Clinical Trials Sponsored by Eastern Cooperative Oncology Group

Total 612 results

Eastern Cooperative Oncology Group

Active, not recruiting

COVID-19 Related Financial Hardship and Distress in Women Who Decline TMIST (EA1151) Participation

Breast Cancer, NOS

United States
Eastern Cooperative Oncology Group

Completed

Double Blind Phase III Trial of Effects of Low Dose 13-Cisretinoic Acid on Prevention of Second Primaries in Stages I-II Head and Neck Cancer

Stage I-II Head and Neck Cancer
Eastern Cooperative Oncology Group

Recruiting

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

Melanoma | Breast Cancer, NOS | CNS Primary Tumor, NOS | Cervical Cancer, NOS | Colorectal Cancer, NOS | Leukemia, NOS | Lymphoma, NOS | Miscellaneous Neoplasm, NOS | Non-Rhabdomyosarcoma Soft Tissue Sarcoma, NOS | Testicular Nonseminomatous Germ Cell Tumor, NOS | Thyroid Cancer, NOS | Bone Cancer, NOS

United States
Eastern Cooperative Oncology Group

Completed

Phase III rhu_GM-CSF + 3 Induction Regimens in Adults With Acute Non-Lymphocytic Leukemia

Adult Patients (Over 55) With Acute Non-Lymphocytic Leukemia
Eastern Cooperative Oncology Group

Terminated

Rituximab and Combination Chemotherapy in Treating Patients With Primary Central Nervous System Lymphoma

Lymphoma

United States
Invitae Corporation
Eastern Cooperative Oncology Group

Terminated

ARTEMIS: Study of Patients With Early Stage Pancreatic Cancer Who Have Undergone Genetic Testing (ARTEMIS)

Pancreatic Cancer | Pancreatic Adenocarcinoma | Resectable Pancreatic Cancer

United States
Eastern Cooperative Oncology Group
Janssen, LP

Recruiting

Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL

T-cell Acute Lymphoblastic Leukemia

United States
ECOG-ACRIN Cancer Research Group

Not yet recruiting

Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

Glioblastoma, IDH-Wildtype
ECOG-ACRIN Cancer Research Group

Recruiting

Testing the Role of FDG-PET/CT to Predict Response to Therapy Prior to Surgery for HER2-positive Breast Cancer, The DIRECT Trial

Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Invasive Breast Carcinoma | HER2-Positive Breast Carcinoma

United States
ECOG-ACRIN Cancer Research Group

Recruiting

Venetoclax and Vincristine Liposomal in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia

Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | B Acute Lymphoblastic Leukemia | Refractory Acute Lymphoblastic Leukemia | T Acute Lymphoblastic Leukemia | Lymphoblasts 5 Percent or More of Bone Marrow Nucleated Cells

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

S9431: Studying Genes and Immune Response in Tumor Samples From Patients With Locally Advanced or Metastatic Melanoma

Melanoma (Skin)
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Terminated

S9624 Ifosfamide in Treating Patients With Meningeal Tumors

Chondrosarcoma | Adult Rhabdomyosarcoma | Adult Fibrosarcoma | Adult Leiomyosarcoma | Adult Malignant Meningioma | Adult Brain Malignant Hemangiopericytoma

United States, Australia, Peru, Puerto Rico
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; Southwest Oncology Group

Completed

Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer

Mucinous Adenocarcinoma of the Rectum | Signet Ring Adenocarcinoma of the Rectum | Stage IIIA Rectal Cancer | Stage IIIB Rectal Cancer | Stage IIIC Rectal Cancer | Mucinous Adenocarcinoma of the Colon | Signet Ring Adenocarcinoma of the Colon | Stage IIIA Colon Cancer | Stage IIIB Colon Cancer | Stage... and other conditions

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

S9811 Hydroxyurea in Treating Patients With Unresectable Benign Meningioma

Adult Meningioma

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Withdrawn

S9715, Chemotherapy and Radiation Therapy in Treating Patients With Advanced Cancer of the Nasopharynx

Head and Neck Cancer
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

S9007, Study of Bone Marrow and Blood Samples From Patients With Leukemia or Other Hematopoietic Cancers

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United States
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; Southwest Oncology Group

Completed

Low, Intermediate, or High Dose Suramin in Treating Patients With Hormone-Refractory Prostate Cancer

Prostate Cancer

United States, South Africa
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Withdrawn

S0408: Capecitabine, Oxaliplatin, and Bevacizumab in Pts Undergoing Surgery for Liver Mets From Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Terminated

S0224, Docetaxel in Treating Patients With Locally Advanced or Metastatic Penile Cancer (TERMINATED)

Penile Cancer

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI); Southwest Oncology Group

Completed

Combination Chemotherapy in Treating Patients With Advanced Head and Neck Cancer

Head and Neck Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

SWOG-9239 Reduction of Immunosuppression Plus Interferon Alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant

Lymphoma | Multiple Myeloma and Plasma Cell Neoplasm

United States
Southwest Oncology Group
National Cancer Institute (NCI); Eastern Cooperative Oncology Group

Completed

SWOG-9430: Surgery in Treating Patients With Metastatic Melanoma

Melanoma (Skin)

United States
Sunnybrook Health Sciences Centre
Eastern Cooperative Oncology Group

Active, not recruiting

Tomosynthesis Mammographic Imaging Screening Trial (TMISTLead-in)

Breast Cancer

Canada
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

Lymphoma | Neurotoxicity | Therapy-related Toxicity

United States, Canada
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Doxorubicin and Gemcitabine in Treating Patients With Locally Recurrent or Metastatic Unresectable Renal Cell Carcinoma

Metastatic Renal Cell Carcinoma | Renal Cell Carcinoma With Sarcomatoid Features

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Interferon Alfa, Isotretinoin, and Paclitaxel in Treating Patients With Recurrent Small Cell Lung Cancer

Lung Cancer

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Terminated

Methotrexate With or Without Cyclophosphamide in Treating Patients With Lymphocytic Leukemia

Leukemia

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Refractory Non-Small Cell Lung Cancer

Lung Cancer

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Cetuximab, Chemotherapy, and Radiation Therapy for Operable Stage III or IV Head and Neck Cancer

Head and Neck Cancer
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Rituximab and Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Non-Hodgkin's Lymphoma

Lymphoma

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Phase II Study of Concurrent C225, Cisplatin and Radiation in Stage IV Squamous Cell Carcinoma of the Head and Neck

Head and Neck Cancer
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Reduced-Intensity Regimen Before Donor Bone Marrow Transplant in Treating Patients With Myelodysplastic Syndromes

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Induction Chemotherapy Followed By Cetuximab and Radiation in HPV-Associated Resectable Stage III/IV Oropharynx Cancer

Head and Neck Cancer | Precancerous Condition

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Atrasentan in Treating Patients With Locally Recurrent or Metastatic Kidney Cancer

Kidney Cancer

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Terminated

Evaluation of Breast Cancer Recurrence Rates Following Surgery in Women With Ductal Carcinoma In Situ

Breast Cancer

United States, South Africa
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Paclitaxel Plus Gemcitabine in Treating Patients With Refractory Metastatic Germ Cell Tumors

Testicular Germ Cell Tumor | Ovarian Cancer

United States, South Africa
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Bevacizumab and Combination Chemotherapy in Treating Patients With Peripheral T-Cell Lymphoma or Natural Killer Cell Neoplasms

Lymphoma

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Methylphenidate in Treating Patients With Melanoma

Fatigue | Unspecified Adult Solid Tumor, Protocol Specific

United States, Puerto Rico, South Africa
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Study of Symptoms Caused by Cancer and Cancer Therapy in Patients With Invasive Breast, Lung, Prostate, or Colorectal Cancer

Pain | Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Terminated

Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation

Multiple Myeloma and Plasma Cell Neoplasm | Drug/Agent Toxicity by Tissue/Organ

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Paclitaxel in Treating Patients With Advanced Head and Neck Cancer

Head and Neck Cancer

United States, South Africa
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Irinotecan and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer

Head and Neck Cancer

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Docetaxel and Gemcitabine in Treating Patients With Progressive Regional or Metastatic Bladder Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter | Urethral Cancer

United States, Puerto Rico, South Africa
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Paclitaxel Plus Estramustine in Treating Patients With Metastatic Prostate Cancer

Prostate Cancer

United States, South Africa
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Bladder Cancer

Bladder Cancer | Urethral Cancer

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Pancreas

Pancreatic Cancer

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With Advanced Non-Small Cell Lung Cancer

Lung Cancer

United States, Australia, Puerto Rico, South Africa
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer

Pancreatic Cancer

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Paclitaxel in Treating Patients With Metastatic or Recurrent Salivary Gland Cancer

Head and Neck Cancer

United States, South Africa
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Withdrawn

Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced or Refractory Solid Tumors

Cancer

Clinical Trials Sponsored by Eastern Cooperative Oncology Group

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