Clinical Trials Sponsored by Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Total 48 results

Deutsches Herzzentrum Muenchen
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Prospective, Randomized Trial of Ticagrelor Versus Prasugrel in Patients With Acute Coronary Syndrome (ISAR-REACT 5)

Acute Coronary Syndrome (ACS)

Germany, Italy
Goethe University
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Validation of CMR Against Invasive Haemodynamics in Patients With HFpEF (DECIPHER-HFpEF)

Heart Failure With Normal Ejection Fraction

Germany
LMU Klinikum
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Vascular Healing After BVS-implantation

Coronary Heart Disease

Germany
University of Luebeck
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Ultrasound Evaluation of the IVC in Addition to Clinical Assessment to Guide Decongestion in ADHF (CAVA-ADHF)

Heart Failure

Germany
Universitätsklinikum Hamburg-Eppendorf
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK); Deutsche Herzstiftung...

Active, not recruiting

Randomized Trial of TAVI vs. SAVR in Patients With Severe Aortic Valve Stenosis at Low to Intermediate Risk of Mortality (DEDICATE)

Aortic Valve Stenosis

Germany
University Medicine Greifswald
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Recruiting

Cardiovascular Effects of Preferred Home-based Exercise Training in Systolic Heart Failure (HOMEX-HF-P)

Chronic Heart Failure

Germany
University Medicine Greifswald
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Efficacy of a Brief Intervention on Reduction of Systolic Blood Pressure

Cardiovascular Risk Factor | Blood Pressure, High

Germany
University Medicine Greifswald
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Closing the Gap Between Self-reported and Accelerometer-based Physical Activity (GAP)

Physical Activity

Germany
University of Göttingen
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Feasability of Collaborative Care in the Secondary Prevention of Coronary Heart Disease

Coronary Heart Disease

Germany
German Heart Institute
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Unknown

Risk Stratification in Children and Adolescents With Primary Cardiomyopathy (RIKADA)

Dilated Cardiomyopathy | Hypertrophic Cardiomyopathy | Arrhythmogenic Right Ventricular Cardiomyopathy | Restrictive Cardiomyopathy | Left Ventricular Noncompaction | Primary Cardiomyopathy

Germany
Universitätsklinikum Hamburg-Eppendorf
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Recruiting

The PAtients pResenTing With COngenital HeaRt DIseAse Register (ARTORIA-R) (ARTORIA-R)

Heart Failure | Ventricular Dysfunction | Congenital Heart Disease | Arrythmia | Transplant; Complication, Failure

Germany
University Medicine Greifswald
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Physical Activity Level During Pregnancy (Fit4Two)

Physical Activity | Well-being

Germany
University Hospital Heidelberg
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Catheter Ablation for Atrial Fibrillation in Preserved Ejection Fraction (AFFECT)

Atrial Fibrillation

Germany
University of Göttingen
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

CMR Exercise Stress Testing in HFpEF (HFpEF-Stress)

Diastolic Heart Failure

Germany
University of Göttingen
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Enhancement of Physical Activity in Elderly Patients With Diastolic Heart Failure by a Motivational Intervention (Ex-DHFadd-on)

Diastolic Heart Failure
German Heart Institute
Deutsche Stiftung für Herzforschung; Deutsches Zentrum für Herz-Kreislauf-Forschung...

Recruiting

Microvascular Cardiac Allograft Vasculopathy Trial (mCAV)

Cardiac Allograft Vasculopathy

Germany
Charite University, Berlin, Germany
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Recruiting

Sex-differential Host-microbiome CVD Risk - A Longitudinal Cohort Approach (XCVD)

Cardiovascular Risk Factors | Gut Microbiome | Transgender | Immune System

Germany
University Hospital Schleswig-Holstein
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Immediate Unselected Coronary Angiography Versus Delayed Triage in Survivors of Out-of-hospital Cardiac Arrest Without ST-segment Elevation (TOMAHAWK)

Out-of-hospital Cardiac Arrest

Germany
Charite University, Berlin, Germany
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Recruiting

Randomized Trial to Examine a Differential Therapeutic Response in Symptomatic Patients With Non-obstructive Coronary Artery Disease (EXAMINE-CAD)

Coronary Artery Disease | Microvascular Angina | Vasospastic Angina | Coronary Microvascular Dysfunction | Vasospasm, Coronary | Prinzmetal Angina

Germany, Switzerland
Charite University, Berlin, Germany
Bayer; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Terminated

Effect of Anticoagulation Therapy on Clinical Outcomes in COVID-19 (COVID-PREVENT)

COVID-19

Germany
LMU Klinikum
Medtronic Bakken Research Center; Deutsches Zentrum für Herz-Kreislauf-Forschung...

Completed

Implantable Cardiac Monitors in High-Risk Post-Infarction Patients With Cardiac Autonomic Dysfunction (SMART-MI)

Myocardial Infarction | Autonomic Nervous System Diseases

Germany, Austria
Universitätsklinikum Hamburg-Eppendorf
Abbott Medical Devices; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

SORT - AF Supervised Obesity Reduction Trial for AF Ablation Patients (SORT-AF)

Obesity | Atrial Fibrillation | Sleep Apnea

Germany
University of Göttingen
University Medical Center Goettingen; Deutsches Zentrum für Herz-Kreislauf-Forschung...

Active, not recruiting

TransitionCHF Systolic Dysfunction to Congestive Heart Failure Cohort Study (TransitionCHF)

Systolic Dysfunction, Transition, Heart Failure, Biobank

Germany
Universitätsklinikum Hamburg-Eppendorf
Charite University, Berlin, Germany; Deutsches Zentrum für Herz-Kreislauf-Forschung...

Recruiting

Intravenous Iron in Patients With Systolic Heart Failure and Iron Deficiency to Improve Morbidity & Mortality (FAIR-HF2)

Iron Deficiency | Systolic Heart Failure

Germany, Hungary, Italy, Poland, Portugal, Serbia, Slovenia, Spain
Atrial Fibrillation Network
Bristol-Myers Squibb; Pfizer; Deutsches Zentrum für Herz-Kreislauf-Forschung...

Completed

Apixaban During Atrial Fibrillation Catheter Ablation: Comparison to Vitamin K Antagonist Therapy (AXAFA)

Atrial Fibrillation

United States, Austria, Belgium, Denmark, Germany, Italy, Netherlands, Spain, United Kingdom
University of Luebeck
European Commission; Deutsche Stiftung für Herzforschung; Deutsches Zentrum für... and other collaborators

Completed

Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock (CULPRIT-SHOCK)

Complications | Acute Myocardial Infarction | Cardiogenic Shock

Germany
Prof. Dr. med. Ingo Eitel
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Recruiting

Cardiac Magnetic Resonance Guidance of Implantable Cardioverter Defibrillator Implantation in Non-ischemic Dilated Cardiomyopathy (CMR-ICD)

Non-ischemic Dilated Cardiomyopathy

Germany
Medical University Innsbruck
Ludwig-Maximilians - University of Munich; Deutsches Zentrum für Herz-Kreislauf-Forschung...

Completed

Stopping ACE-inhibitors in COVID-19 (ACEI-COVID)

COVID-19 | SARS-CoV-2

Germany, Austria
University of Edinburgh
British Heart Foundation; Netherlands Heart Foundation; Deutsches Zentrum für...

Recruiting

Quantitative-imaging in Cardiac Transthyretin Amyloidosis (I-CARE)

ATTR-CM

Netherlands
Ludwig-Maximilians - University of Munich
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK); Gesundheitsreferat (GSR)...

Active, not recruiting

Telemedicine in Outpatient Covid-19 Patients (COVID-SMART)

Covid-19 | Cardiovascular Risk Factor

Germany
Philipps University Marburg Medical Center
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK); Competence Network Heart...

Completed

Inflammatory/Familial Dilated Cardiomyopathy: Is There a Link to Autoimmune Diseases? TP9a (Ikarius)

Non Ischemic Cardiomyopathy
Charite University, Berlin, Germany
German Center for Neurodegenerative Diseases (DZNE); Deutsches Zentrum für...

Completed

PRediction of Acute Coronary Syndrome in Acute Ischemic StrokE (PRAISE)

Acute Coronary Syndrome | Stroke, Ischemic

Germany
University Medical Center Goettingen
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK); University Medical Center... and other collaborators

Recruiting

Safety and Efficacy of Induced Pluripotent Stem Cell-derived Engineered Human Myocardium as Biological Ventricular Assist Tissue in Terminal Heart Failure (BioVAT-HF)

Heart Failure

Germany
German Heart Institute
University Medicine Greifswald; Helmholtz Zentrum München; University of Göttingen and other collaborators

Active, not recruiting

Early Versus Emergency Left Ventricular Assist Device Implantation in Patients Awaiting Cardiac Transplantation

End Stage Heart Disease

Germany
Charite University, Berlin, Germany
Stiftung Institut fuer Herzinfarktforschung; Deutsches Zentrum für Herz-Kreislauf-Forschung... and other collaborators

Recruiting

Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical Therapy (CLOSURE-AF)

Atrial Fibrillation

Germany
Atrial Fibrillation Network
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company; Deutsches Zentrum für...

Terminated

Non-vitamin K Antagonist Oral Anticoagulants in Patients With Atrial High Rate Episodes (NOAH)

Atrial High Rate Episodes

Austria, Belgium, Bulgaria, Czechia, France, Germany, Greece, Hungary, Italy, Netherlands, Poland, Portugal, Romania, Spain, Sweden, Ukraine, United Kingdom, Denmark
Charite University, Berlin, Germany
Boston Scientific Corporation; Deutsches Zentrum für Herz-Kreislauf-Forschung... and other collaborators

Recruiting

CAtheter-Based Ablation of Atrial Fibrillation Compared to Conventional Treatment in Patients With Heart Failure With Preserved Ejection Fraction (CABA-HFPEF)

Atrial Fibrillation | Heart Failure With Preserved Ejection Fraction | Heart Failure With Mildly Reduced Ejection Fraction

Germany
Deutsches Herzzentrum Muenchen
German Federal Ministry of Education and Research; Technical University of... and other collaborators

Completed

Intracoronary Stenting and Antithrombotic Regimen: Lesion Platelet Adhesion as Selective Target of Endovenous Revacept (ISAR-PLASTER)

Stable Coronary Artery Disease

Germany
Atrial Fibrillation Network
Sanofi; Abbott; Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK); Deutsche... and other collaborators

Completed

Early Treatment of Atrial Fibrillation for Stroke Prevention Trial (EAST)

Stroke | Atrial Fibrillation

Belgium, Czechia, Denmark, France, Germany, Italy, Netherlands, Poland, Spain, Switzerland, United Kingdom
University Hospital Heidelberg
The German Heart Foundation; Apple Inc.; Deutsches Zentrum für Herz-Kreislauf-Forschung... and other collaborators

Recruiting

activeDCM - Interventional Clinical Trial of Individualized Activity and Exercise Programs to Improve Outcome in Dilated Cardiomyopathy Guided by Longitudinal Biosensing With Apple Watch (ACTIVE-DCM)

Heart Failure | Cardiomyopathy, Dilated

Germany
LMU Klinikum
University Medicine Greifswald; Technical University of Munich; Helmholtz Zentrum... and other collaborators

Completed

APixaban vs. PhenpRocoumon in Patients With ACS and AF: APPROACH-ACS-AF (APPROACH)

Coronary Artery Disease | Atrial Fibrillation | Acute Coronary Syndrome

Germany
Charite University, Berlin, Germany
University of Leipzig; University Medicine Greifswald; Technical University of... and other collaborators

Completed

Exercise Training in Patients With Left Ventricular Assist Device (Ex-VAD)

Heart Failure

Germany
German Aortic Valve Registry
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK); German Society for Thoracic... and other collaborators

Recruiting

German Aortic Valve Registry (GARY)

Aortic Valve Stenosis | Aortic Valve Insufficiency

Germany
LMU Klinikum
Charite University, Berlin, Germany; University Hospital, Essen; University Hospital... and other collaborators

Recruiting

Immunosuppressive Treatment in Chronic Virus-Negative Inflammatory Cardiomyopathy (TRINITY)

Inflammatory Cardiomyopathy

Germany
LMU Klinikum
University of Leipzig; Heart Center Leipzig - University Hospital; Deutsches... and other collaborators

Recruiting

TRICuspid Intervention in Heart Failure Trial (TRICI-HF)

Heart Failure Attributable to Severe Tricuspid Regurgitation

Germany
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Active, not recruiting

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Tricuspid Regurgitation | Mild Tricuspid Regurgitation | Moderate Tricuspid Regurgitation

United States, Canada, Germany
Charite University, Berlin, Germany
Ludwig-Maximilians - University of Munich; University Medicine Greifswald; University... and other collaborators

Recruiting

Spironolactone In The Treatment of Heart Failure (SPIRIT-HF)

Heart Failure With Preserved Ejection Fraction | Heart Failure With Mid-range Ejection Fraction

Austria, Germany, Netherlands, France, Serbia
Population Health Research Institute
Canadian Institutes of Health Research (CIHR); University of Leipzig; Heart and... and other collaborators

Completed

Home-Based Screening for Early Detection of Atrial Fibrillation in Primary Care Patients Aged 75 Years and Older (SCREEN-AF)

Hypertension | Atrial Fibrillation

Canada, Germany

Clinical Trials Sponsored by Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

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