Clinical Trials Sponsored by Children's Cancer and Leukaemia Group

Total 1596 results

University of Manchester
Children's Cancer and Leukaemia Group

Recruiting

Granulocyte Transfusions After Umbilical Cord Blood Transplant

Pediatric Cancer

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors

Brain and Central Nervous System Tumors | Neuroblastoma

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Thiotepa and Radiation Therapy in Treating Young Patients With Newly Diagnosed Malignant Brain Tumors

Brain and Central Nervous System Tumors
Children's Cancer and Leukaemia Group

Unknown

Chemotherapy With or Without Radiation Therapy or Observation in Treating Young Patients With Advanced Retinoblastoma Who Have Undergone Surgery to Remove the Eye

Retinoblastoma

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy Followed By Surgery With or Without Radiation Therapy in Treating Young Patients With Stage II or Stage III Neuroblastoma

Neuroblastoma

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Irinotecan in Treating Young Patients With Refractory or Recurrent Hepatoblastoma

Liver Cancer

United Kingdom, Netherlands, Ireland
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy Followed By Donor Stem Cell Transplant in Treating Patients With Hemophagocytic Lymphohistiocytosis

Nonneoplastic Condition

United Kingdom
Children's Cancer and Leukaemia Group

Completed

Temozolomide in Treating Young Patients With High-Risk Relapsed or Refractory Neuroblastoma

Neuroblastoma

United Kingdom, Ireland, France
Children's Cancer and Leukaemia Group

Unknown

Etoposide, Carboplatin, and Bleomycin in Treating Young Patients Undergoing Surgery For Malignant Germ Cell Tumors

Ovarian Cancer | Brain and Central Nervous System Tumors | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Observation and/or Combination Chemotherapy After Surgery or Biopsy in Treating Young Patients With Extracranial Germ Cell Tumors

Ovarian Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Tumor Tissue, Blood Samples, and Family History in Predicting Tumor Development and Response to Treatment in Young Patients With Low-Grade Glioma

Brain and Central Nervous System Tumors

United Kingdom
Children's Cancer and Leukaemia Group

Completed

Combination Chemotherapy in Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia

Leukemia

United Kingdom, Australia
Children's Cancer and Leukaemia Group

Unknown

Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma

Brain and Central Nervous System Tumors

Ireland, United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Pharmacokinetics of Dactinomycin in Young Patients With Cancer

Unspecified Childhood Solid Tumor, Protocol Specific

Ireland, United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Etoposide in Treating Young Patients With Relapsed Ependymoma

Brain and Central Nervous System Tumors

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy and/or Radiation Therapy in Treating Young Patients With Hodgkin's Lymphoma

Lymphoma
Children's Cancer and Leukaemia Group

Completed

Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy and Surgery With or Without Radiation Therapy in Treating Patients With Stage 2 or Stage 3 Neuroblastoma

Neuroblastoma
Children's Cancer and Leukaemia Group

Withdrawn

High-Dose Iodine I 131 Metaiodobenzylguanidine, Topotecan, and Peripheral Stem Cell Transplant in Treating Young Patients With Relapsed Stage 4 Neuroblastoma or Primary Resistant High-Risk Neuroblastoma

Neuroblastoma
Children's Cancer and Leukaemia Group

Completed

High-Dose Methotrexate in Treating Young Patients With Solid Tumors

Sarcoma | Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Completed

Irinotecan in Treating Patients With Newly Diagnosed Ewing's Sarcoma

Sarcoma

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Quality of Life in Patients Who Have Undergone Previous Treatment for Primitive Neuroectodermal Tumors

Brain and Central Nervous System Tumors | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Active, not recruiting

Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy

Brain and Central Nervous System Tumors | Ototoxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapsed Malignant Brain Tumors or Newly Diagnosed Brain Stem Glioma

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer

Sarcoma | Pain | Lymphoma | Kidney Cancer | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Brain and Central Nervous System Tumors | Mucositis | Chordoma | Neuroblastoma

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Completed

Combination Chemotherapy and Radiation Therapy in Treating Patients With Germ Cell Tumors in the Brain

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy and Thalidomide in Treating Younger Patients Undergoing Surgery For Newly Diagnosed Liver Cancer

Liver Cancer

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Metastatic Medulloblastoma Who Have Undergone Surgery

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy, Surgery, and Radiation Therapy in Treating Infants With Neuroblastoma

Neuroblastoma

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

High-Dose Methotrexate in Treating Young Patients With Residual Ependymoma

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Cisplatin and Temozolomide in Treating Young Patients With Malignant Glioma

Brain and Central Nervous System Tumors

France, United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

CYP3A5 Gene as a Risk Factor for Kidney Damage in Young Patients With Cancer Treated With Ifosfamide

Sarcoma | Unspecified Childhood Solid Tumor, Protocol Specific | Chemotherapeutic Agent Toxicity

Ireland, United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Treatment Outcome and Quality of Life in Patients With Pediatric Extra-Cranial Germ Cell Tumors Previously Treated on Clinical Trial CCLG-GC-1979-01 or CCLG-GC-1989-01

Infertility | Ovarian Cancer | Sexual Dysfunction | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Gastrointestinal Complications | Urinary Complications | Pulmonary Complications | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

Ireland, United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Isotretinoin in Treating Young Patients With High-Risk Neuroblastoma

Neuroblastoma

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter

Infection

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy With or Without Radiation Therapy and Peripheral Stem Cell Transplant in Treating Children With Hodgkin's Lymphoma

Lymphoma

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Radiation Therapy Followed By Combination Chemotherapy in Treating Young Patients With Supratentorial Primitive Neuroectodermal Tumors

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Radiation Therapy or Combination Chemotherapy in Treating Young Patients With Hodgkin's Lymphoma

Lymphoma
Children's Cancer and Leukaemia Group

Unknown

Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney

Kidney Cancer

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Observation of Young Patients With Localized Neuroblastoma Who Have Undergone Surgery Only

Neuroblastoma | Long-term Effects Secondary to Cancer Therapy in Children
Children's Cancer and Leukaemia Group

Unknown

Topotecan, Vincristine, and Doxorubicin in Treating Young Patients With Refractory Stage 4 Neuroblastoma

Neuroblastoma

United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Evaluating the Side Effects and How Well Anticancer Drugs Work in Very Young Patients With Cancer

Unspecified Childhood Solid Tumor, Protocol Specific

Ireland, United Kingdom
Children's Cancer and Leukaemia Group

Unknown

Radiation Therapy and Tamoxifen in Treating Children With Newly Diagnosed Brain Stem Glioma

Brain and Central Nervous System Tumors

United Kingdom, Ireland
Children's Cancer and Leukaemia Group

Unknown

Combination Chemotherapy in Treating Infants With Newly Diagnosed Neuroblastoma Who Are Undergoing Surgery With or Without Autologous Bone Marrow or Peripheral Stem Cell Transplant

Neuroblastoma
Children's Cancer and Leukaemia Group

Completed

Combination Chemotherapy in Treating Young Patients Who Are Undergoing Surgery and an Autologous Bone Marrow Transplant for Disseminated Neuroblastoma

Neuroblastoma
Birmingham Women's and Children's NHS Foundation...
Children's Cancer and Leukaemia Group

Not yet recruiting

Nephrogreen. Appearances of Exvivo Renal Tumours Under Near-infrared (Nephrogreen)

Renal Cancer | Wilms Tumor

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI); Children's Cancer and Leukaemia Group; Societe...

Completed

TITLE:Less Intensive Therapy for Children With Non-Hodgkin's Lymphoma

Lymphoma | Leukemia

France, United Kingdom
South China Children's Leukemia Group

Completed

A Study for Improving the Outcome of Childhood Acute Promyeloid Leukemia

Childhood Acute Promyelocytic Leukemia

China
Australasian Leukaemia and Lymphoma Group

Recruiting

A Phase 2 Trial of GlOfitamab anD pIrtobrutinib in Mantle Cell Lymphoma Patients With Prior BTK Inhibitor Exposure. (GOlDiLOX)

Mantle Cell Lymphoma | Mantle Cell Lymphoma Refractory

Australia
Australasian Leukaemia and Lymphoma Group

Not yet recruiting

Epcoritamab (Epcor)-Containing Combination Salvage Therapy Followed by ASCT & Epcor Consolidation in Patients With Relapsed LBCL

High-grade B-cell Lymphoma | DLBCL - Diffuse Large B Cell Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | DLBCL, Nos Genetic Subtypes | High Grade B-Cell Lymphoma, Not Otherwise Specified | Follicular Large Cell Lymphoma, Relapsed | Follicular Large Cell Lymphoma

Clinical Trials Sponsored by Children's Cancer and Leukaemia Group

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