Clinical Trials Sponsored by HIV Prevention Trials Network

Total 128 results

HIV Prevention Trials Network

Completed

Feasibility and Acceptability Study of an Individual-Level Behavioral Intervention for Individuals With Acute and Early HIV-Infection

Acute HIV Infection

Malawi
HIV Prevention Trials Network

Completed

Dose-Proportionality and Intra-Individual Variability of Intracellular TFV-DP and FTC-TP in Healthy Volunteers (HPTN066)

HIV

United States
HIV Prevention Trials Network

Completed

Preparing for International Prevention Trials Involving HIV-Infected Individuals in Care Settings (HPTN063)

HIV

Brazil, Thailand, Zambia
HIV Prevention Trials Network

Completed

A Comparison of Different Community Models of ART Delivery Amongst Stable HIV+ Patients in Two Urban Settings in Zambia

HIV Infections

Zambia
HIV Prevention Trials Network

Completed

The ADAPT Study: Use of Emtricitabine and Tenofovir Disoproxil Fumarate for Pre-Exposure Prophylaxis (PrEP) (ADAPT)

HIV Infections

United States, South Africa, Thailand
HIV Prevention Trials Network

Completed

HPTN 073 Black Men Who Have Sex With Men (MSM) Pre-Exposure Prophylaxis (PrEP)

HIV

United States
Gilead Sciences
HIV Prevention Trials Network

Recruiting

Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN-102) (PURPOSE 3)

Pre-Exposure Prophylaxis of HIV Infection

United States
HIV Prevention Trials Network
Gilead Sciences

Active, not recruiting

Pre-Exposure Prophylaxis for Transgender Women in the US and South America

HIV Prevention

United States, Brazil
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to Vaccination With 2 Experimental HIV Vaccines in Healthy Adults (HVTN 097)

HIV Infection

South Africa
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); HIV Prevention...

Completed

Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19

COVID-19 | SARS-CoV-2

United States, Zimbabwe, Malawi, Peru, South Africa, Zambia
HIV Vaccine Trials Network

Completed

An Observational Study of Long-term Outcomes of HIV-1 Infection in Persons Who Become HIV-1 Infected After Enrollment in HIV-1 Vaccine Trials

HIV Infections

United States, Dominican Republic, Haiti, Peru, Puerto Rico, South Africa
HIV Vaccine Trials Network

Completed

Evaluating the Safety and Priming Response of an HIV Vaccine Regimen in Healthy, HIV-Uninfected Adults

HIV Infections

Switzerland
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network; HIV Prevention Trials Network

Completed

Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of the Monoclonal Antibody PGT121.414.LS Administered Alone and in Combination With VRC07-523LS Via Intravenous or Subcutaneous Infusions in Healthy, HIV-uninfected Adult Participants

HIV Infections

United States
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); AIDS Clinical... and other collaborators

Recruiting

Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 703/HPTN 081 AMP Study

HIV Infection

Malawi, Botswana, South Africa, Zimbabwe
HIV Vaccine Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); AIDS Clinical... and other collaborators

Active, not recruiting

Analytical Treatment Interruption (ATI) to Assess the Immune System's Ability to Control HIV in Participants Who Became HIV-infected During the HVTN 704/HPTN 085 AMP Study

HIV Infection

United States, Peru, Brazil
CIHR Canadian HIV Trials Network

Completed

Chloroquine as a Modulator of T Cell Immune Activation

HIV

Canada
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

The Women's HIV SeroIncidence Study (ISIS)

HIV Infections

United States
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Enhancing Recruitment, Linkage to Care and Treatment for HIV-Infected MSM in the United States

HIV

United States
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

HIV Incidence and Participation Retention in Pune, India

HIV Infections | HIV Seronegativity

India
National Institute of Allergy and Infectious Diseases...
HIV Prevention Trials Network

Completed

Preventing Sexual Transmission of HIV With Anti-HIV Drugs

HIV Infections

Brazil, Malawi, India, Botswana, Kenya, South Africa, Zimbabwe, United States, Thailand
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Evaluating Methods to Increase HIV Testing, Access to HIV Care, and HIV Prevention Strategies

