Clinical Trials Sponsored by Glaxo Wellcome

Total 434 results

National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

Comparison of Three Anti-HIV Drug Combinations in HIV-Infected Patients With No Symptoms of the Disease

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche; Glaxo Wellcome

Completed

A Randomized, Double Blind, Comparative Study of Dideoxycytidine (ddC) Alone or ddC/AZT Combination Versus Zidovudine (ZDV) Alone in Patients With HIV Infection Who Have Received Prior ZDV Therapy

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

Evaluation of Patients Who Have Not Had Success With Zidovudine

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

Comparison of Brovavir Versus Acyclovir in the Treatment of Herpes in HIV-Infected Patients

HIV Infections | Chickenpox

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Randomized, Comparative Trial of Zidovudine (AZT) Versus 2',3'-Didehydro-3'-Deoxythymidine (Stavudine; d4T) in Children With HIV Infection

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Comparative Study of a Combination of Zidovudine, Didanosine, and Double-Blinded Nevirapine Versus a Combination of Zidovudine and Didanosine

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Randomized, Double-Blind, Four-Arm Study Comparing Combination Nucleoside, Alternating Nucleoside, and Triple-Drug Therapy for the Treatment of Advanced HIV Disease (CD4 <= 50/mm3)

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Phase I/II, Open Label Study to Evaluate the Antiviral Potential of Combination Zidovudine and 2' 3'-Dideoxyinosine (Didanosine) in Patients With Asymptomatic HIV Disease

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia Complex

HIV Infections | AIDS Dementia Complex

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Randomized, Double-Blind Phase II/III Trial of Monotherapy vs. Combination Therapy With Nucleoside Analogs in HIV-Infected Persons With CD4 Cells of 200-500/mm3

HIV Infections

United States, Puerto Rico, Tanzania
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Randomized Comparative Trial of Zidovudine (AZT) Versus 2',3'-Dideoxyinosine (ddI) Versus AZT Plus ddI in Symptomatic HIV-Infected Children

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

The Effects of Anti-HIV Drugs in HIV-Infected Patients Who Do Not Have AIDS

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Comparison of Three Treatments for Advanced HIV Disease in Patients Who Have Received Nucleoside Therapy in the Past

HIV Infections

United States, Tanzania, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche; Glaxo Wellcome

Completed

The Safety of Zidovudine Plus Interferon-Alpha in HIV-Infected Children

HIV Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Multicenter Phase II Double-Blind Exploratory Study to Evaluate Differences Among Various Zidovudine/Didanosine Regimens on Quantitative Measures of Viral Burden in Relatively Early HIV-1 Infection

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
G D Searle; Glaxo Wellcome

Completed

A Phase II Double-Blind Study of Two Doses of SC-49483 in Combination With Zidovudine (ZDV) Versus ZDV

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

A Comparison of Zidovudine Plus Lamivudine Versus ddI Used Alone or in Combination With Zidovudine in HIV-1 Infected Children

HIV Infections

United States, Puerto Rico
Gilead Sciences
Glaxo Wellcome; Dupont Applied Biosciences

Completed

Safety and Effectiveness of Giving Adefovir Dipivoxil Plus Abacavir Plus Efavirenz Plus Amprenavir to HIV-Infected Patients Who Have Failed to Respond to Previous Protease Inhibitor Treatment

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...
Agouron Pharmaceuticals; Glaxo Wellcome; Chiron Corporation

Completed

Effectiveness of Adding Interleukin-2 to Anti-HIV Drugs in Patients Recently Infected With HIV

HIV Infections

United States
US Department of Veterans Affairs
Glaxo Wellcome; Parke-Davis

Completed

Does Gabapentin and Lamotriginel Have Significantly Fewer Side-effects While Providing Equal or Better Seizure Control Than the Current Drug Choice, Carbamazepine, for the Treatment of Seizures in the Elderly.

Seizures

United States
Kineta Inc.
Wellcome Trust

Completed

Multiple Ascending Oral Dose 14-Day Trial of LHF-535 in Healthy Participants

Healthy

Australia
GE Healthcare
Wellcome Trust

Terminated

Development of a MR Scanner Capable of Being Sited in a Neonatal Intensive Care Unit (Firefly)

Image Evaluation

United States
GE Healthcare
Wellcome Trust

Completed

Development of a MR Scanner Capable of Being Sited in a Neonatal Intensive Care Unit (Firefly Sheffield)

Neonatal Neuroimaging

United Kingdom
Summit Therapeutics
Wellcome Trust

Completed

A Study of SMT19969 Compared With Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhoea (CDAD)

Clostridium Difficile Infection

United States, Canada
University of Oxford
Wellcome Trust

Recruiting

A Controlled Human Vivax Malaria Infection Study Through Inoculation of Infected Erythrocytes (MIST2)

