Clinical Trials Sponsored by Institute of Child Health, London, England

Total 2445 results

Public Health England
Department of Health, United Kingdom; Institute of Child Health, London, England

Completed

Hepatitis B Vaccination in Infants (Infanrix)

Pneumococcal Disease | Meningococcal Disease | Diphtheria, Tetanus and Pertussis | Haemophilus Influenzae Serotype b Disease | Hepatitis b

United Kingdom
Public Health England
Imperial College London; Institute of Child Health

Withdrawn

Assessment of Novel Pneumococcal Conjugate Vaccination Scheduled in UK Infants (PINC)

Vaccination | Immunization

United Kingdom
Public Health England
Institute of Child Health

Completed

A Phase III/IV Open-label Study of the Immunogenicity and Safety of a Single Dose of a Live Attenuated Influenza Vaccine (LAIV) (FluenzTM) for Each of Three Successive Years in Children naïve to, or in Previous Receipt of the AS03B Adjuvanted H1N1 (2009) Influenza Vaccine (Pandemrix ™). (LAIV Immuno)

Live Attenuated Influenza Vaccine

United Kingdom
Public Health England
Institute of Child Health; St George's, University of London

Completed

A Trial Comparing Two Pertussis-containing Vaccines in Pregnancy and Vaccine Responses in UK Mothers and Their Infants (iMAP2)

Responses to Infant Immunisations

United Kingdom
St George's, University of London
Public Health England

Recruiting

Propositive (Protecting Positive People From Meningococcal Infection) Follow-up Study

HIV/AIDS | Meningococcal Disease

United Kingdom
Public Health England
Institute of Child Health; National Institute of Biological Standards and Control

Completed

Study to Evaluate the Immune Response of United Kingdom (UK) Infants Receiving DTaP/Hib/IPV, Meningococcal C Conjugate and Pneumococcal Conjugate Vaccines, Antibody Persistence and Responses to Booster Doses in the Second Year of Life (Sched2)

Pneumococcal Infections | Meningococcal Infections

United Kingdom
Queen Mary University of London
University College, London; Public Health England

Completed

Completion and Acceptability of Treatment Across Primary Care and the commUnity for Latent Tuberculosis (CATAPULT)

Latent Tuberculosis

United Kingdom
University of Oxford
Imperial College London; Public Health England

Unknown

Genetic Susceptibility to Severe Streptococcal Infections

Invasive Streptococcal Infection | Invasive Group A Streptococcal Disease | Invasive Group B Streptococcal Disease | Necrotising Fasciitis

United Kingdom
University of Oxford
University College, London; Public Health England

Completed

Baby Vaccine Study (Sched3)

Infectious Diseases

United Kingdom
St George's, University of London
GlaxoSmithKline; Public Health England; MeningitisNow

Completed

Babies Born Early Antibody Response to Men B Vaccination: BEAR Men B (BEAR Men B)

Prematurity | Meningococcal Disease | Vaccination

United Kingdom
Institute of Child Health

Completed

RCT of the Efficacy of the Ketogenic Diet in the Treatment of Epilepsy

Epilepsy

United Kingdom
Institute of Child Health

Completed

Pain of Injection of Lipuro Propofol in Children Aged 1-7 Years

ASA 1-2 Requiring Intravenous Cannulation for General Anaesthesia

United Kingdom
Institute of Child Health

Completed

Clinical Outcome of Laparoscopic Versus Open Nissen Fundoplication in Children: 3-Year Follow-up Study of Randomized Controlled Trial.

Gastro -Oesophagal Reflux

United Kingdom
Institute of Child Health

Completed

Randomised Double Blind Placebo Controlled Cross Over Design of the Efficacy of Topical Morphine for Inflammatory Pain in Children With Epidermolysis Bullosa

Epidermylosis Bullosa

United Kingdom
Institute of Child Health

Completed

Laparoscopy in Children: Does it Decrease the Metabolic, Endocrine and Inflammatory Stress Response to Surgery

Gastro-Oesophageal Reflux

United Kingdom
Institute of Child Health

Completed

Vitamins and Minerals for Children With Downs Syndrome

Trisiomy 21 (Down Syndrome)

United Kingdom
Institute of Child Health

Completed

Urokinase Versus Primary Video-Assisted Thorascopic Surgery for Empyema

Empyema

United Kingdom
Institute of Child Health

Enrolling by invitation

Homonymous Hemianopia in Childhood (HHIC)

Homonymous Hemianopia

United Kingdom
Institute of Child Health

Completed

CATCH - Catheter Infections in Children

Catheter-related Infections

United Kingdom
Institute of Child Health

Terminated

Open vs Laparoscopic Pyloromyotomy for Pyloric Stenosis

Pyloric Stenosis

United Kingdom
Institute of Child Health

Completed

Overcoming Perfectionism: A Randomised Controlled Trial of an Online CBT Based Guided Self-help Intervention

Perfectionism

United Kingdom
Institute of Child Health

Unknown

Evaluating PEGASUS - a Group Intervention for Young People With an Autism Spectrum Disorder

Efficacy of PEGASUS

United Kingdom
Institute of Child Health

Unknown

A Trial Comparing Two Breast Pumps in Mothers Expressing Milk for Their Preterm Infants

Milk Production

United Kingdom
Institute of Child Health

Unknown

Long Term Tapering or Standard Steroids for Nephrotic Syndrome

Nephrotic Syndrome

United Kingdom
Institute of Child Health

Completed

Double Blind Randomized Study Into the Efficacy of Codeine Phosphate Analgesia After Cleft Palate Repair in Infants

Cleft Palate Repair

United Kingdom
Institute of Child Health

Unknown

Prevention Of Morbidity In Sickle Cell Disease Pilot Phase

Sickle Cell Anaemia

United Kingdom
Institute of Child Health

Unknown

Feeding Bottle Design, Milk Intake and Infant Growth

Healthy Infants

United Kingdom
Institute of Child Health

Unknown

PRINTO (the Paediatric Rheumatology International Trials Organisation)

Juvenile Idiopathic Arthritis

United Kingdom
Institute of Child Health

Completed

The Effect of Caudal Volumes on the Anatomical Spread of Caudals in Children

Asa 1 and 2 Patients for Elective Surgery Requiring Caudal as Part of Their Care

United Kingdom
Institute of Child Health

Completed

Trial of Nutritional Supplementation in Infants Born Small for Gestational Age

Birth Weight

United Kingdom
Institute of Child Health

Completed

The Great Ormond Street Hospital Top Child and Adolescent Health Study

Parents | Child Behavior | Adolescent Behavior

United Kingdom
Institute of Child Health

Completed

Minimal Access Repair of Contralateral Hernias (MARCH Trial)

Unilateral Inguinal Hernia

United Kingdom
Institute of Child Health

Completed

Neuropathic Pain in Children: Multimodal Assessment and Diagnosis

Neuropathic Pain | Child, Only

United Kingdom
Institute of Child Health

Completed

Microbial Invasion During Parenteral Nutrition in Surgical Infants Receiving Glutamine

Surgical Infants Requiring Total Parenteral Nutrition

United Kingdom
Institute of Child Health

Completed

Macrolide in Pregnancy and Adverse Child Outcomes

Infection
Institute of Child Health

Completed

Trim Tots Pre-school Obesity Prevention Programme (TrimTots)

Obesity | Overweight

United Kingdom
Institute of Child Health

Completed

Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PONTI Study)

Recurrent Neural Tube Defects

United Kingdom
Institute of Child Health

Unknown

Trial of the MEND Childhood Obesity Treatment Program (MEND)

Obesity
Institute of Child Health

Unknown

Community-Based Interventions for Infant Health in Nepal

Child Mortality

United Kingdom
Institute of Child Health

Unknown

The Impact of Reducing Overtreatment on Quality of Life in Children With Refractory Epilepsy

Intractable Epilepsy

United Kingdom
Institute of Child Health

Completed

Prediction of Childhood Epilepsy Outcome in Bangladesh

Epilepsy

United Kingdom, Bangladesh
King's College London
Public Health England; National Institute for Health Research, United Kingdom

Completed

Improving the Behavioural Impact of Air Quality Alerts

Health Behavior | Pollution; Exposure

United Kingdom
King's College London
Public Health England; National Institute for Health Research, United Kingdom

Completed

Improving Communication During a Pandemic Flu Outbreak

Healthy
Public Health England
Imperial College London; University College, London; Queen Mary University of... and other collaborators

Completed

Prognostic Value of Interferon Gamma Release Assays in Predicting Active Tuberculosis Among Individuals With, or at Risk of, Latent Tuberculosis Infection (PREDICT)

Latent Tuberculosis | Tuberculosis

United Kingdom
Barts & The London NHS Trust
Bristol Royal Infirmary; Institute of Child Health

Completed

Alternative Substrates in the Critically Ill Subject (ASICS)

Critical Illness

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Institute of Child Health, University College London, London, UK.

Completed

Mycophenolate Mofetil in Systemic Lupus Erythematosus (MISSILE) (MISSILE)

Systemic Lupus Erythematosus | Atherosclerosis

United Kingdom
Institute of Cancer Research, United Kingdom
Public Health England

Completed

Feasibility Study Testing Transcriptional Responses as an Indicator of Individualised Responses to Radiation Effects (RTGene)

Cancer

United Kingdom
Institute of Cancer Research, United Kingdom
Public Health England

Active, not recruiting

Transcriptional Responses as an Indicator of Individualised Responses to Radiation Effects (RTGene 2)

Cancer

United Kingdom
University of Oxford
Imperial College London; Public Health England; Novartis Vaccines; European Commission

Completed

Investigating the Immune Response to 4CMenB in Infants

Meningitis

United Kingdom
St George's, University of London
University of Nottingham; Medical Research Council; Public Health England

Recruiting

Development of a Serocorrelate of Protection Against Invasive Group B Streptococcus Disease (iGBS3)

Streptococcus Agalactiae Infection

United Kingdom

Clinical Trials Sponsored by Institute of Child Health, London, England

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