Clinical Trials Sponsored by Cleveland Clinic Lerner Research Institute

Total 1843 results

The Cleveland Clinic
Alcon Research

Completed

LASIK Flap Thickness and Visual Outcomes Using the WaveLight FS200 Femtosecond Laser (FS200)

Myopia

United States
The Cleveland Clinic
National Space Biomedical Research Institute

Terminated

Effect of Bedrest With and Without Exercise on the Heart

Bedrest

United States
The Cleveland Clinic
National Space Biomedical Research Institute

Withdrawn

Diagnostic Three Dimensional Echocardiography Study Protocol

Aortic Valve Stenosis | Aortic Valve Insufficiency

United States
The Cleveland Clinic
National Space Biomedical Research Institute

Terminated

Three Dimensional Imaging and Wireless Technologies to Enhance Medical Care in Space

Aortic Stenosis | Aortic Valve Insufficiency

United States
The Cleveland Clinic
National Space Biomedical Research Institute

Terminated

Echocardiographic Assessment of Cardiovascular Changes in Long Term Space Flight

Aortic Valve Stenosis | Aortic Valve Insufficiency

United States
Irish Clinical Outcomes in Research and Education
The Cleveland Clinic

Unknown

The 'SILVERMAN1' Trial Single Incision Laparoscopic Versus Existing Resection (Minimal Access) for Neoplasia (SILVERMAN 1)

Right Colon Tumors

Ireland
Pennington Biomedical Research Center
The Cleveland Clinic

Recruiting

Nutrition for Asthmatics With Obesity

Obesity | Asthma

United States
The Cleveland Clinic
Lumbar Spine Research Society

Terminated

Threshold Response of Lumbar Selective Nerve Root Block in Predicting Good Outcome Following Lumbar Foraminotomy

Back Pain | Radiculopathy Lumbar | Degenerative Lumbar Spinal Stenosis

United States
North Dakota State University
The Cleveland Clinic; Neuropsychiatric Research Institute

Unknown

Microbiome and Bariatric Surgery (Biobehavioral)

Weight Change, Body

United States
Bo Hu
Patient-Centered Outcomes Research Institute

Completed

ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD) (ELEKT-D)

Depression | Major Depressive Disorder | Treatment Resistant Depression | Ketamine | Psychiatric Disorder | Unipolar Depression | Major Depressive Episode | Electroconvulsive Therapy | ECT

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Terminated

Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease

Actinic Keratosis | Organ or Tissue Transplant; Complications

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Temozolomide in Treating Patients With Newly Diagnosed Anaplastic Oligodendroglioma or Mixed Oligoastrocytoma

Brain Tumor | Central Nervous System Tumors

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Epoetin Alfa in Treating Anemia in Patients Undergoing Chemotherapy for Multiple Myeloma

Multiple Myeloma | Anemia | Plasma Cell Neoplasm

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Caregiver Support in the Coping of Patients Who Are Undergoing a Donor Bone Marrow Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Psychosocial Effects of Cancer and Its Treatment

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Terminated

T-Cell Depletion, Donor Hematopoietic Stem Cell Transplant (HSCT), and T-Cell Infusions in Treating Patients With Hematologic Cancer or Other Diseases

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Precancerous/Nonmalignant Condition | Secondary Myelofibrosis | Multiple Myeloma and Malignant Plasma Cell Neoplasms

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Gemcitabine and Irinotecan in Treating Patients With Metastatic Kidney Cancer

Kidney Cancer

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Terminated

Topical Aminolevulinic Acid in Patients With Nonmelanoma Skin Cancer

Non-melanomatous Skin Cancer
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Interferon Alfa in Treating Patients With Stage IV Solid Tumors, Lymphoma, or Myeloma (IFNa)

Melanoma | Sarcoma | Lymphoma | Kidney Cancer | Breast Cancer | Multiple Myeloma | Unspecified Adult Solid Tumor, Protocol Specific

United States
The Cleveland Clinic

Unknown

Radiation Therapy in Treating Patients Who Are Undergoing Surgery to Remove a Metastatic Brain Tumor

Metastatic Cancer

United States
The Cleveland Clinic

Unknown

Combination Chemotherapy Plus Amifostine in Treating Patients With Advanced Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Drug/Agent Toxicity by Tissue/Organ

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Unknown

Perillyl Alcohol in Preventing Recurrent Breast Cancer in Women Who Have Been Treated With Surgery With or Without Adjuvant Therapy

Breast Cancer

United States
The Cleveland Clinic

Completed

Rituximab in Treating Patients With Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Lenalidomide, Docetaxel, and Carboplatin in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

VP and G-CSF With or Without Rituximab in Autologous Peripheral Stem Cell Transplant For NHL

Lymphoma

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Leukemia
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma

Malignant Mesothelioma

United States
The Cleveland Clinic
National Eye Institute (NEI)

Completed

PIONEER: Intraoperative and Perioperative OCT Study (PIONEER)

Retinal Detachment | Epiretinal Membrane | Fuchs Endothelial Dystrophy | Macular Hole

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Biological Therapy in Treating Patients With Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
The Cleveland Clinic

Completed

Combination Chemotherapy Following GM-CSF in Treating Patients With Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
The Cleveland Clinic

Withdrawn

Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Refractory Plasma Cell Neoplasm

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Imatinib Mesylate, Daunorubicin, and Cytarabine in Treating Patients With Relapsed Acute Myeloid Leukemia

Leukemia

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Cerebrospinal Fluid Levels of Erlotinib in Patients Receiving Erlotinib For Stage III Non-Small Cell Lung Cancer

Lung Cancer

United States
The Cleveland Clinic
National Eye Institute (NEI)

Recruiting

DISCOVER Study: Microscope-integrated Intraoperative OCT Study (DISCOVER)

Retinal Diseases | Retinal Detachment | Epiretinal Membrane | Fuchs Endothelial Dystrophy | Macular Hole

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

GM-CSF and Thalidomide in Treating Patients Undergoing Surgery for High-Risk Prostate Cancer

Prostate Cancer

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Terminated

Sodium Stibogluconate and Interferon in Treating Patients With Advanced Solid Tumors, Lymphoma, or Myeloma

Cancer

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Lenalidomide in Treating Patients With Advanced or Unresectable Kidney Cancer

Kidney Cancer

United States
The Cleveland Clinic

Unknown

Erlotinib in Treating Patients With Recurrent or Progressive Glioblastoma Multiforme

Brain and Central Nervous System Tumors

United States
The Cleveland Clinic

Completed

Combination Chemotherapy in Treating Patients With Multiple Myeloma

Multiple Myeloma and Plasma Cell Neoplasm

United States
National Cancer Institute (NCI)
The Cleveland Clinic

Completed

Interleukin-12 and Interferon Alfa in Treating Patients With Metastatic Kidney Cancer or Malignant Melanoma

Kidney Cancer | Melanoma (Skin)

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Docetaxel and Temozolomide in Treating Patients With Metastatic Cancer

Unspecified Adult Solid Tumor, Protocol Specific

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Completed

Arzoxifene or Tamoxifen in Preventing Breast Cancer in Premenopausal Women at High Risk for Breast Cancer

Breast Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2)
The Cleveland Clinic
National Human Genome Research Institute (NHGRI); Indiana University

Completed

Ensuring Patients' Informed Access to Noninvasive Prenatal Testing (NEST)

Pregnancy Complications | Genetic Disease | Genetic Syndrome | Prenatal Disorder | Prenatal Maternal Abnormality

United States
The Cleveland Clinic
Telemedicine & Advanced Technology Research Center

Completed

Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation

Spinal Cord Injury

United States
Medical University of Vienna
The Cleveland Clinic; Population Health Research Institute

Completed

Rapydan Topical Anaesthesia for Arterial Cannulation

Arterial Catheterization

Austria, United States, Canada
The Cleveland Clinic
National Institute on Aging (NIA)

Completed

Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's Disease

Genetic Risk for Alzheimer's Disease

United States
The Cleveland Clinic
National Institute on Aging (NIA)

Recruiting

Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients

Frailty | Mobility Limitation | Hospital Acquired Condition | Weakness, Muscle

United States
The Cleveland Clinic
Yale University; Donaghue Medical Research Foundation

Active, not recruiting

Patient Priority Care for Older Adults With Multiple Chronic Conditions (PPC-CCF)

Multiple Chronic Conditions

United States
Greater Houston Retina Research
The Cleveland Clinic; Regeneron Pharmaceuticals

Completed

Intravitreal Aflibercept as Indicated by Real-Time Objective Imaging to Achieve Diabetic Retinopathy Improvement

Diabetic Retinopathy

United States
The Cleveland Clinic
Haydarpasa Numune Training and Research Hospital

Withdrawn

Effect of Local Administration of Morphine for Analgesia After Iliac Bone Graft Harvest

Autogenous Bone Grafts
The Cleveland Clinic
National Institutes of Health (NIH)

Completed

Natural History of Pearson Syndrome

Pearson Syndrome

Clinical Trials Sponsored by Cleveland Clinic Lerner Research Institute

Sponsors and Collaborators

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CROs in New Zealand

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