Plasmodium Vivax Infection

Thailand
Imperial College London
Wellcome Trust

Recruiting

Additional Treatments to the Local Tumour for Metastatic Prostate Cancer: Assessment of Novel Treatment Algorithms (IP2-ATLANTA)

Prostate Cancer | Metastatic Prostate Cancer

United Kingdom
University of Oxford
Wellcome Trust

Completed

Complement 2: Blood Donations to Develop Vaccines Against Infectious Diseases (C2)

Complement Mediated Bacterial Killing in Healthy Adults

United Kingdom
University of Exeter
Wellcome Trust

Completed

Forearm Immobilization, Metabolic Health, and Nutrition

Healthy

United Kingdom
Imperial College London
Wellcome Trust

Completed

Guanfacine for the Treatment of Spatial Neglect and Impaired Vigilance (GASNIV)

Stroke | Hemispatial Neglect

United Kingdom
Queen's University, Belfast
Wellcome Trust

Completed

Tailored Mediterranean Lifestyle Education in Patients With Mild Cognitive Impairment

Mild Cognitive Impairment

United Kingdom
University of KwaZulu
Wellcome Trust

Completed

Vertical Transmission Study (VTS)

HIV

South Africa
Johns Hopkins University
Wellcome Trust

Completed

Effect of Intensive Fly Control on Trachoma and Ocular Chlamydia Infection in Tanzania

Trachoma

United States
University of Oxford
Wellcome Trust

Unknown

Neonatal Sepsis and GBS Carriage Study (NSS)

Neonatal Sepsis | Maternal GBS Carriage

Thailand
University of Oxford
Wellcome Trust

Recruiting

Mechanisms of Neurodynamic Treatments (MONET)

Carpal Tunnel Syndrome | Physiotherapy | Neurodynamic Treatment | Nerve Mobilisation | Diffusion MRI | Mechanistic Trial

United Kingdom
Queen's University, Belfast
Wellcome Trust

Completed

Tailored Mediterranean Lifestyle Education in Participants With Subjective Cognitive Impairment

Subjective Cognitive Impairment

United Kingdom
University of Oxford
Wellcome Trust

Completed

Oxford Haemodynamic Adaptation to Reduce Pulsatility Trial (OxHARP)

Small Vessel Cerebrovascular Disease

United Kingdom
University of Exeter
Wellcome Trust

Completed

Forearm Immobilization, Metabolic Health, and Muscle Loss

Healthy

United Kingdom
University College, London
Wellcome Trust

Unknown

A Phase I Clinical Trial of DARC

Ocular Hypertension | Glaucoma | Glaucoma, Suspect

United Kingdom
Imperial College London
Wellcome Trust

Completed

The Development of a Human Model of Respiratory Syncytial Virus Infection

Respiratory Syncytial Virus Infections | Respiratory Viral Infections

United Kingdom
University of Oxford
Wellcome Trust

Completed

A Study to Assess the Safety and Immunogenicity of a New Influenza Vaccine Candidate MVA-NP+M1 in Healthy Adults

Influenza

United Kingdom
University College, London
Wellcome Trust

Unknown

Differential Effects of Lipids on Cardiovascular Diseases: A CALIBER Study

ST Elevation Myocardial Infarction | Stable Angina | Unstable Angina | Non ST Elevation Myocardial Infarction | Myocardial Infarction Not Otherwise Specified

United Kingdom
University of Oxford
Wellcome Trust

Completed

A Study to Assess the Safety and Efficacy of a New Influenza Candidate Vaccine MVA-NP+M1 In Healthy Adults

Influenza

United Kingdom
University of Oxford
Wellcome Trust

Unknown

Immediate Versus Deferred Antiretroviral Therapy for HIV-Associated Tuberculous Meningitis

HIV Infections | Tuberculous Meningitis

Vietnam
Aga Khan University
Wellcome Trust

Unknown

Comparison of Screening Tools for Coronary Artery Disease

Cardiovascular Disease

Pakistan
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children

HIV Infections | Bacterial Infections | Pneumonia, Pneumocystis Carinii

United States, Puerto Rico
University of Oxford
Wellcome Trust

Recruiting

Simvastatin and Emotional Processing (OxSTEP) (OxSTEP)

Depression | Inflammation

United Kingdom
University of Oxford
Wellcome Trust

Terminated

Neurofeedback for Stroke Rehabilitation

Stroke

United Kingdom
Novartis Pharmaceuticals
Wellcome Trust

Completed

Study to Assess Safety, Tolerability and Phamacokinetics of KAE609 Administered Intravenously in Healthy Subjects

Malaria

Belgium
University of Oxford
Wellcome Trust

Completed

7-day Atorvastatin and Emotional Processing

Healthy

United Kingdom
University of Oxford
Wellcome Trust

Completed

The Clinical and Molecular Epidemiology of Streptococcus Agalactiae Colonisation on the Kenyan Coast (GBS)

Streptococcus Agalactiae (Streptococcus Group B)

Kenya

Clinical Trials Sponsored by Glaxo Wellcome

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