Clinical Trials Sponsored by Clexio Biosciences Ltd.

Total 362 results

Clexio Biosciences Ltd.

Recruiting

A Study of CLE-100 (Oral Esketamine) as an Adjunctive Treatment to Standard Antidepressants for Major Depressive Disorder (SOLEO)

Adjunctive Treatment of Major Depressive Disorder (MDD)

United States
Clexio Biosciences Ltd.

Completed

A Study of CLE-100 (Oral Esketamine) in Addition to Standard Antidepressant Drug for Major Depressive Disorder - CLEO Study

Adjunctive Treatment of Major Depressive Disorder

United States, Puerto Rico
Clexio Biosciences Ltd.

Recruiting

A Study of CLE-400 (Topical Gel) for the Treatment of Chronic Pruritus in Adult Subjects With Notalgia Paresthetica

Chronic Pruritus in Adult Subjects With Notalgia Paresthetica (NP)

United States
Anwita Biosciences
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Phase 1 First-in-human Study of JS014

Lymphoma | Solid Tumor, Adult | Neoplasm Malignant | Neoplasm, Experimental

Taiwan
Shanghai Junshi Bioscience Co., Ltd.
Iqvia Pty Ltd; TopAlliance Biosciences, Inc.

Active, not recruiting

Safety, Tolerability and Pharmacokinetics of an Anti-PD-1 Monoclonal Antibody in Subjects With Advanced Malignancies

Advanced Malignancies

United States
Chipscreen Biosciences, Ltd.

Not yet recruiting

A Study of NWY001 in Subjects With Advanced Solid Tumors

Advanced Solid Tumor

China
Chipscreen Biosciences, Ltd.

Recruiting

Pharmacokinetics of Chiglitazar in Subjects With Renal Impairment and Normal Renal Function

Renal Impairment

China
Chipscreen Biosciences, Ltd.

Recruiting

Chiauranib for Advanced or Unresectable Soft Tissue Sarcoma(STS)

Soft Tissue Sarcoma

China
Chipscreen Biosciences, Ltd.

Recruiting

A Phase II Study of Chiauranib in Combine With Capecitabine in TNBC

Triple-negative Breast Cancer

China
Chipscreen Biosciences, Ltd.

Active, not recruiting

Phase III Study of Tucidinostat in Combination With R-CHOP in Patients With Newly Diagnosed Double-Expressor DLBCL (DEB)

Diffuse Large B-cell Lymphoma

China
Chipscreen Biosciences, Ltd.

Completed

Phase Ib/II Study of Chiauranib in Patients With Small Cell Lung Cancer

Small Cell Lung Cancer

China
Chipscreen Biosciences, Ltd.

Active, not recruiting

Trial of Chidamide in Combination With Envafolimab in Patients With PD-1 Inhibitor Resistant Advanced NSCLC.

Non Small Cell Lung Cancer

China
Liminal BioSciences Ltd.

Terminated

A Healthy Volunteer Study to Compare Fezagepras (PBI-4050) With Sodium Phenylbutyrate

Hyperammonemia

United Kingdom
Chipscreen Biosciences, Ltd.

Completed

Trial of Chidamide in Combination With Exemestane in Patients With Advanced Breast Cancer

Breast Cancer

China
Chipscreen Biosciences, Ltd.

Completed

Chiauranib in Combination With Chemotherapy in Patients With Ovarian Cancer

Ovarian Cancer

China
Liminal BioSciences Ltd.

Terminated

Study to Evaluate Safety, Efficacy of PBI-4050 & Its Effect on Relevant Biomarkers in T2DM Patients With Metabolic Syndrome

Type 2 Diabetes Mellitus | Metabolic Syndrome

Canada
Chipscreen Biosciences, Ltd.

Completed

Study of Chiglitazar Compare With Placebo in Type 2 Diabetes Patients (CMAP)

Type 2 Diabetes

China
Chipscreen Biosciences, Ltd.

Completed

Clinical Trial of Chidamide Combined With CHOP in Peripheral T-cell Lymphoma Patients

Peripheral T-cell Lymphoma

China
Liminal BioSciences Ltd.

Completed

A Phase 2 Study to Evaluate the Safety and Tolerability of PBI-4050 in Patients With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis (IPF)

Canada
Prothena Biosciences Ltd.

Terminated

Study in Subjects With Light Chain (AL) Amyloidosis

AL Amyloidosis

United States, Spain, Australia, Italy, Germany, Austria, Greece, France, Israel, United Kingdom
Clasado Biosciences Ltd

Withdrawn

Clinical Trial of CBS-2004 in Prevention of Travelers' Diarrhea

Traveler's Diarrhea
Chipscreen Biosciences, Ltd.

Completed

Phase I Study of Chiauranib in Patients With Advanced Solid Tumors

Solid Tumors

China
Chipscreen Biosciences, Ltd.

Completed

Chidamide in Combination With Carboplatin and Paclitaxel in Advanced Non-small Cell Lung Cancer

Non-small-cell Lung Cancer

China
Coherus Biosciences, Inc.
Shanghai Junshi Bioscience Co., Ltd.; Medpace, Inc.

Active, not recruiting

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

Hepatocellular Carcinoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor

United States
Modern Biosciences Ltd

Not yet recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Chipscreen Biosciences, Ltd.

Recruiting

A Study of Tucidinostat Combined With Tislelizumab as First-line Treatment in Advanced NSCLC

Non Small Cell Lung Cancer

China
Chipscreen Biosciences, Ltd.

Recruiting

Pharmacokinetics of Chiglitazar in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Impairment

China
Chipscreen Biosciences, Ltd.

Recruiting

Mass Balance Study of [14C]Chiauranib

Small Cell Lung Cancer

China
Prothena Biosciences Ltd.

Recruiting

A Study to Evaluate the Efficacy and Safety of Birtamimab in Mayo Stage IV Patients With AL Amyloidosis (AFFIRM-AL)

Light Chain (AL) Amyloidosis

United States, Korea, Republic of, Australia, Denmark, France, Italy, Spain, Israel, Taiwan, Austria, Canada, Czechia, Germany, Greece, Hungary, Japan, Netherlands, Poland, Portugal, Turkey, United Kingdom, Belgium, Ireland
Chipscreen Biosciences, Ltd.

Recruiting

Chiglitazar Added to Metformin for Type 2 Diabetes

Type 2 Diabetes

China
Chipscreen Biosciences, Ltd.

Completed

A Clinical Trial of CS12192 in Healthy Subjects

Healthy

China
Modern Biosciences Ltd

Completed

Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA

Rheumatoid Arthritis

Bosnia and Herzegovina, Bulgaria, Chile, Czechia, Guatemala, Mexico, Poland, Serbia
Liminal BioSciences Ltd.

Completed

A Healthy Volunteer Study of PBI-4050

Fibrosis | Inflammation

United Kingdom
Liminal BioSciences Ltd.

Terminated

Study of Safety, Tolerability & Efficacy in Cystic Fibrosis Patients With Abnormal Glucose Tolerance

Cystic Fibrosis

Canada
Chipscreen Biosciences, Ltd.

Completed

Study of Chiglitazar Compare With Sitagliptin in Type 2 Diabetes Patients (CMAS)

Type 2 Diabetes

China
Chipscreen Biosciences, Ltd.

Terminated

Study of Chiauranib in Relapsed/Refractory Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma

China
Prothena Biosciences Ltd.

Terminated

Open-label Extension Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis (OLE)

AL Amyloidosis

United States
Prothena Biosciences Ltd.

Completed

The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis (PRONTO)

AL Amyloidosis

United States, Spain, Australia, Germany, United Kingdom, France, Greece, Israel, Italy, Austria
Emalex Biosciences Inc.
PPD; Clario

Completed

Thorough QT/QTc Study to Evaluate the Effects of Ecopipam (EBS-101) on Cardiac Repolarization

QT/QTc

United States
Chipscreen Biosciences, Ltd.

Recruiting

A Study of CS23546 in Subjects With Advanced Tumors

Advanced Tumors

China
Chipscreen Biosciences, Ltd.

Not yet recruiting

A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic Profiles and Food Effect of CS32582 Capsules

Healthy

China
Modern Biosciences Ltd

Recruiting

A Study to Investigate Leramistat in Patients With IPF

Idiopathic Pulmonary Fibrosis

United States, United Kingdom, Israel, France, Germany, Greece, Hungary, Italy, Spain
Chimagen Biosciences, Ltd

Recruiting

First-in-Human (FIH) Trial of 1A46 in Subjects With Advanced CD20 and/or CD19 Positive B-cell Hematologic Malignancies

Non-Hodgkin's Lymphoma (Disorder) | Acute Lymphoid Leukemia, Disease (Disorder)

United States
Chipscreen Biosciences, Ltd.

Recruiting

Chiauranib for Advanced Solid Malignant Tumors and Relapsed/Refractory SCLC. (SCLC)

Small Cell Lung Cancer | Advanced Solid Malignant Tumor

United States
Chipscreen Biosciences, Ltd.

Recruiting

A Phase II Clinical Trial of Chiglitazar for NASH

NASH

China
Chipscreen Biosciences, Ltd.

Recruiting

Chiauranib Plus Weekly Paclitaxel in Patients With Platinum-refractory or Platinum-resistant Recurrent Ovarian Cancer (CHIPRO)

Ovarian Cancer | Relapsed or Refractory | Chiauranib | Paclitaxel

China
Chipscreen Biosciences, Ltd.

Recruiting

Phase 3 Clinical Study of Chiauranib Capsule in Patients With Small-cell Lung Cancer

Small Cell Lung Cancer

China
Prothena Biosciences Ltd.

Terminated

The VITAL Amyloidosis Study, a Global Phase 3, Efficacy and Safety Study of NEOD001 in Patients With AL Amyloidosis (VITAL)

Primary Systemic (AL) Amyloidosis

United States, Spain, Israel, Canada, Poland, Netherlands, France, Germany, United Kingdom, Belgium, Denmark, Greece, Australia, Austria, Italy
Chipscreen Biosciences, Ltd.

Completed

Drug-Drug Interaction Study of Chiglitazar in Healthy Subjects.

T2DM

China
Leadiant Biosciences Ltd.

Completed

Safety and Efficacy of CDCA in CTX Chenodeoxycholic Acid (CDCA) in Patients Affected by Cerebrotendinous Xanthomatosis (CTX)

Cerebrotendinous Xanthomatoses

Clinical Trials Sponsored by Clexio Biosciences Ltd.

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