Clinical Trials Sponsored by Conatus Pharmaceuticals

Total 20896 results

Conatus Pharmaceuticals Inc.

Completed

A Trial of IDN-6556 in Post Orthotopic Liver Transplant for Chronic HCV (POLT-HCV-SVR)

Liver Cirrhosis | Hepatic Fibrosis | Liver Fibrosis | Hepatic Cirrhosis

United States
Conatus Pharmaceuticals Inc.

Unknown

Emricasan, a Caspase Inhibitor, for Treatment of Subjects With Decompensated NASH Cirrhosis (ENCORE-LF)

Decompensated Cirrhosis

United States
Conatus Pharmaceuticals Inc.

Completed

A Study of IDN-6556 in Subjects With NAFLD and Raised Transaminases (NAFLD)

Non-alcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

United States
Conatus Pharmaceuticals Inc.

Completed

PK and PD Study of IDN-6556 in Subjects With Severe Renal Impairment and Matched Healthy Volunteers

Kidney Diseases | Renal Insufficiency | Renal Impairment | Kidney Disease

United States
Conatus Pharmaceuticals Inc.

Completed

Emricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis (ENCORE-NF)

Liver Diseases | Fibrosis | Non-alcoholic Steatohepatitis

United States, Spain, Germany
Conatus Pharmaceuticals Inc.

Completed

A Study of IDN-6556 in Subjects With Liver Cirrhosis (LC)

Liver Cirrhosis | Hepatic Cirrhosis

United States
Conatus Pharmaceuticals Inc.

Completed

PK and PD Study of IDN-6556 in Subjects With Hepatic Impairment and Matched Healthy Volunteers

Liver Diseases | Digestive System Diseases | Hepatic Impairment

United States
Conatus Pharmaceuticals Inc.

Terminated

Standard of Care (SOC) With or Without CTS-1027 in Hepatitis C (HCV) Null-Responders

Hepatitis C

United States
Conatus Pharmaceuticals Inc.

Completed

CTS-1027 in Interferon-Naive Hepatitis C Patients

Hepatitis C

United States, Puerto Rico
Conatus Pharmaceuticals Inc.

Terminated

Post-Treatment Follow-up Study for Liver Disease Subjects With or Without Cirrhosis After Receiving Emricasan or Placebo

Liver Diseases | Liver Cirrhosis | Liver Fibrosis | NASH Fibrosis | Decompensated Non-Alcoholic Steatohepatitis Cirrhosis | Orthotopic Liver Transplantation

United States
Conatus Pharmaceuticals Inc.

Completed

A Study of IDN-6556 in Cirrhotic Subjects With Portal Hypertension (PH)

Liver Cirrhosis | Portal Hypertension | Hepatic Cirrhosis

United States
Conatus Pharmaceuticals Inc.

Terminated

Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF

Liver Cirrhosis | Acute on Chronic Hepatic Failure | Acute Liver Failure | Acute Alcoholic Hepatitis

United States, United Kingdom
Conatus Pharmaceuticals Inc.

Completed

Study of CTS-1027 in Combination With Pegylated Interferon and Ribavirin in Hepatitis C Virus (HCV) Null-Responders (CTS-1027-04)

Hepatitis C

United States, Puerto Rico
Conatus Pharmaceuticals Inc.
Idun Pharmaceuticals

Completed

A Caspase Inhibitor in Chronic Hepatitis C (HCV) Patients

Hepatitis C, Chronic

United States
Conatus Pharmaceuticals Inc.
Idun Pharmaceuticals

Completed

Safety and Efficacy Study of a Caspase Inhibitor in Patients Undergoing Liver Transplantation

Liver Transplantation | Hepatitis | Carcinoma, Hepatocellular | Cholestasis

United States, Germany
Meridian Bioscience, Inc.
Conatus Pharmaceuticals

Completed

Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14

Cirrhosis | Portal Hypertension | NASH - Nonalcoholic Steatohepatitis

France
Meridian Bioscience, Inc.
Conatus Pharmaceuticals

Terminated

Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-17

Decompensated Cirrhosis

United States
University of Alberta
Conatus Pharmaceuticals Inc.

Completed

Caspase Inhibition in Islet Transplantation

Diabetes

Canada
Conatus Pharmaceuticals Inc.
FGK Clinical Research GmbH

Completed

Study of CTS-1027 in Hepatitis C Patients

Chronic Hepatitis C Virus Infection

United States
Conatus Pharmaceuticals Inc.
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Terminated

Study of IDN-6556 in Patients With Severe Alcoholic Hepatitis and Contraindications to Steroid Therapy (AH)

Alcoholic Hepatitis

United States
Renatus, Antonio Renatus, Dent., M.Sc

Completed

Evaluation of a New Self-reported Tool for Periodontitis Screening

Periodontitis and Treatment Need
Corautus Genetics

Unknown

To Find the Best Dose of pVGI.1(VEGF2) to Benefit Angina Patients When Given With an Experimental Injection Catheter

Angina Pectoris

United States
St. Renatus, LLC
Rho, Inc.; Ground Zero Pharmaceuticals

Completed

Safety and Effectiveness of Kovacaine Nasal Spray for Dental Anesthesia

Dental Anesthesia Efficacy

United States
St. Renatus, LLC
Rho, Inc.; Ground Zero Pharmaceuticals

Completed

Dose-Escalation Safety and Pharmacokinetic Study of K305

Anesthesia

United States
Sonitus Medical Inc

Unknown

Evaluation of Benefit for Treatment of Single Sided Deafness (SSD) Between Two Bone Conduction Prosthetic Devices; Osseointegrated Implant Versus Maxilla Anchored Removable Oral Appliance ("SoundBite")

Single Sided Deafness

United States
Sonitus Medical Inc

Completed

Bone Conduction Auditory Performance Via the Tooth for Single-Sided Deafness

Unilateral Hearing Loss

United States
Sonitus Medical Inc

Unknown

SoundBite Hearing System Long Term Multi Site Patient Use Study

Conductive Hearing Loss | Single Sided Deafness

United States
St. Renatus, LLC

Completed

Comparison of Anesthetic Efficacy of Bilateral and Unillateral Application of Kovacaine Mist in Healthy Volunteers

Anesthesia

United States
Sonitus Medical Inc

Completed

Long Term Safety of the Sonitus SoundBite System

Hearing Loss | Unilateral Hearing Loss | Total Unilateral Deafness

United States
Sonitus Medical Inc

Unknown

SoundBite Hearing System 24 Month Multi Site Patient Use Study

Conductive Hearing Loss | Single Sided Deafness

United States
Centus Biotherapeutics Limited

Completed

Evaluation of FKB238 and Avastin in Patients With Advanced/Recurrent Non-squamous Non-small Cell Lung Cancer (AVANA)

Carcinoma, Non-Small-Cell Lung

United States, Belarus, Bosnia and Herzegovina, Bulgaria, Croatia, Georgia, Germany, Greece, Hungary, Italy, Japan, Korea, Republic of, Peru, Philippines, Poland, Romania, Russian Federation, Serbia, Spain, Taiwan, Thailand, Turkey, Ukrain... and more
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Study of Safety and Efficacy of Letrozole Monotherapy as Second-line Endocrine Therapy in Postmenopausal Patients With Advanced Breast Cancer Who Received Previous Anti-estrogen Treatment

Postmenopausal Women With Advanced Breast Cancer

Japan
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Extension Study of 1.0mg Dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer

Postmenopausal Women With Advanced Breast Cancer

Japan
Novartis Pharmaceuticals
Chugai Pharmaceutical

Completed

Study of High-dose Letrozole Therapy in Postmenopausal Patients With Breast Cancer

