Clinical Trials Sponsored by Grupo Espanol de Investigacion en Sarcomas

Total 101 results

Grupo Espanol de Investigacion en Sarcomas

Recruiting

Multicohort Trial of Trabectedin and Low-dose Radiation Therapy in Advanced/Metastatic Sarcomas (SYNERGIAS)

Soft Tissue Sarcoma | Bone Tumors | Small Round-cell Sarcomas

Spain
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas (ImmunoSarc)

Soft Tissue Sarcoma | Bone Sarcoma

Spain, United Kingdom, Italy
Grupo Espanol de Investigacion en Sarcomas

Completed

ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

Osteosarcoma

Spain
Grupo Espanol de Investigacion en Sarcomas

Terminated

Doxorubicin vs. Trabectedin Plus Doxorubicin in Non Operable and/or Metastatic STS

Sarcoma

Spain
Grupo Espanol de Investigacion en Sarcomas

Unknown

Phase I-II Trial of Sorafenib in Combination With Ifosfamide in Soft Tissue Sarcoma

Soft Tissue Sarcoma

Spain
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Phase I/II of LB-100 Plus Doxorubicin vs. Doxorubicin Alone in First Line of Advanced Soft Tissue Sarcomas (Enhancer)

Advanced Soft-tissue Sarcoma

Spain
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination With Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor (PRIME)

Advanced Solid Tumor | Advanced Soft-tissue Sarcoma | Advanced L-sarcomas | Other Advanced Sarcomas | Localized Soft-tissue Sarcoma

Spain
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma and Osteosarcoma (SeliSarc)

Sarcoma,Soft Tissue

Spain
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK ((SELNET))

Gastrointestinal Stromal Tumors | Soft-tissue Sarcoma | Bone Sarcoma

France, Spain, Argentina, Costa Rica, Brazil, Italy, Mexico, Peru
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression. (PalboSarc)

Osteosarcoma | Chordoma | Soft-tissue Sarcoma

Spain
Grupo Espanol de Investigacion en Sarcomas

Completed

Trial of Nab-paclitaxel in Patients With Desmoid Tumors and Multiply Relapsed/Refractory Desmoplastic Small Round Cell Tumors and Ewing Sarcoma (ABRADES)

Sarcoma | Sarcoma, Ewing | Desmoid | Tumor, Desmoplastic Small Round Cell, Adult | Tumor, Desmoplastic Small Round Cell, Childhood

Spain
Grupo Espanol de Investigacion en Sarcomas

Completed

Study of Intensive Chemotherapy, Surgery and Radiotherapy to Treat Ewing's Sarcoma in Children and Young Adults

Ewing's Sarcoma

Spain
Grupo Espanol de Investigacion en Sarcomas

Completed

Gemcitabine Plus Rapamycin Versus Gemcitabine to Treat Advanced Soft Tissue Sarcoma

Advanced Soft Tissue Sarcoma

Spain
Grupo Espanol de Investigacion en Sarcomas

Completed

Trial of Pazopanib in Patients With Solitary Fibrous Tumor and Extraskeletal Myxoid Chondrosarcoma

Extraskeletal Myxoid Chondrosarcoma | Solitary Fibrous Tumor

Spain
Grupo Espanol de Investigacion en Sarcomas

Active, not recruiting

Olaratumab Plus Trabectedin in Advanced Soft-tissue Sarcoma Patients Soft-tissue Sarcoma Patients (OLATRASTS)

Sarcoma, Soft Tissue

Spain
Grupo Espanol de Investigacion en Sarcomas

Active, not recruiting

Selinexor as Single Agent and With Imatinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors (SeliGIST) (SeliGIST)

Drug Use | GIST | Drug Toxicity | Metastatic Adult Soft Tissue Sarcoma | Maximum Tolerated Dose

Spain
Grupo Espanol de Investigacion en Sarcomas

Completed

Neoadyuvant High-dose of Ifosfamide and Concurrent Radiotherapy in Soft Tissue Sarcoma

Soft Tissue Sarcoma

Spain
Grupo Espanol de Investigacion en Sarcomas
Bayer

Completed

Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST (REGISTRI)

Gastrointestinal Stromal Tumors

Spain, France, Italy
Grupo Espanol de Investigacion en Sarcomas
GlaxoSmithKline

Completed

Activity and Tolerability of Pazopanib in Advanced and/or Metastatic Liposarcoma. A Phase II Clinical Trial

Advanced and / or Metastatic Liposarcoma

Spain, Germany
Italian Sarcoma Group
French Sarcoma Group; Grupo Espanol de Investigacion en Sarcomas

Active, not recruiting

Localized High-Risk Soft Tissue Sarcomas Of The Extremities And Trunk Wall In Adults: An Integrating Approach Comprising Standard Vs Histotype-Tailored Neoadjuvant Chemotherapy

Localized High-risk Soft Tissue Sarcomas of the Extremities and Trunk Wall in Adults

Spain, Italy
Grupo Espanol de Investigacion en Sarcomas
Centre Leon Berard; Italian Sarcoma Group

Recruiting

Trabectedin Plus Radiotherapy in Soft Tissue Sarcoma Patients (TRASTS)

Sarcoma, Soft Tissue | Leiomyosarcoma | Liposarcoma | Liposarcoma, Myxoid | Pleomorphic Liposarcoma

France, Spain, Italy
Grupo Español de Investigación en Neurooncología

Completed

Study of Sunitinib Before and During Radiotherapy in Newly Diagnosed Biopsy-only Glioblastoma Patients

Glioblastoma

Spain
Grupo Español de Investigación en Neurooncología

Unknown

Metronomic Temozolamide in Patients With Recurrent Glioblastoma

Glioblastoma
Grupo Español de Investigación en Neurooncología

Completed

Glasdegib (PF-04449913) With Temozolomide Newly Diagnosed Glioblastoma (GEINOGLAS)

Glioblastoma

Spain
Grupo Español de Investigación en Neurooncología

Completed

Temozolomide 12 Cycles Versus 6 Cycles of Standard First-line Treatment in Patients With Glioblastoma.

Glioblastoma

Spain
Grupo Español de Investigación en Neurooncología

Completed

Neo-adjuvant Treatment With Temozolomide and Bevacizumab Previous to Temozolomide Plus Radiation Plus Bevacizumab Therapy in Unresectable Glioblastoma

Glioblastomas

Spain
Grupo Español de Investigación en Neurooncología
Pfizer

Completed

Study to Evaluate Safety and Activity of Crizotinib With Temozolomide and Radiotherapy in Newly Diagnosed Glioblastoma

Glioblastoma Multiforme (Grade IV) of Cerebellum

Spain
Grupo Español de Investigación en Neurooncología
Pfizer

Completed

Safety and Efficacy of PF-299804 (Dacomitinib), a Pan-HER Irreversible Inhibitor, in Patients With Recurrent Glioblastoma With EGFR Amplification or Presence of EGFRvIII Mutation. A Phase II CT.

Glioblastoma | Brain Tumor, Recurrent

Spain
Grupo Español de Investigación en Neurooncología
Pfizer

Completed

Safety and Efficacy of PD0332991 (Palbociclib), a Cyclin-dependent Kinase 4 and 6 Inhibitor, in Patients With Oligodendroglioma or Recurrent Oligoastrocytoma Anaplastic With the Activity of the Protein RB Preserved

Oligoastrocytoma | Oligodendroglioma

Spain
Grupo Español de Investigación en Cáncer de Ovario

Recruiting

DOstarlimab in Patients With Recurrent or dMMR/MSI-H Endometrial Cancer (DORA)

Endometrial Cancer

Spain
Grupo Español de Investigación en Cáncer de Ovario

Completed

Retrospective Multicenter Study of Elderly Patients With Ovarian Cancer Treated With Trabectedin and PLD

Ovarian Cancer

Spain
Grupo Español de Investigación en Cáncer de Ovario

Completed

Niraparib as Maintenance Therapy in Patients With Platinum Sensitive Recurrent Ovarian Cancer

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

Spain
Grupo Español de Investigación en Cáncer de Ovario

Completed

Clinical Trial Investigating Pazopanib in Patients With Platinum-resistant Advanced Ovarian Cancer

Platinum-resistant Advanced Ovarian Cancer

Spain
European Organisation for Research and Treatment...
UNICANCER; Grupo Espanol de Investigacion en Sarcomas; Italian Sarcoma Group

Completed

Imatinib Mesylate or Observation Only in Treating Patients Who Have Undergone Surgery for Localized Gastrointestinal Stromal Tumor

Gastrointestinal Stromal Tumor

France, Australia, United Kingdom, Germany, Denmark, Spain
Grupo Español de Investigación en Cáncer de Ovario
PharmaMar

Completed

Retrospective Study to Analyze the Efficacy and Safety of Trabectedin and Pegylated Liposomal Doxorubicin (PLD ) in the Treatment of Patients With Platinum-sensitive Recurrent Ovarian Cancer (ROC), According to SmPC (RETRO-ROC)

Ovarian Epithelial Cancer Recurrent
Grupo Español de Investigación en Cáncer de Ovario
AstraZeneca

Completed

Resistant Ovarian Cancer, Olaparib and Liposomal Doxorubicin (ROLANDO)

Advanced Ovarian Cancer

Spain
Grupo Español de Investigación en Cáncer de Ovario
Neovii Biotech

Completed

Catumaxomab as a Consolidation Therapy in Patients With Ovarian Cancer in Second or Third Clinical Disease Remission

Ovarian Cancer

Spain
Grupo Español de Investigación en Cáncer de Ovario
Roche Pharma AG

Terminated

Neoadjuvant Therapy in Advanced Ovarian Cancer With Avastin (NOVA)

Cancer, Ovarian

Spain
Grupo Español de Investigación en Cáncer de Ovario
Clovis Oncology, Inc.

Completed

Analysis of the Clinical Experience With Rucaparib in the Rucaparib Access Program (RAP) in Spain - A GEICO Study

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

Spain
Grupo Español de Investigación en Cáncer de Ovario
AstraZeneca; Apices Soluciones S.L.

Completed

Olaparib After Response to Trabectedin-pegylated Liposomal Doxorubicin in Recurrent Ovarian Carcinoma

Ovarian Cancer

Spain
Grupo Español de Investigación en Cáncer de Ovario
Apices Soluciones S.L.; TESARO/GSK

Active, not recruiting

TSR-042 as Maintenance Therapy for Patients With High-risk Locally Advanced Cervical Cancer After Chemo-radiation (ATOMICC) (ATOMICC)

Cervical Cancer | Advanced Cancer

Spain, Turkey
Grupo de Investigación Clínica en Oncología Radioterapia

Completed

OPTimizing Irradiation Through Molecular Assessment of Lymph Node (OPTIMAL) (OPTIMAL)

Breast Cancer

Spain, Portugal, Italy
Grupo de Investigación Clínica en Oncología Radioterapia

Completed

Erlotinib,Radiation and Cisplatin in Patients With Complete Resected Squamous Cell Carcinoma of the Head and Neck

Squamous Cell Carcinoma of the Head and Neck

Spain
Grupo de Investigación Clínica en Oncología Radioterapia

Completed

N2 Lung Cancer Project: Neoadjuvant Treatment Followed Surgery Versus Chemoradiation

Chemoradiation | Surgery | Survival | Non-small-Cell Lung Carcinoma | Stage IIIA-N2

Spain
Grupo de Investigación Clínica en Oncología Radioterapia

Completed

Intranasal Transmucosal Fentanyl Pectin for Breakthrough Cancer Pain in Radiation-induced Oropharyngeal Mucositis (CP073)

Head and Neck Cancer | Chemotherapy | Mucositis | Breakthrough Pain | Radiotherapy

Spain
Grupo de Investigación Clínica en Oncología Radioterapia

Recruiting

Multicenter Study of Hypofractionated Postoperative Radiotherapy in Patients Diagnosed With Prostate Carcinoma

Prostate Cancer

Spain
Grupo de Investigación Clínica en Oncología Radioterapia

Completed

Phase II Study of SBRT as Treatment for Oligometastases in Prostate Cancer

Oligometastatic Prostate Cancer

Spain
Grupo de Investigación Clínica en Oncología Radioterapia

Terminated

OPTimizing Irradiation Through Molecular Assesment of Lymph Node After Primary Systemic Treatment (OPTIMALIIa)

Breast Cancer

Spain
Grupo de Investigación Clínica en Oncología Radioterapia

Completed

Memory Preservation of Prophylactic Cranial Irradiation With Hippocampal Avoidance (PREMER-TRIAL)

Small Cell Lung Carcinoma

Spain
Grupo de Investigación Clínica en Oncología Radioterapia

Unknown

Dose-escalation Trial of Preoperative Radiotherapy and Concurrent Chemotherapy in Locally Advanced Rectal Cancer

Locally Advanced Rectal Cancer

Spain

Clinical Trials Sponsored by Grupo Espanol de Investigacion en Sarcomas

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