Clinical Trials Sponsored by Centre for Probe Development and Commercialization

Total 622 results

Centre for Probe Development and Commercialization

Completed

A Safety and Biodistribution Study of [I-124]-CPD-1028 Injection in Solid Tumours

Cancer

Canada
GE Healthcare
Centre for Probe Development and Commercialization

Completed

Assess Safety, Bio-distribution, Radiation Dosimetry and Optimize the Imaging Protocol of GEH120714 (18F) Injection in Healthy Volunteers and Participants With Relapsing and Remitting Multiple Sclerosis (rrMS).

Relapsing-remitting Multiple Sclerosis (rrMS)

Canada
Centre for Probe Development and Commercialization
McDougall Scientific Ltd.

Completed

Safety and Efficacy of [18F]PSMA-1007 Injection in Suspected Persistent or Recurrent Prostate Cancer.

Recurrent Prostate Cancer | Prostate Cancer Recurrent

Canada
Centre for Probe Development and Commercialization
St. Joseph's Healthcare Hamilton; McMaster University

Completed

A Single Centre Open Label Comparison of [I-123]-Ortho-Iodohippuric Acid (OIH) With [Tc-99m]-Mercaptoacetyltriglycine (MAG3) for Assessment of Renal Tubular Function

Renal Function Impairment

Canada
Lawson Health Research Institute
Cancer Care Ontario; Centre for Probe Development and Commercialization

Recruiting

PSMA-PET Registry for Recurrent Prostate Cancer (PREP)

Recurrent Prostate Cancer

Canada
Glenn Bauman
United States Department of Defense; Western University, Canada; Centre for Probe...

Recruiting

Multi-modality Imaging (PCa) Using Sodium MRI and PSMA PET in Men Pre-prostatectomy (IGPC-5)

Prostate Cancer | Prostate Adenocarcinoma | Prostate Neoplasm

Canada
British Columbia Cancer Agency
Canadian Institutes of Health Research (CIHR); Lawson Health Research Institute and other collaborators

Completed

A Blinded Study Evaluating the Accuracy and Safety of Cyclotron-produced 99mTc in Adult Patients

Hyperthyroidism

Canada
Otsuka Pharmaceutical Development & Commercialization...
Center for International Blood and Marrow Transplant Research

Completed

PK-directed Dose Adjustment of IV Busulfan Conditioning Regimen for Autologous Stem Cell Transplant in Lymphoma Patients

Lymphoma

United States, Canada
Durham VA Medical Center
Otsuka Pharmaceutical Development and Commercialization, Inc.

Unknown

DIMES - DIgital MEdicine Study for Adults With Schizophrenia, Bipolar I Disorder, or Major Depression Currently Using Aripiprazole (DIMES)

Schizophrenia | Major Depressive Disorder | Schizo Affective Disorder | Bi-Polar Disorder

United States
Northeast Center for Rehabilitation and Brain Injury
Probed Medical USA

Unknown

Effectiveness of the Freedom Bed as Compared to Alternating Pressure Mattress in Treatment of Pressure Injuries in Persons With Limited Mobility Due to Traumatic Brain Injury and /or Spinal Cord Injury

Pressure Injury

United States
Northeast Center for Rehabilitation and Brain Injury
Probed Medical USA

Unknown

Effectiveness of Freedom Bed Compared to Manual Turning in Prevention of Pressure Injuries in Persons With Limited Mobility Due to Traumatic Brain Injury and/or Spinal Cord Injury.

Pressure Ulcer
Center for International Health and Development
Centers for Disease Control and Prevention

Completed

Intermittent Preventive Treatment of Malaria in HIV-Seropositive Pregnant Women in Zambia

HIV Infections | Prematurity | Stillbirth | Neonatal Deaths | Placental Malaria Infection

Zambia
Silesian Centre for Heart Diseases
National Center for Research and Development, Poland

Completed

Remote Supervision to Decrease Hospitalization Rate (RESULT)

Heart Failure

Poland
Centers for Disease Control and Prevention
Ifakara Health Research and Development Centre

Completed

Adherence to Lumefantrine-Artemether

Malaria, Uncomplicated

Tanzania
Centers for Disease Control and Prevention
Ifakara Health Research and Development Centre

Completed

Efficacy of Combination Therapy for Prevention of Effects of Malaria During Pregnancy

