Clinical Trials Sponsored by ImPACT Applications, Inc.

Total 45 results

ImPACT Applications, Inc.

Recruiting

ImPACT Normative Extension

Brain Concussion

United States
ImPACT Applications, Inc.

Terminated

Development of a Neurocognitive Screening Test

Brain Concussion | Mild Cognitive Impairment

United States
ImPACT Applications, Inc.

Active, not recruiting

ImPACT Version 4-Touchscreen: Normative and Reliability Study

Concussion

United States
ImPACT Applications, Inc.

Completed

ImPACT Online Clinical Study

Brain Concussion

United States
Impact Therapeutics, Inc.

Completed

BA Study of IMP4297 (20mg vs 10mg) in Healthy Male Subjects

Solid Tumor

Australia
Impact Therapeutics, Inc.

Unknown

Study of IMP4297 in Patients With BRCA1/2 Mutation Ovarian Cancer (SABRINA)

Ovarian Cancer

China
Impact Therapeutics, Inc.

Not yet recruiting

An BE Study to Compare 10mg & 20mg of IMP4297 Capsules in Healthy Chinese Subjects Under Fasting Condition

Solid Tumor
Impact Therapeutics, Inc.

Recruiting

Study to Evaluate IMP9064 as a Monotherapy or in Combination in Patients With Advanced Solid Tumors

Solid Tumor | Advanced Solid Tumor

China, Taiwan, United States, Australia
Impact Therapeutics, Inc.

Not yet recruiting

A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects

Solid Tumor
Impact Therapeutics, Inc.

Not yet recruiting

Senaparib in mCRPC Patients With Homologous Recombination Repair Gene Alterations After Docetaxel Treatment

mCRPC

Australia, United States, China
Impact Therapeutics, Inc.

Recruiting

IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer

Small Cell Lung Cancer | Advanced Solid Tumours

Taiwan, Korea, Republic of, China, Australia, United States
Impact Therapeutics, Inc.

Completed

The Safety and Pharmacokinetics of IMP4297 in Patients With Advanced Solid Tumors

Breast Cancer | Ovarian Cancer | Prostate Cancer | Primary Peritoneal Cancer | Advanced Solid Tumours

Australia
Impact Therapeutics, Inc.

Not yet recruiting

An BE Study to Compare 10mg & 20mg of IMP4297 Capsules in Healthy Chinese Subjects Under Fed Condition

Solid Tumor
Impact Therapeutics, Inc.

Completed

IMP4297 DDI (Drug-Drug Interaction)Trial in Healthy Male Volunteers

Solid Tumor

China
Impact Therapeutics, Inc.

Completed

A Study of IMP4297 in Patients With Advanced Solid Tumors

Breast Cancer | Ovarian Cancer | Prostate Cancer | Advanced Solid Tumours

China
Impact Therapeutics, Inc.

Completed

IMP4297 Food Effect Trial in Healthy Volunteers

Solid Tumor

China
Impact Therapeutics, Inc.

Unknown

A Study of IMP4297 as Maintenance Treatment Following First-line Chemotherapy in Patients With Advanced Ovarian Cancer (FLAMES)

Ovarian Cancer

China
Impact Therapeutics, Inc.
Covance

Recruiting

The Safety and Pharmacokinetics Preliminary Efficacy of IMP7068 in Patients With Advanced Solid Tumors (WEE1)

Advanced Solid Tumors

United States, Taiwan, China
Eikon Therapeutics
Impact Therapeutics, Inc.

Recruiting

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

Advanced Solid Tumor

Australia, United States
PACT Pharma, Inc.

Suspended

A Study of Gene Edited Autologous Neoantigen Targeted TCR T Cells With or Without Anti-PD-1 in Patients With Solid Tumors

Solid Tumor

United States
IMAC Holdings, Inc.

Unknown

Evaluate Umbilical Cord-derived Allogeneic Mesenchymal Stem Cells for the Treatment of Bradykinesia

Bradykinesia

United States
APR Applied Pharma Research s.a.
Cavendish Impact Foundation; Clinigen, Inc.; Nephron Pharmaceuticals, Inc.

No longer available

ZYESAMI (Aviptadil) Intermediate Population Expanded Access Protocol (SAMICARE) (SAMICARE)

Critical COVID-19 With Respiratory Failure

United States
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Active, not recruiting

An Efficacy and Safety Study of Fedratinib Compared to Best Available Therapy in Subjects With DIPSS-intermediate or High-risk Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, or Post-essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib (FREEDOM2)

Primary Myelofibrosis | Myelofibrosis | Post-Polycythemia Vera

Australia, Austria, Belgium, China, Czechia, France, Germany, Hungary, Italy, Korea, Republic of, Netherlands, Poland, Russian Federation, Spain, Ireland, United Kingdom
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

A Trial of Fedratinib in Subjects With DIPSS, Intermediate or High-Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib (FREEDOM)

Primary Myelofibrosis | Myelofibrosis | Post-Polycythemia Vera Myelofibrosis | Post-essential Thrombocythemia Myelofibrosis

United States, Canada
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

A Pharmacokinetics and Tolerability Study of Fedratinib in Subjects With Moderate and Severe Hepatic Impairment

Healthy Volunteers | Hepatic Impairment

United States
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

A Study to Evaluate the Effect of a Dual CYP2C19 and CYP3A4 Inhibitor, Fluconazole, on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects

Healthy Volunteers

United States
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Available

Individual Patient Compassionate Use of Fedratinib

Myelofibrosis

United States
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

Effect of Rifampin and Efavirenz on the Pharmacokinetics of Fedratinib in Healthy Adult Subjects

Healthy Volunteers

United States
Celgene
Impact Biomedicines, Inc., a wholly owned subsidiary of Celgene Corporation

Completed

Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and Metformin

Healthy Volunteers

United States
Eric Levian
Duke University

Completed

Vivo Prediabetes Study: Online, Live, and Interactive Strength Training for Older Adults With Prediabetes

Muscle Weakness | PreDiabetes | Older Adults | Muscle Loss

United States
Columbia University
Research Foundation for Mental Hygiene, Inc.; Impact Research & Development...

Not yet recruiting

IPrEP Men's Study: Expanding the Reach of Prevention for Men in Kisumu, Kenya

HIV
RTI International
National Institute of Mental Health (NIMH); SisterLove, Inc.; Positive Impact...

Not yet recruiting

The IMPROV Project: Improving Mental Health and Substance Use Treatment Provision (IMPROV) Among People Living With HIV (Human Immunodeficiency Virus) in Atlanta (IMPROV)

Substance Use Disorder | Mental Health Disorder | Implementation Science | Stigmatization

United States
Harvard School of Public Health (HSPH)
John Snow, Inc.; International Initiative for Impact Evaluation

Completed

Zambian Peer-Educators for HIV Self-Testing Study (ZEST)

HIV Infection

Zambia
Joint Implant Surgeons, Inc.
Medtronic; Mount Carmel Health System

Completed

Efficacy of Aquamantys for Reducing Transfusions With Anterior Supine Intermuscular Approach Total Hip Arthroplasty (Aquamantys)

Arthritis, Rheumatoid | Osteonecrosis | Hip Dislocation, Congenital | Osteoarthritis, Hip | Joint Deformities, Acquired

United States
SOLTI Breast Cancer Research Group
Merck Sharp & Dohme LLC; Pfizer; AstraZeneca; Astellas Pharma Inc; Advanced Accelerator... and other collaborators

Recruiting

Feasibility and Impact of Liquid Biopsy Genomic Profiling on Treatment Patients With Metastatic Prostate Cancer in Spain (SOLTI-2102) (HOPE-PROSTATE)

Metastatic Prostate Cancer

Spain
Harvard University
Weiss Family Program Fund for Research in Development Economics; Harvard Lab...

Completed

Study on Mhealth and Reproductive Health in Teens (SMART)

Reproductive Health

Ghana
Rush University Medical Center
Thomas Jefferson University; Central DuPage Hospital; Joint Implant Surgeons,...

Completed

Articulating Versus Static Antibiotic Loaded Spacers for the Treatment of Prosthetic Knee Infection

Osteoarthritis | Prosthetic Joint Infection | Complications; Arthroplasty | Complications; Arthroplasty, Infection or Inflammation | Knee Infection

United States
Rutgers, The State University of New Jersey
National Institute of Mental Health (NIMH); Positive Impact Health Centers; THRIVE...

Completed

Testing THRIVE 365 for Black Sexual Minority Men (On The Daily) (OTD)

Medication Adherence | Depressive Symptoms | Anxiety Symptoms | Emotion Regulation

United States
Rutgers, The State University of New Jersey
Columbia University; Emory University; George Washington University; Arizona State... and other collaborators

Not yet recruiting

Examining the Health Effects of iTHRIVE 365 Among Black Same Gender Loving Men

Medication Adherence | Depressive Symptoms | Anxiety Symptoms | Social Stigma | Sexual and Gender Minorities
University of British Columbia
iACT - Innovations in Acute Care and Technology

Completed

Paper vs. Internet (P vs I)

Adolescent | Idiopathic Scoliosis

Canada
Louisiana State University Health Sciences Center...
National Institute of Dental and Craniofacial Research (NIDCR); Implant Innovations

Unknown

Evaluation of Implants Placed Immediately or Delayed Into Extraction Sites

Dental Caries

United States
University of Hawaii
Kaiser Permanente; RTI International; Centers for Medicare and Medicaid Services and other collaborators

Completed

Hawaii Patient Reward And Incentives to Support Empowerment (HI-PRAISE)

Diabetes Mellitus

United States
SEAMEO Regional Centre for Food and Nutrition
London School of Hygiene and Tropical Medicine; University College, London; University... and other collaborators

Recruiting

Egg Intervention During Pregnancy in Indonesia (PRECODE)

Protozoan Infections | Birth Weight | Weight Gain | Vitamin A Deficiency | Folate Deficiency | Zinc Deficiency | Child Development | Salmonella Infections | Anemia, Iron Deficiency | Fatty Acid Deficiency | Birth Length | B12 Deficiency Vitamin | Mineral Deficiency | E. Coli Infection | Shigella Infection | Amino Acid Deficiency and other conditions

Indonesia
Sanford Health
National Ataxia Foundation; Beyond Batten Disease Foundation; Pitt Hopkins Research... and other collaborators

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (CoRDS)

Mitochondrial Diseases | Retinitis Pigmentosa | Myasthenia Gravis | Eosinophilic Gastroenteritis | Multiple System Atrophy | Leiomyosarcoma | Leukodystrophy | Anal Fistula | Spinocerebellar Ataxia Type 3 | Friedreich Ataxia | Kennedy Disease | Lyme Disease | Hemophagocytic Lymphohistiocytosis | Spinocerebellar Ataxia... and other conditions

United States, Australia
Baskent University Ankara Hospital
Pamukkale University; Hacettepe University; Kanuni Sultan Suleyman Training and... and other collaborators

Recruiting

Evaluation of the Frequency, Risk Factors, and Outcomes of ROP in Infants With a BW >1500 Grs or GA ≥33 Wks in Turkey. (TR-BigROP)

Retinopathy of Prematurity

Turkey

Clinical Trials Sponsored by ImPACT Applications, Inc.

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Guinea

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations