Clinical Trials Sponsored by Institute of Rheumatology, Prague

Total 331 results

Institute of Rheumatology, Prague
Karolinska Institutet

Completed

Combined Treatment of Methotrexate + Glucocorticoids Versus Glucocorticoids Alone in Patients With PM and DM (Prometheus)

Dermatomyositis | Polymyositis

Czech Republic
Karolinska Institutet
King's College Hospital NHS Trust; Institute of Rheumatology, Prague

Completed

Abatacept Treatment in Polymyositis and Dermatomyositis (ARTEMIS)

Dermatomyositis | Polymyositis

Sweden, Czechia
Institute of Rheumatology, Prague
Charles University, Czech Republic; Palacky University; Ministry of Health, Czech... and other collaborators

Completed

Cyclosporine A or Intravenous Cyclophosphamide for Lupus Nephritis: The Cyclofa-Lune Study (CYCLOFA-LUNE)

Systemic Lupus Erythematosus | Lupus Nephritis

Czech Republic
General University Hospital, Prague
Charles University, Czech Republic; Institute of Hematology and Blood Transfusion...

Recruiting

Selected Immunological Indicators and Microbiota in Patients With Premature Birth and Preeclampsia (PRIME)

Preterm Birth | Preeclampsia

Czechia
Ruth Tachezy, PhD.
Na Homolce Hospital; Medical Healthcom Prague

Completed

Effect of Vaccination in Patients With Recurrent Respiratory Papillomatosis

Squamous Papilloma of the Larynx

Czechia
Chinese Society of Hematology
Harbin Institute of Hematology & Oncology

Unknown

Myelodysplastic Syndrome--CDA-2 Hematological Improvement National Affirmation Study (MD-CHINA)

Myelodysplastic Syndrome (MDS)
AeskuLab Pathology Prague
Institute of Biostatistics and analyses, Ltd.

Completed

Algorithm for Cervix Carcinoma Screening in CZ Using the Detection of HPV DNA and CINtec Plus (LIBUSE)

Algorithm for Cervix Carcinoma Screening

Czechia
Institute for the Care of Mother and Child, Prague...
General University Hospital, Prague; Bulovka Hospital

Not yet recruiting

Prevalence of Intrauterine Adhesions After D&C With or Without Antiadhesion Gel After Abortion in Second Trimester. (ADAB)

Asherman Syndrome | Abortion Late
Federal State Budgetary Scientific Institution,...
The League of Clinical Research, Russia; Institute of Biomedical Chemistry,...

Completed

"Corticoid-16" in Long Term When Administered Systemically in Patients in Routine Medical Practice

Pharmacological Action
V.A. Nasonova Research Institute of Rheumatology...
AstraZeneca

Not yet recruiting

Evaluation of Type I IFN Level and Disease Activity in SLE Patients

Elevated Level of IFN Type I in SLE Patients
Abbott
Almedis; Scientific Research Institute of Rheumatology, Moscow

Completed

Study to Characterize Demographics, Compliance, Tolerability and Safety in Patients With Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis Prescribed Adalimumab (Humira®) as Part of Routine Clinical Care

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis

Russian Federation
National Institute of Geriatrics, Rheumatology...

Not yet recruiting

Medial Wedge Insoles to Improve Gait in Persons After Total Hip Replacement

Surgical Procedure, Unspecified | Fracture of Femur | Arthritis of Hip | Dysplasia; Hip | Aseptic Necrosis
National Institute of Geriatrics, Rheumatology...

Completed

Physical and Psychological Changes in CRPS Patients Undergoing Multimodal Rehabilitation

Complex Regional Pain Syndromes

Poland
Institute of Hematology & Blood Diseases Hospital

Recruiting

Growth and Development-related Outcomes in Children With Transfusion-dependent Beta-thalassemia After Gene Therapy

Gene Therapy | Transfusion-dependent Beta-Thalassemia

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by BCMA CAR-T Therapy in Transplant-Ineligible Patients With Primary Plasma Cell Leukemia

Plasma Cell Leukemia

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

Cyclophosphamide Added to Standard Immunosuppressive Therapy With Eltrombopag as Front-line Therapy in Patients With Severe Aplastic Anemia

Severe Aplastic Anemia

China
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Humanized Anti-CD25 Antibody for Prophylaxis of aGVHD in Elderly Underwent HID-HSCT

The Effecacy and Safety of Humanized CD25 Antibody in aGVHD Prophylaxis Among Elderly Patients After HID-HSCT
Institute of Hematology & Blood Diseases Hospital

Recruiting

Pegylated Interferon α-2b in Combination With Ruxolitinib for Treating Hydroxyurea-resistant/Intolerant PV (PV)

Polycythemia Vera

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

An Exploratory Study of Cluster of Differentiation 38 (CD38) Monoclonal Antibody Combined Corticosteroid in Acquired Hemophilia A (AHA2023)

Acquired Hemophilia

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

BCMA CAR-T Cell Therapy in High-risk NDMM Patients With Positive MRD After First-line ASCT

Multiple Myeloma

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

Hetrombopag for the Enhancement of Platelet Engraftment After Allogeneic Hematopoietic Stem Cell Transplantation

Allogeneic Hematopoietic Stem Cell Transplantation | Hematological Disease

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

Avatrombopag Combined With IST as First-line Treatment for SAA

Severe Aplastic Anemia

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

A Prospective, One-arm and Open Clinical Study of CM313 in the Treatment of Immune Thrombocytopenia (2022-CM313-ITP)

Immune Thrombocytopenia | Treatment

China
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

A Study to Evaluate the Safety and Efficacy of ZS801 in Adult Hemophilia B Patients

Hemophilia B

China
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

A Study of Olverembatinib Combined With Inotuzumab Ozogamicin in the Treatment ph+ ALL With MRD Persistent Positive

Minimal Residual Disease | Bone Marrow Transplant | Ph+ ALL

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

Natural Killer(NK) Cell Therapy for AML Minimal Residual Disease

Minimal Residual Disease

China
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

A Clinical Trial to Assess Safety and Efficacy of Daratumumab in the Treatment of Primary Immune Thrombocytopenia

Immune Thrombocytopenia
Institute of Hematology & Blood Diseases Hospital

Recruiting

A Study of PEG-rhG-CSF and rhG-CSF Used for Aplastic Anemia Granulocyte Deficiency

Severe Aplastic Anemia

China
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Efficacy and Safety of Inotuzumab Ozogamicin in Treating Adult Patients With Ph Negative ALL With Minimal Residual Disease Positive After Induction Chemotherapy

Acute Lymphocytic Leukemia
Institute of Hematology & Blood Diseases Hospital

Recruiting

Efficacy and Safety of CSA and Avatrombopag for the Treatment of SAA in the Elderly (SAA)

Severe Aplastic Anemia

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

Efficacy of Venetoclax Based Regimen in Prevention Relapse of Consecutive MRD Positive AML Patients

Acute Myeloid Leukemia | Measurable Disease

China
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Intensive Therapy Combined With Venetoclax for Adult Acute Myeloid Leukemia

Acute Myeloid Leukemia
Institute of Hematology & Blood Diseases Hospital

Recruiting

Combined Haploidentical and Umbilical Cord Blood Allogeneic Stem Cell Transplantation in Patients With Acute Leukemia

Acute Leukemia

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

Zanubrutinib, Ixazomib and Dexamethasone in Patients With Treatment Naive Waldenstrom's Macroglobulinemia

Waldenström Macroglobulinemia

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

A Prospective Multicenter Phase 2 Study of FCR/BR Alternating With Ibrutinib in Treatment-naive Patients With CLL (BDHCLL001)

Chronic Lymphocytic Leukemia

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

DLCL002 Protocol for Patients With High Risk Aggressive B-cell Lymphoma

Diffuse Large B Cell Lymphoma | High-grade B-cell Lymphoma | Transformed Lymphoma

China
Institute of Hematology & Blood Diseases Hospital

Completed

The Application of Ursodeoxycholic Acid for the Prevention of SARS-CoV-2 Infection (COVID-19)

COVID-19

China
Institute of Hematology & Blood Diseases Hospital

Terminated

Efficacy and Safety of Low-dose Decitabine in Refractory Aplastic Anemia (LODACA)

Refractory Aplastic Anemia

China
Institute of Hematology & Blood Diseases Hospital

Completed

Dasatinib Combined With Chemotherapy in Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia

Acute,Leukemia, Lymphoid

China
Institute of Hematology & Blood Diseases Hospital

Unknown

A Study of BCMA-directed CAR-T Cells Treatment in Subjects With r/r Multiple Myeloma

Multiple Myeloma

China
Institute of Hematology & Blood Diseases Hospital

Completed

Efficacy and Safety of rhTPO for the Treatment of Thrombocytopenia After Chemotherapy in AML Patients

Thrombocytopenia

China
Institute of Hematology & Blood Diseases Hospital

Unknown

Efficacy and Safety of ATO Plus ATRA in Nucleophosmin-1 Mutated Acute Myeloid Leukemia

AML

China
Institute of Hematology & Blood Diseases Hospital

Unknown

Efficacy of Idarubicin, Cytarabine and Cyclophosphamide (IAC) Regimen in Relapsed/Refractory AML

Acute Myeloid Leukemia

China
Institute of Hematology & Blood Diseases Hospital

Unknown

Comparison of ASCT and Conventional Chemotherapy in High Risk Waldenström Macroglobulinemia (BDH-WM03)

Waldenström Macroglobulinemia

China
Institute of Hematology & Blood Diseases Hospital

Unknown

Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Classic Paroxysmal Nocturnal Hemoglobinuria (PNH-2012)

Urination Disorders | Thrombosis | Proteinuria | Anemia, Hemolytic | Hemoglobinuria, Paroxysmal | Hemoglobinuria | Paroxysmal Nocturnal Hemoglobinuria | Bone Marrow Failure | Aplastic Anemia,

China
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Ruxolitinib as GVHD Prophylaxis in AA Patients

The Prophylactic Value of Ruxolitinib for aGVHD in HSCT Recipients of AA
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Letermovir for Primary Prophylaxis of Cytomegalovirus Infection After R+HID-HSCT

The Incidence of Peripheral Blood CMV Activation and Confirmed Clinically Significant CMV Infection Within 24 Weeks After Transplantation
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

Secondary Prophylaxis of CMV Infection Using Letermovir After HID-HSCT

To Evaluate the Efficacy and Safety of Secondary Prophylaxis of CMV Reactivation
Institute of Hematology & Blood Diseases Hospital

Recruiting

A Study to Evaluate the Safety and Efficacy of COVID-19 Convalescent Plasma (CCP) Transfusion to Prevent COVID-19 in Adult Recipients Following Hematopoietic Stem Cell Transplantation

COVID-19 | Hematopoietic Stem Cell Transplantation

China
Institute of Hematology & Blood Diseases Hospital

Recruiting

Obinutuzumab in Combination With Lenalidomide in Relapsed or Refractory Follicular Lymphoma in Real World Study

Follicular Lymphoma

China

Clinical Trials Sponsored by Institute of Rheumatology, Prague

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