Clinical Trials Sponsored by Centre for Trials Research, Cardiff University

Total 2231 results

University of Manchester
Cancer Research UK; Centre for Trials Research, Cardiff University

Recruiting

Validation of Tie2 as the First Tumour Vascular Response Biomarker for VEGF Inhibitors: VALTIVE1 (VALTIVE1)

Ovary Cancer

United Kingdom
Cardiff University
National Institute for Health Research, United Kingdom; Wales Cancer Trials...

Terminated

Anticoagulation Length in Cancer Associated Thrombosis (ALICAT)

Cancer | Thrombosis | Deep Vein Thrombosis | Venous Thromboembolism | Pulmonary Embolus

United Kingdom
National Research Center for Cardiac Surgery, Kazakhstan
Nazarbayev University Medical Center

Recruiting

Clinical, Functional, Immunological and Genetic Factors on the Severity of the Course of Coronavirus Infection

Covid19 | Corona Virus Infection

Kazakhstan
Cardiff University
National Institute for Social Care and Health Research

Completed

Prostaglandin F2-alpha Eye Drops in Thyroid Eye Disease (Bima Study) (BIMA)

Graves' Ophthalmopathy

United Kingdom
Copenhagen Trial Unit, Center for Clinical Intervention...

Not yet recruiting

Safeguarding the Brain of Our Smallest Children-IIIv (SafeBoosC-IIIv) (SafeBoosC-IIIv)

Infant, Newborn, Diseases | Hypoxia
Cardiff University
Medical Research Council; National Institute for Social Care and Health Research

Completed

Neurofeedback as a Treatment Tool for Depression (NFD)

Unipolar Depression

United Kingdom
Cardiff University
Juvenile Diabetes Research Foundation; Diabetes Vaccine Development Centre

Completed

Safety Study to Assess Whether Proinsulin Peptide Injections Can Slow or Stop the Body Damaging Its Own Insulin-making Cells in the Pancreas in Patients Newly Diagnosed With Type 1 Diabetes (MonoPepT1De)

Type 1 Diabetes

United Kingdom
Anne Katrine Pagsberg
Copenhagen Trial Unit, Center for Clinical Intervention Research; Danish Research...

Active, not recruiting

Treatment Effects of Family Based Cognitive Therapy in Children and Adolescents With Obsessive Compulsive Disorder (TECTO)

Obsessive-Compulsive Disorder in Children | Obsessive-Compulsive Disorder in Adolescence

Denmark
Scandinavian Critical Care Trials Group
Rigshospitalet, Denmark; University of Copenhagen; Copenhagen Trial Unit, Center...

Completed

Transfusion-requirements in Septic Shock Trial (TRISS)

Septic Shock

Sweden, Norway, Finland, Denmark
JHSPH Center for Clinical Trials
University of Pittsburgh

Completed

Losartan Effects on Emphysema Progression (LEEP)

Emphysema

United States
University Medical Center Groningen
Copenhagen Trial Unit, Center for Clinical Intervention Research

Completed

Simple Intensive Care Studies I (SICS-I) (SICS-I)

Shock | Critical Illness | Acute Disease

Netherlands
Cardiff University
Experimental Cancer Medicine Centres; Leukaemia & Lymphoma Research Group

Completed

A Trial to Establish the Feasibility of Combining Either the Tyrosine Kinase Inhibitor AC220,CXCR4 Inhibitor Plerixafor or HSP90 Inhibitor Ganetespib With Chemotherapy in Older Patients With Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome. (AML18 Pilot)

High Risk Myelodysplastic Syndrome | Acute Myeloid Leukaemia

United Kingdom
Zealand University Hospital
Copenhagen Trial Unit, Center for Clinical Intervention Research; Scandinavian... and other collaborators

Active, not recruiting

Agents Intervening Against Delirium in Intensive Care Unit (AID-ICU)

Delirium

Denmark, Finland, Italy, United Kingdom
University of Cologne
Stanley Medical Research Institute; Coordinating Centre for Clinical Trials...

Completed

A Clinical Trial on the Antipsychotic Properties of Cannabidiol

Psychotic Disorders | Schizophrenia

Germany
University of Birmingham
Cardiff University; King Abdullah International Medical Research Center

Completed

Apnoeic Oxygenation by Nasal Cannula During Airway Management in Children Undergoing General Anaesthesia.

Apnoeic Oxygenation
Naestved Hospital
Copenhagen Trial Unit, Center for Clinical Intervention Research

Completed

Effect of Dexamethasone as Analgesic Treatment After Total Knee Arthroplasty

Postoperative Pain

Denmark
Copenhagen Trial Unit, Center for Clinical Intervention...
Bispebjerg Hospital

Completed

Eccentric Exercise in Treatment of Achilles Tendinopathy

Achillodynia

Denmark
Copenhagen Trial Unit, Center for Clinical Intervention...
Bispebjerg Hospital

Completed

KATHY:Cognitive-behavioural Therapy for Hypochondriasis

Hypochondriasis
Rigshospitalet, Denmark
Copenhagen Trial Unit, Center for Clinical Intervention Research

Unknown

The FEEDBACK Trial, a Randomized Controlled Trial (Feedback)

Laparoscopic Proficiency

Denmark
Rigshospitalet, Denmark
Copenhagen Trial Unit, Center for Clinical Intervention Research

Recruiting

The Anesthetic Ketamine as Treatment for Patients With Severe Acute Brain Injury (KETA-BID)

Traumatic Brain Injury | Subarachnoid Hemorrhage, Aneurysmal | Intracerebral Hemorrhage

Denmark
Rigshospitalet, Denmark
Copenhagen Trial Unit, Center for Clinical Intervention Research

Completed

CopenHeartRFA - Integrated Rehabilitation of Patients Treated for Atrial Fibrillation With Radio Frequency Ablation

Atrial Fibrillation

Denmark
Rigshospitalet, Denmark
Copenhagen Trial Unit, Center for Clinical Intervention Research

Completed

'In Situ Simulation' Versus 'Off Site Simulation' in Obstetric Emergencies

Simulation | Education | Obstetrics | 'In Situ Simulation'

Denmark
Scandinavian Critical Care Trials Group
Aarhus University Hospital; Rigshospitalet, Denmark; University of Copenhagen; Copenhagen...

Completed

Hydrocortisone for COVID-19 and Severe Hypoxia (COVID STEROID)

Covid-19 | Hypoxia

Denmark
Institute for Clinical Evaluative Sciences
Peter Munk Cardiac Centre; Vector Institute for Artificial Intelligence; Ted...

Recruiting

Predicting Readmissions Using Omics, Biostatistical Evaluate and Artificial Intelligence (PROBE AI)

Heart Failure

Canada
Scandinavian Critical Care Trials Group
Aarhus University Hospital; Rigshospitalet, Denmark; Aalborg University Hospital and other collaborators

Completed

Higher vs. Lower Doses of Dexamethasone for COVID-19 and Severe Hypoxia (COVIDSTEROID2)

Hypoxia | Covid19

Sweden, India, Denmark, Switzerland
Dr. Morten Hylander Møller
Rigshospitalet, Denmark; Copenhagen Trial Unit, Center for Clinical Intervention...

Completed

Stress Ulcer Prophylaxis in the Intensive Care Unit (SUP-ICU)

Gastrointestinal Bleeding | Stress Ulcers

Denmark, Netherlands, Switzerland, Norway, Finland, United Kingdom
University of Heidelberg Medical Center
German Cancer Research Center; University Hospital Heidelberg; Array BioPharma; Coordinating Centre for Clinical Trials Heidelberg

Active, not recruiting

BRAF/MEK Inhibition in Relapsed/Refractory Multiple Myeloma (BIRMA) (GMMG-BIRMA)

Relapsed or Refractory Multiple Myeloma | Patients With BRAFV600 E or BRAFV600K Mutation

Germany
The George Institute
Victor Chang Cardiac Research Institute; St Vincent's Centre for Applied Medical...

Recruiting

Polydiuretic Therapy for HFpEF, a Randomised Controlled Trial

Heart Failure With Preserved Ejection Fraction

Australia
M.D. Anderson Cancer Center
Patient-Centered Outcomes Research Institute; Alliance for Clinical Trials...

Completed

Patient-Centered Risk Adjusted Surveillance After Curative Resection of Colorectal Cancer

Colorectal Cancer

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Canadian Cancer Trials Group; European Organisation...

Recruiting

Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemotherapy in Patients With Anaplastic Glioma or Low Grade Glioma

Brain and Central Nervous System Tumors

United States, Canada, France, Netherlands, Austria, Belgium
Morten H. Bestle
University of Copenhagen; Copenhagen Trial Unit, Center for Clinical Intervention... and other collaborators

Recruiting

Controlled Fluid Removal in Critical Ill Patients With Fluid Overload in the Intensive Care Unit. (GODIF)

Fluid Overload

Denmark, Finland, Norway, Iceland, Netherlands, Switzerland
Cardiff and Vale University Health Board
Welsh Value in Health Centre (WViHC); Centre for Healthcare Evaluation, Device...

Not yet recruiting

PREMs In Vascular SurgERy Enhancement Study (PREMIERE)

Vascular Diseases | Surgery | Patient Engagement | Patient Satisfaction | Patient Empowerment

United Kingdom
University of Virginia
Patient-Centered Outcomes Research Institute; Alliance for Clinical Trials...

Completed

Post-Treatment Surveillance in Lung Cancer

Lung Cancer
University of Virginia
Patient-Centered Outcomes Research Institute; Alliance for Clinical Trials...

Completed

A Study of Patient-reported Outcomes in Patients With Lung or Esophageal Cancer

Esophageal Cancer | Lung Cancer

United States
Aalborg University Hospital
Rigshospitalet, Denmark; Copenhagen Trial Unit, Center for Clinical Intervention...

Active, not recruiting

Handling Oxygenation Targets in COVID-19 (HOT-COVID)

Hypoxemic Respiratory Failure | Oxygen Toxicity

Norway, Switzerland, Denmark
Niklas Nielsen
Lund University; The George Institute for Global Health, Australia; Copenhagen... and other collaborators

Completed

Target Temperature Management After Cardiac Arrest (TTM)

Out-of-hospital Cardiac Arrest

Sweden, Netherlands, Norway, United Kingdom, Italy, Australia, Switzerland, Luxembourg, Czech Republic, Denmark
Rigshospitalet, Denmark
University of Copenhagen; Copenhagen Trial Unit, Center for Clinical Intervention...

Completed

Is the Volume of the Caudate Nuclei Associated With Area of Secondary Hyperalgesia?

Pain | Healthy Volunteers | Magnetic Resonance Imaging | Secondary Hyperalgesia

Denmark
Rigshospitalet, Denmark
University of Copenhagen; Copenhagen Trial Unit, Center for Clinical Intervention...

Completed

Association Between Heat Pain Detection Threshold and Area of Secondary Hyperalgesia

Healthy

Denmark
Rigshospitalet, Denmark
University of Copenhagen; Copenhagen Trial Unit, Center for Clinical Intervention...

Completed

Characterization of Secondary Hyperalgesia in Healthy Volunteers

Experimental Pain in Healthy Males

Denmark
United Neuroscience Ltd.
Worldwide Clinical Trials; Centre for Human Drug Research, Netherlands; Vaxxinity...

Completed

Study of UB-312 in Healthy Participants and Parkinson's Disease Patients

Parkinson's Disease | Parkinsonism

Netherlands
Manchester University NHS Foundation Trust
University College, London; University Hospital Southampton NHS Foundation... and other collaborators

Recruiting

Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate (SLUMBRS2)

Obstructive Sleep Apnea | Cleft Palate

United Kingdom
Aalborg University Hospital
Rigshospitalet, Denmark; Copenhagen Trial Unit, Center for Clinical Intervention...

Completed

Handling Oxygenation Targets in the Intensive Care Unit (HOT-ICU)

Hypoxemic Respiratory Failure | Oxygen Toxicity

United Kingdom, Denmark, Finland, Iceland, Netherlands, Norway, Switzerland
Karolinska Institutet
Aarhus University Hospital; Rigshospitalet, Denmark; Linkoeping University; Aalborg... and other collaborators

Completed

The Effect of Dexamethasone 12 mg vs 6 mg on Thromboembolic Events in Patients With Critical COVID-19

COVID-19 | Bleeding | Thrombosis Embolism

Sweden
Charite University, Berlin, Germany
German Federal Ministry of Education and Research; SepNet - Critical Care Trials... and other collaborators

Completed

Hydrocortisone for Prevention of Septic Shock (HYPRESS)

Severe Sepsis

Germany
Centre for Human Drug Research, Netherlands
Leiden University Medical Center; Leiden Academic Center for Drug Research,...

Completed

Adalimumab Microneedles in Healthy Volunteers

Pain | Injection Site

Netherlands
University Hospital Birmingham NHS Foundation Trust
University of Birmingham; National Institute for Health Research, United Kingdom and other collaborators

Unknown

Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy? (D-CODE)

Vitamin D Deficiency | Crohn Disease

United Kingdom
Rigshospitalet, Denmark
University Hospital, Gentofte, Copenhagen; Copenhagen Trial Unit, Center for...

Completed

CopenHeart IE - Integrated Rehabilitation of Patients Treated for Infective Endocarditis

Infective Endocarditis

Denmark
University of Oxford
National Institute for Health Research, United Kingdom; Oxford Clinical Trials...

Completed

Can we Use Estrogen-containing Therapy to Improve Pain in Women After Menopause With Hand Osteoarthritis? (HOPE-e)

Hand Osteoarthritis

United Kingdom
Philipps University Marburg Medical Center
Johannes Gutenberg University Mainz; Philipps University Marburg Coordination...

Terminated

Alternative Dosing Regimens in the Pharmacotherapy of Insomnia (ALPHASOM)

Insomnia

Germany
University College, London
Cancer Research UK; Cancer Research UK & UCL Cancer Trials Centre

Active, not recruiting

Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin Lymphoma

Lymphoma

United Kingdom

Clinical Trials Sponsored by Centre for Trials Research, Cardiff University

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CROs in Indonesia

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