrillation (RAFT-AF)

Heart Failure | Atrial Fibrillation

Canada, Taiwan, Sweden, Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

A Pharmacodynamic Study of a Personalized Strategy for P2Y12 Inhibition Versus Ticagrelor in Reducing Ischemic and Bleeding Risk (RAPID MANAGE)

Acute Coronary Syndrome | Percutaneous Coronary Intervention

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Timing of Coronary Artery Bypass Surgery Among Patients With Acute Coronary Syndromes Initially on Ticagrelor (RAPID CABG)

Acute Coronary Syndrome

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial in Patients With Permanent Atrial Fibrillation (RAFT-PermAF)

Atrial Fibrillation | Heart Disease | Congestive Heart Failure

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Rubidium-82 - An Alternative Radiopharmaceutical for Myocardial Imaging(Rb-ARMI) (Rb-ARMI)

Coronary Artery Disease

Canada

Clinical Trials Sponsored by Canadian Institutes of Health Research (CIHR)

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