Malaria

Tanzania
Ardigen
National Center for Research and Development, Poland

Recruiting

Creating an Innovative AI-based Technology TCRact for Designing and Optimizing T-cell Receptors (TCR) for Use in Cancer Immunotherapies

Cancer | Colon Cancer

Poland
Neopenda, PBC
Center for Public Health and Development

Completed

Feasibility Study Evaluating the Efficacy of a Wireless Vital Signs Monitor for Critically Ill Newborns in Kenya

Newborn Morbidity | Newborn Complication

Kenya
Ardigen
National Center for Research and Development, Poland

Unknown

BioForte Technology for in Silico Identification of Candidates for a New Microbiome-based Therapeutics and Diagnostics

Melanoma | Non Small Cell Lung Cancer | Metagenome | Immunotherapy | Microbiome

Poland
Center for International Blood and Marrow Transplant...
Otsuka Pharmaceutical Development & Commercialization, Inc.; Pediatric Blood... and other collaborators

Completed

MRD Testing Before and After Hematopoietic Cell Transplantation for Pediatric Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States, Canada
DBL -Institute for Health Research and Development
Centre Muraz

Completed

Schistosomiasis in Women of Reproductive Age in Burkina Faso: Implications for Control

Pregnancy | Anaemia | Schistosomiasis

Burkina Faso
Boston University
United States Agency for International Development (USAID); Center for International...

Completed

Zambia Integrated Management of Malaria and Pneumonia Study (ZIMMAPS)

Pneumonia | Malaria

Zambia
Centers for Disease Control and Prevention
Education Development Center, Inc.; Ministry of Education and Skills Development...

Completed

An Assessment of an HIV Prevention Intervention (Project AIM) Among Junior Secondary School Students in Eastern Botswana (AIM)

HIV

Botswana
Celon Pharma SA
National Center for Research and Development, Poland

Recruiting

Efficacy, Safety and Pharmacokinetic Study of CPL500036 in Patients With Levodopa Induced Dyskinesia

Parkinson Disease | Dyskinesia, Medication-Induced

Poland, Ukraine
Celon Pharma SA
National Center for Research and Development, Poland

Recruiting

Efficacy, Safety and Pharmacokinetics Study of CPL500036 (PDE10A Inhibitor) in Patients With Schizophrenia

Schizophrenia

Hungary, Poland, Ukraine
Jagiellonian University
National Center for Research and Development, Poland; KCRI

Completed

Clinical Trial to Evaluate Safety and Efficacy of MesoCellA-Ortho Tissue-Engineered Advanced Therapy Product in Patients With Osteoarthrosis and Civilisation Diseases (BioMiStem-CT)

Osteoarthritis of Knee

Poland
OASIS Diagnostics S.A.
National Center for Research and Development, Poland

Completed

Detection of Obstetric Anal Sphincter Injuries With ONIRY Device

Obstetric Complication | Delivery Complication | Obstetric Anal Sphincter Injury

Spain, Czechia, Poland, Slovakia
Celon Pharma SA
National Center for Research and Development, Poland

Recruiting

Efficacy and Safety Study Comparing CPL409116 to Placebo in Participants With Active Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, Ukraine
Celon Pharma SA
National Center for Research and Development, Poland

Recruiting

Efficacy, Safety and Pharmacokinetics Study of CPL207280 After 2-weeks Administration in Subjects With Type 2 Diabetes

Type 2 Diabetes

Poland
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Depression

Major Depressive Disorder

Poland
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Safety and Pharmacokinetics Study of CPL500036 Compound in Healthy Volunteers

Healthy Volunteers

Poland
VA Office of Research and Development
National Center for PTSD

Recruiting

rTMS-augmented Written Exposure Therapy for PTSD

Post Traumatic Stress Disorder

United States
Celon Pharma SA
National Center for Research and Development, Poland

Recruiting

Safety, Tolerability and Pharmacokinetics of Oral CPL304110, in Adult Subjects With Advanced Solid Malignancies

Sarcoma | Gastric Cancer | Cholangiocarcinoma | Bladder Cancer | Endometrial Cancer | Squamous Non-small Cell Lung Cancer | Other Solid Tumours

Poland
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Safety and Pharmacokinetics of JAK/ROCK Inhibitor in Healthy Volunteers

Healthy

Poland
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Safety and Pharmacokinetics Study of CPL207280 Compound in Healthy Volunteers.

Healthy Volunteers

Poland
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depression

Bipolar Depression

Poland
Kardio-Med Silesia
National Center for Research and Development, Poland

Completed

Non-invasive Monitoring for Early Detection of Atrial Fibrillation

Atrial Fibrillation

Poland
Celon Pharma SA
National Center for Research and Development, Poland

Completed

Safety and Pharmacokinetic Study of Inhaled Esketamine in Healthy Volunteers

Healthy Volunteers

Poland
National Center for Telehealth and Technology
VA Office of Research and Development

Completed

A Randomized Controlled Trial of In-Home Tele-Behavioral Health Care Utilizing Behavioral Activation for Depression

Depression

United States
Zambia Center for Applied Health Research and Development
Department for International Development, United Kingdom; PATH; Grand Challenges...

Completed

Improving Early Childhood Development in Zambia (IECDZ)

Child Development | Stunting

Zambia
Centers for Disease Control and Prevention
United States Agency for International Development (USAID)

Completed

Efficacy of Sulphadoxine-pyrimethamine and Artemisinin-containing Combination Therapy for Malaria

Malaria (Uncomplicated)

Tanzania
Centers for Disease Control and Prevention
Bayer; Global Alliance for TB Drug Development

Completed

TBTC Study 28: Moxifloxacin Versus Isoniazid for TB Treatment

Tuberculosis

Uganda, United States, South Africa, Canada, Brazil, Spain
Centers for Disease Control and Prevention
VA Office of Research and Development

Completed

Three Months of Weekly Rifapentine and Isoniazid for M. Tuberculosis Infection (PREVENT TB)

Tuberculosis

United States, Canada, Spain, Brazil
National Cerebral and Cardiovascular Center, Japan
Japan Agency for Medical Research and Development

Completed

The Bleeding With Antithrombotic Therapy Study 2 (BAT2)

Cerebrovascular and Cardiovascular Diseases

Japan
Chumakov Federal Scientific Center for Research...

Completed

Observational Program, Study the Preventive Efficacy of the BiVac Polio Vaccine Against the Incidence of Acute Respiratory Infections, Including COVID-19

Coronavirus Infections | Polio | Vaccine

Russian Federation
Chumakov Federal Scientific Center for Research...

Active, not recruiting

An Open Comparative Study of the Effectiveness and Incomparable Study of the Immunogenicity and Safety of the Vaccine (CoviVac) for Adults Aged 60 Years and Older

COVID-19 | Corona Virus Infection | Vaccine

Russian Federation
Chumakov Federal Scientific Center for Research...

Active, not recruiting

Double-blind, Placebo-controlled, Randomized Study of the Tolerability, Safety and Immunogenicity of an Inactivated Whole Virion Concentrated Purified Vaccine (CoviVac) Against Covid-19 of Children at the Age of 12-17 Years Inclusive"

Vaccine

Russian Federation
Chumakov Federal Scientific Center for Research...

Recruiting

An Open Comprative Study of the Prophylactic Efficacy and a Non-comparative Study of the Immunogenicity and Safety of the Inactivated Whole-virion Concentrated Purified Coronavirus Vaccine (CoviVac)

Coronavirus Infections | Vaccine

Russian Federation
Chumakov Federal Scientific Center for Research...

Completed

This is a Double-blind, Placebo-controlled, Randomized Study of the Tolerability, Safety and Immunogenicity of an Inactivated Whole Virion Concentrated Purified Vaccine (CoviVac) Against Covid-19

Coronavirus Infections | Vaccine

Russian Federation
MENA Center for Research & Development and Internship
Merck Sharp & Dohme LLC

Recruiting

The Epidemiology , Health and Economic Burden of RSV Amongst Hospitalized Children Under 5 Years of Age in Jordan (RSV-JO)

Respiratory Syncytial Virus Infections

Jordan
Medical University of Gdansk
National Center for Research and Development, Poland

Completed

The Impact of Pituitary-thyroid and Pituitary-adrenal Axes Function on COVID-19 Clinical Course. (ENDO-COVID19)

COVID-19 | Hypothyroidism | Hyperthyroidism | Adrenal Insufficiency | Low Triiodothyronine Syndrome | Subacute Thyroiditis

Poland

Clinical Trials Sponsored by Centre for Probe Development and Commercialization

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