Postmenopausal Women With Advanced Breast Cancer

Japan
Novartis Pharmaceuticals
Pharmaceutical Research Associates

Withdrawn

Pharmacokinetics Study of TNO155 in Participants With Mild, Moderate, or Severe Renal Impairment Compared to Matched Healthy Participants

Renal Impairment
Novartis Pharmaceuticals
Pharmaceutical Research Associates

Withdrawn

Pharmacokinetics of TNO155 in Participants With Mild, Moderate, or Severe Hepatic Impairment Compared to Matched Healthy Participants

Hepatic Impairment
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip (FACT OA2)

Osteoarthritis, Knee | Osteoarthritis, Hip

United States
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

A Study of EDP-514 in Patients With Chronic Hepatitis B Virus Infection Who Are Not Currently on Treatment

Chronic HBV Infection

Hong Kong, Taiwan
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Terminated

Evaluate the Efficacy and Safety of Fasinumab in Patients With Moderate-to-Severe Chronic Low Back Pain and Osteoarthritis of the Hip or Knee (FACT CLBP 1)

Osteoarthritis | Chronic Low Back Pain

United States
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

Drug-Drug Interaction Study Between EDP-938, Itraconazole, Rifampin, and Quinidine in Healthy Subjects

RSV Infection

United States
Melior Pharmaceuticals
Bukwang Pharmaceutical, Co., Ltd.

Completed

Adult Subjects With Uncontrolled Type 2 Diabetes

Type 2 Diabetes

United States
Tibotec Pharmaceuticals, Ireland
Tibotec Pharmaceutical Limited

Completed

A Safety Study to Evaluate the Antiviral Activity of Darunavir in Combination With Ritonavir in HIV 1 Infected Children

Human Immunodeficiency Virus 1

South Africa, Argentina, Brazil, India, Kenya
Vertex Pharmaceuticals Incorporated
Tibotec Pharmaceutical Limited

Completed

A Study to Examine the Effects of Telaprevir on the Pharmacokinetics of Cyclosporine and Tacrolimus in Healthy Adults

Hepatitis C

United States
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip (FACT LTS & OA)

Osteoarthritis of the Knee or Hip

United States, Bulgaria, Chile, Colombia, Denmark, Estonia, Germany, Hong Kong, Hungary, Italy, Lithuania, Mexico, Peru, Poland, Romania, Russian Federation, South Africa, Spain, Sweden, Ukraine, United Kingdom
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

Study to Evaluate the Effects of Fasinumab on Peripheral Nerve Function in Patients With Pain Due to Osteoarthritis of the Hip or Knee

Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Poland, United Kingdom
Regeneron Pharmaceuticals
Teva Pharmaceutical Industries, Ltd.

Completed

A Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Naproxen for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip (FACT OA1)

Osteoarthritis, Knee | Osteoarthritis, Hip

United States, Poland, Hungary, Spain, Germany, United Kingdom, Denmark, Lithuania, Romania, Russian Federation, South Africa, Ukraine
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

A Study of EDP-514 in Healthy Subjects (Part 1) and Patients With Chronic Hepatitis B Virus Infection (Part 2)

Chronic HBV Infection

United States, Canada
Melior Pharmaceuticals
Bukwang Pharmaceutical, Co., Ltd.

Unknown

An Add-on Study of MLR-1023 in Adults With Uncontrolled Type 2 Diabetes on Metformin Therapy

Type 2 Diabetes Mellitus

United States
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

A Study of EDP-938 in Healthy Subjects

RSV Infection

United States
Enanta Pharmaceuticals, Inc
Pharmaceutical Research Associates

Completed

A Study of EDP 305 in Healthy Subjects and Subjects With Presumptive NAFLD

Presumptive NAFLD

United States

Clinical Trials Sponsored by Conatus Pharmaceuticals

Sponsors and Collaborators

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CROs in Ecuador

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