Clinical Trials Sponsored by Cogentus Pharmaceuticals

Total 19575 results

Cogentus Pharmaceuticals

Completed

Pharmacodynamics of CGT 2168 Compared With Plavix®

Healthy

United States
Cogentus Pharmaceuticals

Terminated

Clopidogrel and the Optimization of Gastrointestinal Events (COGENT-1) (COGENT-1)

Myocardial Infarction | Coronary Artery Disease | Acute Coronary Syndrome | Percutaneous Coronary Intervention

United States, France, Canada, Australia, Poland, Germany, Italy, Mexico, Romania, Slovakia, Hungary, Czech Republic, Chile, Bulgaria, Puerto Rico, Ukraine
CoMentis

Terminated

Safety and Efficacy of ATG003 in Patients With Wet Age-Related Macular Degeneration (AMD)

Macular Degeneration

Brazil, Mexico, Czech Republic, Poland, Russian Federation, Ukraine
CoMentis

Completed

Safety and Efficacy of GTS21 in Adults With Attention-deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

United States
CoMentis

Completed

Safety Study of CTS21166 to Treat Alzheimer Disease (CTS)

Alzheimer's Disease

United States
CoMentis

Terminated

Safety and Preliminary Efficacy Study of Nicotine Gel to Treat Diabetic Foot Ulcers

Diabetic Foot Ulcers

United States
CoMentis

Completed

GTS21-201 for Alzheimer Disease:GTS-21 Administered Daily for 28 Days to Participants With Probable Alzheimer's Disease

Alzheimer Disease

United States
CoMentis

Completed

Safety and Efficacy of ATG003 in Patients With AMD Receiving Anti-VEGF

Age-Related Macular Degeneration
Comenius University

Completed

Gut Microbiota Composition, Cognitive Function, and Physical Fitness in Multiple Sclerosis Patients (MSDANCE)

Sclerosis, Multiple

Slovakia
Comenius University

Terminated

Normal and Pathological Values of Postvoiding Residual Volume in Early Postpartum Period and Their Predisposing Factors (PAREZ)

Urinary Retention

Slovakia
Comenius University

Completed

Evaluation of Duloxetine and Innovative Pelvic Floor Muscle Training in Women With Stress Urinary Incontinence (DULOXING)

Stress Urinary Incontinence in Women

Slovakia
Comenius University

Recruiting

Stress-Reducing Intervention in Patients With Colorectal and Breast Cancer (SRI-BrCa_CRC)

Breast Cancer | Colon Cancer

Slovakia
Comenius University

Recruiting

Monitoring of Incidence of Mental Discomfort in Pregnant Women During the Serious COVID-19 Pandemic Conditions (COTEPS)

Pregnant Woman

Slovakia
Comenius University

Active, not recruiting

COld Exposure With Controlled BReathing And Meditation in Patients With Multiple Sclerosis (COBRAMS) (COBRAMS)

Multiple Sclerosis

Slovakia
Comenius University

Completed

Effect of Tai Chi on Balance, Mood, Cognition, and Quality of Life in Patients With Multiple Sclerosis (TaiChi-SM)

Multiple Sclerosis

Slovakia
Comenius University

Active, not recruiting

Assessment of Autonomic Nervous Regulation During Postnatal Period in Newborns

Infant, Newborn

Slovakia
Comenius University

Recruiting

Stress-reducing Intervention in Urothelial Carcinoma

Bladder Cancer

Slovakia
Comenius University

Active, not recruiting

Sexual Dysfunction and Anorexia Nervosa (SD&MA)

Anorexia Nervosa

Slovakia
Comenius University

Completed

Physical Exercise and Dairy Probiotics in Childhood Cancer Survivors (Exerbioall)

Acute Lymphoblastic Leukemia, Pediatric

Slovakia
Comenius University

Completed

Evaluation of Silodosin and Pelvic Floor Muscle Training in Men With Benign Prostatic Hyperplasia and Overactive Bladder (SILODOSING)

Overactive Bladder | Benign Prostatic Hyperplasia (BPH)

Slovakia
Comenius University

Enrolling by invitation

Influence of General Anesthesia on the Dynamic Changes in Brain Damage Markers During and After Craniosynostosis Operations in Infancy (TAnBrainDam)

Anesthesia | Craniosynostosis

Slovakia
Comenius University

Completed

Prevalence and Risk Factors for Serious Birth Concerns in Unselected Population of Mothers (RiskfSBC)

Serious Concerns

Slovakia
Comenius University

Unknown

Balance Disorders Related to Pregnancy (PRST)

Pregnancy Related | Fall | Balance, Postural

Slovakia
CoMentis
Alpharmagen, Inc.

Suspended

Safety, Tolerability, and Pharmacokinetics of APN1125 in Subjects With Schizophrenia

Schizophrenia

United States
Conventus Orthopaedics, Inc.

Terminated

Post-Approval Prospective Study - Conventus CAGE™ PH for Use in Proximal Humerus Fracture Fixation

Humeral Fractures, Proximal

United States
Conventus Orthopaedics, Inc.

Terminated

Single Center Post Approval Proximal Humerus Fixation With the Conventus Cage PH™ Device

Proximal Humeral Fracture

United States
CoMentis
Alpharmagen, Inc.

Completed

Safety, Tolerability, and Pharmacokinetics of Single Doses of APN1125 in Healthy Normal Subjects

Schizophrenia

United States
Comenius University
GYN-FIV

Active, not recruiting

Effect of COVID-19 on Platelet Mitochondrial Bioenergetic, Antioxidants and Oxidative Stress in Infertile Men. (COVInfertility)

COVID-19 | Infertility, Male

Slovakia
Cogent Biosciences, Inc.

Recruiting

(Peak) A Phase 3 Randomized Trial of CGT9486+Sunitinib vs. Sunitinib in Subjects With Gastrointestinal Stromal Tumors

Metastatic Cancer | Advanced Gastrointestinal Stromal Tumors

United States, Korea, Republic of, Spain, United Kingdom, Australia, France, Italy, Netherlands, Taiwan, Germany, Denmark, Hong Kong, Canada, Sweden, Norway, Mexico, Czechia, Argentina, Hungary, Brazil, Chile, Poland
Cogent Biosciences, Inc.

Terminated

Study of ACTR T Cell Product in Combination With Trastuzumab in Subjects With HER2-Positive Advanced Solid Tumor Cancers

Solid Tumor | HER-2 Protein Overexpression

United States
Comenius University
NWN & Drink HRW

Completed

Effect of Molecular Hydrogen in Patients With NAFLD (EMoHyNAFLD)

Non-Alcoholic Fatty Liver Disease

Slovakia
Cogent Biosciences, Inc.

Recruiting

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

Advanced Systemic Mastocytosis (AdvSM) | SM With an Associated Hematologic Neoplasm (SM-AHN) | Mast Cell Leukemia (MCL) | Aggressive Systemic Mastocytosis (ASM)

United States, Norway, Spain, Australia, Switzerland, Germany, Belgium, Netherlands, Canada, France, United Kingdom, Austria, Italy
Centus Biotherapeutics Limited

Completed

Evaluation of FKB238 and Avastin in Patients With Advanced/Recurrent Non-squamous Non-small Cell Lung Cancer (AVANA)

Carcinoma, Non-Small-Cell Lung

United States, Belarus, Bosnia and Herzegovina, Bulgaria, Croatia, Georgia, Germany, Greece, Hungary, Italy, Japan, Korea, Republic of, Peru, Philippines, Poland, Romania, Russian Federation, Serbia, Spain, Taiwan, Thailand, Turkey, Ukrain... and more
Cogent Biosciences, Inc.

Recruiting

(Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis

Mastocytosis | Mastocytosis, Systemic | SSM | Mastocytosis, Indolent

United States, Italy, Canada, Australia, Spain, Switzerland, Norway, United Kingdom, Belgium, Poland, Netherlands, Germany, France, Czechia, Greece, Ireland
Cogent Biosciences, Inc.

Terminated

Long-Term Follow-Up Study of Subjects Treated With ACTR T Cell Product

Multiple Myeloma | Solid Tumor | HER-2 Protein Overexpression | B Cell Lymphomas

United States
Cogent Biosciences, Inc.

Terminated

Study of ACTR707 in Combination With Rituximab in Subjects With Relapsed or Refractory B Cell Lymphoma

Lymphoma

United States
Cogent Biosciences, Inc.

Completed

Study of ACTR087 in Subjects With Relapsed or Refractory B-cell Lymphoma

Lymphoma

United States
University Hospital Bratislava
Comenius University

Completed

Acellular Dermal Matrix in Breast Reconstruction (Adermbrerec)

Breast Cancer

Slovakia
University Hospital Bratislava
Comenius University

Completed

Reduction Mammaplasty and Improved Quality of Life (MammaRed)

Quality of Life | Signs and Symptoms | Macromastia

Slovakia
Radboud University Medical Center
CoMentis

Completed

Anti-inflammatory Effects of GTS-21 After LPS

Sepsis | Endotoxemia | Vagal Activity

Netherlands
Comenius University
University Hospital, Martin

Active, not recruiting

Mucosal Flap Reinforced Colorectal Anastomosis and Trans-Anal Vacuum Drainage: A Feasibility Study (Endodrain)

Rectal Cancer

Slovakia
Protina Pharmazeutische GmbH
Comenius University

Completed

Magnesium Supplementation in Stress Conditions

Stress Physiology

Slovakia
CoMentis
Juvenile Diabetes Research Foundation

Completed

Topical Ocular Mecamylamine in Diabetic Macular Edema (DME)

Diabetic Macular Edema

United States
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Study of Safety and Efficacy of Letrozole Monotherapy as Second-line Endocrine Therapy in Postmenopausal Patients With Advanced Breast Cancer Who Received Previous Anti-estrogen Treatment

Postmenopausal Women With Advanced Breast Cancer

Japan
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Extension Study of 1.0mg Dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer

Postmenopausal Women With Advanced Breast Cancer

Japan
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Study of High-dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer

Postmenopausal Women With Advanced Breast Cancer

Japan
Cogent Biosciences, Inc.
Plexxikon

Completed

CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors

Gastrointestinal Stromal Tumors

United States
Slovak Academy of Sciences
Comenius University

Active, not recruiting

Exercise in Testicular Germ Cell Cancer Survivors (ExCell)

Testicular Germ Cell Tumor

Slovakia
Comenius University
Pavol Jozef Safarik University

Active, not recruiting

Measurement of Intravaginal and Intra-abdominal Pressure and Pad Test During Sports Activities (SPORTVAGPRES) (SPORTVAGPRES)

Stress Urinary Incontinence | Athletes

Slovakia
Slovak Academy of Sciences
Comenius University

Completed

Multiple Sclerosis: The Role of Mitochondrial Dysfunction in IR Resistance (MS-MIDY)

Multiple Sclerosis | Mitochondrial Alteration

Slovakia

Clinical Trials Sponsored by Cogentus Pharmaceuticals

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