Clinical Trials Sponsored by Canadian Heart Research Centre

Total 815 results

Actelion
Canadian Heart Research Centre

Completed

Pulmonary Arterial Hypertension Quality Enhancement Research Initiative Extension Program (PAH QuERI Ext)

Pulmonary Arterial Hypertension

United States, Puerto Rico
Canadian Heart Research Centre
GlaxoSmithKline

Completed

Avandia™ + Amaryl™ or Avandamet™ Compared With Metformin (AVALANCHE™ Study) (AVALANCHE)

Type 2 Diabetes Mellitus

Canada
Canadian Heart Research Centre
Sanofi

Completed

North American Acute Coronary Syndrome (ACS) Reflective III Pilot

Dyslipidemias | Acute Coronary Syndrome

Canada
Actelion
Canadian Heart Research Centre

Completed

Adult Congenital Heart Disease Registry (QuERI)

Pulmonary Arterial Hypertension

United States
Canadian Heart Research Centre
Sanofi

Terminated

Ischemia Driven Enoxaparin Therapy in ACS Presenting as Low Risk (IDEAL) (IDEAL)

Unstable Angina

Canada
Canadian Heart Research Centre
Amgen

Completed

Guidelines Oriented Approach to Lipid Lowering (GOAL) in Canada (GOAL)

Dyslipidemia
Actelion
Canadian Heart Research Centre

Completed

Eisenmenger Quality Enhancement Research Initiative (ES-QuERI)

Pulmonary Arterial Hypertension

United States
Canadian Heart Research Centre
Merck Frosst Canada Ltd.; Schering-Plough

Completed

Guidelines Based Undertaking for Improvement in Dyslipidemia Related Events (GUIDE ) (GUIDE)

Cardiovascular Diseases

Canada
Dr. Anatoly Langer
Amgen

Active, not recruiting

GOAL International QuERI - Protocol CHRC 2019 GOAL INTERNATIONAL (GOAL QuERI)

Dyslipidemia

Kuwait, Mexico, Saudi Arabia, United Arab Emirates
Canadian Heart Research Centre
Canadian Institutes of Health Research (CIHR); Hoffmann-La Roche; Guidant Corporation

Completed

Routine Angioplasty and Stenting After Fibrinolysis for Acute Myocardial Infarction

Myocardial Infarction

Canada
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation... and other collaborators

Completed

Sleep Disorders Managed and Assessed Rapidly in Transient Ischemic Attack (TIA) and In Early Stroke (SMARTIES)

Stroke | Sleep Apnea Syndromes | Restless Legs Syndrome | Ischemic Attack, Transient | Sleep Disorders

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR); Canadian Diabetes Association; Heart and Stroke Foundation of Canada

Completed

Exercise and Technology to Reduce Risk in a Rural Population With Metabolic Syndrome

Metabolic Syndrome X

Canada
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Premature Termination of Resuscitation in Survivors of Cardiac Arrest (PremaTOR)

Cardiac Arrest
Population Health Research Institute
Heart and Stroke Foundation of Canada; Canadian Cardiovascular Society

Completed

Prevalence of Subclinical Atrial Fibrillation in Heart Failure Patients and Its Relationship With Hospital Readmission (PROTECT-HF)

Heart Failure | Atrial Fibrillation

Canada
Ottawa Heart Institute Research Corporation
Bayer; Canadian Institutes of Health Research (CIHR); Biotronik Canada Inc

Active, not recruiting

Optimal Anticoagulation for Higher Risk Patients Post-Catheter Ablation for Atrial Fibrillation Trial (OCEAN)

Stroke | Atrial Fibrillation

Canada, Australia, Germany, Belgium, China, Israel
Ottawa Hospital Research Institute
Heart and Stroke Foundation of Canada; Brain Canada; Canadian Stroke Consortium...

Recruiting

Intensive Cancer Screening After Cryptogenic Stroke (INCOGNITO)

Occult Cancer

Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Survey of Attitudes and Factors Associated With CPR in an Older Population

Cardiac Arrest

Canada
Laval University
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Effects of the Mediterranean Diet on Cardiovascular Risk Profile in Men and Women (ALIMED)-Part 2

Cardiovascular Diseases

Canada
Laval University
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Recruiting

Metabolic Determinants of the Progression of Aortic Stenosis (PROGRESSA)

Aortic Valve Stenosis

Canada
McMaster University
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Perioperative Anticoagulant Use for Surgery Evaluation Study (PAUSE)

Atrial Fibrillation

United States, Canada, Belgium, Greece, Netherlands
Express Collaborative
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Improving the Quality of Cardiopulmonary Resuscitation (CPR) During Pediatric Cardiac Arrest (QCPR)

Cardiac Arrest

United States, Canada, United Kingdom
Laval University
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Effects of the Mediterranean Diet on Cardiovascular Risk Profile in Men and Women (ALIMED)

Cardiovascular Diseases

Canada
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR)

Enrolling by invitation

Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data Repository (HiRO-HCM)

Cardiomyopathies | Hypertrophic Cardiomyopathy | Hypertrophic Obstructive Cardiomyopathy | Familial Hypertrophic Cardiomyopathy

Canada
Montreal Heart Institute
Canadian Institutes of Health Research (CIHR)

Completed

Non-isotope Based Imaging Modalities vs Technetium-99m Single-Photon Emission Computed Tomography(99mTcSPECT) (MITNECB5)

Myocardial Ischemia

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

MARINER Trial: Multiparametric Cardiac PET for CAV Surveillance After Heart Transplantation

Cardiac Allograft Vasculopathy

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

AERIAL Trial: Antiplatelet Therapy in Heart Transplantation

Cardiac Allograft Vasculopathy | Heart Transplant

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

Cardiac Sarcoidosis Randomized Trial (CHASM-CS-RCT)

Sarcoidosis | Cardiac Sarcoidosis

United States, Canada, United Kingdom, Japan
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments (INITIATE)

Nicotine Dependence, Cigarettes | Nicotine Withdrawal

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Ability of L-carnitine to Prevent Heart Damage in Breast Cancer Patients Receiving Anthracycline Chemotherapy

Heart Failure

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Terminated

Bridge or Continue Coumadin for Device Surgery Randomized Controlled Trial (BRUISECONTROL)

Hematoma

Canada, Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

A Study of 123I-CMICE-013 Radiopharmaceutical in Healthy Volunteers (CMICE)

Coronary Artery Disease

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Timing of Coronary Artery Bypass Surgery Among Patients With Acute Coronary Syndromes Initially on Ticagrelor (RAPID CABG)

Acute Coronary Syndrome

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial in Patients With Permanent Atrial Fibrillation (RAFT-PermAF)

Atrial Fibrillation | Heart Disease | Congestive Heart Failure

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Rubidium-82 - An Alternative Radiopharmaceutical for Myocardial Imaging(Rb-ARMI) (Rb-ARMI)

Coronary Artery Disease

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Recruiting

Canadian Study of Arterial Inflammation in Patients With Diabetes and Vascular Events: EvaluatioN of Colchicine (CADENCE)

Cardiovascular Diseases | Inflammation | Diabetes | Atherosclerosis

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

Rhythm Control - Catheter Ablation With or Without Anti-arrhythmic Drug Control of Maintaining Sinus Rhythm Versus Rate Control With Medical Therapy and/or Atrio-ventricular Junction Ablation and Pacemaker Treatment for Atrial Fibrillation (RAFT-AF)

Heart Failure | Atrial Fibrillation

Canada, Taiwan, Sweden, Brazil
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Completed

A Pharmacodynamic Study of a Personalized Strategy for P2Y12 Inhibition Versus Ticagrelor in Reducing Ischemic and Bleeding Risk (RAPID MANAGE)

Acute Coronary Syndrome | Percutaneous Coronary Intervention

Canada
University of Calgary
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Can Adherence to PALS Guidelines be Improved by Team Training of Pediatric Resuscitation Members? (Teams4Kids)

Crisis Resource Management

Canada
Unity Health Toronto
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Withdrawn

Improving Outcomes After Time Sensitive Prehospital Interventions: Rescu Epistry

Stroke | Sepsis | Trauma | Cardiac Arrest

Canada
McGill University Health Centre/Research Institute...
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Recruiting

Conduction System Pacing With Left Bundle Branch Pacing as Compared to Standard Right Ventricular Pacing

Heart Block | Pacemaker DDD

Canada
Ottawa Heart Institute Research Corporation
Genome Canada

Recruiting

Predicting Development of SCAF in Device Patients

Atrial Fibrillation

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR); Medtronic

Completed

Resynchronization/Defibrillation for Ambulatory Heart Failure Trial (RAFT)

Heart Failure, Congestive

Canada, Netherlands, Australia, Turkey, Denmark, Germany, Belgium
University of British Columbia
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Healthy Lifestyles After Stroke - Stroke Coach (StrokeCoach)

Stroke | Vascular Accident, Brain | Stroke, Acute | Cerebrovascular Accident | Cerebral Stroke | Cerebrovascular Stroke | Cerebrovascular Accident, Acute | Apoplexy | CVA | Cerebrovascular Apoplexy

Canada
Mark Eisenberg
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

Zyban as an Effective Smoking Cessation Aid for Patients Following an Acute Coronary Syndrome: The ZESCA Trial (ZESCA)

Myocardial Infarction | Smoking | Acute Coronary Syndrome

Canada, United States, Bangladesh, India, Iran, Islamic Republic of, Pakistan, Tunisia
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Canada

Completed

Family Heart Health Program: Randomized, Controlled Trial (FHHP-RCT)

Coronary Heart Disease

Canada
Marilyn MacKay-Lyons
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation... and other collaborators

Completed

Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-disabling Stroke or Transient Ischemic Attack: A Multi-site RCT (PREVENT)

Transient Ischemic Attack | Non-disabling Stroke

Canada
Ottawa Heart Institute Research Corporation
Heart and Stroke Foundation of Canada

Recruiting

Characterization of Arrhythmia Substrate to Ablate Persistent Atrial Fibrillation (COAST-AF RCT)

Atrial Fibrillation

Canada
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR); Heart and Stroke Foundation...

Completed

PET and Recovery Following Revascularization (PARR 2)

Coronary Artery Disease | Ventricular Dysfunction, Left

Canada
Heart Health Research Center
AstraZeneca

Not yet recruiting

Compare the Impact of Xuezhikang and Atorvastatin on Glucose Metabolism in Dyslipidemia Patients With Prediabetes (XTREME)

Metabolism Disorder, Glucose | Metabolism Disorder, Lipid
University of Waterloo
Ottawa Heart Institute Research Corporation; Canadian Tobacco Control Research...

Completed

Integrating Smoking Cessation Into Routine Primary Care Practice

Smoking Cessation

Clinical Trials Sponsored by Canadian Heart Research Centre

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Oman

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations