Clinical Trials Sponsored by General Genetics Corporation

Total 206 results

General Genetics Corporation
Syntactx

Unknown

Pharmacogenomic Testing Of the Elderly To Reduce Morbidity (POETRY)

Genetics of Drug Metabolism

United States, Puerto Rico
Targeted Genetics Corporation

Completed

Phase 1 Dose Escalation Study of Intra-Articular Administration of tgAAC94

Rheumatoid Arthritis

Canada, United States
Targeted Genetics Corporation

Completed

Study of Intra-articular Delivery of tgAAC94 in Inflammatory Arthritis Subjects

Arthritis, Rheumatoid | Arthritis, Psoriatic | Ankylosing Spondylitis

United States
NewLink Genetics Corporation

Completed

Study of IDO Inhibitor in Combination With Checkpoint Inhibitors for Adult Patients With Metastatic Melanoma

Metastatic Melanoma | Stage IV Melanoma | Stage III Melanoma

United States
NewLink Genetics Corporation

Completed

Vaccine Treatment for Surgically Resected Pancreatic Cancer

Pancreatic Cancer

United States
NewLink Genetics Corporation

Terminated

IDO Inhibitor Study for Relapsed or Refractory Solid Tumors (D-1MT)

Melanoma | Breast Cancer | Pancreatic Cancer | Lung Cancer | Solid Tumors

United States
NewLink Genetics Corporation

Completed

Oral Bioavailability,and Food Effect Study and Single Ascending Dose PK Study in Healthy Male Volunteers

Healthy

Canada
NewLink Genetics Corporation

Terminated

Immunotherapy and SBRT Study in Borderline Resectable Pancreatic Cancer

Pancreatic Cancer | Pancreatic Carcinoma Non-resectable

United States
NewLink Genetics Corporation

Terminated

Immunotherapy Study in Borderline Resectable or Locally Advanced Unresectable Pancreatic Cancer (PILLAR)

Pancreatic Cancer | Locally Advanced Malignant Neoplasm | Pancreatic Carcinoma Non-resectable

United States
NewLink Genetics Corporation

Terminated

Low Dose Vaccine Study for Surgically Resected Pancreatic Cancer

Pancreatic Cancer

United States
NewLink Genetics Corporation

Completed

Single Ascending Dose PK, Oral Bioavailability and Food Effect Study in Healthy Male Volunteers (NLG2111)

Healthy

United States
NewLink Genetics Corporation

Completed

Study of CRLX101 (NLG207) in the Treatment of Advanced Solid Tumors

Cancer | Solid Tumor

United States
NewLink Genetics Corporation

Terminated

Immunotherapy Study in Progressive or Relapsed Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Recurrent | Progression of Non-small Cell Lung Cancer

United States
NewLink Genetics Corporation

Completed

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

Glioma | Glioblastoma Multiforme | Gliosarcoma | Malignant Brain Tumor

United States
NewLink Genetics Corporation

Terminated

Long Term Follow-Up Study for Subjects Previously Treated With Algenpantucel-L (HyperAcute-Pancreas) Immunotherapy

Pancreatic Cancer

United States
NewLink Genetics Corporation

Terminated

Immunotherapy Combination Study in Advanced Previously Treated Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Recurrent | Progression of Non-small Cell Lung Cancer

United States
NewLink Genetics Corporation

Withdrawn

Efficacy Study of Maintenance IT-101 Therapy for Ovarian Cancer Patients.

Cancer | Ovarian Cancer | Solid Tumor

United States
NewLink Genetics Corporation

Terminated

Phase 1/2a Dose-Escalation Study of CRLX301 in Patients With Advanced Solid Tumors

Advanced Solid Tumor Malignancy

United States
NewLink Genetics Corporation

Completed

Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors

Glioma | Glioblastoma Multiforme | Gliosarcoma | Ependymoma | Medulloblastoma | Diffuse Intrinsic Pontine Glioma | Malignant Brain Tumor | Primary CNS Tumor

United States
NewLink Genetics Corporation

Completed

Study of IDO Inhibitor in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Metastatic Pancreatic Cancer

Metastatic Pancreatic Adenocarcinoma | Metastatic Pancreatic Cancer

United States
NewLink Genetics Corporation

Terminated

Alternative Dosing for CRLX101(NLG207) Alone, With Avastin and With mFOLFOX6 in Advanced Solid Tumors

Solid Tumors

United States
NewLink Genetics Corporation

Completed

Vaccine Study for Surgically Resected Pancreatic Cancer

Pancreatic Cancer

United States
NewLink Genetics Corporation

Terminated

Vaccine Maintenance Treatment for Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung

United States
NewLink Genetics Corporation

Completed

Immunotherapy Study for Surgically Resected Pancreatic Cancer

Pancreatic Cancer

United States
NewLink Genetics Corporation

Completed

Study of Chemotherapy in Combination With IDO Inhibitor in Metastatic Breast Cancer

Metastatic Breast Cancer

United States, Poland
NewLink Genetics Corporation

Terminated

Vaccine Treatment for Advanced Breast Cancer

Breast Cancer

United States
Global Kinetics Corporation

Active, not recruiting

Evaluation of the Personal KinetiGraph™ (PKG™) to Improve Insight Into Parkinson's Disease Status (APPRISE)

Parkinson Disease

United States
Global Kinetics Corporation

Terminated

Utilization of Target Ranges to Treat Parkinson's Disease With the PKG (TARGET-PD)

Parkinson Disease

United States
NewLink Genetics Corporation

Terminated

Immunotherapy Study for Patients With Stage IV Melanoma

Metastatic Melanoma | Stage IV Melanoma

United States
NewLink Genetics Corporation

Terminated

A Study of Indoximod or Placebo Plus Pembrolizumab or Nivolumab for Subjects With Unresectable or Metastatic Melanoma (NLG2107)

Melanoma

United States
NewLink Genetics Corporation

Completed

Immunotherapy Study for Metastatic Renal Cell Cancer

Metastatic Renal Cell Carcinoma | Recurrent Renal Cell Carcinoma | Metastatic Kidney Cancer | Refractory Renal Cell Carcinoma | Metastatic Clear-cell Renal Cancer

United States
NewLink Genetics Corporation

Completed

NLG802 Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors

Solid Tumor

United States
NewLink Genetics Corporation

Completed

A Study of Indoximod in Combination With (7+3) Chemotherapy in Patients With Newly Diagnosed Acute Myeloid Leukemia

Acute Myeloid Leukemia

United States
NewLink Genetics Corporation

Completed

A Phase 2 Study of CRLX101(NLG207) in Patients With Advanced Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

Russian Federation, Ukraine
NewLink Genetics Corporation

Completed

Vaccine Treatment for Advanced Malignant Melanoma

Malignant Melanoma

United States
NewLink Genetics Corporation

Completed

Vaccine Treatment for Hormone Refractory Prostate Cancer

Prostate Cancer

United States
NewLink Genetics Corporation

Completed

CRLX101(NLG207) in Combination With Bevacizumab for Metastatic Renal Cell Carcinoma (mRCC) Versus Standard of Care (SOC)

Metastatic Renal Cell Carcinoma

Korea, Republic of, United States
NewLink Genetics Corporation

Terminated

A Study of CRLX101(NLG207) in Combination With Weekly Paclitaxel in Patients With Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Ovarian Cancer

United States
Global Kinetics Corporation

Recruiting

Personal KinetiGraph® Clinical Validation Study

Parkinson Disease | Movement Disorders

United States
Global Kinetics Corporation

Withdrawn

Utilization of Target Ranges to Treat Persons With Parkinson's Disease by Objective Measurement Using the PKG (TARGET-PwP)

Parkinson Disease
Genesis Medtech Corporation

Recruiting

Clinical Trial in China

Diseases of Aortic Valve | Aortic Regurgitation Disease

China
Genesis Medtech Corporation

Active, not recruiting

SOLSTICE Trial in China

Coronary Artery Disease | Calcifications Vascular

China
Ochsner Health System
NewLink Genetics Corporation

Unknown

A Phase II Study of an Anti-Tumor Immunotherapy Regimen Comprised of Pegylated Interferon-Alpha 2b and HyperAcute Melanoma Vaccine for Subjects With Advanced Melanoma

Melanoma

United States
Targeted Genetics Corporation
Cystic Fibrosis Foundation

Terminated

Safety and Efficacy of Recombinant Adeno-Associated Virus Containing the CFTR Gene in the Treatment of Cystic Fibrosis

Cystic Fibrosis

United States
Genesis Medtech Corporation

Recruiting

Clinical Trial in China for Aortic Valve Stenosis

Diseases of Aortic Valve | Aortic Stenosis Disease

China
Genesis Medtech Corporation

Active, not recruiting

SOLUTION Trial in China

Peripheral Arterial Disease | Calcifications Vascular

China
General Oncology, Inc.
Myriad Genetics, Inc.

Recruiting

SHARON: A Clinical Trial for Metastatic Cancer With a BRCA or PALB2 Mutation Using Chemotherapy and Patients' Own Stem Cells

Pancreatic Cancer | Pancreatic Ductal Adenocarcinoma | Pancreatic Cancer Stage IV | Breast Cancer Stage IV | BRCA1 Mutation | BRCA2 Mutation | Pancreatic Acinar Cell Carcinoma | Metastatic Pancreatic Cancer | Breast Cancer Metastatic | HER2-negative Breast Cancer | Metastatic Pancreatic Ductal Adenocarcinoma and other conditions

United States
International AIDS Vaccine Initiative
Targeted Genetics Corporation

Completed

Safety and Immunogenicity Study of tgAAC09, an HIV Vaccine in an Adeno-associated Virus (AAV) Capsid (TGC14F)

HIV Infections | Human Immunodeficiency Virus Infections

Uganda, South Africa, Zambia
Helsinki University Central Hospital
deCODE genetics

Active, not recruiting

Biomarkers of Neuropathic Pain in Women Treated for Breast Cancer

Breast Cancer | Neuropathic Pain

Finland
General Biologicals Corporation

Completed

Development of a Molecular Diagnosing Platform for Relieving Periodontal Symptoms

Periodontal Diseases | Peri-Implantitis

Clinical Trials Sponsored by General Genetics Corporation

Sponsors and Collaborators

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