HIV Infection

United States
McMaster University
CIHR Canadian HIV Trials Network

Completed

Estrogen, Probiotics and Vaginal Health to Prevent HIV Infection in ACB Women

HIV-1-infection | Bacterial Vaginoses

Canada
University Health Network, Toronto
CIHR Canadian HIV Trials Network

Terminated

Probiotic Visbiome for Inflammation and Translocation in HIV Ι (PROOV IT I)

HIV-1 Infection

Canada
University Health Network, Toronto
CIHR Canadian HIV Trials Network

Unknown

Probiotic Visbiome for Inflammation and Translocation in HIV II (PROOV IT II)

HIV-1 Infection

Canada
University Health Network, Toronto
CIHR Canadian HIV Trials Network

Completed

Can Valacyclovir Delay the Need for Initiation of Human Immunodeficiency Virus (HIV) Treatment in HIV-infected Individuals? (VALIDATE)

HIV Infections | HIV Infection | Herpes Simplex Type II

Canada, United Kingdom, Argentina, Brazil
Ottawa Hospital Research Institute
Ontario HIV Treatment Network; CIHR Canadian HIV Trials Network

Completed

Micronutrients and Antioxidants in HIV Infection (MAINTAIN)

HIV Infection

Canada
National Institute of Allergy and Infectious Diseases...
AIDS Clinical Trials Group; HIV Prevention Trials Network

Completed

Evaluating the Safety and Tolerability of Antiretroviral Drug Regimens Used as Pre-Exposure Prophylaxis to Prevent HIV Infection in At-Risk Men Who Have Sex With Men and in At-Risk Women

HIV Infection

United States, Puerto Rico
Unity Health Toronto
CIHR Canadian HIV Trials Network

Completed

Bone Antiresorptive Therapy With Antiretroviral Initiation (BATARI) Pilot Trial (BATARI)

HIV

Canada
Merck Sharp & Dohme LLC
HIV Vaccine Trials Network

Terminated

Investigation of V520 in an HIV Vaccine Proof-of-Concept Study (V520-023)

HIV Infections | AIDS
Yaounde Central Hospital
CIHR Canadian HIV Trials Network

Completed

Cameroon Mobile Phone SMS Trial (CAMPS)

HIV | Adherence

Cameroon
University of California, Los Angeles
National Institute of Mental Health (NIMH); HIV Prevention Trials Network

Completed

Community Mobilization, Mobile Testing, Same-Day Results, and Post-Test Support for HIV in Sub-Saharan Africa and Thailand

HIV Infections

South Africa, Tanzania, Thailand, Zimbabwe
Mount Sinai Hospital, Canada
CIHR Canadian HIV Trials Network

Unknown

Progesterone Supplementation for HIV-positive Pregnant Women on Anti-Retrovirals (ProSPAR)

HIV-1 Infection

Canada
University of British Columbia
CIHR Canadian HIV Trials Network

Suspended

3TC or No 3TC for HIV With 3TC Resistance

HIV Infections

Canada
Ottawa Hospital Research Institute
CIHR Canadian HIV Trials Network

Withdrawn

Improving Fibrosis Outcomes With Metformin

HIV Infection | Hepatitis C

Canada
HIV Vaccine Trials Network
South Africa AIDS Vaccine Initiative

Completed

Safety of and Immune Response to a DNA HIV Vaccine Boosted With a Modified Vaccinia HIV Vaccine and Protein HIV Vaccine in Healthy Adults

HIV Seronegativity | HIV Preventive Vaccine

South Africa
Ottawa Hospital Research Institute
CIHR Canadian HIV Trials Network

Terminated

Penicillin Therapeutic Drug Monitoring in the Treatment of Infectious Syphilis.

Syphilis | Primary Syphilis | Secondary Syphilis | Early-Latent Syphilis

Canada
University of California, San Francisco
National Cancer Institute (NCI); US-Latin American-Caribbean HIV/HPV-Cancer...

Recruiting

Screening Algorithms for Cervical and Anal High-Grade Squamous Intraepithelial Lesions in People With HIV in Mexico and Puerto Rico (CAMPO-101)

HIV Infection | High Grade Cervical Intraepithelial Neoplasia | AIDS-Related Anal Carcinoma | AIDS-Related Cervical Carcinoma | High Grade Anal Intraepithelial Neoplasia

Puerto Rico, Mexico
University of British Columbia
AstraZeneca; CIHR Canadian HIV Trials Network

Terminated

Effectiveness of Rosuvastatin at Preventing the Progression of Atherosclerosis in HIV Positive Patients

HIV Infections | Atherosclerosis

Canada
Unity Health Toronto
Gilead Sciences; CIHR Canadian HIV Trials Network

Terminated

Virtual PrEP: Rendering PrEP Delivery More Efficient (VPrEP)

HIV Infections

Canada
University of British Columbia
GlaxoSmithKline; CIHR Canadian HIV Trials Network

Completed

D4T or Abacavir Plus Vitamin Enhancement in HIV-Infected Patients (DAVE)

Acidosis, Lactic

Canada
Ottawa Hospital Research Institute
Canadian Institutes of Health Research (CIHR); Ontario HIV Treatment Network; CIHR Canadian HIV Trials Network

Completed

Combination Vaccination Before HIV Treatment Interruption

HIV Infections

Canada
Ottawa Hospital Research Institute
Ontario HIV Treatment Network; Public Health Agency of Canada (PHAC); CIHR Canadian...

Completed

Influenza Vaccine in HIV

HIV | Influenza

Canada
Ottawa Hospital Research Institute
Gilead Sciences; CIHR Canadian HIV Trials Network

Completed

HIV Drug Switch Followed by HCV Therapy in HIV-HCV Co-Infection (CTN289)

Hepatitis C, Chronic | Human Immunodeficiency Virus

Canada
HIV Prevention Trials Network
National Institute on Drug Abuse (NIDA); National Institute of Allergy and...

Completed

Integrated Treatment and Prevention for People Who Inject Drugs

HIV Positive

Indonesia, Ukraine, Vietnam
HIV Prevention Trials Network
National Institute on Drug Abuse (NIDA); National Institute of Allergy and...

Enrolling by invitation

INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit (INTEGRA)

HIV Infections | Opioid Use | Drug Use | Opioid-use Disorder

United States
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); National Institute...

Completed

Feasibility of HIV Prevention Cohort Studies Among Men Who Have Sex With Men in Sub-Saharan Africa

HIV

Kenya, Malawi, South Africa
University Health Network, Toronto
Merck Sharp & Dohme LLC; Canadian Institutes of Health Research (CIHR); Ontario... and other collaborators

Terminated

The HPV-SAVE Study Team: HPV Screening and Vaccine Evaluation in Men Who Have Sex With Men (HPV-SAVE)

Anal Cancer | Human Papillomavirus | Anal Dysplasia

Canada
University Health Network, Toronto
Canadian Institutes of Health Research (CIHR); CIHR Canadian HIV Trials Network

Completed

Structured Treatment Interruption for HIV Patients With Virologic Failure

HIV
HIV Prevention Trials Network
National Institute of Allergy and Infectious Diseases (NIAID); Gilead Sciences and other collaborators

Completed

Uptake and Adherence to Daily Oral PrEP as a Primary Prevention Strategy for Young African Women: A Vanguard Study

HIV

South Africa, Zimbabwe
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Terminated

Safety and Effectiveness of HIV-1 DNA Plasmid Vaccine and HIV-1 Recombinant Adenoviral Vector Vaccine in HIV-Uninfected, Circumcised Men and Male-to-Female (MTF) Transgender Persons Who Have Sex With Men

HIV Infections

United States

Clinical Trials Sponsored by HIV Prevention Trials Network

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Belgium

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations