Clinical Trials Sponsored by Clatterbridge Centre for Oncology NHS Foundation Trust

Total 99 results

The Clatterbridge Cancer Centre NHS Foundation...

Recruiting

Nivolumab in Combination With TACE/TAE for Patients With Intermediate Stage HCC (TACE-3)

Hepatocellular Carcinoma

United Kingdom
The Clatterbridge Cancer Centre NHS Foundation...

Unknown

Investigation of an Abdominal Compression Device (ACE02)

Cancer of Stomach | Cancer, Lung

United Kingdom
The Clatterbridge Cancer Centre NHS Foundation...

Unknown

Magnetic Resonance Imaging for Lung Radiotherapy (MRI Lung)

Cancer | Lung Cancer

United Kingdom
The Clatterbridge Cancer Centre NHS Foundation...

Completed

BIOPROP20: Biologically Optimised IMRT for Prostate Radiotherapy Hypofractionated Radiotherapy With Intra-prostatic Boosts to Tumour Nodules in Men With Intermediate and High Risk Prostate Cancer (BIOPROP20)

Prostate Cancer

United Kingdom
The Clatterbridge Cancer Centre NHS Foundation...
University of Liverpool

Unknown

A Phase II Clinical Trial of Cediranib and Olaparib Maintenance in Advanced Recurrent Cervical Cancer (COMICE)

Cervical Cancer

United Kingdom
The Clatterbridge Cancer Centre NHS Foundation...
University of Liverpool

Not yet recruiting

Phase II Study of the Use of Neoadjuvant Cabazitaxel With Hormonal Treatment in Patients Operable Prostate Cancer, Assess the Efficacy and Toxicity of Cabazitaxel, and Explore Potential Predictive and Prognostic Markers of Clinical Outcome (CHROME)

Prostate Cancer
The Clatterbridge Cancer Centre NHS Foundation...
Pfizer; Cancer Research UK

Completed

A Phase II Study of Sunitinib Versus Dacarbazine in the Treatment of Patients With Metastatic Uveal Melanoma (SUAVE)

Metastatic Uveal Melanoma

United Kingdom
University of Liverpool
Liverpool University Hospitals NHS Foundation Trust; Liverpool Heart and Chest... and other collaborators

Recruiting

A Platform Study for solId orgaN CancERs (PINCER)

Cancer | Surgery

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust
National Institute for Health Research, United Kingdom; The Clatterbridge Cancer...

Recruiting

CITRuS Stage 1; Feasibility (CITRuS1)

Colorectal Cancer

United Kingdom
The Clatterbridge Cancer Centre NHS Foundation...
University of Liverpool Cancer Research Centre

Not yet recruiting

Cardiopulmonary Exercise Testing: An Assessment of Patients Fitness for Palliative Chemotherapy for Pancreatic Cancer (CPET-Panc)

Pancreatic Cancer
The Clatterbridge Cancer Centre NHS Foundation...
Bristol-Myers Squibb; University of Liverpool

Active, not recruiting

CA209-891: Neoadjuvant and Adjuvant Nivolumab as Immune Checkpoint Inhibition in Oral Cavity Cancer (NICO)

Squamous Cell Carcinoma of the Oral Cavity

United Kingdom
The Clatterbridge Cancer Centre NHS Foundation...
Cancer Research UK; University of Liverpool

Suspended

Acelarin First Line Randomised Pancreatic Study (ACELARATE)

Pancreatic Neoplasms | Pancreatic Acinar Carcinoma

United Kingdom
The Clatterbridge Cancer Centre NHS Foundation...
University of Oxford; University of Edinburgh; University of Liverpool

Unknown

CCP Cancer UK Companion Study

Cancer | Covid19
Cancer Vaccines Limited
Cancer Research UK; Liverpool University Hospitals NHS Foundation Trust; University... and other collaborators

Active, not recruiting

Investigation of a Therapeutic Vaccine (ACIT-1) in Cancer

Neoplasms | Cancer

United Kingdom
University of Cambridge
The Leeds Teaching Hospitals NHS Trust; Cambridge University Hospitals NHS... and other collaborators

Active, not recruiting

Closed Loop From Onset in Type 1 Diabetes (CLOuD)

Diabetes Mellitus | Type 1 Diabetes

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; King's College Hospital NHS Trust; Cardiff University; Northern... and other collaborators

Terminated

A Multicentre randomiSed Controlled TRial of IntraVEnous Immunoglobulin Versus Standard Therapy for Transverse Myelitis (STRIVE)

Neuromyelitis Optica | Myelitis, Transverse

United Kingdom
Greater Manchester Mental Health NHS Foundation...
Manchester University NHS Foundation Trust; University of Manchester; Anna Freud... and other collaborators

Completed

Enhancing Referrals to Child and Adolescent Mental Health Services: EnCAMHS (EnCAMHS)

Mental Health Issue

United Kingdom
Liverpool Heart and Chest Hospital NHS Foundation...
Liverpool Centre for Cardiovascular Science

Recruiting

Telehealth Interventions for Cardiac Surgery (TICS)

Coronary Artery Disease | Surgical Complication | Cardiac Valve Disease

United Kingdom
University of Bath
National Institute for Health Research, United Kingdom; Oxford Health NHS Foundation... and other collaborators

Not yet recruiting

Compassion Project: Developing an Empathy-Based Stress Intervention

Reduction of Empathy-Based Stress in Healthcare Staff
Manchester University NHS Foundation Trust
University College, London; Sheffield Teaching Hospitals NHS Foundation Trust; University of Leicester and other collaborators

Recruiting

UK Heart Failure With Preserved Ejection Fraction (UK HFpEF)

Heart Failure With Preserved Ejection Fraction (HFpEF)

United Kingdom
Manchester University NHS Foundation Trust
University College, London; University Hospital Southampton NHS Foundation... and other collaborators

Recruiting

Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate (SLUMBRS2)

Obstructive Sleep Apnea | Cleft Palate

United Kingdom
Odense University Hospital
Moorfields Eye Hospital NHS Foundation Trust; Center for Eye Research Australia

Completed

Incidence of Retinopathy and Associated Risk Factors in Children and Young Adults With Type 1 Diabetes in Denmark (DCPD1987)

Diabetic Retinopathy | Type 1 Diabetes

Denmark
Royal Marsden NHS Foundation Trust
Wellcome Trust; Institute of Cancer Research, United Kingdom; Biomedical Research...

Completed

A Phase I, First in Man Study to Evaluate the Safety and Tolerability of a panRAF Inhibitor (CCT3833/BAL3833)in Patients With Solid Tumours (PanRAF)

Melanoma | Cancer

United Kingdom
Oxford Brookes University
National Institute for Health Research, United Kingdom; Royal Berkshire NHS... and other collaborators

Completed

Exercise Interventions in Parkinson's Disease

Parkinson's Disease

United Kingdom
Walton Centre NHS Foundation Trust
University of Liverpool; National Institute for Health Research, United Kingdom

Not yet recruiting

Timing to Restart Direct Oral Anticoagulants After Traumatic Intracranial Haemorrhage (RESTARTtlCrH)

Traumatic Intracranial Haemorrhage
Great Ormond Street Hospital for Children NHS Foundation...
Imperial College London; Barts & The London NHS Trust; Intensive Care National...

Completed

FIRST-line Support for Assistance in Breathing in Children (FIRST-ABC) Feasibility Study (FIRST-ABC)

Hypoxia | Respiratory Acidosis | Moderate/Severe Respiratory Distress

United Kingdom
University of Ulster
Belfast Health and Social Care Trust; Sheffield Teaching Hospitals NHS Foundation... and other collaborators

Recruiting

Awareness Detection and Communication in Disorders of Consciousness

Stroke | Paralysis | Motor Neuron Disease | Disorder of Consciousness | Physical Disability

United Kingdom, Ireland
Centre Hospitalier Universitaire Vaudois
University College, London; Great Ormond Street Hospital for Children NHS Foundation...

Not yet recruiting

Repurposing Empagliflozin and Dapagliflozin for Paediatric Heart Failure: Translational Approach and Dose Rationale

Heart Failure

Switzerland, United Kingdom
University Hospitals Bristol and Weston NHS Foundation...
Bosum Buddies; Friends of the Bristol Haematology and Oncology Centre

Terminated

Multiple Oncological Serial Scans Study (MOSS)

Breast Cancer

United Kingdom
UMC Utrecht
Karolinska University Hospital; Erasmus Medical Center; Great Ormond Street Hospital... and other collaborators

Not yet recruiting

Primary Posterior Tracheopexy Prevents Tracheal Collapse (PORTRAIT)

Oesophageal Atresia | Tracheomalacia | Oesophageal Atresia With Tracheo-Oesophageal Fistula
Vitaflo International, Ltd
Radboud University Medical Center; Great Ormond Street Hospital for Children...

Completed

Evaluation of PDE MAX (PDE MAX)

Pyridoxine Dependant Epilepsy

Netherlands, United Kingdom
Cambridge University Hospitals NHS Foundation Trust
National Institute for Health Research, United Kingdom; Wolfson Brain Imaging...

Recruiting

Quantiative MRI and Myelin-PET for the Assessment of Degenerative Cervical Myelopathy (IMAGE-DCM)

Cervical Spondylosis With Myelopathy | Degenerative Cervical Myelopathy

United Kingdom
University of Oxford
London School of Hygiene and Tropical Medicine; The Leeds Teaching Hospitals... and other collaborators

Completed

Temporal Artery Biopsy vs ULtrasound in Diagnosis of GCA (TABUL) (TABUL)

Giant Cell Arteritis

Ireland, United Kingdom, Germany, Norway, Portugal
Great Ormond Street Hospital for Children NHS Foundation...
University College, London; University of Southampton; University Hospital Southampton... and other collaborators

Completed

Conservative Versus Liberal Oxygenation Targets in Critically Ill Children (Oxy-PICU)

Hypoxia | Pediatric ALL | Critical Care

United Kingdom
Smart Matrix Limited
Welsh Centre for Burns and Plastic Surgery, Swansea, UK; Queen Victoria Hospital...

