Clinical Trials Sponsored by Cearna, Inc.

Total 35508 results

Cearna, Inc.

Unknown

A Study of Topical Arnica & Ledum on Bruise Reduction in HNV

Bruise, Contusion
Cearna, Inc.

Unknown

Development of Validated Bruise Scale in HNV

Bruise, Contusion

United States
Carna Biosciences, Inc.

Recruiting

AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

Follicular Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Non-Hodgkin Lymphoma | Small Lymphocytic Lymphoma | B-cell Malignancy

United States
Cara Therapeutics, Inc.

Recruiting

CR845-310302: A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States, Korea, Republic of, Australia, Bulgaria, Germany, Hungary, Italy, Poland, Romania, Spain, Argentina, Brazil, Mexico
Cara Therapeutics, Inc.

Completed

CR845-100303: Study to Assess the Potential of Physical Withdrawal From Intravenous CR845 (Difelikefalin) in Hemodialysis Patients

Hemodialysis

United States
Cara Therapeutics, Inc.

Completed

CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Czechia, Hungary, Poland
Cara Therapeutics, Inc.

Completed

Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States, Puerto Rico
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects

Healthy | Hemodialysis

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT)

Pruritus | Notalgia Paresthetica

United States, Canada
Cara Therapeutics, Inc.

Approved for marketing

Intermediate-Size Patient Population Expanded Access Program for Intravenous Difelikefalin

Uremic Pruritus
Cara Therapeutics, Inc.

Completed

CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-2)

Uremic Pruritus

United States, Canada, Czechia, Australia, Germany, Hungary, Korea, Republic of, New Zealand, Poland, Taiwan, United Kingdom
Cara Therapeutics, Inc.

Completed

Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery

Post Abdominal Surgery Pain

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate Analgesic Effect of IV Administration of Kappa Agonist CR845 For Hysterectomy Surgery

Postoperative Pain

United States
Cara Therapeutics, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica

Pruritus | Notalgia Paresthetica

United States, Poland, Spain, Canada, Germany
Cara Therapeutics, Inc.

Recruiting

A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KIND-1)

Pruritus | Atopic Dermatitis

United States
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus

Chronic Kidney Diseases | Pruritus

United States
Cara Therapeutics, Inc.

Terminated

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Cholestatic Pruritus

United States
Cara Therapeutics, Inc.

Completed

A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)

Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (KARE)

Pruritus | Atopic Dermatitis

United States, Canada
Cara Therapeutics, Inc.

Completed

A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee

Arthritis | Joint Diseases | Musculoskeletal Diseases | Rheumatic Diseases | Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Cara Therapeutics, Inc.

Completed

Study to Investigate the Effects of Single Intravenous Doses of Difelikefalin (CR845) on the QTc Interval in Healthy Subjects

Healthy

United States
Cara Therapeutics, Inc.

Completed

A Study of the Safety and Effectiveness of Orally Administered CR845 in Patients With Osteoarthritis of the Hip or Knee

Osteoarthritis

United States
Cara Therapeutics, Inc.

Completed

Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritus

Pruritus | Uremic Pruritus

United States
Cara Therapeutics, Inc.

Completed

Study to Evaluate Analgesic Effect of Intravenous Administration of Kappa Agonist CR845 After Hysterectomy Surgery

Acute Pain

United States
Cara Therapeutics, Inc.

Completed

A Phase 2 Study to Evaluate Analgesic Effect of IV CR845 For Pain Following Bunionectomy Surgery

Acute Pain

United States
Envision Healthcare Scientific Intelligence, Inc.
Cianna Medical, Inc.

Completed

Long Term Use of SAVI SCOUT: Pilot Study

Breast Diseases

United States
Universidade Federal do Ceará

Not yet recruiting

Addition Effect of the Ankle Manual Therapy to Muscle Strengthening Exercise in Women With Patellofemoral Pain (PhD_Bruno)

Patellofemoral Pain Syndrome

Brazil
Universidade Federal do Ceará

Completed

Effect of Two Strengthening Protocols for Lower Limbs in Patients With Patellofemoral Pain

Patellofemoral Pain Syndrome

Brazil
Universidade Federal do Ceará

Completed

Effects of Diaphragm-releasing Techniques on the Lumbar Spine and Diaphragmatic Function in Healthy Women

Healthy Individuals
Universidade Federal do Ceará

Completed

Effect of Strengthening the Hip Abductor in Patients With Knee Osteoarthritis: Randomized Controlled Trial

Osteoarthritis, Knee

Brazil
Universidade Federal do Ceará

Completed

Respiratory Muscle Training in Hemodialysis Patients

Renal Failure

Brazil
Universidade Federal do Ceará

Completed

Immediate Effects of Ankle Mobilization on Dorsiflexion Range of Motion in Women With Patellofemoral Pain. (Mestrado)

Patellofemoral Pain Syndrome

Brazil
Universidade Federal do Ceará

Completed

Effects of Auriculotherapy on Pain and Functional Capacity of Individuals With Chikungunya Fever

Chikungunya Fever

Brazil
Universidade Federal do Ceará

Unknown

Comparison Between Two Mobilization Techniques of Ankle on Balance in Patients With Chronic Ankle Instability

Ankle Sprains

Brazil
Universidade Federal do Ceará

Unknown

Immediate Effects of Two Ankle Mobilization Techniques in the Amplitude of Dorsiflexion and Dynamic Valgus Knee

Knee Injuries and Disorders | Ankle Joint Contracture

Brazil
Universidade Federal do Ceará

Unknown

Effectiveness of a Jaw Exercise Program in Temporomandibular Disorders Patients

Musculoskeletal Diseases | Temporomandibular Joint Disorders

Brazil
Universidade Federal do Ceará

Not yet recruiting

Effect of Low Intensity Training Combined With Partial Restriction of Blood Flow in Individuals With Knee Osteoarthritis

Osteoarthritis, Knee
Universidade Federal do Ceará

Completed

NIV Reduces CBF in COPD Patients Without Cognitive Function

Cerebral Blood Flow | Cognitive Impairment | COPD | Non-invasive Ventilation
Universidade Federal do Ceará

Completed

Immediate Effects of Posterior Mobilization Versus Caudal Mobilization in Patients With Temporomandibular Disorders (TMD)

Temporomandibular Disorders

Brazil
Universidade Federal do Ceará

Completed

Effect of Physical Exercise on Endothelial Function in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus

Brazil
Universidade Federal do Ceará

Unknown

Efficacy of Chlorexidine as Intracanal Medicament in Primary Teeth

Dental Pulp Necrosis

Brazil
Universidade Federal do Ceará

Completed

The Use of Antimicrobial Agents in the Inhibition of Mutans Streptococci in Children With Dental Caries

Dental Caries

Brazil
Cianna Medical, Inc.
University of South Florida

Unknown

SAVI SCOUT Clinical Evaluation Study

Breast Neoplasm
Starna Therapeutics

Not yet recruiting

A Study to Describe the Safety and Immunogenicity of a Respiratory Syncytial Virus Vaccine STR-V003 in Healthy Adults (STR-V003)

Respiratory Syncytial Virus Infections
Bausch Health Americas, Inc.
Galderma R&D; Oceana Therapeutics, Inc.

Completed

A Randomized, Blinded, Multicenter Study to Evaluate NASHA/Dx for the Treatment of Fecal Incontinence

Fecal Incontinence

United States, Germany, Sweden, United Kingdom
Instituto do Cancer do Ceara

Completed

Phase 2 Study of Adjuvant Radiotherapy in Breast Cancer Using a Once a Week Hypofractionated Regimen

Breast Neoplasms

Brazil
Cipherome, Inc.
Santa Clara Valley Medical Center

Completed

Association Between Genetic Variant Scores and Warfarin Effect (AWARE1)

Atrial Fibrillation | Deep Vein Thrombosis | Pulmonary Embolism | Intracardiac Thrombus | Venous Thromboembolic Disease

United States
Cipherome, Inc.
Santa Clara Valley Medical Center

Terminated

DOAC ADRs Retrospective Study

Drug-Related Side Effects and Adverse Reactions

United States

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