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Clinical Trials Sponsored by GlaxoSmithKline

Total 4572 results

NCT04557371

Not yet recruiting

A Study to Assess the Local Cutaneous and Ocular Tolerance of Three Developmental Facial Skin-care Formulations.

Conditions: Skin Care
NCT04551989

Not yet recruiting

Mepolizumab Long-term Study to Assess Real World Safety and Effectiveness of Eosinophilic Granulomatosis With Polyangiitis (EGPA) in Japan

Conditions: Churg-Strauss Syndrome
NCT04549363

Not yet recruiting

Characterization of Corneal Epithelial Changes in Participants Treated With Belantamab Mafodotin

Conditions: Multiple Myeloma
NCT04544956

Not yet recruiting

A Mechanistic Study of GSK3228836 With Fine Needle Aspiration (FNA) in Participants With Chronic Hepatitis B

Conditions: Hepatitis B
NCT04544995

Not yet recruiting

Dose Escalation and Cohort Expansion Study of Niraparib and Dostarlimab in Pediatric Participants With Solid Tumors

Conditions: Neoplasms
NCT04545060

Recruiting

VIR-7831 for the Early Treatment of COVID-19 in Outpatients

Conditions: Covid19
NCT04537208

Recruiting

Study of Recombinant Protein Vaccine Formulations Against COVID-19 in Healthy Adults 18 Years of Age and Older

Conditions: COVID-19 (Healthy Volunteers)
NCT04535037

Not yet recruiting

A Study to Evaluate Immunogenicity and Safety of GlaxoSmithKline (GSK)'s Infanrix Hexa Vaccine (DTPa-HBV-IPV/Hib) Versus MCM Vaccine BV's Vaxelis Vaccine (DTaP5-HBV-IPV-Hib) in Healthy Infants and Toddlers

Conditions: Diphtheria
NCT04526509

Not yet recruiting

Investigation of Autologous Enhanced T Cells in Advanced Tumors

Conditions: Neoplasms
NCT04512521

Recruiting

Functional Lung MRI for Early Treatment Response Assessment for Patients With Eosinophilic Asthma

Conditions: Asthma; Eosinophilic
NCT04504435

Not yet recruiting

Safety, Tolerability and Pharmacokinetics (PK) Investigation of GSK3494245 in Healthy Participants

Conditions: Leishmaniasis
NCT04502602

Recruiting

Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer

Conditions: Advanced Solid Tumor; Ovarian Cancer
NCT04502693

Recruiting

Study to Assess Effectiveness of GlaxoSmithKline's (GSK's) Meningococcal Group B and Combined ABCWY Vaccines in Healthy Adolescents and Young Adults.

Conditions: Infections, Meningococcal
NCT04494412

Not yet recruiting

An Intravenous (IV) Zanamivir Pharmacokinetics (PK) Study in Hospitalized Neonates and Infants With Influenza Infection

Conditions: Influenza, Human
NCT04493931

Recruiting

Drug-drug Interaction Study of Gepotidacin

Conditions: Bacterial Infections; Infections, Bacterial
NCT04488770

Recruiting

Safety, Tolerability and Pharmacokinetic Investigation of GSK3882347 in Healthy Participants.

Conditions: Urinary Tract Infections
NCT04484623

Not yet recruiting

Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma

Conditions: Multiple Myeloma
NCT04481113

Not yet recruiting

Abemaciclib and Niraparib Before Surgery for the Treatment of Hormone Receptor Positive HER2 Negative Breast Cancer

Conditions: Anatomic Stage I Breast Cancer AJCC v8; Anatomic Stage IA Breast Cancer AJCC v8; Anatomic Stage IB Breast Cancer AJCC v8; Anatomic Stage II Breast Cancer AJCC v8; Anatomic Stage IIA Breast Cancer AJCC v8; Anatomic Stage IIB Breast Cancer AJCC v8; Anatomic Stage IIIA Breast Cancer AJCC v8; Hormone Receptor Positive Breast Carcinoma; Invasive Breast Carcinoma; Multifocal Breast Carcinoma; Prognostic Stage I Breast Cancer AJCC v8; Prognostic Stage IA Breast Cancer AJCC v8; Prognostic Stage IB Breast Cancer AJCC v8; Prognostic Stage II Breast Cancer AJCC v8; Prognostic Stage IIA Breast Cancer AJCC v8; Prognostic Stage IIB Breast Cancer AJCC v8; Prognostic Stage IIIA Breast Cancer AJCC v8; Prognostic Stage IIIB Breast Cancer AJCC v8; Unilateral Breast Carcinoma; HER2 Negative Breast Carcinoma
NCT04475939

Not yet recruiting

Placebo-controlled Study Comparing Niraparib Plus Pembrolizumab Versus Placebo and Pembrolizumab as Maintenance Therapy

Conditions: Lung Cancer, Non-Small Cell
NCT04472897

Not yet recruiting

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of GSK2556286 in Healthy Adult Participants

Conditions: Tuberculosis
NCT04473521

Not yet recruiting

A Clinical Study to Assess Force Required to Dislodge Upper Denture With and Without Use of a Novel Denture Adhesive

Conditions: Denture Retention
NCT04449029

Recruiting

A Study of GSK3228836 in Participants With Chronic Hepatitis B (CHB)

Conditions: Hepatitis B
NCT04449419

Recruiting

Mitoquines in COPD

Conditions: COPD Exacerbation
NCT04447053

Not yet recruiting

Sequential Belimumab and T-cell Based Therapy in SLE

Conditions: Systemic Lupus Erythematosus
NCT04446351

Recruiting

Study of the Safety and Effectiveness of GSK6097608 in Participants With Advanced Solid Tumors

Conditions: Neoplasms
NCT04428333

Recruiting

Study of GSK3359609 With Pembrolizumab and 5-fluorouracil (5-FU)-Platinum Chemotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Conditions: Neoplasms, Head and Neck
NCT04420221

Recruiting

Safety, Immunogenicity and Efficacy of GSK S. Aureus Candidate Vaccine (GSK3878858A) When Administered to Healthy Adults (Dose-escalation) and to Adults 18 to 50 Years of Age With a Recent S. Aureus Skin and Soft Tissue Infection (SSTI)

Conditions: Infections, Soft Tissue
NCT04398680

Not yet recruiting

A Study of Belantamab Mafodotin (GSK2857916) in Multiple Myeloma Participants With Normal and Impaired Hepatic Function

Conditions: Multiple Myeloma
NCT04398745

Not yet recruiting

A Study of Belantamab Mafodotin (GSK2857916) in Multiple Myeloma Participants With Normal and Impaired Renal Function

Conditions: Multiple Myeloma
NCT04376684

Recruiting

Investigating Otilimab in Patients With Severe Pulmonary COVID-19 Related Disease

Conditions: Severe Acute Respiratory Syndrome
NCT04371380

Not yet recruiting

Pharmacokinetic Study of Cabotegravir and Rilpivirine Long-acting Intramuscular Injections in Healthy Adult Participants

Conditions: HIV Infections
NCT04369495

Not yet recruiting

BAFF Levels and Lupus Nephritis (LN)

Conditions: Lupus Nephritis
NCT04366349

Recruiting

A Study to Evaluate the Safety and Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK3772847 in Healthy Participants

Conditions: Healthy Volunteers; Asthma
NCT04349280

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Bintrafusp Alfa (M7824) Monotherapy in Metastatic or Locally Advanced Urothelial Cancer

Conditions: Neoplasms
NCT04341181

Not yet recruiting

ProTarget - A Danish Nationwide Clinical Trial on Targeted Cancer Treatment Based on Genomic Profiling

Conditions: Cancer; Tumors; Neoplasms; Neoplasia
NCT04333147

Recruiting

Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA)

Conditions: Arthritis, Rheumatoid
NCT04318535

Completed

Bioequivalence (BE) Study of Test Griseofulvin 500 Milligram (mg) Tablets Versus Reference and Dose Proportionality Study of Test Griseofulvin 250 mg and 500 mg Tablets Under Fed Conditions

Conditions: Antifungal Agents
NCT04318548

Recruiting

Study to Assess the Immunogenicity and Safety of GSK's Meningococcal Group B Vaccine When Administered Concomitantly With GSK's Meningococcal MenACWY Conjugate Vaccine in Healthy Subjects of 16-18 Years of Age

Conditions: Infections, Meningococcal
NCT04316585

Not yet recruiting

A Study to Evaluate the Benefit and Safety of GSK2982772 in Moderate to Severe Psoriasis Participants

Conditions: Psoriasis
NCT04311463

Not yet recruiting

Bioequivalence Study of Paroxetine and PAXIL Tablets Under Fasting Conditions in Healthy Mexican Participants

Conditions: Anxiety Disorders
NCT04305678

Not yet recruiting

Mepolizumab for Eosinophilic Fasciitis

Conditions: Eosinophilic Fasciitis
NCT04295733

Recruiting

Safety, Tolerability and Immunogenicity of 4CMenB Vaccine(2 Doses) in Adults With an Immunodeficiency

Conditions: Acquired Immunodeficiency
NCT04292912

Recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK2798745 in Subjects With Diabetic Macular Edema (DME)

Conditions: Macular Edema
NCT04290624

Not yet recruiting

A Clinical Study to Evaluate the Efficacy of a Range of Dental/Denture Products for Improved Oral Health in Partial Denture Wearers

Conditions: Gingivitis
NCT04276233

Not yet recruiting

Phase 4 Study of Mepolizumab 100 Milligram (mg) Subcutaneous (SC) in Indian Subjects Aged >=18 Years With Severe Eosinophilic Asthma Requiring Maintenance Oral Corticosteroids

Conditions: Asthma
NCT04274023

Not yet recruiting

Study on TSR-042 in Advanced Clear Cell Sarcoma

Conditions: Sarcoma, Clear Cell
NCT04260282

Not yet recruiting

Microbiome and Exacerbations in Neutrophilic Asthma

Conditions: Asthma; Microbiome; Exacerbation
NCT04246047

Recruiting

Evaluation of Efficacy and Safety of Belantamab Mafodotin, Bortezomib and Dexamethasone Versus Daratumumab, Bortezomib and Dexamethasone in Participants With Relapsed/Refractory Multiple Myeloma

Conditions: Multiple Myeloma
NCT04240106

Recruiting

Niraparib Plus Aromatase Inhibitors for Luminal-like(HER2-negative,ER-positive) and gBRCA or HDR-positive Metastatic Breast Cancer(LUZERN)

Conditions: Breast Cancer; Breast Cancer Metastatic
NCT04237896

Not yet recruiting

Compliance With Clinical Guidelines and Effect on Patient Outcome of Treatment of Hospitalised Exacerbations of COPD

Conditions: Pulmonary Disease, Chronic Obstructive

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Clinical Trials Sponsored by GlaxoSmithKline