Clinical Trials Sponsored by Hoffman Oncology

Total 6940 results

Hoffman Oncology
DSCS CRO

Active, not recruiting

Phase I Study of Combination of Gedatolisib With Palbociclib and Faslodex in Patients With ER+/HER2- Breast Cancer

Breast Cancer

United States
GERCOR - Multidisciplinary Oncology Cooperative...
Hoffmann-La Roche

Active, not recruiting

Multi-Line Therapy Trial in Unresectable Metastatic Colorectal Cancer (STRATEGIC-1)

Colorectal Cancer Metastatic

Ireland, France, Israel
Hoffmann-La Roche
Latin American Cooperative Oncology Group

Active, not recruiting

A Study to Describe the Diagnosis, Anti-Cancer Treatment and Clinical Outcome in Patients With Newly Diagnosed Breast Cancer in Latin America

Breast Cancer

Colombia, Guatemala, Peru, Argentina, Brazil, Chile, Cuba, Mexico, Dominican Republic, Uruguay
GERCOR - Multidisciplinary Oncology Cooperative...
Hoffmann-La Roche

Completed

Follow up to the AVANT Study up to 8 and 10 Years (Median Follow up) in Patients With Colon Carcinoma

Colon Cancer Treated With Bevacizumab After Colon Surgery

France
Ontario Clinical Oncology Group (OCOG)
Hoffmann-La Roche

Recruiting

Neoadjuvant Combination of Atezolizumab/Bevacizumab Versus Neoadjuvant Radiation Therapy (ADVANCE HCC)

Hepatocellular Carcinoma | Portal Vein Tumour Thrombosis

Canada
Ontario Clinical Oncology Group (OCOG)
Hoffmann-La Roche

Completed

A Feasibility Study of Co-administering Combination Antiretroviral Therapy (cART) and R-EPOCH Chemotherapy for the Management of ARL (CATCH)

HIV Infections | Lymphoma, AIDS Related

Canada
Accelerated Community Oncology Research Network
Hoffmann-La Roche; AstraZeneca

Completed

Phase II Trial of Capecitabine With Fulvestrant for Postmenopausal Women With Hormone Receptor Positive Metastatic Breast Cancer

Metastatic Breast Cancer

United States
Chang Gung Memorial Hospital
Hoffmann-La Roche; Asian Gynecologic Oncology Group; Taiwanese Gynecolgic Oncology...

Completed

Postoperative Adjuvant Chemotherapy With Bevacizumab and Maintenance Bevacizumab After Neoadjuvant Chemotherapy for Ovarian Cancer

Epithelial Ovarian Cancer

Taiwan
Mural Oncology, Inc
Immune Oncology Network

Completed

A Study of ALKS 4230 (Nemvaleukin Alfa) With Pembrolizumab in Head and Neck Cancer

Non-cutaneous Squamous Cell Carcinoma of Head and Neck

United States
Hirschfeld Oncology

Not yet recruiting

Clinical Trial Evaluating Low Dose G-FLIP Plus Mitomycin C for Stage IV Pancreatic Cancer (GFLIPM)

Pancreatic Cancer

United States
Ikena Oncology

Recruiting

Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects With Advanced Solid Tumors

Solid Tumor | Solid Tumors, Adult | Malignant Pleural Mesothelioma (MPM) | Epithelioid Hemangioendothelioma (EHE) | NF2 Deficient Mesothelioma | Other NF2 Deficient Solid Tumors and Solid Tumors With YAP1/TAZ Fusion Genes | NF2 Deficiency | YAP1 or TAZ Gene Fusions

United States, United Kingdom
CivaTech Oncology

Recruiting

Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®

Lung Cancer | Lung Cancer Stage I | Lung Cancer Stage II

United States
CivaTech Oncology

Recruiting

Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source

Pancreatic Cancer

United States
Cardiff Oncology

Active, not recruiting

Study of Onvansertib in Combination With FOLFIRI and Bevacizumab Versus FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer in Participants With a Kirsten Rat Sarcoma Virus Gene (KRAS) or Neuroblastoma-RAS (NRAS) Mutation

Metastatic Colorectal Cancer | Colorectal Cancer

United States
CivaTech Oncology

Completed

Initial Feasibility Study to Treat Resectable Pancreatic Cancer With a Planar LDR Source

Cancer | Pancreas Cancer

United States
CivaTech Oncology

Completed

Linear Source Registry for Prostate Cancer (CaRePC)

Prostate Cancer

United States
Elevation Oncology

Active, not recruiting

Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors

Sarcoma | Kidney Cancer | Breast Cancer | Head and Neck Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bladder Cancer | Metastatic Solid Tumor | Gallbladder Cancer | Uterine Cancer | Locally Advanced Solid Tumor

United States, Korea, Republic of, Australia, Canada
CureLab Oncology

Active, not recruiting

Efficacy of Plasmid Elenagen in Combination With Gemcitabine in Patients With Platinum-resistant Ovarian Cancer

Ovarian Cancer | Platinum-resistant Ovarian Cancer

Belarus
Strata Oncology

Enrolling by invitation

Sentinel™ Trial: A Prospective Study Evaluating the Performance and Clinical Benefit of Personalized ctDNA-based MRD Testing to Detect Recurrence and Monitor Treatment Response in Patients With Solid Tumors (Sentinel)

Cancer

United States
Que Oncology

Completed

Dose Escalation Study in Female Subjects With Breast Cancer Receiving Aromatase Inhibitor or Tamoxifen

Vasomotor Symptoms (VMS)
Bruckner Oncology

Completed

Ph 2 Trial of Vitamin C & G-FLIP (Low Doses Gemcitabine, 5FU, Leucovorin, Irinotecan, Oxaliplatin) for Pancreatic Cancer

Pancreatic Cancer

United States
Unidad Integral de Investigación en Oncología S.L.
Hoffmann-La Roche

Completed

1stline Study Capecitabine Administered on Continuous Way Plus Oxaliplatin&Bevacizumab Every 2weeks in Metastatic CCR.

Metastatic Colorectal Cancer

Spain
Radionetics Oncology

Recruiting

Phase 1 Study of 68Ga-R8760

Adrenocortical Carcinoma

United States
Elucida Oncology

Recruiting

A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FRα)

Ovarian Diseases | Ovarian Neoplasms | Ovarian Cancer | Ovarian Epithelial Cancer | Fallopian Tube Cancer | Endometrial Neoplasms | Endometrial Cancer | Endometrial Clear Cell Adenocarcinoma | Ovarian Carcinoma | Endometrial Adenocarcinoma | Peritoneal Cancer | Endometrioid Adenocarcinoma | Ovarian Adenocarcinoma | Ovarian Serous Adenocarcinoma and other conditions

United States
CivaTech Oncology

Not yet recruiting

CivaDerm(TM) Surface Therapy Pilot Study

Basal Cell Carcinoma | Squamous Cell Carcinoma of the Skin
Strata Oncology

Recruiting

Assessing the Clinical Benefit of Molecular Profiling in Patients With Solid Tumors

Lymphoma | Cancer | Adult Solid Tumor | Multiple Myeloma

United States
Cardiff Oncology

Completed

Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a Kras Mutation

Metastatic Colorectal Cancer | KRAS Gene Mutation

United States
Strata Oncology

Withdrawn

Strata EXPress™: A Study Using StrataEXP™ to Identify RNA-Expression Biomarkers in Advanced Cancer Patients (StrataEXPress)

Cancer

United States
Cardiff Oncology

No longer available

Expanded Access of Onvansertib With FOLFIRI and Bevacizumab for the Second-Line Treatment of Participants With KRAS-Mutated Metastatic Colorectal Cancer

Metastatic Colorectal Cancer | KRAS Gene Mutation
Cardiff Oncology

Active, not recruiting

Onvansertib in Combination With Nanoliposomal Irinotecan, Leucovorin, and Fluorouracil for Second-Line Treatment of Participants With Metastatic Pancreatic Ductal Adenocarcinoma

Pancreatic Ductal Adenocarcinoma

United States
Arch Oncology

Completed

Study of AO-176 as Monotherapy and in Combination With Bortezomib/Dexamethasone in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma

United States
Elevation Oncology

Terminated

Phase 2 Trial of Seribantumab Plus Fulvestrant in Postmenopausal Women With Metastatic Breast Cancer (SHERBOC)

Metastatic Breast Cancer

Germany, Spain, United States, Austria, Belgium, Canada
Alchemia Oncology

Unknown

Trial of FOLF(HA)Iri Versus FOLFIRI in mCRC (FOLF(HA)iri)

Metastatic Colorectal Cancer

Australia
Ikena Oncology

Recruiting

Study of IK-595 in RAS- or RAF-altered Advanced Tumors

Colorectal Cancer | Pancreatic Cancer | Thyroid Carcinoma | Solid Tumor, Adult | Malignant Melanoma | Non-Small Cell Lung Carcinoma | BRAF Gene Mutation | Gliomas, Malignant | Ras (Kras or Nras) Gene Mutation | CRAF Gene Mutation

United States
Elevation Oncology

Recruiting

Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2

Neoplasms | Neoplasms by Site | Gastrointestinal Neoplasms | Digestive System Neoplasm | Pancreas Neoplasm | Stomach Neoplasm

United States, Japan
Cardiff Oncology

Completed

Onvansertib in Combination With Abiraterone and Prednisone in Adult Patients With Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer

United States
Cardiff Oncology

Completed

Onvansertib in Combination With Either Low-dose Cytarabine or Decitabine in Adult Patients With Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
Surface Oncology

Completed

Study of SRF231 in Patients With Advanced Solid and Hematologic Cancers

Hematologic Cancers | Advanced Solid Cancers

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology; Southwest Oncology Group

Completed

Radiation Therapy With or Without Bicalutamide for Recurrent pT3N0 Prostate Cancer After Radical Prostatectomy

Prostate Cancer

United States, Canada
Maastricht Radiation Oncology

Recruiting

The Effect of 360° Virtual Reality Movies on Fear and Anxiety (ENGAGE)

Breast Cancer | Head and Neck Cancer | Anxiety | Lung Cancer | Prostate Cancer | Brain Tumor | Fear

Netherlands
Cullinan Oncology Inc.

Recruiting

CLN-617 Alone and in Combination With Pembrolizumab in Patients With Advanced Solid Tumors

Advanced Solid Tumor

United States
Taiho Oncology, Inc.

Recruiting

A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation. (REZILIENT2)

Advanced or Metastatic NSCLC Harboring Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertion (ex20ins) Mutations

United States, Japan, Spain, Italy, Korea, Republic of, Canada, France, Australia, Germany, United Kingdom, Hong Kong, Turkey
Taiho Oncology, Inc.

Recruiting

Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors

Pancreatic Cancer | Esophageal Adenocarcinoma | Esophageal Squamous Cell Cancer | Locally Advanced Unresectable or Metastatic Solid Tumors Including Esophageal Cancer | Siewert Type 1 GEJ Cancer

United States, Spain, Germany, France
Taiho Oncology, Inc.

Recruiting

A Study of TAS3351 in NSCLC Patients With EGFRmt (TAS3351)

Non-Small Cell Lung Cancer

United States, France, Italy, Korea, Republic of, Japan, Spain, Germany, Netherlands, United Kingdom
ALX Oncology Inc.

Recruiting

A Study of Evorpacept (ALX148) With Enfortumab Vedotin for Subjects With Urothelial Carcinoma (ASPEN-07)

Bladder Cancer | Urothelial Carcinoma

United States
Children's Oncology Group

Not yet recruiting

A Study With DAY101 as a Treatment Option for Progressive, Relapsed, or Refractory Langerhans Cell Histiocytosis

Recurrent Langerhans Cell Histiocytosis | Refractory Langerhans Cell Histiocytosis
RS Oncology LLC

Recruiting

Study of RSO-021 in Patients With Malignant Pleural Effusion Due to Advanced/Metastatic Solid Tumors Including Mesothelioma

Mesothelioma | Malignant Pleural Mesothelioma | Pleural Effusion, Malignant | Mesotheliomas Pleural | Malignant Pleural Effusion | Mesothelioma; Lung

United Kingdom
Maastricht Radiation Oncology

Recruiting

Lung Cancer Organoids and Patient Derived Tumor Xenografts (Lung organoids)

Lung Cancer

Netherlands
Kura Oncology, Inc.

Recruiting

Combination Trial of Tipifarnib and Alpelisib in Adult Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC)

HNSCC

United States
Taiho Oncology, Inc.

Recruiting

A Study of TAS2940 in Participants With Locally Advanced or Metastatic Solid Tumor Cancer

Breast Cancer | Glioblastoma | Solid Tumor | Non-small Cell Lung Cancer

United States, France

Clinical Trials Sponsored by Hoffman Oncology

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