Clinical Trials Sponsored by Carla Caffarelli

Total 592 results

Comitato Etico di Area Vasta Sud Est
Carla Caffarelli

Completed

Long Term Efficacy and Tolerability of a Nutraceutical Combination (Red Yeast Rice, Policosanols and Berberine) in Low-moderate Risk Hypercholesterolemic Patients: a Double-blind, Placebo Controlled Study

Hypercholesterolemia
Cardarelli Hospital

Not yet recruiting

High Flow Oxygen Therapy in Patients Undergoing Bronchoscopy Under Sedation (BroncHoFlow)

Respiratory Failure | Hypercapnic Acidosis

Italy
Cardarelli Hospital

Completed

Neoadjuvant Sorafenib Therapy Prior to Laser Ablation for Hepatocellular Carcinoma (LANEX)

Hepatocellular Carcinoma

Italy
Cardarelli Hospital

Recruiting

Impact of High Flow Therapy on Complications Related to Airway Stenting (HiSTENT)

Airway Obstruction | Respiratory Infection | Mucus; Plug

Italy
Cardarelli Hospital

Unknown

Protoves M1® Syrup in Controlling Adverse Event During HIVEC® Instillations

Pain | Bladder Cancer | LUTS
Cardarelli Hospital

Completed

Radiofrequency Versus Laser Ablation for Hepatocellular Carcinoma

Carcinoma, Hepatocellular | Neoplasms, Liver

Italy
Arla Foods

Completed

Supplementation of Infant Formula With Synbiotics

Infant Formula

Poland
Calla IVF Center

Recruiting

Evaluation of the Relationship Between Oxidative Stress and Human Reproduction (OxidStressHR)

Pregnancy | Oxidative Stress | Fertility Disorders | IVF

Romania
Calla IVF Center

Completed

Effect of Immunomodulatory Treatment on IVF (in Vitro Fertilization) Outcomes in Patients With KIR AA Genotype

Immunomodulatory Drugs | Killer-cell Immunoglobulin-like Receptors (KIRs) | KIR Alleles (KIR AA)

Romania
Arla Foods

Completed

Feeding Infant Formula With Added Probiotics and Whey Protein Concentrate

Focus on Healthy Infants

China
Karla Andrea Arias Varela

Completed

Treatment of Osteoarthrosis of the Knee With Platelet Rich Plasma, Comparative Study With Hyaluronic Acid

Osteoarthritis

Costa Rica
Carna Biosciences, Inc.

Recruiting

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

Follicular Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Small Lymphocytic Lymphoma | B-cell Malignancy

United States
Carle Foundation Hospital

Unknown

Omegaven® as Parenteral Nutrition

Cholestasis

United States
Carle Physician Group

Terminated

Domperidone for Relief of Gastrointestinal Disorders

Dyspepsia | Nausea | Vomiting | Esophagitis | GERD | Chronic Idiopathic Constipation | Gastroparesis

United States
Cara Therapeutics, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica

Pruritus | Notalgia Paresthetica

United States, Poland, Spain, Canada, Germany
Cara Therapeutics, Inc.

Recruiting

A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KIND-1)

Pruritus | Atopic Dermatitis

United States
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Cala Health, Inc.

Completed

Prospective Study for Symptomatic Relief of ET With Cala Therapy (PROSPECT)

Essential Tremor

United States
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Cholestatic Pruritus

United States
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KARE)

Pruritus | Atopic Dermatitis

United States, Canada
Cara Therapeutics, Inc.

Completed

A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee

Arthritis | Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Cara Therapeutics, Inc.

Completed

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

Healthy

United States
Cara Therapeutics, Inc.

Completed

A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee

Osteoarthritis

United States
Cara Therapeutics, Inc.

Completed

Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritus

Pruritus | Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery

Acute Pain

United States
Cara Therapeutics, Inc.

Completed

A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery

Acute Pain

United States
Fondazione Don Carlo Gnocchi Onlus
Carlo Besta Neurological Institute

Recruiting

SECONDs' Italian Translation and Transcultural Validation (IT-SECONDs)

Disorder of Consciousness

Italy
Cala Health, Inc.

Recruiting

Respiratory-gated Auricular Vagal Afferent Nerve Stimulation (RAVANS) Study in Ulcerative Colitis

Ulcerative Colitis

United States
Cara Medical Ltd

Recruiting

Cara CDRS (Conduction Disturbance Risk Score) 1.0 (CDRS)

Transcatheter Aortic Valve Replacement

Spain, Canada, Italy
Cara Medical Ltd

Recruiting

Cara CDRM (Conduction Disturbance Risk Monitor) 2.0 (Cara CDRM)

Transcatheter Aortic Valve Replacement

United States
Cara Therapeutics, Inc.

Recruiting

CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States, Korea, Republic of, Australia, Bulgaria, Germany, Hungary, Italy, Poland, Romania, Spain, Argentina, Brazil, Mexico
Cala Health, Inc.

Completed

Transcutaneous Afferent Patterned Stimulation (TAPS) for Reduction of Parkinson's Disease (PD) Related Action Tremor

Parkinson Disease

United States
Cara Therapeutics, Inc.

Completed

CR845-100303: Study to Assess the Potential of Physical Withdrawal From Intravenous CR845 (Difelikefalin) in Hemodialysis Patients

Hemodialysis

United States
Cala Health, Inc.

Completed

Symptomatic Relief of Action Tremor With Cala Trio Using Trio+ Bands

Parkinson Disease | Essential Tremor

United States
Cara Therapeutics, Inc.

Completed

CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Czechia, Hungary, Poland
Cara Therapeutics, Inc.

Completed

Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Puerto Rico
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects

Healthy | Hemodialysis

United States
Cala Health, Inc.

Completed

A Pilot Study of the Cala ONE Device for Essential Tremor (EXCITE)

Essential Tremor

United States
Ospedale "Carlo Poma" - Mantova

Completed

Experimental Study About Physiotherapy Treatment vs Self-treatment In Axillary Web Syndrome After Axillary Dissection

Breast Neoplasms

Italy
University of Campania "Luigi Vanvitelli"
IRCCS Multimedica; Cardarelli Hospital

Completed

Pollutants in the Atherosclerotic Plaque and Cardiovascular Events (APAChE)

Atherosclerosis

Italy
Ospedale San Carlo Borromeo

Active, not recruiting

Panitumumab Skin Toxicity Prevention Trial (PaSTo)

Colorectal Cancer Metastatic | Skin Toxicity

Italy
Cara Medical Ltd

Recruiting

Intra-procedural ECG Changes During TAVR

Transcatheter Aortic Valve Replacement | Conduction Disturbance

United States
Cala Health, Inc.

Not yet recruiting

Peripheral Nerve Stimulation Therapy for Atrial Fibrillation

Atrial Fibrillation

United States
Cala Health, Inc.

Completed

Cala ONE Device for Essential Tremor

Essential Tremor

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT)

Pruritus | Notalgia Paresthetica

United States, Canada
Cara Therapeutics, Inc.

Approved for marketing

Intermediate-Size Patient Population Expanded Access Program for Intravenous Difelikefalin

Uremic Pruritus
Cara Therapeutics, Inc.

Completed

CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-2)

Uremic Pruritus

United States, Canada, Czechia, Australia, Germany, Hungary, Korea, Republic of, New Zealand, Poland, Taiwan, United Kingdom
Cara Therapeutics, Inc.

Completed

Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States

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