Clinical Trials Sponsored by HLT Inc.

Total 35404 results

HLT Inc.

Withdrawn

HLT® Meridian® TAVR Valve System Early Feasibility Study for Aortic Regurgitation (RIVAL - AR EFS)

Aortic Regurgitation

United States
HLT Inc.

Completed

Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Feasibility Trial CANADA (RADIANT CANADA)

Aortic Valve Stenosis

Canada
HLT Inc.

Terminated

Transfemoral Replacement of Aortic Valve With HLT MeriDIAN Valve Early Feasibility Trial (RADIANT)

Aortic Valve Stenosis

United States
HLT Inc.

Completed

HLT transfemOral Replacement of aortIc Valve Via transcatherteriZatiON (HORIZON)

Aortic Valve Stenosis | Severe Aortic Stenosis

Germany
HLT Inc.

Terminated

HLT Meridian Valve CE Mark Trial (RADIANT CE)

Aortic Valve Stenosis

Canada
HLT Inc.

Withdrawn

HLT transfemOral Replacement of aortIc Valve Via transcatherteriZatiON CANADA (HORIZON CANADA)

Severe Aortic Stenosis

Canada
QLT Inc.

Completed

Oral QLT091001 in Retinitis Pigmentosa (RP) Subjects With an Autosomal Dominant Mutation in Retinal Pigment Epithelial 65 Protein (RPE65)

Retinitis Pigmentosa (RP)

Canada, Ireland
QLT Inc.

Completed

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

United States, Canada, Germany, Netherlands, United Kingdom
QLT Inc.

Terminated

A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Phase III Study of Tariquidar + Paclitaxel/Carboplatin as First-Line Therapy in Non-Small Cell Lung Cancer (NSCLC)

Stage IV Non-small Cell Lung Cancer | Stage IIIb Non-small Cell Lung Cancer
QLT Inc.

Completed

Dose Escalation Study With QLT0074 for Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia

United States, Canada
QLT Inc.

Terminated

A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Phase III Study of Tariquidar + Vinorelbine as First-Line Therapy in Non-Small Cell Lung Cancer (NSCLC)

Stage IV Non-small Cell Lung Cancer | Stage IIIb Non-small Cell Lung Cancer
QLT Inc.

Completed

Reduced Fluence Visudyne-Anti-VEGF-Dexamethasone In Combination for AMD Lesions (RADICAL) (RADICAL)

Macular Degeneration | Choroidal Neovascularization

United States, Canada
QLT Inc.

Terminated

Photodynamic Therapy (PDT) for Lower Urinary Tract Symptoms (PLUS)

Prostatic Hyperplasia

United States, Canada
QLT Inc.

Completed

Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT

Leber Congenital Amaurosis (LCA) | Retinitis Pigmentosa (RP)

United States, Canada, Denmark, Germany, Netherlands, Switzerland, United Kingdom
QLT Inc.

Completed

Evaluation of the Effects of Oral QLT091001 in Adults With Impaired Dark Adaptation

Impaired Dark Adaptation

United States
QLT Inc.

Completed

Repeated Treatments of QLT091001 in Subjects With Leber Congenital Amaurosis or Retinitis Pigmentosa (Extension of Study RET IRD 01)

LCA (Leber Congenital Amaurosis) | RP (Retinitis Pigmentosa)

Canada, United States, Germany, Netherlands, United Kingdom
QLT Inc.

Completed

Visudyne® in Occult (VIO)

Macular Degeneration
QLT Inc.

Completed

Phase II Study to Evaluate Tariquidar (XR9576), a Selective MDR-1 Inhibitor, in Chemotherapy Resistant Advanced Breast Cancer

Breast Neoplasms

United States
QLT Inc.

Terminated

A Phase II, Randomized, Cross-Over, Vehicle-Controlled, Double-Blind, Multicenter Study of the Safety, Pharmacodynamics, and Preliminary Efficacy of GHRP-1/AG in Subjects With ESRD on Hemodialysis

End Stage Renal Disease

United States
QLT Inc.

Completed

Safety and Tolerability of Retinoid QLT091001 in Healthy Volunteers

Healthy Human Volunteers

Canada
QLT Inc.
Novartis

Terminated

Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.

Nevoid Basal Cell Carcinoma Syndrome | Basal Cell Carcinoma | Gorlin Syndrome
Novartis
QLT Inc.

Completed

Photodynamic Therapy in Occult-Only Lesions (POOL)

Age-Related Macular Degeneration

Switzerland
Mati Therapeutics Inc.
QLT Inc.

Completed

A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)

Ocular Hypertension | Open-Angle Glaucoma

United States
Mati Therapeutics Inc.
QLT Inc.

Completed

A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG

Ocular Hypertension | Open-Angle Glaucoma

United States
Novartis Pharmaceuticals
QLT Inc.

Completed

A Safety and Efficacy Study Comparing the Combination Treatments of Verteporfin Therapy Plus One of Two Different Doses of Intravitreal Triamcinolone Acetonide and the Verteporfin Therapy Plus Intravitreal Pegaptanib (VERITAS)

Macular Degeneration | Choroidal Neovascularization

United States
Southeast University, China
QLT Inc.

Unknown

A Multicenter Observational Study of Invasive Candida Infections Among ICU Patients in China (china-scan)

Candidiasis

China
Barnes Retina Institute
QLT Inc.

Unknown

Study of Treatment Effects of Combination Therapy of Lucentis Plus Reduced Fluence PDT With Visudyne in Patients With Exudative AMD

Age-Related Macular Degeneration

United States
National Eye Institute (NEI)
QLT Inc.

Terminated

TAC-PF, Avastin® in Combination With Photodynamic Therapy to Treat Age Related Macular Degeneration (VERTACL)

Age-Related Macular Degeneration

United States
QLT Inc.

Completed

Photodynamic Therapy in Treating Patients With Stage III or Stage IV Melanoma

Melanoma (Skin)

United States
Bay Area Retina Associates
QLT Inc.

Completed

Triple Therapy - PDT Plus IVD and Intravitreal Ranibizumab Versus Lucentis Monotherapy to Treat Age-Related Macular Degeneration (PDEX)

Age Related Macular Degeneration

United States
NLT Spine

Unknown

Prospective Study To Assess The Safety and Efficacy of the PROW LIF Procedure

Degenerative Disc Disease

Israel
HTL-Strefa S.A.

Completed

Capillary Blood Volume and Pain Perception Obtained in a Process of Puncturing With Different Safety Lancets

Healthy

Poland
Manhattan Eye, Ear & Throat Hospital
QLT Inc.; Novartis

Completed

Study Of Combined VISUDYNE Therapy With Kenalog In CNV Secondary To Age-Related Macular Degeneration

Age-Related Macular Degeneration

United States, Canada
Vitreous -Retina- Macula Consultants of New York
QLT Inc.

Withdrawn

Second Line Therapy to Treat Age-related Macular Degeneration (AMD) for Patients Not Responding Well to Lucentis Therapy by Itself

Age Related Macular Degeneration
HTL-Strefa S.A.

Completed

Simulated Clinical Use Testing to Evaluate Sharps Injury Prevention Features of HTL-STREFA's Safety Lancets (Test C)

Accident Injury

United States
HTL-Strefa S.A.

Completed

The Characteristics of Different Personal Lancets on Blood Volume and Perceived Pain in Patients With Diabetes Mellitus

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1
HTL-Strefa S.A.

Completed

Characteristics of Different Types of Safety Lancets on Blood Volume and Perceived Pain in Male and Female Volunteers

Healthy

Poland
HTL-Strefa S.A.

Completed

Simulated Clinical Use Testing On Safety Lancets (Test B)

Needle Stick

United States
HTL-Strefa S.A.

Completed

Simulated Clinical Use Testing on Safety Lancets (Test A)

Needle Stick

United States
HTL-Strefa S.A.

Completed

Simulated Clinical Use Testing on the DropSafe Safety Pen Needle

Needle Stick

United States
HLB Pharmaceutical Co., Ltd.

Unknown

Phase 1 Single Dose Escalation Study of CTB-001

Healthy

Korea, Republic of
HLB Cell Co., Ltd.

Withdrawn

A Safety and Efficacy Study of Infusions of HepaStem in Urea Cycle Disorders Pediatric Patients

Urea Cycle Disorder

Korea, Republic of
HLB Cell Co., Ltd.

Completed

Study to Evaluate the Safety and Efficacy of HLBLS-200 in Patients Requiring Hemostatic Technique

Hemorrhage

Korea, Republic of
Vitreous -Retina- Macula Consultants of New York
QLT Inc.

Terminated

Bevacizumab in Combination With Verteporfin Reduced and Standard Fluence in the Treatment of Hemorrhaged Lesions in Neovascular AMD

Macular Degeneration

United States
HLB Pharmaceutical Co., Ltd.

Completed

C-Trelin Orally Disintegrated(OD) Tablet 5mg in Ataxia Due to Spinocerebellar Degeneration

Spinocerebellar Degeneration

Korea, Republic of
HLB Cell Co., Ltd.

Unknown

Study to Evaluate Safety and Efficacy of LifeLiver in Acute or Acute-on-Chronic Liver Failure Patients

Acute-On-Chronic Liver Failure | Acute Liver Failure

Korea, Republic of
Lawson Health Research Institute
QLT Inc.; Canadian Retinal Trials Group

Completed

Combination Therapy for Age-Related Macular Degeneration.

Age Related Macular Degeneration

Canada
Hat Yai Medical Education Center

Completed

The Correlations of FeNO, Blood Eosinophils and Lung Function in Well-controlled Asthma

Asthma

Thailand
Hat Yai Medical Education Center

Recruiting

Role of Parasympathetic Activity in Mild to Severe Asthma With Fixed Airway Obstruction (PARASMA Study) (PARASMA)

Asthma | Airway Obstruction | Airway Remodeling | Parasympathetic Nervous System Diseases

Thailand
Hat Yai Medical Education Center

Completed

As-needed Budesonide/Formoterol Turbuhaler in Stepping Down Period

Asthma

Thailand

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