Clinical Trials Sponsored by Desmond Tutu HIV Centre

Total 27 results

Desmond Tutu HIV Centre

Unknown

A Study to Evaluate the Acceptability and Preference for Contraceptive Options as Proxy for HIV Prevention Methods (UChoose)

HIV

South Africa
University of Cape Town
Desmond Tutu HIV Centre; Wits Reproductive Health and HIV Institute

Terminated

Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected Volunteers (Darifi)

HIV Infections

South Africa
Helen Reynolds
Desmond Tutu HIV Centre; Infectious Disease Institute, Kampala, Uganda

Active, not recruiting

Drug Interactions Between Dolutegravir and Escalating Doses of Rifampicin (DoRIS)

Tuberculosis | Hiv

Uganda, South Africa
University of Pennsylvania
Bill and Melinda Gates Foundation; Desmond Tutu HIV Foundation

Completed

Effect of U=U Messaging on HIV in South Africa (U=U)

HIV/AIDS

South Africa
University of California, Los Angeles
University of Cape Town; Desmond Tutu HIV Foundation

Completed

Evaluation of Pre-exposure Prophylaxis Cascade in Pregnant and Breastfeeding Women in Cape Town (Formative Study) (PrEP-PP)

Hiv

South Africa
Desmond Tutu HIV Centre
Merck Sharp & Dohme LLC; European and Developing Countries Clinical Trials...

Unknown

Preparing for Adolescent HIV Vaccine Trials in South Africa: (CATSA)

HIV Infections | HIV Infection

South Africa
University of California, Los Angeles
Gilead Sciences; University of Cape Town; Desmond Tutu HIV Foundation

Completed

PK of TAF and TDF for PrEP in Pregnant and Postpartum Women (PrEP-PP PK)

Hiv

South Africa
Desmond Tutu TB Centre
University of Stellenbosch; UNITAID; Chiang Mai University

Recruiting

Pharmacokinetics and Safety of DolutegravIr in Neonate (PETITE-DTG)

Hiv

South Africa
Desmond Tutu HIV Centre
National Institute of Mental Health (NIMH); Bill and Melinda Gates Foundation; University of Washington

Unknown

3Ps for Prevention Study (Perception, Partners, Pills) (3P)

Adherence

South Africa
Massachusetts General Hospital
Bill and Melinda Gates Foundation; Mbarara University of Science and Technology and other collaborators

Completed

Examining HIV Treatment Adherence During Early Disease (META)

HIV | Medication Adherence

South Africa, Uganda
Desmond Tutu HIV Foundation
National Institutes of Health (NIH); University of Cape Town; Zeteo Tech Incorporated

Completed

Bioaerosol Sampling in Suspected Pulmonary Tuberculosis

Pulmonary Tuberculosis Confirmation by Sputum Microscopy With or Without Culture

South Africa
Desmond Tutu HIV Foundation
Karolinska Institutet; University of North Carolina, Chapel Hill; ViiV Healthcare and other collaborators

Completed

Bidirectional, Upbeat Communication and Differentiated, Distanced Care for Young People (BUDDY)

HIV Infections | Covid19 | Health Care Utilization | Gender-based Violence

South Africa
Desmond Tutu HIV Foundation
National Institute of Mental Health (NIMH); University of Pennsylvania; National...

Recruiting

Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging

HIV Infections | Treatment Adherence | Men

South Africa
Boston University
National Institute of Mental Health (NIMH); Massachusetts General Hospital; New... and other collaborators

Recruiting

Supporting Sustained HIV Treatment Adherence After Initiation (SUSTAIN)

HIV Infections | Adherence, Medication

South Africa
Brown University
Rhode Island Hospital; University of Cape Town; Medical Research Council, South... and other collaborators

Active, not recruiting

Our Family Our Future: A Resilience-oriented Family Intervention to Prevent Adolescent HIV/STI Infection and Depression in South Africa

Depression | Sexually Transmitted Diseases | Human Immunodeficiency Virus

South Africa
University of Illinois at Chicago
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women: IMARA SA (IMARA-SA pilot)

Hiv | Sexually Transmitted Infection

South Africa
Foundation for Professional Development (Pty) Ltd
National Institute of Mental Health (NIMH); National Institutes of Health (NIH) and other collaborators

Active, not recruiting

The Community PrEP Study to Assess the Acceptance of PrEP Delivered Through CBCT Platforms

PrEP | HIV Prevention | Cost-effectiveness | Adolescence

South Africa
New York State Psychiatric Institute
National Institute of Allergy and Infectious Diseases (NIAID); Columbia University and other collaborators

Recruiting

Effectiveness and Cost-Effectiveness of Depression Treatment for Individuals With TB in South Africa

Depression | Tuberculosis

South Africa
Desmond Tutu HIV Foundation
Amsterdam Institute for Global Health and Development; University of Cape Town and other collaborators

Completed

Transmission of Coronavirus Disease 2019 (COVID19) in Crowded Environments (TRACE)

Covid19 | Sars-CoV-2 Infection

South Africa
Boston Medical Center
Boston University; National Institute of Allergy and Infectious Diseases (NIAID) and other collaborators

Enrolling by invitation

Transmission of Tuberculosis Among Illicit Drug Use Linkages (TOTAL)

Tuberculosis | Illicit Drug Use

South Africa
University of Liverpool
University of Cape Town; Desmond Tutu HIV Foundation; Infectious Diseases Institute... and other collaborators

Completed

Pharmacokinetics of Atazanavir in Special Populations (VirTUAL WP5)

HIV/AIDS | Tuberculosis

Uganda, South Africa
University of Washington
Harvard Medical School (HMS and HSDM); National Institute of Mental Health... and other collaborators

Completed

The Prevention Options for Women Evaluation Research (POWER) Cohort

HIV/AIDS

Kenya, South Africa
New York State Psychiatric Institute
University of Colorado, Denver; National Institute of Allergy and Infectious... and other collaborators

Completed

Use of Antiretroviral (ARV) Drug Levels in Dried Blood Spots (DBS) to Assess and Manage ART Adherence in South Africa (ADD-ART)

Therapeutic Adherence and Compliance

United States, South Africa
University of Cape Town
London School of Hygiene and Tropical Medicine; UMC Utrecht; Institut Pasteur; Institut... and other collaborators

Recruiting

Comparing a Novel Point-of-care Cytokine Biomarker Lateral Flow Test With Nucleic Acid Amplification Tests for Detection of Sexually Transmitted Infections and Bacterial Vaginosis (GIFT)

STI

Madagascar, South Africa, Zimbabwe
MRC/UVRI and LSHTM Uganda Research Unit
London School of Hygiene and Tropical Medicine; Assistance Publique - Hôpitaux... and other collaborators

Not yet recruiting

Implementing Oral (Event-driven and Daily) and Long-acting Pre-Exposure Prophylaxis in Mobile Men in Sub-Saharan Africa (MOBILEMEN)

HIV
Serum Institute of India Pvt. Ltd.
University of Stellenbosch; South African Tuberculosis Vaccine Initiative; Vakzine... and other collaborators

Completed

Study to Evaluate the Safety and Immunogenicity of VPM1002 in Comparison With BCG in HIV-exposed/-Unexposed Newborn Infants in South Africa

Tuberculosis

South Africa
HIV Prevention Trials Network
London School of Hygiene and Tropical Medicine; National Institute on Drug... and other collaborators

Completed

Population Effects of Antiretroviral Therapy to Reduce HIV Transmission (PopART) (PopART)

HIV

Zambia, South Africa

Clinical Trials Sponsored by Desmond Tutu HIV Centre

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