Clinical Trials Sponsored by GlaxoSmithKline

Total 4410 results

GlaxoSmithKline

Not yet recruiting

A Study for GSK3862995B in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

United Kingdom
Sociedad Española de Neumología y Cirugía Torácica

Not yet recruiting

Exacerbantes Study

COPD Exacerbation
ViiV Healthcare

Not yet recruiting

Long-term Follow-up of Long-acting Cabotegravir (CAB LA) for PrEP (Pre-exposure Prophylaxis) in Participants at Risk of Acquiring HIV (Human Immunodeficiency Virus) (PALISADE)

HIV Infections
GlaxoSmithKline

Not yet recruiting

A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup B Infection in Healthy Infants From 2 Months of Age

Meningitis, Meningococcal

Korea, Republic of
University College, London

Not yet recruiting

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB (PARADIGM4TB)

Pulmonary Tuberculosis
Alector Inc.

Recruiting

Continuation Study for Latozinemab

Neurodegenerative Diseases

United States, Canada
GlaxoSmithKline

Not yet recruiting

Dose Exploration Study of GSK4532990 in Participants With NASH or Suspected NASH (SKYLINE)

Non-alcoholic Fatty Liver Disease
GlaxoSmithKline

Not yet recruiting

Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease (PROGRESS-AD)

Alzheimer's Disease

United States, Australia, Finland, Spain, France, Korea, Republic of, Taiwan, Germany, Italy, Canada, Sweden, Argentina, Turkey, Norway, Netherlands and more
GlaxoSmithKline

Recruiting

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Preliminary Anticancer Activity of GSK4524101 Alone or With Niraparib in Participants With Solid Tumors

Neoplasms

United States, Canada
GlaxoSmithKline

Not yet recruiting

Concentration-QT Study of Paroxetine in Healthy Adults

Anxiety Disorders
GlaxoSmithKline

Not yet recruiting

Phase 2 Platform Study of Novel Immunotherapy Combinations as First-Line Treatment in Participants With PD-L1 Positive Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Neoplasms, Head and Neck

United States, Spain, Finland, Taiwan, Germany, Romania, Canada, Korea, Republic of, Portugal, Sweden, Turkey, Greece, Argentina, Italy, Poland and more
Spero Therapeutics

Not yet recruiting

A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (PIVOT-PO)

Urinary Tract Infection | Acute Pyelonephritis
GlaxoSmithKline

Not yet recruiting

A Study to Evaluate the Relative Bioavailability of Subcutaneous Bepirovirsen When Delivered From a Vial or Prefilled Syringe Fitted With a Safety Syringe Device in Healthy Adult Participants

Hepatitis B

United States
GlaxoSmithKline

Not yet recruiting

REIMAGINE - Real World EvaluatIon of Mepolizumab in Severe Asthma achievinG on Treatment clinIcal remissioN, a prospEctive Study (REIMAGINE)

Asthma
German Asthma Net e.V.

Recruiting

Register Schweres Asthma - German Asthma Net e.V.

Severe Asthma

Germany
GlaxoSmithKline

Recruiting

Immunogenicity, Reactogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Rotarix Porcine Circovirus (PCV)-Free Liquid Compared to Rotarix Liquid Given in 2-doses in Healthy Chinese Infants Starting at Age 6-16 Weeks

Gastroenteritis

China
Latin American Cooperative Oncology Group

Not yet recruiting

Molecular and Epidemiological Characteristics of Endometrial Cancer in Brazil (MADONNA)

Endometrial Cancer

Brazil
GlaxoSmithKline

Recruiting

A Dose Finding Study to Investigate the Safety and Effectiveness of GSK1070806 in Adult Participants With Moderate to Severe Atopic Dermatitis

Dermatitis, Atopic

Argentina, Japan, Korea, Republic of, Spain, United States, Bulgaria, Canada, China, Czechia, France, Germany, Greece, Italy, Mexico, Panama and more
GlaxoSmithKline

Not yet recruiting

A First Time in Human Study to Evaluate the Safety and Tolerability of GSK4381406 in Healthy Participants

Colitis, Ulcerative

United Kingdom
Medicines for Malaria Venture

Recruiting

Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum

Pathologic Processes | Infections | Systemic Inflammatory Response Syndrome | Inflammation | Vector Borne Diseases | Parasitic Diseases | Protozoan Infections | Malaria | Parasitemia | Malaria,Falciparum ...

Australia
GlaxoSmithKline

Recruiting

Safety and Immunogenicity of Different Formulations of Monovalent Influenza A/Astrakhan/3212/2020 Like (H5N8) Virus Vaccine With AS03 Adjuvant System in Medically Stable Adults

Influenza, Human

United States
GlaxoSmithKline

Recruiting

A Safety and Immune Response Study to Evaluate Varying Doses of an mRNA Vaccine Against Coronavirus Disease 2019 (COVID-19) in Healthy Adults

COVID-19

United States
Sunnybrook Health Sciences Centre

Recruiting

Alternative Dosing Of Niraparib To Decrease Dose Interruption In First Line Maintenance Treatment For Ovarian Cancer

Ovarian Cancer | Stage IV Ovarian Cancer | High Grade Ovarian Serous Adenocarcinoma | Stage III Ovarian Cancer

Canada
Pack Health

Recruiting

PRO and Wearable Data Insights From Individuals With R/R Multiple Myeloma

Multiple Myeloma | Relapsed Hematologic Malignancy

United States
University of L'Aquila

Recruiting

Herpes Zoster Hospitalizations in Italy

Herpes Zoster | Comorbidities and Coexisting Conditions

Italy
Massachusetts General Hospital

Not yet recruiting

Isatuximab, Bela Maf, Pom, and Dex in Relapsed/Refractory Multiple Myeloma (ISABELA)

Multiple Myeloma | Refractory Multiple Myeloma | Relapsed Cancer

United States
GlaxoSmithKline

Recruiting

A Study on the Immune Response and Safety of an RSV Vaccine When Given to Adults 50 Years of Age and Above Who Received Lung or Kidney Transplant and Are at an Increased Risk of Respiratory Syncytial Virus Lower Respiratory Tract Disease and Compared to Healthy Adults 50 Years of Age and Above (RSV OA=ADJ-023)

Respiratory Syncytial Virus Infections

United States, Canada, Japan, Australia, Germany, Italy, Korea, Republic of, Spain
ViiV Healthcare

Recruiting

A Study to Evaluate the Efficacy, Safety, Participant Choice and Preference of an Oral Once-daily Regimen or a Long-acting Injectable Regimen Every Two Months for Treatment of Human Immunodeficiency Virus (HIV-1) in Adults Who Have Not Previously Taken Antiretroviral Therapy (VOLITION)

HIV Infections

United States
GlaxoSmithKline

Not yet recruiting

A Study of Belimumab in Chinese Pediatric Participants With Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Institute for Clinical Effectiveness, Japan

Recruiting

Effect of Respiratory Virus Infection on EmeRgencY Admission Study (EVERY Study) (EVERY)

Acute Disease | Respiratory Syncytial Virus (RSV) | Respiratory Viral Infection

Japan
Johns Hopkins University

Recruiting

The Role of IL5 in Epithelial Cell Integrity

Chronic Rhinosinusitis (Diagnosis) | Chronic Rhinosinusitis With Nasal Polyps

United States
University of Sao Paulo General Hospital

Recruiting

Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases (RZVRheum)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Systemic Sclerosis | Juvenile Idiopathic Arthritis | Sjogren's Syndrome | Spondylitis, Ankylosing | Spondyloarthritis | Behçet Disease | Idiopathic Inflammatory Myopathies | Vasculitis, Systemic ...

Brazil
GlaxoSmithKline

Recruiting

A Study of the Efficiency And Safety Study of Belimumab Compared To Placebo In Adults With Systemic Sclerosis Associated Interstitial Lung Disease (BLISSc-ILD)

Scleroderma, Systemic | Systemic Sclerosis Associated Interstitial Lung Disease

United States, Australia, France, Italy, Japan, Spain, Belgium, Greece, Korea, Republic of, China, Mexico, United Kingdom, Finland, Israel, Germany and more
Latin American Cooperative Oncology Group

Recruiting

A Collaborative Trial of Niraparib to Evaluate Patients With Ovarian Cancer in the Expanded Access Program in Latin America (CONOR)

Ovarian Cancer

Argentina, Brazil
GlaxoSmithKline

Recruiting

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer (AZUR-2)

Colonic Neoplasms | Neoplasms, Colon

Canada, United States, Argentina, Australia, Belgium, Brazil, Finland, France, Germany, Greece, Italy, Japan, Korea, Republic of, Mexico, Netherlands and more
Centre Leon Berard

Recruiting

PREventing Second Cancers With DOSTARlimab (PREDOSTAR)

Recurrent Cancer | Second Cancer | Primary Cancer

France
GlaxoSmithKline

Recruiting

A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic Pain (NEPTUNE-17)

Pain

United States, Germany, Japan, Spain, Canada, China, United Kingdom, South Africa, Korea, Republic of, France, Poland, Turkey
GlaxoSmithKline

Recruiting

A Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis Pain (MARS-17)

Pain

France, Japan, Spain, China, Korea, Republic of, United States, Argentina, Canada, Germany, South Africa, Australia, Mexico, United Kingdom
GlaxoSmithKline

Recruiting

A Study to Assess the Safety and Immune Response of a Vaccine Against Influenza in Healthy Younger and Older Adults

Influenza, Human

United States, Canada, South Africa, Belgium
M.D. Anderson Cancer Center

Recruiting

Phase I Trial Testing the Safety and Tolerability of Chemoradiation Followed by Chemotherapy + Dostarlimab for Stage IIIC, Node Positive, Endometrial Cancer

Endometrial Cancer

United States
GlaxoSmithKline

Not yet recruiting

Safety of Herpes Zoster Subunit (HZ/su) Vaccine During Pregnancy in Adult Women With Immunocompromised Conditions

Herpes Zoster
University of Chicago

Recruiting

Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma

Multiple Myeloma | Relapse Multiple Myeloma

United States
Grupo Español de Tratamiento de Tumores de Cabeza...

Recruiting

Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma (RADIAN)

Head and Neck Squamous Cell Carcinoma

Spain
University of Colorado, Denver

Not yet recruiting

Shingrix In Recipients of Allogeneic Transplants (Allo)

Stem Cell Transplant | Bone Marrow Transplant

United States
University of Minho

Not yet recruiting

Exploring Clinical Predictors of COPD Exacerbation in a Community Cohort (EPISODE)

COPD Exacerbation
GlaxoSmithKline

Recruiting

A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

Asthma

United States
GlaxoSmithKline

Recruiting

A Study of Dostarlimab in Untreated dMMR/MSI-H Locally Advanced Rectal Cancer (AZUR-1)

Neoplasms, Rectal

United States, France, Italy, Japan, Spain, United Kingdom, Germany, Korea, Republic of, Canada, Netherlands
The Christie NHS Foundation Trust

Recruiting

The Use and Development of Patient Reported Outcome Measures (PROMs) in the Adoptive Cell Therapy (ACT) Setting

Cancer

United Kingdom
ETOP IBCSG Partners Foundation

Not yet recruiting

Niraparib Added to Anti-PD-L1 Antibody Maintenance in SLFN11-positive, Extensive-disease SCLC (RAISE)

SCLC,Extensive Stage | SLFN11-positive

Switzerland, Spain, France, Italy
GlaxoSmithKline

Not yet recruiting

A Study to Investigate the Safety and Efficacy of Belantamab for the Treatment of Multiple Myeloma When Used as Monotherapy and in Combination Treatments (DREAMM-20)

Multiple Myeloma

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