Terminated

Safety, Tolerability and Performance of SmartMatrix Dermal Replacement Scaffold

Basal Cell Carcinoma | Squamous Cell Carcinoma

United Kingdom
Nisha Acharya
Children's Hospital of Philadelphia; University of Miami; National Eye Institute... and other collaborators

Active, not recruiting

Adalimumab in JIA-associated Uveitis Stopping Trial (ADJUST)

Uveitis | JIA

United States, Australia, United Kingdom
University of Cambridge
University of Colorado, Denver; University College London Hospitals; Juvenile... and other collaborators

Completed

Home Testing of Day and Night Closed Loop With Pump Suspend Feature (APCam11)

Glucose Metabolism Disorders | Autoimmune Diseases | Diabetes Mellitus | Endocrine System Diseases | Diabetes Mellitus, Type 1

United States, United Kingdom
University of Birmingham
University Hospital Birmingham NHS Foundation Trust; Dowager Countess Eleanor... and other collaborators

Unknown

Understanding Acute Sarcopenia

Sarcopenia

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Crohn's & Colitis UK; Sheffield Centre for Health and...

Recruiting

Early Bowel Resection for Terminal Ileal Crohn's Disease (E-BRIC)

Crohn Disease

United Kingdom
Naiem Moiemen
University of Birmingham; The Scar Free Foundation Centre for Conflict Wound... and other collaborators

Recruiting

Mechanistic Basis of Ablative Carbon Dioxide Laser in Treating Hypertrophic Scars (SMOOTH)

Burn Scar | Scar

United Kingdom
Centre Antoine Lacassagne
Karolinska Institutet; Centre Leon Berard; Hospices Civils de Lyon; Aarhus University... and other collaborators

Active, not recruiting

Safety of a Boost (CXB or EBRT) in Combination With Neoadjuvant Chemoradiotherapy for Early Rectal Adenocarcinoma (OPERA)

Rectal Neoplasms

France, United Kingdom, Denmark, Sweden
Liverpool John Moores University
University of Liverpool; Liverpool Heart and Chest Hospital NHS Foundation... and other collaborators

Recruiting

High-intensity Interval Training in Patients With Atrial Fibrillation (HIIT-AF)

Atrial Fibrillation

United Kingdom
University Hospital Birmingham NHS Foundation Trust
University of Birmingham; National Institute for Health Research, United Kingdom and other collaborators

Unknown

Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy? (D-CODE)

Vitamin D Deficiency | Crohn Disease

United Kingdom
Mount Sinai Hospital, Canada
Cambridge University Hospitals NHS Foundation Trust; University of Cambridge; Jaeb Center for Health Research and other collaborators

Completed

Continuous Glucose Monitoring in Women With Type 1 Diabetes in Pregnancy Trial (CONCEPTT)

Type 1 Diabetics Who Are Pregnant or Planning Pregnancy

Canada, United Kingdom, Spain, United States, Ireland, Italy
University of Southampton
University Hospital Southampton NHS Foundation Trust; National Institute for... and other collaborators

Recruiting

Benchmarking Integrated Care for People Living With Huntington's Disease in England (Integrate-HD)

Huntington Disease

United Kingdom
University College, London
University College London Hospitals (UCLH) NHS Foundation Trust; National Institute...

Recruiting

THIRST Alert Trial (THIRST)

Fluid Overload | Congestive Heart Failure

United Kingdom
University of Liverpool
University of Leeds; Liverpool John Moores University; Liverpool Heart and Chest... and other collaborators

Terminated

The Effects of Renal Function and Atrial Fibrillation on Lipoproteins and Clot Structure/Function (RALiC)

Atrial Fibrillation | Chronic Kidney Disease

United Kingdom
PIQUR Therapeutics AG
Royal Marsden NHS Foundation Trust; University College London Hospitals; Weill... and other collaborators

Completed

Open-Label, Non Randomized Phase 2 Study With Safety Run-In

Lymphoma, Malignant

United States, United Kingdom, Serbia, Bosnia and Herzegovina, France, Israel
Laminar Pharmaceuticals
Royal Marsden NHS Foundation Trust; Vall d'Hebron Institute of Oncology; Specialized... and other collaborators

Completed

A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours

Glioma | Other Solid Tumours

Spain, United Kingdom
University Children's Hospital, Zurich
Erasmus Medical Center; Great Ormond Street Hospital for Children NHS Foundation... and other collaborators

Completed

Endoscopic Evaluation of the Paediatric Airway After Prior Prolonged (>24 h) Tracheal Intubation

Intubation | Endoscopy

United Kingdom, Switzerland, Germany, Netherlands

Clinical Trials Sponsored by Clatterbridge Centre for Oncology NHS Foundation Trust

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