Clinical Trials Sponsored by Fondation Jerome Lejeune

Total 58 results

Institut Jerome Lejeune
Fondation Jérôme Lejeune

Completed

Down Syndrome and Continuous Positive Pressure Therapy (Morphee)

Obstructive Sleep Apnea Syndrome | Down Syndrome

France
Institut Jerome Lejeune
Fondation Jérôme Lejeune

Completed

Correlations Phenotype / Genotype in Down Syndrome (INTREPID)

Down Syndrome

France
Institut Jerome Lejeune
Fondation Jérôme Lejeune

Completed

Pilot Study of Auto-immune Abnormalities Associated With Down Syndrome (IMMUTRI)

Down Syndrome With and Without Auto Immune Abnormalities

France
Institut Jerome Lejeune
Fondation Jérôme Lejeune

Completed

Efficacy Study of Folinic Acid to Improve Mental Development of Children With Down Syndrome

Down Syndrome

France
Institut Jerome Lejeune

Recruiting

Genetic and Epigenetic Variations in Heterokaryotypic Monozygotic Twins Discordant for Down Syndrome (Colibri)

Down Syndrome

France
Institut Jerome Lejeune

Recruiting

Genetic Markers and Biomarkers in Patients With Intellectual Disabilities of Genetic Origin (BioJeL)

Intellectual Disability | Down Syndrome

France
Institut Jerome Lejeune

Recruiting

Cohort Study of Adult Patients With Down Syndrome at Risk of Developing Alzheimer's Disease (TriAL21)

Alzheimer Disease | Down Syndrome

France
Institut Jerome Lejeune
Hôpital Armand Trousseau

Completed

Anomalies of Nocturnal Gaz Exchanges in Patients With Down Syndrome

Down Syndrome

France
Institut Jerome Lejeune
Hôpital Necker-Enfants Malades

Active, not recruiting

Early Detection and Treatment of Respiratory Sleep Disorders in Children With Down Syndrome (RESPIRE21)

Down Syndrome | Obstructive Sleep Apnea of Newborn

France
King's College London
Parc de Salut Mar; Fondation Jérôme Lejeune

Recruiting

Elucidating Age-related Comorbidity Patterns in Down Syndrome (DS) (GO-DS21)

Down Syndrome

France, Spain, United Kingdom
Institut Jerome Lejeune
Central Hospital, Nancy, France; Hôpital Cochin

Completed

Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children (ACTHYF)

Down Syndrome

France
Perha Pharmaceuticals
Fondation Jérôme Lejeune; European Innovation Council; France 2030 program

Recruiting

Leucettinib-21 First-in-Human Phase 1 in Healthy Volunteers and Subjects With Down Syndrome and Alzheimer's Disease (LEUCETTA)

Healthy Volunteers | Down Syndrome | Alzheimer's Disease

France
University Hospital, Montpellier
Fondation Jérôme Lejeune; association autour des Williams; réseau de santé Maladies...

Unknown

Cognitive and Behavioral Therapy of Anxiety in Williams Syndrome (WILL-COPE)

Anxiety | Williams Syndrome

France
Henry M. Jackson Foundation for the Advancement...
Naval Hospital Camp Lejeune

Unknown

Preventing Obesity in Military Communities: Mother-Baby

Obesity | Overweight | Pregnancy

United States
Parc de Salut Mar
Hospital Infantil Universitario Niño Jesús, Madrid, Spain; Hospital Universitario... and other collaborators

Completed

Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS) (PERSEUS)

Down Syndrome | Fragile X Syndrome

Spain
University of Michigan
The Rome Foundation

Completed

Comparing the Effectiveness of Two Dietary Interventions for Fecal Incontinence

Fecal Incontinence

United States
British Columbia Cancer Agency
Genome British Columbia; BC Cancer Foundation

Unknown

Real-world Clinical Effectiveness of Whole Genome and Transcriptome Analysis to Guide Advanced Cancer Care

Metastatic Cancer | Advanced Cancer | Cancers That Cannot be Treated With Curative Intent
Andrew Penn
Heart and Stroke Foundation of Canada; Genome British Columbia; Bruker Daltonics and other collaborators

Completed

SpecTRA; An Observational Study of the Verification of Protein Biomarkers in Transient Ischemic Attack.

TIA

Canada
Fondazione Policlinico Universitario Agostino Gemelli...
University of Rome Tor Vergata; Fondazione Roma

Completed

Glucose Metabolism, Muscle Mass/Function and Inflammation in the Elderly

Diabetes Mellitus | Sarcopenia

Italy
Andrew Penn
Heart and Stroke Foundation of Canada; Genome British Columbia; Vancouver Island... and other collaborators

Completed

SpecTRA; A Study of the Validation of Protein Biomarkers in Transient Ischemic Attack

TIA

Canada
Fondazione Policlinico Universitario Agostino Gemelli...
San Camillo Hospital, Rome

Completed

Trauma Associated Bleeding: Effectiveness of an Early Coagulation Support Protocol

Major Trauma
Japanese Foundation for Cancer Research
Human Genome Center, Institute of Medical Science, University of Tokyo

Completed

Safety Study of Multiple Peptide Vaccine to Esophageal Cancer

Esophageal Cancer

Japan
European University of Rome
IRCSS Istituto Dermopatico dell'Immacolata, Fondazione Luigi Maria Monti

Completed

Effects of Guided Written Disclosure Protocol on Psychological Distress and Positive Functioning in Persons With Skin Diseases: a Randomized-controlled Trial

Skin Diseases | Psychological Distress | Emotional Stress | Disclosure

Italy
Rijnstate Hospital
Dutch Digestive Diseases Foundation; Sport Medisch Centrum Papendal; FormUpgrade... and other collaborators

Recruiting

The Effect of Intensive Physical Exercise on Fatigue and Quality of Life in Patients With Quiescent Inflammatory Bowel Disease (ENERGIZE-IBD)

Inflammatory Bowel Diseases

Netherlands
Bakulev Scientific Center of Cardiovascular Surgery
Foundation for the Support of Physical Culture and Sports BECOME A CHAMPION; Autonomous Non-Profit organization of additional education sports school BECOME A CHAMPION

Not yet recruiting

Neuromodulation of the Autonomic Nervous System in Athletes (NANSA)

Efficacy, Self | Fatigue, Mental | Fatigue; Muscle, Heart | Fatigue; Combat

Russian Federation
Canadian Cancer Trials Group
Cancer Research Institute, New York City; Personal Genome Diagnostics (PGDx); Mark Foundation for Cancer Research

Recruiting

Study of CTDNA Response Adaptive Immuno-Chemotherapy in NSCLC

Non-Small Cell Lung Cancer

Canada, United States
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Recruiting

Understanding Allergies and Sensitizations in Healthy and Allergic Individuals

Allergy

United States
University of Rome Tor Vergata
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; San Giuseppe Moscati... and other collaborators

Completed

Transanal Inspection and Management of Low ColoRectal Anastomosis Performed With a New Technique (TICRANT)

Anastomotic Leak

Italy
University of British Columbia
Canadian Institutes of Health Research (CIHR); Canada Foundation for Innovation and other collaborators

Recruiting

Pharmacogenomics of Drug Safety in Multiple Sclerosis

Multiple Sclerosis

Canada
Ospedale San Raffaele
University of Rome Tor Vergata; University of Genova; Fondazione G.B. Bietti,...

Recruiting

Subthreshold Laser Treatment for Reticular Pseudodrusen Secondary to Age-related Macular Degeneration (PASCAL-RPD)

Macular Degeneration, Dry | Macular Degeneration, Senile | Laser Burn of Retina | Macular Degeneration Intermediate

Italy
University of British Columbia
GlaxoSmithKline; Merck Sharp & Dohme LLC; Pfizer; Roche Pharma AG; AstraZeneca; Janssen... and other collaborators

Completed

The Implementation of Pharmacogenomics Into Primary Care in British Columbia (IPPC)

Pharmacogenetics
Royal Devon and Exeter NHS Foundation Trust
University of Chicago; University of Bergen; University of Rome Tor Vergata

Recruiting

Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome (iDEND)

Epilepsy | Intellectual Disability | ADHD | Neurodevelopmental Disorders | Autism Spectrum Disorder | Development Delay

United States, United Kingdom, Italy, Norway
University of Messina
Fondazione C.N.R./Regione Toscana "G. Monasterio", Pisa, Italy; Humanitas Hospital... and other collaborators

Completed

Clinical, Morphological and Functional Aspects in Myocarditis.

Myocarditis

Italy
San Camillo Hospital, Rome
Fondazione Italiana Sclerosi Multipla; Fondazione Don Carlo Gnocchi Onlus; University... and other collaborators

Recruiting

Home-based EXergames To impRove cognitivE Function in MUltiple Sclerosis (EXTREMUS)

Multiple Sclerosis

Italy
Texas Cardiac Arrhythmia Research Foundation
University of Rome Tor Vergata; Catholic University, Italy; Ospedale dell'Angelo... and other collaborators

Completed

Impact Of Different Ablation Approaches on Outcome In Coexistent Atrial Fibrillation and Flutter (APPROVAL)

Quality of Life | Atrial Arrhythmia

United States
University of British Columbia
Eli Lilly and Company; Merck Sharp & Dohme LLC; Pfizer; Canadian Institutes of... and other collaborators

Recruiting

National Active Surveillance Network and Pharmacogenomics of Adverse Drug Reactions in Children

Adverse Drug Reaction (ADR)

Canada
Azienda Socio Sanitaria Territoriale degli Spedali...
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; Niguarda Hospital; San... and other collaborators

Unknown

Activity of Abiraterone Acetate in the Management of Cushing's Syndrome in Patients With Adrenocortical Carcinoma (ABACUS)

Cushing Syndrome | Adrenocortical Carcinoma

Italy
Maastricht University Medical Center
King's College Hospital NHS Trust; Oslo University Hospital; Federico II University and other collaborators

Active, not recruiting

ORANGE SEGMENTS: Open Versus Laparoscopic Parenchymal Preserving Postero-Superior Liver Segment Resection

Liver Surgery

United Kingdom, Netherlands, Belgium, Italy, Norway, Russian Federation
Catholic University of the Sacred Heart
Texas Cardiac Arrhythmia Research Foundation; Cardiac Arrhythmia Research Center... and other collaborators

Unknown

Electrophysiologic and Morphologic Assessment of the Substrate to Guide Implantation of Defibrillators in Dilated Cardiomyopathy (EMOSIDD)

Dilated Cardiomyopathy | Implantable Cardioverter Defibrillator | Primary Prevention of Sudden Cardiac Death

Italy, United States
Fondazione Policlinico Universitario Agostino Gemelli...
Technische Universität Dresden; University of Debrecen; Koc University Hospital; Hospital de la Santa creu i Sant Pau - Barcelona and other collaborators

Not yet recruiting

Lung Cancer Multi-omics Digital Human Avatars for Integrating Precision Medicine Into Clinical Practice (LANTERN)

Non Small Cell Lung Cancer
Haukeland University Hospital
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Completed

Long-Term Sulfonylurea Response in KCNJ11 Neonatal Diabetes (SuResponsKIR)

Permanent Neonatal Diabetes Mellitus

Norway
Johns Hopkins University
Massachusetts General Hospital; Washington University School of Medicine; Emory... and other collaborators

Completed

Answer ALS: Individualized Initiative for ALS Discovery (AnswerALS)

Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Progressive Muscular Atrophy | Healthy Controls | Flail Arm ALS | Monomelic Amyotrophy | Asymptomatic ALS Gene Carriers

United States
Haukeland University Hospital
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Unknown

Long-Term Sulfonylurea Response in ABCC8 Neonatal Diabetes (SuResponsSUR) (SuResponsSUR)

Permanent Neonatal Diabetes Mellitus

Norway
Texas Cardiac Arrhythmia Research Foundation
Stanford University; University of Rome Tor Vergata; Case Western Reserve University and other collaborators

Completed

Ablation of Clinical Ventricular Tachycardia Versus Addition of Substrate Ablation on the Long Term Success Rate of VT Ablation (VISTA)

Ventricular Tachycardia

United States
Jeremy Keenan, MD, MPH
Johns Hopkins University; University of Pennsylvania; University of California... and other collaborators

Not yet recruiting

Parasitic Ulcer Treatment Trial (PUTT)

Acanthamoeba Keratitis

United States, Brazil, United Kingdom, India
Radboud University Medical Center
Maastricht University Medical Center; UMC Utrecht; Erasmus Medical Center; Catharina... and other collaborators

Completed

Clip Placement Following Colonic Endoscopic Mucosal Resection (EMR) (CLIPPER)

Bleeding | Polyp, Colonic

Netherlands
Euresist Network GEIE
Karolinska Institutet; Imperial College London; Heinrich-Heine University, Duesseldorf and other collaborators

Recruiting

Hospitalised COVID-19 Patients Cohort Study in the EuCARE Project (EuCARE-HOSP)

COVID-19

Vietnam, Sweden, Italy, Portugal, Germany, Kenya, Lithuania, Mexico, United Kingdom
Monica Ulivelli
Fondazione Italiana Sclerosi Multipla; Fondazione Policlinico Universitario... and other collaborators

Recruiting

Immunisation Status and Safety of Vaccines in Italian MS Patients

Multiple Sclerosis

Italy
Fondazione Poliambulanza Istituto Ospedaliero
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Universita di Verona; University... and other collaborators

Completed

Perioperative Outcomes of Simultaneous Colorectal and Liver Resections (SIMULT)

Colorectal Cancer Metastatic | Surgical Procedure, Unspecified

Italy
University of Turin, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Federico II University and other collaborators

Recruiting

Complete Mesocolic Excision in Comparison With Conventional Surgery for the Right Colon Cancer (CoME-In)

Colon Cancer

Italy

Clinical Trials Sponsored by Fondation Jerome Lejeune

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Latvia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations