Clinical Trials Sponsored by ISAE-SUPAERO

Total 86 results

University Hospital, Toulouse
ISAE-SUPAERO

Terminated

Modulation and Assessment of Mental Flexibility in Dysexecutive Brain Patients (MODEX)

Dysexecutive Syndrome

France
ISAR Klinikum

Active, not recruiting

Influence of RIC on the Orthostatic Competence of the Microcirculation

Orthostatic Intolerance | Remote Ischemic Preconditioning | Hemodynamics | Microcirculation

Germany
SAE Orthopedics

Not yet recruiting

Novel Stretching Device Versus Night Splints

Plantar Fasciitis

United States
Ambrosia - SupHerb Ltd.

Unknown

Comparative Efficacy and Tolerability of No7 in Osteoarthritis of the Knee

Osteoarthritis, Knee
Klinik Bogenhausen
ISAR Klinikum

Completed

Efficacy of Postoperative Epidural Anesthesia Following Abdominoplasty (EDA)

Anesthesia | Abdominoplasty

Germany
Spero Therapeutics

Completed

A Study to Evaluate the Effect of Co-administration on the Pharmacokinetics of SPR720, Azithromycin, and Ethambutol in Healthy Participants

Healthy Volunteers

United States
Spero Therapeutics

Completed

Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
ISA Associates, Inc.

Recruiting

Mobile Stress Management Program for African American Women

Psychological Stress

United States
ISA Associates, Inc.

Completed

Improving HIV Outcomes Among African American Transgender Women

HIV

United States
ISA Associates, Inc.

Recruiting

A Smartphone-Based Intervention to Improve Colorectal Cancer Screening in African American Men

Colorectal Cancer

United States
Max Health, Subsero Health

Recruiting

An Outpatient Clinical Trial Using Ivermectin and Doxycycline in COVID-19 Positive Patients at High Risk to Prevent COVID-19 Related Hospitalization

Covid19

United States
Spero Therapeutics

Recruiting

A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease

Nontuberculous Mycobacterial Pulmonary Disease (NTM-PD)

United States
Spero Therapeutics

Completed

A Study to Assess the Intrapulmonary Pharmacokinetics (PK) of SPR719 by Comparing the Plasma, Epithelial Lining Fluid, and Alveolar Macrophage Concentrations Following the Oral Administration of Multiple Doses of SPR720 in Healthy Volunteers.

Healthy Volunteer

United States
Spero Therapeutics

Completed

A Study to Compare Two Bioanalytical Assays for Tebipenem

Healthy Volunteers

United States
Spero Therapeutics

Completed

Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (ADAPT-PO)

Acute Pyelonephritis | Complicated Urinary Tract Infection

Bulgaria, Georgia, United States, Czechia, Estonia, Hungary, Latvia, Moldova, Republic of, Poland, Romania, Russian Federation, Serbia, Slovakia, South Africa, Ukraine
Spero Therapeutics

Terminated

Safety, Tolerability, Pharmacokinetics and Efficacy of SPR720 for the Treatment of Patients With Mycobacterium Avium Complex (MAC) Pulmonary Disease

Mycobacterium Avium Complex | Non-tuberculous Mycobacterium Pulmonary Disease

United States
Spero Therapeutics

Completed

Phase 1 Study of PK and Safety of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Subjects With Various Degrees Of Renal Function

Renal Impairment

United States
Spero Therapeutics

Completed

Bioequivalence Study Comparing Two Tablet Formulations of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects

Healthy Volunteers

United States
ISAVE- Instituto Superior de Saúde

Recruiting

Validation of a Mobile App as an Adjuvant Treatment (VMA)

Validation

Portugal
ISA Pharmaceuticals
Regeneron Pharmaceuticals

Active, not recruiting

A Phase II Study of Cemiplimab and ISA101b in Patients With Recurrent/Metastatic HPV16 Positive OPC

Squamous Cell Carcinoma of the Oropharynx

United States, Israel, Belgium, Germany, Spain, United Kingdom, Italy, France, Czechia
Super Inspired LLC

Recruiting

Nirvana Super Pro Supplementation in Orthopedic Surgery Patients

Arthropathy of Knee | Arthropathy of Hip

United States
Spero Therapeutics
GlaxoSmithKline

Recruiting

A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (PIVOT-PO)

Urinary Tract Infection | Acute Pyelonephritis

Moldova, Republic of, Georgia, United States, Serbia, Bulgaria, Romania, South Africa
Spero Therapeutics
Covance

Completed

Study of the Absorption, Metabolism, and Excretion of [14C]-Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) Following a Single Oral Dose in Healthy Male Subjects

Healthy Volunteers

United States
ISA Pharmaceuticals
Regeneron Pharmaceuticals

Active, not recruiting

A Randomized Phase 2 Study of Cemiplimab ± ISA101b in HPV16-Positive OPC

Squamous Cell Carcinoma of the Oropharynx | HPV16 Positive

Netherlands, United States, United Kingdom, France, Belgium, Czechia, Spain, Italy, Germany, Brazil, Hungary, Mexico, Poland
Spero Therapeutics
Clinartis

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR859 by Comparing the Plasma, Epithelial Lining Fluid (ELF), and Alveolar Macrophages (AM) Concentrations Following the Oral Administration of Five Doses of SPR994 in Healthy, Nonsmoking Volunteers

Healthy Volunteers

United States
McGill University
Super Sublime | Super Splendide; Résidences Enharmonie

Completed

The Effects of a Nature-Based Mindfulness-Compassion Intervention for Older Adults Delivered Using Virtual Reality

Healthy Aging | Mental Health Wellness 1

Canada
Spero Therapeutics
Celerion

Completed

A Single-Dose, Randomized, Placebo- and Active-Control, Four-Way, Cross-Over Study for the Evaluation of the Effect of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) on the QT/QTc Intervals in Adult Healthy Subjects

TQT Study

United States
Hartford Hospital
Spero Therapeutics

Completed

Tebipenem (SPR994) Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis

Diabetes | ABSSSI | Healthy Volunteers | Wound Infection

United States
Your Super, INC.
Citruslabs

Completed

Study to Evaluate the Efficacy of YOUR SUPER Detox Bundle to Improve Perceived Well Being and Promote Adaptation of Healthy Dietary Choices

Healthy Diet | Eating Habit

United States
Spero Therapeutics
Simbec Research

Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of SPR720 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Max Super Speciality Hospital

Completed

Nasogastric Versus Orogastric Route of Feeding in Preterm (<32 Weeks) Neonates

Apnea Prematurity
Rabin Medical Center
Ambrosia - SupHerb Ltd.

Completed

The Effect of Probiotics on Lactose Intolerance (PLI)

Lactose Intolerance
Meir Medical Center
Ambrosia - SupHerb Ltd.

Completed

Probiotics for the Prevention of Major Complications of Cirrhosis

Liver Cirrhosis

Israel
ISA Pharmaceuticals
Dutch Cancer Society

Completed

Study of the Therapeutic Vaccine (ISA101/ISA101b) to Treat Advanced or Recurrent Cervical Cancer (CervISA)

Cervical Cancer

Germany, Netherlands, Belgium
Regeneron Pharmaceuticals
ISA Pharmaceuticals B.V.

Active, not recruiting

Cemiplimab and ISA101b Vaccine in Adult Participants With Recurrent/Metastatic Human Papillomavirus (HPV)16 Cervical Cancer Who Have Experienced Disease Progression After First Line Chemotherapy

Cervical Cancer

Spain, Korea, Republic of, Netherlands, Brazil, Belgium, United States, Italy, Russian Federation
Mosaad Khalifah

Unknown

A Novel Technique to Anaesthetize the Lower Jaw (NTALJ)

Inferior Alveolar Nerve Block

Egypt
Hartford Hospital
Spero Therapeutics

Completed

Bioavailability of Tebipenem (SPR994) Crushed Tablet

Relative Bioavailability

United States
Your Super, INC.
Citruslabs

Completed

Study to Evaluate Your Super's Moon Balance and Its Impact on Premenstrual Syndrome

Menstrual Pain | PMS | Menstrual Discomfort

United States
Erasmus Medical Center
ISA Pharmaceuticals B.V.

Recruiting

Evaluation of the Novel Therapeutic Hepatitis B Virus Synthetic Long Peptide Vaccination ISA104 (HEB-PEP)

Chronic Hepatitis b

Netherlands
University of Southampton
Isle of Wight NHS Trust

Completed

MAPS & ITEC Cohorts: 6-8 Years Follow-up

Asthma | Immunotherapy | Allergy and Immunology

United Kingdom
Spero Therapeutics
Iqvia Pty Ltd

Completed

Effect of Tebipenem on Normal Human Intestinal Microbiota

Healthy Volunteers

Sweden
ISAR-M GmbH
CRI-The Clinical Research Institute GmbH

Not yet recruiting

Thyroid HEmorrhage DetectOr Study (HEDOS)

Thyroid
Universidad del Desarrollo
Klinikum rechts der Isar Technische Universität München

Recruiting

Evaluation of the EEG Connectivity Using Predominant Dexmedetomidine as Anesthetic in Fragile Brains (BaseDexmed)

Aging Problems

Chile
M.D. Anderson Cancer Center
Pfizer; ISA Pharmaceuticals B.V.

Completed

Utomilumab and ISA101b Vaccination in Patients With HPV-16-Positive Incurable Oropharyngeal Cancer

Oropharyngeal Cancer | Malignant Neoplasms of Ill-defined Secondary and Unspecified Sites | Malignant Neoplasms of Lip Oral Cavity and Pharynx

United States
Spero Therapeutics
United States Department of Defense

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR206 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Spero Therapeutics
Simbec Research; QPS Holdings LLC

Completed

Phase 1 Study to Evaluate DDI, PK, Safety, Tolerability of SPR741

Healthy Volunteers

United Kingdom
Isle of Wight NHS Trust
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Long-Term Examination of Asthma From Childhood Through Adolescence

Asthma | Rhinitis | Dermatitis, Atopic | Urticaria

United Kingdom
Spero Therapeutics
United States Department of Defense

Completed

Phase 1 Study of PK and Safety of SPR206 in Subjects With Various Degrees Of Renal Function

Renal Impairment

New Zealand
AHEPA University Hospital
LABNET IAE - Private Reference Diagnostic Laboratory

Unknown

Development of a Risk Prediction Algorithm Through the Investigation of Genetic Risk Factors and the Complexity of Coronary Artery Disease to Estimate Future Risk of Cardiovascular Events: Angiographic (SYNTAX Score), Clinical and Pharmacogenetic Analysis. (GESS)

Coronary Artery Disease

Greece
M.D. Anderson Cancer Center
Bristol-Myers Squibb; ISA Pharmaceuticals B.V.

Completed

Nivolumab and HPV-16 Vaccination in Patients With HPV-16 Positive Incurable Solid Tumors

Solid Tumors

United States

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