Clinical Trials Sponsored by Ikfe-CRO GmbH

Total 424 results

ikfe-CRO GmbH
MLM Medical Labs GmbH; Ikfe GmbH

Completed

Effects of Linagliptin on Endothelial- , Renal-, and Retinal Function in Patients With Hypertension and Albuminuria

Albuminuria | Arterial Hypertension

Germany
ikfe-CRO GmbH
IKFE Institute for Clinical Research and Development

Completed

Beta-Cell Function of Insulin Glargine Compared to Neutral Protamine Hagedorn (NPH) Insuline and to Insulin Detemir in Combination With Metformin

Type 2 Diabetic Patients | Insufficient Metabolic Control | OAD Treatment

Germany
Abbott Diabetes Care
ikfe-CRO GmbH

Completed

Comparison Study of Blood Glucose Monitoring Systems in People With Diabetes

Diabetes Mellitus

Germany, Netherlands
ikfe-CRO GmbH
IKFE Institute for Clinical Research and Development

Unknown

Human Insulin Analogs: Evaluation of Inflammatory mRNA Expression of Macrophages and Endothelial Function of Short-acting Insulin - HERMES Pilot Study (HERMES)

Type 2 Diabetes Mellitus

Germany
ikfe-CRO GmbH
IKFE Institute for Clinical Research and Development

Unknown

Establishing Cardiovascular Biomarkers to Define Preferred Lantus® Use

Insulin-requiring Type 2 Diabetes Mellitus

Germany
Marcus Borchert
Boehringer Ingelheim; ikfe-CRO GmbH

Unknown

Effect of Linagliptin in Comparison With Glimepiride as Add on to Metformin on Postprandial Beta Cell Function, Postprandial Metabolism and Oxidative Stress in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus Type 2

Germany
ikfe-CRO GmbH
AstraZeneca; IKFE Institute for Clinical Research and Development

Unknown

Investigation of a Switch From Insulin Therapy to a Metformin & Saxagliptin Combination in Patients With Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Germany
ikfe-CRO GmbH
Sanofi; IKFE Institute for Clinical Research and Development

Completed

Beta Cell Relieving and Cardiovascular Protective Effects of LANTUS Treatment in Type 2 Diabetes Patients

Diabetes Mellitus, Type 2

Germany
ikfe-CRO GmbH
Novartis Pharmaceuticals; IKFE Institute for Clinical Research and Development

Unknown

Effect of Adding Vildagliptin on Beta Cell Function and Cardiovascular Risk Markers in Patients With Moderate Metabolic Control During Metformin Monotherapy

Diabetes Mellitus Type II

Germany
ikfe-CRO GmbH
Novo Nordisk A/S; IKFE Institute for Clinical Research and Development

Completed

Impact of Liraglutide on Endothelial Function and Microvascular Blood Flow in Type 2 Diabetes Mellitus

Diabetes Mellitus, Type 2

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Thoraxklinik-Heidelberg gGmbH

Active, not recruiting

Thoracic RadiothErapy With Atezolizumab in Small Cell lUng canceR Extensive Disease (TREASURE)

Thoracic Radiotherapy | Small Cell Lung Cancer Extensive Stage

Germany, Austria
Institut für Klinische Krebsforschung IKF GmbH...
AstraZeneca; Thoraxklinik-Heidelberg gGmbH

Recruiting

Thoracic Radiotherapy Plus Durvalumab in Elderly and/or Frail NSCLC Stage III Patients Unfit for Chemotherapy (TRADE-hypo)

NSCLC, Stage III

Germany
Implandata Ophthalmic Products GmbH
CRO Dr. med. Kottmann GmbH & Co. KG

Active, not recruiting

Long-term Safety and Performance of the ARGOS-SC Suprachoroidal Pressure Sensor System in Patients With Glaucoma Underwent Non-penetrating Glaucoma Surgery

Glaucoma | Open Angle Glaucoma

Germany, Switzerland
Implandata Ophthalmic Products GmbH
CRO Dr. med. Kottmann GmbH & Co. KG

Completed

Performance and Safety of the ARGOS-SC01 Suprachoroidal Pressure Sensor in Patients With Glaucoma Undergoing Non-penetrating Glaucoma Surgery (ARGOS-SC01)

Glaucoma | Open Angle Glaucoma

Germany, Switzerland
ViMREX GmbH
Frankfurter Institut für Klinische Krebsforschung IKF GmbH am Krankenhaus...

Active, not recruiting

Clinical Trial With Local Decitabine Treatment of HPV-Induced VIN Grade 2/3 (DelVIN) (DelVIN)

Vulvar Intraepithelial Neoplasia Grade 2 | Vulvar Intraepithelial Neoplasia Grade 3

Germany
ITM Solucin GmbH
ABX CRO; PSI CRO

Active, not recruiting

Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients (COMPETE)

Neuroendocrine Tumors

Germany, France, United States, United Kingdom, Australia, Italy, Belgium, Switzerland, Czechia, Spain, Austria, Netherlands, Poland, South Africa
WiSP Wissenschaftlicher Service Pharma GmbH
Mundipharma Research GmbH & Co KG; Klinikum Leverkusen gGmbH; ribosepharm GmbH

Completed

Bendamustine Versus Fludarabine in Chronic Lymphocytic Leukemia (CLL)

Chronic Lymphocytic Leukemia

Germany
AIO-Studien-gGmbH
Bayer; Institut für Klinisch-Onkologische Forschung (IKF) am Krankenhaus Nordwest...

Completed

Regorafenib in Combination With TAS-102 in Subjects With Metastatic Colorectal Cancer Who Have Progressed After Standard Therapy (REMETY)

Pretreated Metastatic Colorectal Cancer

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Roche Pharma AG; Thoraxklinik-Heidelberg gGmbH

Recruiting

NeoTRACK - Dissection of IO Efficacy in NSCLC by Longitudinal tracKing

Non-small Cell Lung Cancer

Germany
Organon and Co
CRS Mannheim GmbH

Completed

A Trial to Assess the Pharmacokinetic Profile (e.g., Uptake, Distribution and Excretion of a Substance in the Body) of Nomegestrol Acetate (NOMAC), Estradiol (E2) and Estrone (E1) After Multiple and Single Dose Administration of the Combined Oral Contraception NOMAC-E2 (COMPLETED)(P05822)

Healthy
Peter Brehm GmbH
P.R.I.S.M.A.-CRO

Completed

Combined Prospective and Retrospective Post-Market Follow Up of the 'BPK-S Integration' UC as Primary Implant in the Variant CoCr

Osteoarthritis, Knee | Joint Instability

Belgium
Peter Brehm GmbH
P.R.I.S.M.A.-CRO

Terminated

Post-market Follow up Study of the 'BPK-S Integration' UC as Primary Implant in the Variants CoCr or Ceramic

Arthritis | Rheumatic Diseases | Osteoarthritis | Osteoarthritis, Knee | Joint Instability | Musculoskeletal Disease | Joint Disease

Austria
Cytonet GmbH & Co. KG
CRS Clinical Research Services Mannheim GmbH

Completed

Study in Healthy Subjects, Patients With Urea Cycle Disorders (UCD) and Carriers of UCD Mutations to Evaluate Urea Cycle Function

Urea Cycle Disorders

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Trium Analysis Online GmbH

Completed

FLOT vs. FLOT/Herceptin/Pertuzumab for Perioperative Therapy of HER-2 Expressing Gastric or GEJ Cancer (PETRARCA)

Stomach Cancer | Gastroesophageal Junction Cancer

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

The PLATON Network (PLATON)

Stomach Cancer | Pancreatic Cancer | Cholangiocarcinoma | Gallbladder Cancer | Hepatocellular Cancer | Oesophageal Cancer

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

New Prospective Expanded German Registry of Incidental Gallbladder Carcinoma (PERSUASION)- a Permanent Platform Including All Kind of Biliary Tract Cancers (BTC)

Biliary Tract Cancer | Neoadjuvant, Adjuvant and 1st Line

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

The ABC-HCC Trial: Atezolizumab Plus Bevacizumab vs. Transarterial Chemoembolization (TACE) in Intermediate-stage HepatoCellular Carcinoma

Hepatocellular Carcinoma

Austria, Germany, Spain, Japan, Italy, France
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Chemotherapy and Pembrolizumab, Followed by Pembrolizumab and Olaparib as Firstline Therapy in Her-2 Negative Gastric/GEJ Adenocarcinoma

Esophagogastric Adenocarcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Completed

Ramucirumab Plus TAS-102 in Patients With Advanced or Metastatic Gastric Adenocarcinoma or the Gastroesophageal Junction (RE-ExPEL)

Gastric Adenocarcinoma | Metastatic Adenocarcinoma of the Gastroesophageal Junction

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Completed

Study With Cabazitaxel in Previously Treated Patients With Advanced or Metastatic Gastric Cancer

Gastric Cancer

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Feasibility and Safety of IMP321 (Eftilagimod Alpha) for Advanced Stage Solid Tumors

Solid Tumors | Peritoneal Carcinomatosis

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Advancing Brigatinib Properties in ALK+ NSCLC Patients by Deep Phenotyping

NSCLC

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Modified FOLFOX Plus/Minus Nivolumab and Ipilimumab vs. FLOT Plus Nivolumab in Patients With Previously Untreated Advanced or Metastatic Gastric Cancer

GastroEsophageal Cancer | Adenocarcinoma of the Stomach

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Terminated

Trial Comparing Parenteral Nutrition (PN) Using Eurotubes® vs. 2/3-chamber Bags in Subjects With Solid Tumors Requiring PN (PEKANNUSS) (PEKANNUSS)

Solid Tumor

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Terminated

CaboCHECK - Cabozantinib in Adult Patients With Advanced Renal Cell Carcinoma Following Prior Systemic Check Point Inhibition Therapy: a Retrospective, Non-interventional Study

Advanced Renal Cell Carcinoma (All Subtypes) | Metastatic Renal Cell Carcinoma (All Subtypes)

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Completed

FLOT vs. FLOT/Ramucirumab for Perioperative Therapy of Gastric or GEJ Cancer (RAMSES) (RAMSES/FLOT7)

Stomach Cancer | Gastroesophageal Junction Cancer

Germany, Italy
Institut für Klinische Krebsforschung IKF GmbH...
Bristol-Myers Squibb; Eisai GmbH

Completed

Immunotherapy With Nivolumab in Combination With Lenvatinib for Advanced Stage Hepatocellular Carcinoma

Advanced Hepatocellular Carcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Discontinuation of CDK4/6 Inhibitors in Patients With Metastatic HR Positive, HER2 Negative Breast Cancer

Breast Cancer

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Organ Preservation With Durvalumab-based Immunotherapy in Combination With Chemoradiation as Definitive Therapy for Early Stage Esophageal Adenocarcinoma With Indication for Radical Surgery

Esophagus Adenocarcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Treatment of Atezolizumab and Derazantinib in Patients With Advanced iCCA With FGFR2 Fusions/Rearrangements

Intrahepatic Cholangiocarcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

GISAR German Interdisciplinary Sarcoma Registry (GISAR)

Sarcoma | Carcinosarcoma | Sarcoma,Soft Tissue | Sarcoma of Bone

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Recruiting

Ramucirumab Plus FOLFIRI Versus Ramucirumab Plus Paclitaxel in Patients With Advanced or Metastatic Gastric Cancer, Who Failed One Prior Line of Palliative Chemotherapy (RAMIRIS)

Advanced Gastric or EGJ Cancer

Germany, Austria, Italy
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Comprehensive Genomic Profiling Combined With Real Life Data of "The German-Registry of Incidental Gallbladder Carcinoma"

Gallbladder Carcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer

Intrahepatic Cholangiocarcinoma | Hilar Cholangiocarcinoma | Distal Cholangiocarcinoma | Gall Bladder Carcinoma | Biliary Tract Cancer (CCA)

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Active, not recruiting

IMMULAB - Immunotherapy With Pembrolizumab in Combination With Local Ablation in Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma (HCC)

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Completed

Intravenous Ferric Carboxymaltose vs. Oral Iron Substitution in Patients With Metastatic Colorectal Cancer (CRC) and Iron Deficiency Anemia: a Randomized Multicenter Treatment Optimization Study.

Metastatic Colorectal Cancer

Germany
Institut für Klinische Krebsforschung IKF GmbH...

Terminated

OlaReDo - Olaratumab and Rechallenge With Doxorubicin in Soft Tissue Sarcoma Patients

Advanced Soft Tissue Sarcoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Trium Analysis Online GmbH; mca Berlin

Completed

Observational Study on Quality of Life of Patients Receiving Nab-paclitaxel/Gemcitabine First Line Therapy, Including a Translational Program (QoliXane)

Metastatic Pancreatic Cancer

Germany
Dr. Loges & Co. GmbH
BioTeSys GmbH

Completed

Effect of L-Arginine and Pycnogenol on Light to Moderate Hypertension and Endothelial Function

Endothelial Dysfunction | Hyperhomocysteinemia | Hypertension Grade I, Subgroup "Borderline" (WHO)

Germany
I-Med-Pro GmbH

Completed

CardioFocus vs. Contact Force Guided Pulmonary Vein Isolation in Paroxysmal Atrial Fibrillation (CF²)

Paroxysmal Atrial Fibrillation

Germany, United Kingdom, Czechia, Belgium

Clinical Trials Sponsored by Ikfe-CRO GmbH

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