Clinical Trials Sponsored by Fraunhofer-Institute of Toxicology and Experimental Medicine

Total 61 results

Fraunhofer-Institute of Toxicology and Experimental...

Completed

Quantification of Exhaled Particles to Identify Airborne Transmission Risks of COVID-19 (QUELLE)

Healthy

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Characterization of the Inhibitory Effects of Fevipiprant (QAW039) on Activation of Eosinophils and ILC2 Cells by Prostaglandin D2 Metabolites (18-03 EONOV)

Atopic Asthma

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

The Role of Pollen Starch Granules in Pollen Challenge Studies in the Fraunhofer Environmental Exposure Unit

Asthma | Seasonal Allergic Rhinitis

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Study to Compare the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Placebo on Symptoms in Patients With Allergic Rhinitis Within/Out of Season

Rhinitis | Atopy

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Terminated

Effect of an Immunotoxin on Activated Human Macrophages in Those With Allergic Rhinitis or Mild Intermittent Asthma

Rhinitis | Bronchial Asthma | Atopy

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

A Pilot Monocenter Study to Assess Cellular and Soluble Biomarkers in Nasal Secretions

Healthy Subjects | Seasonal Allergic Rhinitis

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Second Follow-up Study of COPD Patients and Healthy Controls for Evaluation of Predictive Non-coding RNA Biomarkers (Ribo III)

Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Impact of Carrier Solutions for House Dust Mite Allergen on Allergic Reactions (SIMBA)

Allergic Rhinitis

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Investigation of Secreted Phosphoproteins and PiP3 (Phosphoinositolphospat 3) in Sputum

Healthy | Smoking, Cigarette

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Monocenter 6-period Study in Patients With Seasonal Allergic Rhinitis to Birch Pollen to Establish a Challenge Model With Natural Birch Pollen in an Environmental Challenge Chamber (ECC)

Seasonal Allergic Rhinitis
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Validation of an Environmental Exposure Chamber for Inhalation Studies With House Dust Mite Allergen in Patients With Allergic Rhinitis

Allergy to House Dust Mite

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Novel Noninvasive Techniques to Study Neutrophil Airway Inflammation in an Ozone Challenge Model

Healthy Subjects

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Recruiting

Development of a Novel Non-invasive Inflammometry Following Allergen Challenge in Patients With Mild Allergic Asthma

Mild Allergic Asthma

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Recruiting

Biosensor and Environmental Sensor Development Within the REMEDIA Project

Healthy | Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Recruiting

Threshold Concentrations for Ragweed and Birch Pollen in Seasonal Allergic Rhinitis (UBAMBI)

Allergic Rhinitis | Seasonal Allergic Rhinitis | Birch Pollen Allergy | Ragweed Allergy

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Characterization of Aerosol Generation and Transport in the Human Lung of Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Follow-up-study of COPD Patients and Healthy Controls for Evaluation of Predictive Non-coding RNA Biomarkers (Ribo2)

Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Suitability of a Low Dose Lipopolysaccharide (LPS) Inhalation as a Challenge Model

Healthy

Germany
Fraunhofer-Institute of Toxicology and Experimental...

Completed

Characterization of Aerosol Generation and Transport in the Human Lung

Asthma
Fraunhofer-Institute of Toxicology and Experimental...
GlaxoSmithKline

Completed

Study to Assess the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Cetirizine Alone on Symptoms in Patients With Allergic Rhinitis

Seasonal Allergic Rhinitis

Germany
Fraunhofer-Institute of Toxicology and Experimental...
AstraZeneca

Completed

Use of Exhaled Particles to Assess Lung Pharmacokinetics (EXPLORE)

Healthy | Lung Pharmacokinetic

Germany
Fraunhofer-Institute of Toxicology and Experimental...
AstraZeneca

Completed

Lung Pharmacokinetics (PK) in Epithelial Lining Fluid (ELF)

Healthy

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Boehringer Ingelheim

Completed

Effects of Spiolto® Respimat® (Tiotropium/Olodaterol) on Cardiac Function in Hyperinflated COPD Subjects

Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...
UCB Pharma

Completed

Evaluation of Nasal Inflammatory Biomarkers

Seasonal Allergic Rhinitis

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Skin Responses and T Cell Immunology After House Dust Mite Exposure in Sensitized Atopic Dermatitis Patients (CODES)

Atopic Dermatitis | House Dust Mite Allergy

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Study to Assess the Effect of "Eucerin AtopiControl" on Dermal Symptoms in Patients With Atopic Dermatitis

Atopic Dermatitis | Allergy Pollen

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Effect of Pollen Challenges on Dermal Symptoms in Patients With Atopic Dermatitis (Neurop)

Atopic Dermatitis
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Influence of Diesel Exhaust Particles (DEP) With and Without Organic Compounds on the Allergic Inflammation in Asthmatic Subjects

Asthma

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Development of Novel Non-invasive Inflammometry Following Lipopolysaccharide, Endotoxin (LPS) Challenge in Healthy Volunteers

Healthy

Germany
Hannover Medical School
Fraunhofer-Institute of Toxicology and Experimental Medicine

Unknown

Experimental Exposure to Air Pollutants and Sympathetic Nerve Activity in Human Subjects (Particles)

Cardiovascular Morbidity

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Pilot Study for Cell Based Therapies in Patients With Asthma

Asthma | Allergic Rhinitis
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Study to Explore the Effects of Two Hour Inhalation of Ultrafine Carbon Black Particles on Airway Inflammation in Asthmatics

Asthma

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Institute for Pharmacology and Toxicology, RWTH Aachen

Completed

Demonstration of Broncholytic Effects in Subjects With Obstructive Airway Diseases by Low Frequency Ultrasound (Pabes)

Healthy Volunteers | COPD GOLD I to IV | Asthma GINA 1 to 4

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Hannover Medical School

Completed

Ex Vivo Effect of Surfactant Protein D on Pulmonary Cells in Patients With Asthma and Pilot Study to Assess Local Inflammation Induced by Segmental Allergen Challenge by Magnetic Resonance Imaging

Mild Intermittent Asthma (Gina 1)

Germany
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Ex Vivo Effect of Surfactant Protein D on Pulmonary Immune Cells Derived From Bronchoalveolar Lavage After Segmental Allergen Challenge in Patients With Asthma

Asthma

Germany
Prof. Dr. Jens Hohlfeld

Completed

Activation of Apoptosis-related Receptors on Alveolar Macrophages

Chronic Obstructive Pulmonary Disease

Germany
Fraunhofer-Institute of Toxicology and Experimental...
M et P Pharma AG

Completed

Effect of the Nasal Gel "Nascum®-Plus" on Allergic Symptoms (NAPO)

Rhinitis, Allergic, Seasonal

Germany
Fraunhofer-Institute of Toxicology and Experimental...
Federal Institute for Occupational Safety and Health (BAuA)/Germany)

Completed

Pharmacokinetics of Enrofloxacin in Plasma and Urine (EnroHuman)

Healthy

Germany
Prof. Dr. Jens Hohlfeld
Hannover Medical School

Completed

Breath Volatile Organic Compounds Patterns of Lung Transplant Patients With Chronic Lung Allograft Dysfunction

Chronic Lung Allograft Dysfunction (CLAD)

Germany
University Medical Centre Ljubljana
University of Ljubljana, Faculty of Medicine, Institute of Pharmacology and...

Completed

Role of the ATP7A Transporter in Ovarian Cancer (ATHOC)

Gynecologic Cancer | Ovarian Cancer | Chemotherapy Effect | High Grade Serous Carcinoma

Slovenia
Institute for Clinical and Experimental Medicine
Czech Academy of Sciences

Recruiting

Gluten-free Diet in PSC and IBD

Biliary Tract Diseases | Ulcerative Colitis | Primary Sclerosing Cholangitis | Intestinal Disease | Biliary Disease Tract

Czechia
University of Ostrava
Institute for Clinical and Experimental Medicine; Vitkovice Hospital

Active, not recruiting

Small Bowel Diversion

Obesity | Type2 Diabetes

Czechia
Institute for Clinical and Experimental Medicine
Ministry of Health, Czech Republic

Completed

Effect of Angiotensin Receptor Blockade on Insulin Resistance and Adipose Tissue Cytokines in Type 2 Diabetes

Insulin Resistance | Type 2 Diabetes

Czech Republic
Institute for Clinical and Experimental Medicine
Ministry of Health, Czech Republic

Unknown

Polyclonal Anti-T-Lymphocyte Globulin (ATG) in Type 1 Diabetes

Diabetes Mellitus, Type 1

Czech Republic
Prof Michael Scott
University of Ulster; National University of Ireland, Maynooth; University of... and other collaborators

Completed

SHAPES: Supporting Multimorbid Older People

Heart Failure | Diabetes Mellitus | Diabetes

United Kingdom
Institute for Clinical and Experimental Medicine
Institute of Animal Physiology and Genetics Academy of Science Czech Republic

Completed

Faecal Bacteriotherapy for Ulcerative Colitis (FACTU)

Ulcerative Colitis

Czechia
Institute for Clinical and Experimental Medicine
Charles University, Czech Republic; 3rd Department of Internal Medicine - Cardiology

Unknown

Continuous Versus Discontinuous Design of Encircling Lesions During Ablation for Atrial Fibrillation (CDAF)

Atrial Fibrillation

Czechia
Göteborg University
Institute of Aviation Medicine, Oslo, Norway; Naval Health Research Center; Fraunhofer... and other collaborators

Enrolling by invitation

Human Impact Exposure Onboard High-Speed Boats (MASHIEN)

Traumatic Injury of Spine | Traumatic Head Injury | Traumatic Injuries

Sweden
Institute for Clinical and Experimental Medicine
Centre of Cardiovascular and Transplantation Surgery, Czech Republic; St. Anne...

Recruiting

Efficacy and Safety Of Alirocumab to Prevent Early Cardiac Allograft Vasculopathy in Recent Heart Transplant Recipients (ACAV)

Cardiac Allograft Vasculopathy

Czechia
Institute of Health Information and Statistics...
Institute for Clinical and Experimental Medicine; University Hospital Olomouc; The Institute of Molecular and Translational Medicine, Czech Republic and other collaborators

Completed

COVID-19: SARS-CoV-2-CZ-PREVAL-II Study

COVID-19 | SARS-CoV-2 Infection

Czechia

Clinical Trials Sponsored by Fraunhofer-Institute of Toxicology and Experimental Medicine

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