Clinical Trials Sponsored by Cogent Biosciences, Inc.

Total 788 results

Cogent Biosciences, Inc.

Recruiting

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

Metastatic Cancer | Advanced Gastrointestinal Stromal Tumors

United States, Korea, Republic of, Spain, United Kingdom, Australia, France, Italy, Netherlands, Taiwan, Germany, Denmark, Hong Kong, Canada, Sweden, Norway, Mexico, Czechia, Argentina, Hungary, Brazil, Chile, Poland
Cogent Biosciences, Inc.

Terminated

Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers

Solid Tumor | HER-2 Protein Overexpression

United States
Cogent Biosciences, Inc.

Recruiting

(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis

Mastocytosis | Mastocytosis, Systemic | SSM | Mastocytosis, Indolent

United States, Italy, Canada, Australia, Spain, Switzerland, Norway, United Kingdom, Belgium, Poland, Netherlands, Germany, France, Czechia, Greece, Ireland
Cogent Biosciences, Inc.

Terminated

Long-Term Follow-Up Study of Subjects Treated With ACTR T Cell Product

Multiple Myeloma | Solid Tumor | HER-2 Protein Overexpression | B Cell Lymphomas

United States
Cogent Biosciences, Inc.

Terminated

Study of ACTR707 in Combination With Rituximab in Subjects With Relapsed or Refractory B Cell Lymphoma

Lymphoma

United States
Cogent Biosciences, Inc.

Completed

Study of ACTR087 in Subjects With Relapsed or Refractory B-cell Lymphoma

Lymphoma

United States
Cogent Biosciences, Inc.

Recruiting

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Advanced Systemic Mastocytosis (AdvSM) | SM With an Associated Hematologic Neoplasm (SM-AHN) | Mast Cell Leukemia (MCL) | Aggressive Systemic Mastocytosis (ASM)

United States, Norway, Spain, Australia, Switzerland, Germany, Belgium, Netherlands, Canada, France, United Kingdom, Austria, Italy
Cogent Biosciences, Inc.
Plexxikon

Completed

CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors

Gastrointestinal Stromal Tumors

United States
Cogent Biosciences, Inc.
Seagen Inc.

Terminated

Study of ACTR087 in Combination With SEA-BCMA in Subjects With Relapsed or Refractory Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Multiple Myeloma in Relapse

United States
Coherus Biosciences, Inc.
Shanghai Junshi Bioscience Co., Ltd.; Medpace, Inc.

Active, not recruiting

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

Hepatocellular Carcinoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor

United States
AbSolutions Med Inc.
Cogent Technologies Corporation

Recruiting

Abdominal Wall Closure After Laparotomy in Oncologic Surgery (REBUILD)

Laparotomy

Colombia
Cugene Inc.

Recruiting

A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Autoimmune | SLE (Systemic Lupus)

United States
LigaChem Biosciences, Inc.
AntibodyChem Biosciences, Inc.

Recruiting

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

Advanced Solid Tumors

United States, Canada
Vogenx, Inc.

Active, not recruiting

Effect of Mizagliflozin Repeat Dosing on Adverse Events and Postprandial Glucose Excursions

Postbariatric Hypoglycemia

United States
Vogenx, Inc.

Completed

Effect of Mizagliflozin on Postprandial Glucose and Insulin in Post-Bariatric Hypoglycemia Subjects

Postbariatric Hypoglycemia

United States
Cugene Inc.

Active, not recruiting

A Phase Ia Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneously Administered CUG252 in Normal Healthy Volunteers

Systemic Lupus Erythematosus

United States
AbSolutions Med Inc.
Cogent Technologies Corporation

Not yet recruiting

The REBUILD Trial: Closure of the Abdominal Wall

Surgical Incision

Israel
American Regent, Inc.

Not yet recruiting

Tralement Versus a Fixed-dose Trace Element Combination Product of Zinc, Copper, and Selenious Acid to Evaluate Product Safety in Pediatric Patients >3 to 17 Years of Age Requiring Long-term Parenteral Nutrition

Manganese Safety in Pediatric Patients
Sagent Pharmaceuticals Inc.

Completed

Camostat Efficacy vs. Placebo for Outpatient Treatment of COVID-19 (CAMELOT)

COVID-19

United States
American Regent, Inc.

Completed

Placebo-Controlled Study to Investigate the Efficacy & Safety of Injectafer in the Treatment of RLS

Restless Legs Syndrome (RLS)

United States
American Regent, Inc.

Completed

Comparison of Safety and Efficacy of Intravenous Iron Versus Oral Iron in Chronic Renal Failure Subjects With Anemia

Anemia

United States
American Regent, Inc.

Completed

Safety and Efficacy of a Hematinic Agent in the Treatment of Postpartum Patients

Postpartum Anemia

United States
American Regent, Inc.

Completed

VIT45 Versus Oral Iron in the Treatment of Anemia in Non-Dialysis Dependent Chronic Kidney Disease

Anemia

United States
American Regent, Inc.

Completed

Safety and Tolerability of a Single Dose of FCM vs. Standard of Care in Treating Iron Deficiency Anemia

Anemia

United States
American Regent, Inc.

Completed

Safety and Tolerability of Ferric Carboxymaltose (FCM) Versus Standard of Care in Treating Iron Deficiency Anemia

Anemia

United States
American Regent, Inc.

Completed

Hypophosphatemia With Ferric Carboxymaltose Vs. Iron Dextran in Iron Deficiency Secondary to Heavy Uterine Bleeding

Iron Deficiency Anemia
American Regent, Inc.

Completed

Taxoprexin Plus Carboplatin Treatment for Advanced Lung Cancer

Non-Small Cell Lung Cancer

United States
American Regent, Inc.

Completed

Comparison of Oral Iron With IV Iron in Patients With Anemia of Chronic Renal Failure Not on Dialysis

Anemia
American Regent, Inc.

Completed

Pharmacokinetic Study of Intravenous Iron Sucrose in Adolescents on Hemodialysis or Peritoneal Dialysis Receiving Epoetin

Anemia
American Regent, Inc.

Completed

Taxoprexin Treatment for Advanced Skin Melanoma

Metastatic Melanoma
American Regent, Inc.

Unknown

Trial to Evaluate the Utility of Serum Hepcidin Levels to Predict Response to Oral or IV Iron and to Compare Safety, Effect on Quality of Life, and Resource Utilization of Injectafer vs Intravenous Standard of Care for the Treatment of IDA in an Infusion Center Setting

Iron Deficiency Anemia (IDA)
American Regent, Inc.

Terminated

Randomized Double Blind Placebo Controlled Trial of Sodium Thiosulfate for the Treatment of Pain Associated With Calcific Uremic Arteriolopath

Calciphylaxis | Calcific Uremic Arteriolopathy

United States
American Regent, Inc.

Completed

Study of the Safety, Tolerability and Analgesic Efficacy of Multiple Doses of Ketorolac Tromethamine (IN) for Postoperative Pain

Postoperative Pain

New Zealand
IGM Biosciences, Inc.

Recruiting

A Study of Imvotamab in Severe Systemic Lupus Erythematosus

Systemic Lupus Erythematosus | Lupus Erythematosus

United States, Korea, Republic of, Poland
Neodyne Biosciences, Inc.

Recruiting

De-tensioning Patch, in Subjects With Type 1 Diabetes and Lipohypertrophy

Insulin Resistance | Lipohypertrophy

Germany
Arcus Biosciences, Inc.

Recruiting

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers (ARC-25)

Cervical Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Bladder Cancer | Advanced Cancer | Non-Small Cell Lung Cancer (NSCLC) | Advanced Malignancies | Renal Cell Carcinoma (RCC) | Triple Negative Breast Cancer (TNBC) | Head and Neck Squamous Cell Carcinoma (HNSCC) | Gastroesophageal-junction...

United States
Avidity Biosciences, Inc.

Recruiting

Phase 1/2 Study of AOC 1020 in Adults With Facioscapulohumeral Muscular Dystrophy (FSHD) (FORTITUDE)

Muscular Dystrophies | Muscular Dystrophy, Facioscapulohumeral | FSHD | Facio-Scapulo-Humeral Dystrophy | FMD | Facioscapulohumeral Muscular Dystrophy 1 | FSHD2 | FSHD1 | FMD2 | Fascioscapulohumeral Muscular Dystrophy | Fascioscapulohumeral Muscular Dystrophy Type 1 | Fascioscapulohumeral Muscular Dystrophy... and other conditions

United States, United Kingdom, Canada
Tyra Biosciences, Inc

Recruiting

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations (SURF301)

Solid Tumor | Bladder Cancer | Advanced Solid Tumor | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Solid Tumor, Adult | FGFR3 Gene Mutation | Urinary Tract Cancer | Locally Advanced Urothelial Carcinoma | Advanced Urothelial Carcinoma | Non-muscle-invasive Bladder Cancer | FGFR3 Gene Alteration | Urinary... and other conditions

Australia, United States, France, Spain
Arcus Biosciences, Inc.

Recruiting

A Phase 1 Study of AB521 in Renal Cell Carcinoma and Other Solid Tumors (ARC-20)

Clear Cell Renal Cell Carcinoma | Solid Tumors

Korea, Republic of, United States
LegoChem Biosciences, Inc

Recruiting

A Phase 2a Study, Effect of Vancomycin With vs Without Delpazolid (LCB01-0371) in Patients With MRSA Bacteremia

MRSA Bacteremia

Korea, Republic of
Senhwa Biosciences, Inc.

Recruiting

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

Advanced Solid Tumor

United States, Canada
FlightPath Biosciences, Inc.

Recruiting

Biomarker Study of Previously Treated Lyme Disease Volunteers in Comparison to Healthy Volunteers

Lyme Disease

United States
Precision BioSciences, Inc.

Recruiting

Dose-escalation Study of Safety of PBCAR19B in Participants With CD19-expressing Malignancies

Hematologic Malignancy | CD19 Expressing Malignancies

United States
IGM Biosciences, Inc.

Recruiting

Phase 1a/1b Study of Aplitabart (IGM-8444) Alone or in Combination in Participants With Relapsed, Refractory, or Newly Diagnosed Cancers

Sarcoma | Acute Myeloid Leukemia | Colorectal Cancer | Solid Tumor | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma | Chondrosarcoma | Small Lymphocytic Lymphoma

United States, Korea, Republic of, France, Spain, Australia
LigaChem Biosciences, Inc.

Active, not recruiting

Study to Evaluate the Efficacy of Delpazolid as Add-on Therapy in Refractory Mycobacterium Abscessus Complex

Mycobacterium Abscessus Infection | Nontuberculous Mycobacterium Infection

Korea, Republic of
Scioto Biosciences, Inc.

Completed

28-Day Daily-dose Crossover Study of the Safety and Tolerability of SB-121 (Lactobacillus Reuteri With Sephadex® and Maltose) in Subjects, Ages 15 to 45 Years, Diagnosed With Autistic Disorder

Autistic Disorder

United States
Avidity Biosciences, Inc.

Completed

Study of AOC 1001 in Adult Myotonic Dystrophy Type 1 (DM1) Patients (MARINA)

Myotonic Dystrophy | Myotonic Disorders | Myotonic Dystrophy Type 1 (DM1) | Myotonic Dystrophy 1 | Myotonic Muscular Dystrophy | DM1 | Dystrophy Myotonic | Steinert Disease

United States
Senhwa Biosciences, Inc.

Completed

A Study of Silmitasertib (CX-4945) in Healthy Subject

COVID-19

Taiwan
Aptose Biosciences Inc.

Active, not recruiting

A Study of CG-806 in Patients With Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas

Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
Pulse Biosciences, Inc.

Completed

CellFX Comparison to Cryosurgery in Cutaneous Non-Genital Common Warts

Warts | Warts Hand | Verruca

United States

Clinical Trials Sponsored by Cogent Biosciences, Inc.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Zimbabwe

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations