Clinical Trials Sponsored by Geron Corporation

Total 6481 results

Geron Corporation

Completed

Imetelstat Sodium in Treating Participants With Primary or Secondary Myelofibrosis

Primary Myelofibrosis | Secondary Myelofibrosis | Myeloid Malignancies

United States
Geron Corporation

Completed

Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia Vera (ET/PV)

Polycythemia Vera | Essential Thrombocythemia

United States, Germany, Switzerland
Geron Corporation

Completed

Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy in Non-small Cell Lung Cancer (NSCLC)

Non-small Cell Lung Cancer

United States, Canada, Germany
Geron Corporation

Completed

Safety and Dose Study of GRN163L and Velcade to Treat Patients With Refractory or Relapsed Myeloma

Multiple Myeloma

United States
Geron Corporation

Completed

Safety and Dose Study of GRN163L to Treat Patients With Chronic Lymphoproliferative Disease(CLD)

Chronic Lymphoproliferative Diseases

United States
Geron Corporation

Active, not recruiting

Study to Evaluate Imetelstat (GRN163L) in Subjects With International Prognostic Scoring System (IPSS) Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes

United States, Canada, Belgium, Spain, Czechia, Korea, Republic of, United Kingdom, Netherlands, Israel, Germany, Russian Federation, Switzerland, Italy, France, Turkey, Poland, Ukraine
Geron Corporation

Completed

Study to Evaluate Activity of 2 Dose Levels of Imetelstat in Participants With Intermediate-2 or High-Risk Myelofibrosis (MF) Previously Treated With Janus Kinase (JAK) Inhibitor

Myelofibrosis

United States, France, Italy, United Kingdom, Belgium, Germany, Taiwan, Spain, Israel, Korea, Republic of, Canada
Geron Corporation

Completed

Open Label Study With Imetelstat to Determine Effect of Imetelstat in Patients w/ Previously Treated Multiple Myeloma

Multiple Myeloma

United States
Geron Corporation

Completed

Imetelstat in Combination With Paclitaxel (With or Without Bevacizumab) in Patients With Locally Recurrent or Metastatic Breast Cancer

Locally Recurrent or Metastatic Breast Cancer

United States, Canada
Geron Corporation

Completed

Study of GRN163L With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Non Small Cell Lung Cancer

Lung Cancer

United States
Geron Corporation

Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat in Combination With Ruxolitinib in Participants With Myelofibrosis

Myelofibrosis

United States
Geron Corporation

Recruiting

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

Myelofibrosis

United States, Australia, Italy, India, United Kingdom, Israel, Taiwan, Poland, Malaysia, Argentina, Spain, Turkey, Belgium, Germany, Austria, Brazil, Bulgaria, Colombia, Denmark, France, Georgia, Hungary, Korea, Republic of, Portugal, ... and more
Geron Corporation

Available

Expanded Access for Treatment With Imetelstat

Myelodysplastic Syndromes
Geron Corporation

Completed

Safety and Dose Study of GRN163L Administered to Treat Patients With Refractory or Relapsed Multiple Myeloma

Multiple Myeloma

United States
Geron Corporation

Completed

Safety and Dose Study of GRN163L Administered to Patients With Refractory or Relapsed Solid Tumor Malignancies

Solid Tumor Malignancies

United States
Geron Corporation

Completed

A Study of GRN163L With Paclitaxel and Bevacizumab to Treat Patients With Locally Recurrent Or Metastatic Breast Cancer

Breast Cancer

United States
Geon Corporation

Active, not recruiting

The Clinical Performance Validation of Electronic Thermometer and Infrared Thermometers

Healthy | Febrile

Taiwan
Indiana University
Breast Cancer Research Foundation; Geron Corporation

Completed

A Study Inhibiting Telomerase to Reverse Trastuzumab Resistance in HER2+ Breast Cancer

Breast Neoplasms

United States
NCIC Clinical Trials Group
Geron Corporation

Withdrawn

Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma

Neuroblastoma

Canada
Heron Therapeutics

Active, not recruiting

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.

Analgesia

United States
Heron Therapeutics

Completed

Phase 2 Bunionectomy HTX-011 Administration Study

Postoperative Pain

United States
Heron Therapeutics

Terminated

Aprepitant Injectable Emulsion in Patients With COVID-19 (GUARDS-1)

COVID-19

United States
Heron Therapeutics

Completed

Herniorrhaphy Study for Opioid Elimination

Analgesia

United States
Heron Therapeutics

Completed

Total Knee Arthroplasty Infiltration Study for Postoperative Analgesia

Postoperative Pain

United States
Heron Therapeutics

Completed

Bupivacaine HCl PK and Safety in Augmentation Mammoplasty

Analgesia

United States
Heron Therapeutics

Completed

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.

Postoperative Pain | Multimodal Analgesia | Total Shoulder Arthroplasty

United States
Heron Therapeutics

Completed

Evaluation of the Efficacy and Safety of HTX-011 for Postoperative Analgesia Following Abdominoplasty Surgery

Postoperative Pain

United States
Heron Therapeutics

Active, not recruiting

Safety Study of Repeat Doses of SUSTOL in Adults

Chemotherapy-Induced Nausea and Vomiting (CINV)

United States
Heron Therapeutics

Completed

HTX-011 in Spinal Surgery

Lumbar Laminectomy | Post-Operative Pain

United States
Heron Therapeutics

Withdrawn

Pediatric Postoperative Analgesia Herniorrhaphy Study

Analgesia

United States
Heron Therapeutics

Completed

HTX-011 Administration Study in Planned Caesarean Section Procedure

Analgesia

United States
Heron Therapeutics

Completed

APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Nausea and Vomiting

United States
Heron Therapeutics

Completed

A Phase 2, Two-Part Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy (HTX-011)

Analgesia

United States
Heron Therapeutics

Completed

A Prospective, Multicenter, Study of APF530 (Granisetron) SC for Prevention of CINV in Patients Receiving HEC

Chemotherapy-induced Nausea and Vomiting

United States
Heron Therapeutics

Completed

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE

Analgesia

United States
Heron Therapeutics

Completed

A Pilot Study to Investigate the Safety, Efficacy, Pharmacokinetics and Bioavailability of HTX-011, HTX-002, or HTX-009 Administered Via Injection and/or Topical Application Following Unilateral Open Inguinal Herniorrhaphy

Postoperative Pain

United States
Heron Therapeutics

Completed

Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy

Postoperative Pain | Bunions

United States
Heron Therapeutics

Completed

Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen

Analgesia

United States
Heron Therapeutics

Completed

Dose-Escalation Study of HTX-034 Following Bunionectomy

Bunions

United States
Heron Therapeutics

Completed

Phase 2B Upper Extremity Nerve Block Study

Postoperative Pain

United States
Heron Therapeutics

Completed

Bunionectomy Study for Postoperative Analgesia (EPOCH 1)

Postoperative Pain

United States
Heron Therapeutics

Completed

Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)

Postoperative Pain

United States, Belgium
Heron Therapeutics

Completed

Phase 2 Herniorrhaphy Study for Opioid Elimination

Postoperative Pain

United States
Heron Therapeutics

Completed

Extended Delivery of Bupivacaine Study in Herniorrhaphy

Analgesia

United States
Heron Therapeutics

Completed

A Phase I Study of the Effects of APF530 Exposure, Granisetron and Moxifloxacin

Healthy

United States
Leonard-Meron Biosciences, Inc.

Recruiting

Mino-Lok Therapy (MLT) for the Treatment of CRBSI/CLABSI

Catheter-related Infections

United States, Puerto Rico
Leonard-Meron Biosciences, Inc.

Available

Expanded Access: Mino-Lok Therapy (MLT) for the Treatment of CRBSI/CLABSI (MLK)

Catheter-Related Infections

United States, Puerto Rico
GenMont Biotech Incorporation
Biomedical Development Corporation

Completed

the Efficacy and Safety of Probiotics eN-Lac® Capsules of Children With Perennial Allergic Rhinitis (PAR)

Probiotics | Perennial Allergic Rhinitis | Lactobacillus Paracasei GMNL-32 (eN-Lac®)

Taiwan
Gero Bunniger

Recruiting

The Right Heart During and After Pregnancy - an Echocardiographic Study (EVA)

Pregnancy Related

Germany
MAHAN Trust
Stitching Geron and Cordaid, The Netherlands.; Caring Friends, Mumbai

Completed

Home Based Child Care to Reduce Mortality and Malnutrition in Tribal Children of Melghat, India: CRCT (HBCC)

Diarrhea | Malaria | Neonatal Sepsis | Birth Asphyxia | Acute Respiratory Tract Infections

India

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